{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T18:14:32Z","timestamp":1780078472231,"version":"3.54.0"},"reference-count":37,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2013,3,1]],"date-time":"2013-03-01T00:00:00Z","timestamp":1362096000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,3,1]],"date-time":"2013-03-01T00:00:00Z","timestamp":1362096000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","journalofinfection.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Infection"],"published-print":{"date-parts":[[2013,3]]},"DOI":"10.1016\/j.jinf.2012.11.002","type":"journal-article","created":{"date-parts":[[2012,11,19]],"date-time":"2012-11-19T04:17:03Z","timestamp":1353298623000},"page":"278-284","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":29,"title":["Risk factors and outcomes of Candida krusei bloodstream infection: A matched, case-control study"],"prefix":"10.1016","volume":"66","author":[{"given":"Mindy G.","family":"Schuster","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Meibohm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa","family":"Lloyd","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian","family":"Strom","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jinf.2012.11.002_bib1","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1016\/j.ijantimicag.2006.01.002","article-title":"Candidaemia in Europe: epidemiology and resistance","volume":"27","author":"Tortorano","year":"2006","journal-title":"Int J Antimicrob Agents"},{"key":"10.1016\/j.jinf.2012.11.002_bib2","doi-asserted-by":"crossref","first-page":"4745","DOI":"10.1002\/cncr.24507","article-title":"Candidemia in patients with hematologic malignancies in the era of new antifungal agents (2001\u20132007)","volume":"15","author":"Sipsas","year":"2009","journal-title":"Cancer"},{"key":"10.1016\/j.jinf.2012.11.002_bib3","doi-asserted-by":"crossref","first-page":"1519","DOI":"10.1128\/JCM.42.4.1519-1527.2004","article-title":"Incidence of bloodstream infections due to Candida species and in\u00a0vitro susceptibilities of isolates collected from 1998 to 2000 in a population-based active surveillance program","volume":"42","author":"Hajjeh","year":"2004","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.jinf.2012.11.002_bib4","doi-asserted-by":"crossref","first-page":"3551","DOI":"10.1128\/JCM.40.10.3551-3557.2002","article-title":"Role of sentinel surveillance of candidaemia: trends in species distribution and antifungal susceptibility","volume":"40","author":"Pfaller","year":"2002","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.jinf.2012.11.002_bib5","doi-asserted-by":"crossref","first-page":"3254","DOI":"10.1128\/JCM.39.9.3254-3259.2001","volume":"39","author":"Pfaller","year":"2001","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.jinf.2012.11.002_bib6","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1086\/376906","article-title":"A prospective observational study of candidemia: epidemiology, therapy, and influences on mortality in hospitalized adult and pediatric patients","volume":"37","author":"Pappas","year":"2003","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.jinf.2012.11.002_bib7","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1016\/S0002-9343(95)00010-0","article-title":"The changing face of candidemia: emergence of non-Candida albicans species and antifungal resistance","volume":"10","author":"Nguyen","year":"1996","journal-title":"Am J Med"},{"key":"10.1016\/j.jinf.2012.11.002_bib8","doi-asserted-by":"crossref","first-page":"2493","DOI":"10.1002\/cncr.23466","article-title":"The changing epidemiology of invasive candidiasis","volume":"112","author":"Hachem","year":"2008","journal-title":"Cancer"},{"key":"10.1016\/j.jinf.2012.11.002_bib9","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1016\/S0002-9343(01)01130-5","article-title":"The epidemiology of Candida glabrata and Candida albicans fungemia in immunocompromised patients with cancer","volume":"112","author":"Bodey","year":"2002","journal-title":"Am J Med"},{"key":"10.1016\/j.jinf.2012.11.002_bib10","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.ijantimicag.2011.02.016","article-title":"Candida bloodstream infections: comparison of species distribution and resistance to echinocandin and azole antifungal agents in intensive care unit (ICU) and non-ICU settings in the SENTRY antimicrobial surveillance program (2008\u20132009)","volume":"38","author":"Pfaller","year":"2011","journal-title":"Int J Antimicrob Agents"},{"key":"10.1016\/j.jinf.2012.11.002_bib11","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1093\/clinids\/20.1.115","article-title":"Importance of Candida species other than C. albicans as pathogens in oncology patients","volume":"20","author":"Wingard","year":"1995","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.jinf.2012.11.002_bib12","doi-asserted-by":"crossref","first-page":"2659","DOI":"10.1001\/archinte.160.17.2659","article-title":"Candida krusei fungemia: an escalating serious infection in immunocompromised patients","volume":"160","author":"Abbas","year":"2000","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.jinf.2012.11.002_bib13","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1053\/jhin.2001.1131","article-title":"Increase in prevalence of nosocomial non-Candida albicans candidaemia and the association of Candida krusei with fluconazole use","volume":"50","author":"Hope","year":"2002","journal-title":"J Hosp Infect"},{"key":"10.1016\/j.jinf.2012.11.002_bib14","doi-asserted-by":"crossref","first-page":"1274","DOI":"10.1056\/NEJM199110313251803","article-title":"Increase in Candida krusei infection among patients with bone marrow transplantation and neutropenia treated prophylactically with fluconazole","volume":"325","author":"Wingard","year":"1991","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jinf.2012.11.002_bib15","doi-asserted-by":"crossref","first-page":"1206","DOI":"10.1086\/529435","article-title":"Factors associated with candidemia caused by non-albicans candida species versus Candida albicans in the intensive care unit","volume":"46","author":"Chow","year":"2008","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.jinf.2012.11.002_bib16","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1111\/j.1469-0691.2009.02821.x","article-title":"Candidemia with uncommon Candida species; predisposing factors, outcome antifungal susceptibility, and implications for management","volume":"15","author":"Chen","year":"2009","journal-title":"Clin Microbiol Infect"},{"key":"10.1016\/j.jinf.2012.11.002_bib17","doi-asserted-by":"crossref","first-page":"1676","DOI":"10.1111\/j.1469-0691.2010.03208.x","article-title":"Predictors of candidaemia caused by non-albicans Candida species: results of a population-based surveillance in Barcelona, Spain","volume":"16","author":"Rodriguez","year":"2010","journal-title":"Clin Microbiol Infect"},{"key":"10.1016\/j.jinf.2012.11.002_bib18","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1128\/AAC.01128-10","article-title":"Recent exposure to caspofungin or fluconazole influences the epidemiology of candidemia: a prospective multicenter study involving 2,441 patients","volume":"55","author":"Lortholary","year":"2010","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.jinf.2012.11.002_bib19","first-page":"113","article-title":"Fluconazole and Candida krusei fungemia","volume":"325","author":"Persons","year":"1991","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jinf.2012.11.002_bib20","doi-asserted-by":"crossref","first-page":"1122","DOI":"10.1086\/513663","article-title":"The epidemiology of hematogenous candidiasis caused by different candida species","volume":"24","author":"Abi-Said","year":"1997","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.jinf.2012.11.002_bib21","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1001\/archsurg.1997.01430350047008","article-title":"Emerging evidence of selection of fluconazole-tolerant fungi in surgical intensive care units","volume":"132","author":"Gleason","year":"1997","journal-title":"Arch Surg"},{"key":"10.1016\/j.jinf.2012.11.002_bib22","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1097\/01.CCM.0000259379.97694.00","article-title":"Do clinical features allow for accurate prediction of fungal pathogenesis in bloodstream infections? Potential implications of the increasing prevalence of non-albicans candidemia","volume":"35","author":"Shorr","year":"2007","journal-title":"Crit Care Med"},{"key":"10.1016\/j.jinf.2012.11.002_bib23","doi-asserted-by":"crossref","first-page":"1042","DOI":"10.1093\/jac\/dkq053","article-title":"Candidaemia in adult cancer patients: risks for fluconazole-resistant isolates and death","volume":"65","author":"Slavin","year":"2010","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.jinf.2012.11.002_bib24","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1093\/jac\/dkl241","article-title":"Effect of fluconazole consumption on long-term trends in candidal ecology","volume":"58","author":"Blot","year":"2006","journal-title":"J\u00a0Antimicrob Chemother"},{"key":"10.1016\/j.jinf.2012.11.002_bib25","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1056\/NEJM199203263261301","article-title":"A controlled trial of fluconazole to prevent fungal infections in patients undergoing bone marrow transplantation","volume":"326","author":"Goodman","year":"1992","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jinf.2012.11.002_bib26","doi-asserted-by":"crossref","first-page":"495","DOI":"10.7326\/0003-4819-118-7-199304010-00003","article-title":"Fluconazole prophylaxis for fungal infection in patients with acute leukemia: results of a randomized placebo-controlled, double blind, multicenter trial","volume":"118","author":"Winston","year":"1993","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.jinf.2012.11.002_bib27","first-page":"115","article-title":"Use of fluconazole is not associated with a higher incidence of Candida krusei and other non-albicans Candida species","volume":"20","author":"Kunova","year":"1995","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.jinf.2012.11.002_bib28","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1093\/clinids\/20.2.342","article-title":"Invasive infection due to Candida krusei in immunocompromised patients not treated with fluconazole","volume":"20","author":"Iwen","year":"1995","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.jinf.2012.11.002_bib29","doi-asserted-by":"crossref","first-page":"4555","DOI":"10.1128\/AAC.49.11.4555-4560.2005","article-title":"Prior antimicrobial therapy and risk for hospital-acquired Candida glabrata and Candida krusei fungemia; a case-case-control study","volume":"49","author":"Lin","year":"2005","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.jinf.2012.11.002_bib30","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1128\/jcm.24.4.581-584.1986","article-title":"Increased incidence of fungemia caused by Candida krusei","volume":"24","author":"Merz","year":"1986","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.jinf.2012.11.002_bib31","doi-asserted-by":"crossref","first-page":"1531","DOI":"10.1093\/clinids\/20.6.1531","article-title":"Nosocomial candidemia: risk factors and attributable mortality","volume":"20","author":"Wenzel","year":"1995","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.jinf.2012.11.002_bib32","doi-asserted-by":"crossref","first-page":"1172","DOI":"10.1086\/378745","article-title":"Attributable mortality of nosocomial candidemia, revisited","volume":"37","author":"Gudlaugsson","year":"2003","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.jinf.2012.11.002_bib33","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1053\/jhin.2001.1151","article-title":"Non-albicans Candida spp. causing fungemia; pathogenicity and antifungal resistance","volume":"50","author":"Kremery","year":"2002","journal-title":"J Hosp Infect"},{"key":"10.1016\/j.jinf.2012.11.002_bib34","series-title":"Modeling binary data","author":"Collett","year":"2003"},{"issue":"5","key":"10.1016\/j.jinf.2012.11.002_bib35","doi-asserted-by":"crossref","first-page":"e38","DOI":"10.1086\/655698","article-title":"Risk factors and predictors for candidemia in pediatric intensive care unit patients: implications for prevention","volume":"51","author":"Zaoutis","year":"2010","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.jinf.2012.11.002_bib36","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1086\/321811","article-title":"Risk factors for candidal bloodstream infections in surgical intensive care unit patients: the NEMIS prospective multicenter study. The National Epidemiology of Mycosis Survey","volume":"33","author":"Blumberg","year":"2001","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.jinf.2012.11.002_bib37","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1097\/00005792-199305000-00002","article-title":"Candida krusei fungemia: report of 4 cases and review of the literature","volume":"72","author":"Goldman","year":"1993","journal-title":"Medicine"}],"container-title":["Journal of Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0163445312003349?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0163445312003349?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T21:17:57Z","timestamp":1759007877000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0163445312003349"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,3]]},"references-count":37,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2013,3]]}},"alternative-id":["S0163445312003349"],"URL":"https:\/\/doi.org\/10.1016\/j.jinf.2012.11.002","relation":{},"ISSN":["0163-4453"],"issn-type":[{"value":"0163-4453","type":"print"}],"subject":[],"published":{"date-parts":[[2013,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Risk factors and outcomes of Candida krusei bloodstream infection: A matched, case-control study","name":"articletitle","label":"Article Title"},{"value":"Journal of Infection","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jinf.2012.11.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2012 Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}