{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T00:08:03Z","timestamp":1759018083844,"version":"3.44.0"},"reference-count":15,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2005,12,1]],"date-time":"2005-12-01T00:00:00Z","timestamp":1133395200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2005,12,1]],"date-time":"2005-12-01T00:00:00Z","timestamp":1133395200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","journalofinfection.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Infection"],"published-print":{"date-parts":[[2005,12]]},"DOI":"10.1016\/j.jinf.2004.11.011","type":"journal-article","created":{"date-parts":[[2005,1,13]],"date-time":"2005-01-13T08:49:19Z","timestamp":1105606159000},"page":"408-412","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["The effect of infection with Mycobacterium tuberculosis on T-cell activation and proliferation in patients with and without HIV co-infection"],"prefix":"10.1016","volume":"51","author":[{"given":"Jorge S.","family":"Villacian","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guat Bee","family":"Tan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lian Fang","family":"Teo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicholas I.","family":"Paton","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"8","key":"10.1016\/j.jinf.2004.11.011_bib1","doi-asserted-by":"crossref","first-page":"678","DOI":"10.7326\/0003-4819-114-8-678","article-title":"NIH conference. Immunopathogenic mechanisms in human immunodeficiency virus (HIV) infection","volume":"114","author":"Fauci","year":"1991","journal-title":"Ann Intern Med"},{"issue":"7","key":"10.1016\/j.jinf.2004.11.011_bib2","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1038\/nm0798-794","article-title":"Limited CD4+ T-cell renewal in early HIV-1 infection: effect of highly active antiretroviral therapy","volume":"4","author":"Fleury","year":"1998","journal-title":"Nat Med"},{"issue":"5","key":"10.1016\/j.jinf.2004.11.011_bib3","doi-asserted-by":"crossref","first-page":"1279","DOI":"10.1086\/314451","article-title":"Activation and cell cycle antigens in CD4+ and CD8+ T cells correlate with plasma human immunodeficiency virus (HIV-1) RNA level in HIV-1 infection","volume":"178","author":"Orendi","year":"1998","journal-title":"J Infect Dis"},{"issue":"3","key":"10.1016\/j.jinf.2004.11.011_bib4","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1097\/00126334-200011010-00001","article-title":"The dominant source of CD4+ and CD8+ T-cell activation in HIV infection is antigenic stimulation","volume":"25","author":"Cohen Stuart","year":"2000","journal-title":"J Acquir Immune Defic Syndr"},{"key":"10.1016\/j.jinf.2004.11.011_bib5","doi-asserted-by":"crossref","first-page":"3509","DOI":"10.4049\/jimmunol.156.9.3509","article-title":"Programmed cell death in peripheral lymphocytes from HIV-infected persons: increased susceptibility to apoptosis of CD4 and CD8 T cells correlates with lymphocyte activation and with disease progression","volume":"156","author":"Gougeon","year":"1996","journal-title":"J Immunol"},{"issue":"10","key":"10.1016\/j.jinf.2004.11.011_bib6","doi-asserted-by":"crossref","first-page":"1534","DOI":"10.1086\/374786","article-title":"T cell activation is associated with lower CD4+ T cell gains in human immunodeficiency virus-infected patients with sustained viral suppression during antiretroviral therapy","volume":"187","author":"Hunt","year":"2003","journal-title":"J Infect Dis"},{"issue":"8","key":"10.1016\/j.jinf.2004.11.011_bib7","doi-asserted-by":"crossref","first-page":"1295","DOI":"10.1084\/jem.187.8.1295","article-title":"Turnover of CD4+ and CD8+ T lymphocytes in HIV-1 infection as measured by Ki-67 antigen","volume":"187","author":"Sachsenberg","year":"1998","journal-title":"J Exp Med"},{"issue":"1","key":"10.1016\/j.jinf.2004.11.011_bib8","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1046\/j.1365-2249.1996.907600.x","article-title":"Generalized immune activation in pulmonary tuberculosis: co-activation with HIV infection","volume":"103","author":"Vanham","year":"1996","journal-title":"Clin Exp Immunol"},{"issue":"9","key":"10.1016\/j.jinf.2004.11.011_bib9","doi-asserted-by":"crossref","first-page":"1405","DOI":"10.1086\/319855","article-title":"Human immunodeficiency virus Type 1 (HIV-1) plasma virus load and markers of immune activation among HIV-infected female sex workers with sexually transmitted diseases in Abidjan, Cote d'Ivoire","volume":"183","author":"Nkengasong","year":"2001","journal-title":"J Infect Dis"},{"issue":"1","key":"10.1016\/j.jinf.2004.11.011_bib10","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1046\/j.1365-2249.2002.01809.x","article-title":"Immunophenotypic characterization of peripheral T lymphocytes in Mycobacterium tuberculosis infection and disease","volume":"128","author":"Rodrigues","year":"2002","journal-title":"Clin Exp Immunol"},{"issue":"3","key":"10.1016\/j.jinf.2004.11.011_bib11","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1046\/j.1365-2249.2000.01385.x","article-title":"T cell activation, apoptosis and cytokine dysregulation in the (co)pathogenesis of HIV and pulmonary tuberculosis (TB)","volume":"122","author":"Hertoghe","year":"2000","journal-title":"Clin Exp Immunol"},{"issue":"1","key":"10.1016\/j.jinf.2004.11.011_bib12","first-page":"23","article-title":"Pulmonary tuberculosis: decreased activation of T lymphocyte subsets in vitro","volume":"1","author":"Kovalchuk","year":"1996","journal-title":"Russ J Immunol"},{"issue":"1","key":"10.1016\/j.jinf.2004.11.011_bib13","first-page":"53","article-title":"T cell functional disturbances in patients with pulmonary tuberculosis","volume":"5","author":"Ostanin","year":"2000","journal-title":"Russ J Immunol"},{"issue":"12","key":"10.1016\/j.jinf.2004.11.011_bib14","doi-asserted-by":"crossref","first-page":"1967","DOI":"10.1086\/375346","article-title":"Human immunodeficiency virus-1 RNA levels and CD4 lymphocyte counts, during treatment for active tuberculosis, in South African patients","volume":"187","author":"Morris","year":"2003","journal-title":"J Infect Dis"},{"issue":"1","key":"10.1016\/j.jinf.2004.11.011_bib15","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1165\/rcmb.4840","article-title":"Recruitment of antigen-specific Th1-like responses to the human lung following bronchoscopic segmental challenge with purified protein derivative of Mycobacterium tuberculosis","volume":"29","author":"Silver","year":"2003","journal-title":"Am J Respir Cell Mol Biol"}],"container-title":["Journal of Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0163445304002749?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0163445304002749?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T15:28:24Z","timestamp":1758986904000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0163445304002749"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,12]]},"references-count":15,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2005,12]]}},"alternative-id":["S0163445304002749"],"URL":"https:\/\/doi.org\/10.1016\/j.jinf.2004.11.011","relation":{},"ISSN":["0163-4453"],"issn-type":[{"type":"print","value":"0163-4453"}],"subject":[],"published":{"date-parts":[[2005,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The effect of infection with Mycobacterium tuberculosis on T-cell activation and proliferation in patients with and without HIV co-infection","name":"articletitle","label":"Article Title"},{"value":"Journal of Infection","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jinf.2004.11.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2004 The British Infection Society. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}