{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T04:07:39Z","timestamp":1777694859689,"version":"3.51.4"},"reference-count":126,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2015,6,1]],"date-time":"2015-06-01T00:00:00Z","timestamp":1433116800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,6,1]],"date-time":"2015-06-01T00:00:00Z","timestamp":1433116800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","journalofinfection.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Infection"],"published-print":{"date-parts":[[2015,6]]},"DOI":"10.1016\/j.jinf.2015.04.029","type":"journal-article","created":{"date-parts":[[2015,5,2]],"date-time":"2015-05-02T12:40:32Z","timestamp":1430570432000},"page":"S59-S75","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":60,"special_numbering":"S1","title":["The prevention, diagnosis and management of central venous line infections in children"],"prefix":"10.1016","volume":"71","author":[{"given":"Emily","family":"Chesshyre","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zoy","family":"Goff","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Asha","family":"Bowen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonathan","family":"Carapetis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jinf.2015.04.029_bib1","first-page":"1","volume":"vol. 4","author":"Centers for Disease Control and Prevention (CDC)","year":"2014"},{"key":"10.1016\/j.jinf.2015.04.029_bib2","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1093\/cid\/cir523","article-title":"Defining bloodstream infections related to central venous catheters in patients with cancer: a systematic review","volume":"53","author":"Tomlinson","year":"2011","journal-title":"CID"},{"issue":"1","key":"10.1016\/j.jinf.2015.04.029_bib3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1086\/668770","article-title":"Antimicrobial-resistant pathogens associated with healthcare-associated infections: summary of data reported to the national healthcare safety network at the centers for disease control and prevention, 2009\u20132010","volume":"34","author":"Sievert","year":"2013","journal-title":"Infect Control Hosp Epidemiol"},{"issue":"4","key":"10.1016\/j.jinf.2015.04.029_bib4","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1097\/INF.0000000000000113","article-title":"Formal infectious diseases consultations at a tertiary pediatric hospital: a 14-year review","volume":"33","author":"Gwee","year":"2014","journal-title":"Pediatr Infect Dis J"},{"key":"10.1016\/j.jinf.2015.04.029_bib5","doi-asserted-by":"crossref","first-page":"1148","DOI":"10.1016\/j.ajic.2013.09.002","article-title":"National Healthcare Safety\u00a0Network (NHSN) report, data summary for 2012, device-associated module","volume":"41","author":"Dudeck","year":"2013","journal-title":"Am J Infect Control"},{"issue":"12","key":"10.1016\/j.jinf.2015.04.029_bib6","doi-asserted-by":"crossref","first-page":"1200","DOI":"10.1086\/662621","article-title":"Epidemiology of central line-associated bloodstream infections in the pediatric intensive care unit","volume":"32","author":"Niedner","year":"2011","journal-title":"Infect Control Hosp Epidemiol"},{"key":"10.1016\/j.jinf.2015.04.029_bib7","doi-asserted-by":"crossref","first-page":"F9","DOI":"10.1136\/adc.2009.178798","article-title":"Neonatal infections in England: the NeonIN surveillance network","volume":"96","author":"Vergnano","year":"2011","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"key":"10.1016\/j.jinf.2015.04.029_bib8","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1097\/MOP.0b013e328341d1da","article-title":"Prevention of central line associated bloodstream infections in critical care units","volume":"23","author":"Li","year":"2011","journal-title":"Curr Opin Pediatr"},{"key":"10.1016\/j.jinf.2015.04.029_bib9","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/j.ajic.2008.03.002","article-title":"CDC\/NHSN surveillance definition of health-care associated infection and criteria for specific types of infections in the acute care setting","volume":"36","author":"Horan","year":"2008","journal-title":"Am J Infect Control"},{"issue":"3","key":"10.1016\/j.jinf.2015.04.029_bib10","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1016\/j.jhin.2005.08.019","article-title":"Infectious complications of implantable ports and Hickman catheters in paediatric haematology-oncology patients","volume":"62","author":"Adler","year":"2006","journal-title":"J\u00a0Hosp Infect"},{"key":"10.1016\/j.jinf.2015.04.029_bib11","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1016\/j.ijheh.2009.01.003","article-title":"Bloodstream infections in a German paediatric oncology unit: prolongation of inpatient treatment and additional costs","volume":"212","author":"Biwersi","year":"2009","journal-title":"Int J Hyg Environ Health"},{"key":"10.1016\/j.jinf.2015.04.029_bib12","doi-asserted-by":"crossref","first-page":"e1525","DOI":"10.1542\/peds.2013-3795","article-title":"Attributable cost and length of stay for central line-associated bloodstream infections","volume":"133","author":"Goudie","year":"2014","journal-title":"Pediatrics"},{"issue":"2","key":"10.1016\/j.jinf.2015.04.029_bib13","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1542\/peds.114.2.348","article-title":"Marginal increase in cost and excess length of stay associated with nosocomial bloodstream infections in surviving very low birth weight infants","volume":"114","author":"Payne","year":"2004","journal-title":"Pediatrics"},{"key":"10.1016\/j.jinf.2015.04.029_bib14","series-title":"Principles and practice of pediatric infectious diseases","first-page":"588","article-title":"Clinical syndromes of device-associated infections","author":"Gerber","year":"2012"},{"issue":"3","key":"10.1016\/j.jinf.2015.04.029_bib15","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1086\/421946","article-title":"Nosocomial bloodstream infections in US hospitals: analysis of 24,179 cases from a prospective nationwide surveillance study","volume":"39","author":"Wisplinghoff","year":"2004","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.jinf.2015.04.029_bib16","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1378\/chest.118.1.146","article-title":"The influence of inadequate antimicrobial treatment of bloodstream infections on patient outcomes in the ICU setting","volume":"118","author":"Ibrahim","year":"2000","journal-title":"Chest"},{"issue":"12","key":"10.1016\/j.jinf.2015.04.029_bib17","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1097\/01.inf.0000190059.54356.f3","article-title":"Outbreak of Ralstonia pickettii bacteremia in a neonatal intensive care unit","volume":"24","author":"Kimura","year":"2005","journal-title":"Pediatr Infect Dis J"},{"key":"10.1016\/j.jinf.2015.04.029_bib18","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.4065\/81.9.1159","article-title":"The risk of bloodstream infection in adults with different intravascular devices: a systematic review of 200 published prospective studies","volume":"81","author":"Maki","year":"2006","journal-title":"Mayo Clin Proc"},{"key":"10.1016\/j.jinf.2015.04.029_bib19","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1093\/infdis\/168.2.400","article-title":"Ultrastructural analysis of indwelling vascular catheters: a quantitative relationship between luminal colonization and duration of placement","volume":"168","author":"Raad","year":"1993","journal-title":"J Infect Dis"},{"key":"10.1016\/j.jinf.2015.04.029_bib20","doi-asserted-by":"crossref","first-page":"881","DOI":"10.3201\/eid0809.020063","article-title":"Biofilms: microbial life on surfaces","volume":"8","author":"Donlan","year":"2002","journal-title":"Emerg Infect Dis"},{"issue":"6","key":"10.1016\/j.jinf.2015.04.029_bib21","doi-asserted-by":"crossref","first-page":"1771","DOI":"10.1128\/JCM.37.6.1771-1776.1999","article-title":"The Calgary Biofilm device: new technology for rapid determination of antibiotic susceptibilities for bacterial biofilms","volume":"37","author":"Ceri","year":"1999","journal-title":"J\u00a0Clin Microbiol"},{"key":"10.1016\/j.jinf.2015.04.029_bib22","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.1097\/INF.0b013e3181bf7bfc","article-title":"Diagnosis and management of Central venous catheter-related bloodstream infections in paediatric patients","volume":"28","author":"Flynn","year":"2009","journal-title":"Pediatr Infect Dis J"},{"issue":"8","key":"10.1016\/j.jinf.2015.04.029_bib23","first-page":"905","article-title":"Central line-associated blood stream infection in children: an update on treatment","volume":"32","author":"Wolf","year":"2013","journal-title":"PIDJ"},{"key":"10.1016\/j.jinf.2015.04.029_bib24","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/S1473-3099(13)70266-4","article-title":"Management of infections related to totally implantable venous-access ports: challenges and perspectives","volume":"14","author":"Lebeaux","year":"2014","journal-title":"Lancet Infect Dis"},{"issue":"3","key":"10.1016\/j.jinf.2015.04.029_bib25","doi-asserted-by":"crossref","first-page":"163","DOI":"10.3109\/07853890.2013.878513","article-title":"Central line-associated bloodstream infections caused by Staphylococcus aureus in cancer patients: clinical outcome and management","volume":"46","author":"El Zakhem","year":"2014","journal-title":"Ann Med"},{"key":"10.1016\/j.jinf.2015.04.029_bib26","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1086\/427806","article-title":"Risk factors for hematogenous complications of intravascular catheter-associated Staphylococcus aureus bacteremia","volume":"40","author":"Fowler","year":"2005","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.jinf.2015.04.029_bib27","doi-asserted-by":"crossref","first-page":"1272","DOI":"10.1542\/peds.107.6.1272","article-title":"Bacteraemia, central catheters and neonates: when to pull the line","volume":"107","author":"Benjamin","year":"2001","journal-title":"Pediatrics"},{"key":"10.1016\/j.jinf.2015.04.029_bib28","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1097\/01.inf.0000128779.34716.ee","article-title":"In situ diagnosis of central venous catheter-related bloodstream infection without peripheral culture","volume":"23","author":"Franklin","year":"2004","journal-title":"Pediatr Infect Dis J"},{"issue":"1","key":"10.1016\/j.jinf.2015.04.029_bib29","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1086\/599376","article-title":"Clinical practice guidelines for the diagnosis and management of intravascular catheter-related infection: 2009 update by the Infectious Diseases Society of America","volume":"49","author":"Mermel","year":"2009","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.jinf.2015.04.029_bib30","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1128\/JCM.02414-12","article-title":"Use of universal 16S rRNA gene PCR as a diagnostic tool for venous access port-related bloodstream infection","volume":"51","author":"Guembe","year":"2013","journal-title":"J Clin Microbiol"},{"issue":"6","key":"10.1016\/j.jinf.2015.04.029_bib31","doi-asserted-by":"crossref","first-page":"2275","DOI":"10.1128\/JCM.41.6.2275-2278.2003","article-title":"Blood culture contamination: persisting problems and partial progress","volume":"41","author":"Weinstein","year":"2003","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.jinf.2015.04.029_bib32","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1097\/01.inf.0000160950.83583.7f","article-title":"Diagnosis of catheter-related bloodstream infections among pediatric oncology patients lacking a peripheral culture, using differential time to detection","volume":"24","author":"Gaur","year":"2005","journal-title":"Pediatr Infect Dis J"},{"key":"10.1016\/j.jinf.2015.04.029_bib33","doi-asserted-by":"crossref","first-page":"1402","DOI":"10.1128\/JCM.42.4.1402-1408.2004","article-title":"Use of quantitative 16S ribosomal DNA detection for diagnosis of central vascular catheter-associated bacterial infection","volume":"42","author":"Warwick","year":"2004","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.jinf.2015.04.029_bib34","first-page":"e1","article-title":"Guidelines for the prevention of intravascular catheter-related infections","volume":"51","author":"O'Grady","year":"2011","journal-title":"Clin Infect Dis"},{"issue":"7","key":"10.1016\/j.jinf.2015.04.029_bib35","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1086\/676533","article-title":"Strategies to prevent central line-associated bloodstream infections in acute care hospitals: 2014 update","volume":"35","author":"Marschall","year":"2014","journal-title":"Infect Control Epidemiol"},{"issue":"S1","key":"10.1016\/j.jinf.2015.04.029_bib36","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1016\/S0195-6701(13)60012-2","article-title":"Epic 3: national evidence-based guidelines for preventing healthcare-associated infections in NHS hospitals in England","volume":"86","author":"Loveday","year":"2014","journal-title":"J Hosp Infect"},{"key":"10.1016\/j.jinf.2015.04.029_bib37","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1213\/01.ANE.0000118101.94596.A0","article-title":"Colonization and bloodstream infection with single- versus multi-lumen central venous catheters: a quantitative systematic review","volume":"99","author":"Z\u00fcrcher","year":"2004","journal-title":"Anesth Analg"},{"key":"10.1016\/j.jinf.2015.04.029_bib38","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/j.ajic.2003.10.006","article-title":"Using maximal sterile barriers to prevent central venous catheter-related infection: a systematic evidence-based review","volume":"32","author":"Hu","year":"2004","journal-title":"Am J Infect Control"},{"issue":"4","key":"10.1016\/j.jinf.2015.04.029_bib39","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1097\/SLA.0b013e3181d48a6a","article-title":"Maximal sterile barrier precautions do not reduce catheter-related bloodstream infections in general surgery units: a multi-institutional randomised controlled trial","volume":"251","author":"Ishikawa","year":"2010","journal-title":"Ann Surg"},{"issue":"12 Suppl.","key":"10.1016\/j.jinf.2015.04.029_bib40","first-page":"55","article-title":"Guideline for hand hygiene in healthcare settings: recommendations of the Healthcare Infection Control Practices Advisory Committee and the HICPAC\/SHEA\/APIC\/IDSA Hand Hygiene Task Force","volume":"23","author":"Boyce","year":"2002","journal-title":"Infect Control Hosp Epidemiol"},{"issue":"6","key":"10.1016\/j.jinf.2015.04.029_bib41","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1016\/j.ajic.2007.10.018","article-title":"Impact of a standardized hand hygiene programme on the incidence of nosocomial infection in very low birth weight infants","volume":"36","author":"Capretti","year":"2008","journal-title":"Am J Infect Control"},{"key":"10.1016\/j.jinf.2015.04.029_bib42","doi-asserted-by":"crossref","first-page":"S18","DOI":"10.1177\/1757177409342140","article-title":"Improving standards of aseptic practice through an ANTT trust-wide implementation process: a matter of prioritisation and care","volume":"10","author":"Rowley","year":"2009","journal-title":"J Infect Prev"},{"key":"10.1016\/j.jinf.2015.04.029_bib43","doi-asserted-by":"crossref","first-page":"792","DOI":"10.7326\/0003-4819-136-11-200206040-00007","article-title":"Chlorhexidine compared with povidone-iodine solution for vascular catheter site care: a meta-analysis","volume":"136","author":"Chaiyakunapruk","year":"2002","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.jinf.2015.04.029_bib44","doi-asserted-by":"crossref","first-page":"1818","DOI":"10.1097\/00003246-199611000-00010","article-title":"Prospective, randomized trial of two antiseptic solutions for prevention of central venous or arterial catheter colonization and infection in intensive care unit patients","volume":"24","author":"Mimoz","year":"1996","journal-title":"Crit Care Med"},{"key":"10.1016\/j.jinf.2015.04.029_bib45","doi-asserted-by":"crossref","first-page":"e44277","DOI":"10.1371\/journal.pone.0044277","article-title":"The forgotten role of alcohol: a systematic review and meta-analysis of the clinical efficacy and perceived role of chlorhexidine in skin antisepsis","volume":"7","author":"Maiwald","year":"2012","journal-title":"PLoS One"},{"issue":"6","key":"10.1016\/j.jinf.2015.04.029_bib46","doi-asserted-by":"crossref","first-page":"1431","DOI":"10.1542\/peds.107.6.1431","article-title":"A randomised trial comparing povdone-iodine to a chlorhexidine gluonate impregnated dressing for prevention of central venous catheter infections in neonates","volume":"107","author":"Garland","year":"2001","journal-title":"Pediatrics"},{"key":"10.1016\/j.jinf.2015.04.029_bib47","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.jhin.2005.02.002","article-title":"Prospective evaluation of a multi-factorial prevention strategy on the impact of nosocomial infection in very low birth-weight infants","volume":"61","author":"Anderson","year":"2005","journal-title":"J Hosp Infect"},{"key":"10.1016\/j.jinf.2015.04.029_bib48","article-title":"Optimal timing for intravascular administration set replacement","volume":"9","author":"Ullman","year":"2013","journal-title":"Cochrane Database Syst Rev"},{"issue":"8","key":"10.1016\/j.jinf.2015.04.029_bib49","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1016\/j.ajic.2009.03.014","article-title":"A fall in bloodstream infections followed a change in 2% chlorhexidine in 70% isopropanol for catheter connection antisepsis: a pediatric single center before\/after study on a hemopoietic stem cell transplant ward","volume":"37","author":"Soothill","year":"2009","journal-title":"Am J Infect Control"},{"issue":"8","key":"10.1016\/j.jinf.2015.04.029_bib50","doi-asserted-by":"crossref","first-page":"596","DOI":"10.7326\/0003-4819-148-8-200804150-00004","article-title":"Meta-analysis: antibiotics for prophylaxis against hemodialysis catheter-related infections","volume":"148","author":"James","year":"2008","journal-title":"Ann Intern Med"},{"issue":"8","key":"10.1016\/j.jinf.2015.04.029_bib51","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1001\/archpedi.160.8.832","article-title":"Impact of staffing on bloodstream infections in the neonatal intensive care unit","volume":"160","author":"Cimiotti","year":"2006","journal-title":"Arch Pediatr Adolesc Med"},{"key":"10.1016\/j.jinf.2015.04.029_bib52","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1086\/664496","article-title":"The efficacy of daily bathing with chlorhexidine for reducing healthcare associated bloodstream infections: a meta-analysis","volume":"33","author":"O'Horo","year":"2012","journal-title":"Infect Control Hosp Epidemiol"},{"issue":"2","key":"10.1016\/j.jinf.2015.04.029_bib53","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1086\/674862","article-title":"Chlorhexidine bathing in a tertiary care neonatal intensive care unit: Impact on central line-associated bloodstream infections","volume":"35","author":"Quach","year":"2014","journal-title":"Infect Control Hosp Epidemiol"},{"key":"10.1016\/j.jinf.2015.04.029_bib54","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1093\/jac\/dkl234","article-title":"Use of chlorhexidine-impregnated dressing to prevent vascular and epidural catheter colonization and infection: a meta-analysis","volume":"58","author":"Ho","year":"2006","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.jinf.2015.04.029_bib55","first-page":"CD007878","article-title":"Catheter impregnation, coating or bonding for reducing central venous catheter-related infections in adults","volume":"6","author":"Lai","year":"2013","journal-title":"Cochrane Database Syst Rev."},{"key":"10.1016\/j.jinf.2015.04.029_bib56","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1097\/INF.0b013e318123e8bf","article-title":"Observational trial of antibiotic-coated central venous catheters in critically ill pediatric patients","volume":"26","author":"Chelliah","year":"2007","journal-title":"Pediatr Infect Dis J"},{"issue":"7589","key":"10.1016\/j.jinf.2015.04.029_bib57","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1136\/bmj.39064.457025.DE","article-title":"Reducation of bloodstream infections associated with catheters in paediatric intensive care unit: stepwise approach","volume":"334","author":"Bhutta","year":"2007","journal-title":"BMJ"},{"issue":"4","key":"10.1016\/j.jinf.2015.04.029_bib58","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1097\/BCR.0b013e31823c4cd5","article-title":"Incidence of catheter-associated bloodstream infection after introduction of minocycline and rifampicin antimicrobial-coated catheters in a pediatric burn population","volume":"33","author":"Weber","year":"2012","journal-title":"J Burn Care Res"},{"issue":"1","key":"10.1016\/j.jinf.2015.04.029_bib59","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1016\/j.ajic.2012.05.030","article-title":"Continuous passive disinfection of catheter hubs prevents contamination and bloodstream infection","volume":"41","author":"Wright","year":"2013","journal-title":"Am J Infect Control"},{"issue":"1","key":"10.1016\/j.jinf.2015.04.029_bib60","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.earlhumdev.2012.07.003","article-title":"Reduction of catheter-related bloodstream infections in preterm infants by the use of catheters with the AgION antimicrobial system","volume":"89","author":"Bertinin","year":"2013","journal-title":"Early Hum Dev"},{"issue":"5","key":"10.1016\/j.jinf.2015.04.029_bib61","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1046\/j.1469-0691.2002.00388.x","article-title":"The antibiotic-lock technique for therapy of \u2018highly needed\u2019 infected catheters","volume":"8","author":"Carratala","year":"2002","journal-title":"Clin Microbiol Infect"},{"key":"10.1016\/j.jinf.2015.04.029_bib62","first-page":"1","article-title":"Antibiotic and other lock treatments for tunnelled central venous catheter-related infections in childen with cancer","volume":"6","author":"Schoot","year":"2013","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.jinf.2015.04.029_bib63","doi-asserted-by":"crossref","first-page":"1799","DOI":"10.2215\/CJN.01270210","article-title":"Emergence of gentamicin-resistant bacteraemia in hemodialysis patients receiving gentamicin lock catheter prophylaxis","volume":"10","author":"Landry","year":"2010","journal-title":"Clin J Am Soc Nephrol"},{"issue":"12","key":"10.1016\/j.jinf.2015.04.029_bib64","doi-asserted-by":"crossref","first-page":"1741","DOI":"10.1093\/cid\/ciu671","article-title":"Antimicrobial lock solutions as a method to prevent central line-associated bloodstream infections: a meta-analysis of randomised controlled trials","volume":"59","author":"Zachariodakis","year":"2014","journal-title":"Clin Infect Dis"},{"issue":"11","key":"10.1016\/j.jinf.2015.04.029_bib65","doi-asserted-by":"crossref","first-page":"79417","DOI":"10.1371\/journal.pone.0079417","article-title":"Taurolidine lock solutions for the prevention of catheter-related bloodstream infections: a systematic review and meta-analysis of randomized controlled trials","volume":"8","author":"Liu","year":"2013","journal-title":"PLoS ONE"},{"key":"10.1016\/j.jinf.2015.04.029_bib66","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1186\/1471-2369-10-23","article-title":"Rationale and design of the HEALTHY-CATH trial: a randomised controlled trial of Heparin versus EthAnol Lock THerapY for the prevention of Catheter Associated infecTion in Haemodialysis patients","volume":"10","author":"Broom","year":"2009","journal-title":"BMC Nephrol"},{"key":"10.1016\/j.jinf.2015.04.029_bib67","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1093\/jac\/dkn284","article-title":"A prospective double-blind randomized trial comparing intraluminal ethanol with heparinised saline for the prevention of catheter-associated bloodstream infection in immunosuppressed haematology patients","volume":"62","author":"Sanders","year":"2008","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.jinf.2015.04.029_bib68","doi-asserted-by":"crossref","first-page":"e10840","DOI":"10.1371\/journal.pone.0010840","article-title":"Prevention of catheter-related bacteramia with a daily ethanol lock in patients with tunnelled catheters. A randomised, placbo-controlled trial","volume":"5","author":"Slobbe","year":"2010","journal-title":"PLoS One"},{"key":"10.1016\/j.jinf.2015.04.029_bib69","series-title":"Ethanol lock therapy for the prevention of catheter-related bloodstream infections in paediatric patients. Presented at the 48th annual meeting of IDSA. Vancouver, BC, Canada","author":"Martin","year":"2010"},{"key":"10.1016\/j.jinf.2015.04.029_bib70","doi-asserted-by":"crossref","first-page":"1961","DOI":"10.1016\/j.jpedsurg.2010.05.014","article-title":"Preliminary results of a phase I trial of prophylactic ethanol-lock administration to prevent mediport catheter-related bloodstream infections","volume":"4","author":"Kayton","year":"2010","journal-title":"J Pediatr Surg"},{"key":"10.1016\/j.jinf.2015.04.029_bib71","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1177\/0148607107031004302","article-title":"Use of ethanol lock therapy to reduce the incidence of catheter-related bloodstream infections in home parenteral nutrition patients","volume":"31","author":"Opilla","year":"2007","journal-title":"JPEN J Parenter Enteral Nutr"},{"key":"10.1016\/j.jinf.2015.04.029_bib72","doi-asserted-by":"crossref","first-page":"342","DOI":"10.5414\/CNP65342","article-title":"Effect of ethanol\/trisodium citrate lock on the mechanical properties of haemodialysis catheters","volume":"65","author":"Bell","year":"2006","journal-title":"Clin Nephrol"},{"key":"10.1016\/j.jinf.2015.04.029_bib73","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1002\/pbc.24249","article-title":"Review: ethanol lock therapy in pediatric hematology and oncology","volume":"60","author":"Wolf","year":"2013","journal-title":"Pediatr Blood Cancer"},{"key":"10.1016\/j.jinf.2015.04.029_bib74","first-page":"CD003295","article-title":"Prophylactic antibiotics for preventing Gram positive infections associated with long-term central venous catheters in oncology patients","volume":"11","author":"van\u00a0de\u00a0Wetering","year":"2013","journal-title":"Cochrane Database Syst Rev."},{"key":"10.1016\/j.jinf.2015.04.029_bib75","doi-asserted-by":"crossref","DOI":"10.3109\/01421591003596600","article-title":"What features of educational interventions lead to competence in aseptic insertion and maintenance of CV catheters in acute care? BEME Guide No. 15","volume":"32","author":"Cherry","year":"2010","journal-title":"Med Teach"},{"key":"10.1016\/j.jinf.2015.04.029_bib76","article-title":"Prevention of central venous catheter-related infection in the neonatal unit: a literature review","author":"Taylor","year":"2014","journal-title":"J Materno-Fetal Neonatal Med"},{"key":"10.1016\/j.jinf.2015.04.029_bib77","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1542\/peds.2009-1382","article-title":"Decreasing PICU catheter-associated bloodstream infections: NACHRI's quality transformation efforts","volume":"125","author":"Miller","year":"2010","journal-title":"Pediatrics"},{"issue":"6","key":"10.1016\/j.jinf.2015.04.029_bib78","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1016\/j.ijnurstu.2012.02.009","article-title":"Effectiveness of non-pharmacological interventions for the prevention of bloodstream infections in infants admitted to a neonatal intensive care unit: a systematic review","volume":"50","author":"Helder","year":"2013","journal-title":"Int J Nurs Stud"},{"key":"10.1016\/j.jinf.2015.04.029_bib79","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1038\/jp.2009.172","article-title":"A statewide quality improvement collaborative to reduce neonatal central line-associated blood stream infections","volume":"30","author":"Wirtschafter","year":"2010","journal-title":"J Perinatol"},{"key":"10.1016\/j.jinf.2015.04.029_bib80","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1038\/jp.2009.18","article-title":"Development of a statewide collaborative to decrease NICU central line-associated bloodstream infections","volume":"29","author":"Schulman","year":"2009","journal-title":"J Perinatol"},{"key":"10.1016\/j.jinf.2015.04.029_bib81","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1086\/650448","article-title":"A quality improvement initiative to reduce central line associated bloodstream infections in a neonatal intensive care unit","volume":"31","author":"Bizzarro","year":"2010","journal-title":"Infect Control Hosp Epidemiol"},{"issue":"Suppl. 2","key":"10.1016\/j.jinf.2015.04.029_bib82","doi-asserted-by":"crossref","first-page":"S114","DOI":"10.1086\/320184","volume":"32","author":"Diekema","year":"2001","journal-title":"Clin Infect Dis"},{"issue":"3","key":"10.1016\/j.jinf.2015.04.029_bib83","doi-asserted-by":"crossref","DOI":"10.2165\/00003495-200767030-00003","article-title":"The epidemiology, pathogenesis and treatment of Pseudomonas aeruginosa infections","volume":"67","author":"Driscoll","year":"2007","journal-title":"Drugs"},{"issue":"3","key":"10.1016\/j.jinf.2015.04.029_bib84","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1128\/CMR.05041-11","article-title":"Combination therapy for treatment of infections with gram-negative bacteria","volume":"25","author":"Tamma","year":"2012","journal-title":"Clin Microbiol Rev"},{"issue":"5","key":"10.1016\/j.jinf.2015.04.029_bib85","doi-asserted-by":"crossref","first-page":"e1148","DOI":"10.1542\/peds.2013-3363","article-title":"Empiric combination therapy for gram-negative bacteremia","volume":"133","author":"Sick","year":"2014","journal-title":"Paediatrics"},{"key":"10.1016\/j.jinf.2015.04.029_bib86","doi-asserted-by":"crossref","first-page":"1651","DOI":"10.1097\/CCM.0b013e3181e96b91","article-title":"A survival benefit of combination antibiotic therapy for serious infections associated with sepsis and septic shock is contingent only on the risk of death: a meta-analytic\/meta-regression study","volume":"38","author":"Kumar","year":"2010","journal-title":"Crit Care Med"},{"issue":"6","key":"10.1016\/j.jinf.2015.04.029_bib87","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1007\/s00134-004-2212-x","article-title":"Watchful waiting versus immediate catheter removal in ICU patients with suspected catheter-related infection: a randomized trial","volume":"30","author":"Rijnders","year":"2004","journal-title":"Intensive Care Med"},{"issue":"3","key":"10.1016\/j.jinf.2015.04.029_bib88","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1086\/653935","article-title":"Early removal of central venous catheter in patients with candidemia does not improve outcome: analysis of 842 patients from 2 randomized clinical trials","volume":"51","author":"Nucci","year":"2010","journal-title":"Clin Infect Dis"},{"issue":"8","key":"10.1016\/j.jinf.2015.04.029_bib89","doi-asserted-by":"crossref","first-page":"1110","DOI":"10.1093\/cid\/cis021","article-title":"Impact of treatment strategy on outcomes in patients with candidemia and other forms of invasive candidiasis: a patient level quantitative review of randomized trials","volume":"54","author":"Andes","year":"2012","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.jinf.2015.04.029_bib90","doi-asserted-by":"crossref","first-page":"e269","DOI":"10.1542\/peds.111.3.e269","article-title":"Central venous catheter removal versus in situ treatment in neonates with Enterobacteriaceae bacteraemia","volume":"111","author":"Nazemi","year":"2003","journal-title":"Pediatrics"},{"key":"10.1016\/j.jinf.2015.04.029_bib91","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1097\/01.inf.0000128781.77600.6f","article-title":"Risk factors for disseminated candidiasis in children with candidemia","volume":"23","author":"Zaoutis","year":"2004","journal-title":"Pediatr Infect Dis J"},{"key":"10.1016\/j.jinf.2015.04.029_bib92","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1097\/00006454-199005000-00002","article-title":"Candidaemia in children with CVC: role of catheter removal and amphotericin B therapy","volume":"9","author":"Data","year":"1990","journal-title":"Pediatr Infect Dis J"},{"issue":"5","key":"10.1016\/j.jinf.2015.04.029_bib93","doi-asserted-by":"crossref","first-page":"E63","DOI":"10.1542\/peds.106.5.e63","article-title":"Should central venous catheters be removed as soon as candidaemia is detected in neonates?","volume":"106","author":"Karlowicz","year":"2000","journal-title":"Pediatrics"},{"key":"10.1016\/j.jinf.2015.04.029_bib94","first-page":"215","article-title":"Impact of central venous catheter removal on recurrence of catheter-related coagulase-negative staphylococcal bacteraemia","volume":"13","author":"Raad","year":"1992","journal-title":"Infect Control Hosp Epidemiol"},{"issue":"8","key":"10.1016\/j.jinf.2015.04.029_bib95","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.1086\/605694","article-title":"Management of the catheter in documented catheter-related coagulase-negative staphylococcal bacteremia: remove or retain?","volume":"49","author":"Raad","year":"2009","journal-title":"Clin Infect Dis"},{"issue":"1","key":"10.1016\/j.jinf.2015.04.029_bib96","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1097\/00006454-200201000-00005","article-title":"Central venous catheter removal versus in situ treatment in neonates with coagulase-negative staphylococcal bacteraemia","volume":"21","author":"Karlowicz","year":"2002","journal-title":"Pediatr Infect Dis J"},{"key":"10.1016\/j.jinf.2015.04.029_bib97","doi-asserted-by":"crossref","first-page":"1417","DOI":"10.1097\/00003246-199708000-00033","article-title":"Central venous catheter replacement strategies: a systematic review of the literature","volume":"25","author":"Cook","year":"1997","journal-title":"Crit Care Med"},{"issue":"1","key":"10.1016\/j.jinf.2015.04.029_bib98","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1093\/jac\/dkh488","article-title":"Treatment of long-term intravascular catheter-related bacteraemia with antibiotic lock: randomised, placebo controlled trial","volume":"55","author":"Rijinders","year":"2005","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.jinf.2015.04.029_bib99","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1093\/jac\/dkl318","article-title":"Treatment of long-term intravascular catheter-related bacteraemia with antibiotic lock therapy","volume":"58","author":"Fort\u00fan","year":"2006","journal-title":"J Antimicrob Chemother"},{"issue":"8","key":"10.1016\/j.jinf.2015.04.029_bib100","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1097\/INF.0b013e318170b68b","article-title":"Treatment of central venous catheter fungal infection using liposomal amphotericin-B lock therapy","volume":"27","author":"Buckler","year":"2008","journal-title":"Pediatr Infect Dis J"},{"key":"10.1016\/j.jinf.2015.04.029_bib101","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1016\/j.ijantimicag.2004.06.006","article-title":"Taurolidine is effective in the treatment of central venous catheter-related bloodstream infections in cancer patients","volume":"24","author":"Koldehoff","year":"2004","journal-title":"Int J Antimicrob Agents"},{"issue":"3","key":"10.1016\/j.jinf.2015.04.029_bib102","doi-asserted-by":"crossref","first-page":"244","DOI":"10.5301\/JVA.2011.6265","article-title":"Treatment of long-term catheter-related bloodstream infections with a taurolidine block: a single cancer center experience","volume":"12","author":"Haag","year":"2011","journal-title":"J Vasc Access"},{"key":"10.1016\/j.jinf.2015.04.029_bib103","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1097\/00043426-200308000-00006","article-title":"Ethanol-lock technique in the treatment of bloodstream infections in pediatric oncology patients with broviac catheter","volume":"25","author":"Dannenberg","year":"2003","journal-title":"J Pediatr Hematol Oncol"},{"key":"10.1016\/j.jinf.2015.04.029_bib104","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1177\/0009922811409568","article-title":"Short-dwell ethanol lock therapy in children is associated with increased clearance of central-line associated bloodstream infections","volume":"50","author":"McGrath","year":"2011","journal-title":"Clin Pediatr"},{"issue":"10","key":"10.1016\/j.jinf.2015.04.029_bib105","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1001\/archpedi.160.10.1049","article-title":"Ethanol-lock technique for persistent bacteremia of long-term intravascular devices in pediatric patients","volume":"160","author":"Onland","year":"2006","journal-title":"Arch Pediatr Adolesc Med"},{"issue":"3","key":"10.1016\/j.jinf.2015.04.029_bib106","first-page":"289","article-title":"Echinocandin and ethanol lock therapy treatment of fungal catheter infections","volume":"32","author":"Pieroni","year":"2013","journal-title":"PIDJ"},{"key":"10.1016\/j.jinf.2015.04.029_bib107","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1097\/INF.0b013e31822c84a4","article-title":"Ethanol locks therapy for resolution of fungal catheter infections","volume":"30","author":"Blackwood","year":"2011","journal-title":"Pediatr Infect Dis J"},{"issue":"5","key":"10.1016\/j.jinf.2015.04.029_bib108","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1080\/00365540701756953","article-title":"Ethanol lock therapy to treat tunnelled central venous catheter-associated blood stream infections: results from a prospective trial","volume":"40","author":"Broom","year":"2008","journal-title":"Scand J Infect Dis"},{"key":"10.1016\/j.jinf.2015.04.029_bib109","doi-asserted-by":"crossref","first-page":"e64","DOI":"10.1097\/MPH.0b013e3181f6933d","article-title":"Hydrochloric acid treatment of tunnelled central venous catheter infections in children with cancer","volume":"33","author":"Larsen","year":"2011","journal-title":"J Pediatr Hematol Oncol"},{"issue":"1","key":"10.1016\/j.jinf.2015.04.029_bib110","doi-asserted-by":"crossref","first-page":"38","DOI":"10.3109\/00365548.2012.708941","article-title":"Impact of hydrochloric acid instillation on salvage of infected central venous catheters in children with acute lymphoblastic leukaemia","volume":"45","author":"Madsen","year":"2013","journal-title":"Scand J Infect Dis"},{"issue":"3","key":"10.1016\/j.jinf.2015.04.029_bib111","first-page":"195","article-title":"Factitious disease: clinical lessons from case studies at Baylor University Medical Center","volume":"19","author":"Savino","year":"2006","journal-title":"Proc (Bayl Univ Med Cent)"},{"key":"10.1016\/j.jinf.2015.04.029_bib112","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1016\/S1473-3099(07)70235-9","article-title":"Intravascular catheter-related infections: advances in diagnosis, prevention, and management","volume":"7","author":"Raad","year":"2007","journal-title":"Lancet Infect Dis"},{"key":"10.1016\/j.jinf.2015.04.029_bib113","doi-asserted-by":"crossref","first-page":"1082","DOI":"10.1136\/adc.2009.173856","article-title":"Portacaths are safe for long-term regular blood transfusion in children with sickle cell anaemia","volume":"96","author":"Bartram","year":"2011","journal-title":"Arch Dis Child"},{"issue":"4","key":"10.1016\/j.jinf.2015.04.029_bib114","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/j.amjmed.2014.01.001","article-title":"PICC-associated bloodstream infections: prevalence, patterns, and predictors","volume":"127","author":"Chopra","year":"2014","journal-title":"Am J Med"},{"key":"10.1016\/j.jinf.2015.04.029_bib116","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1016\/j.clon.2007.04.003","article-title":"A comparison of Hickman line and Port-a-Cath-associated complications in patients with solid tumours undergoing chemotherapy","volume":"19","author":"Ng","year":"2007","journal-title":"Clin Oncol (R Coll Radiol)"},{"issue":"4","key":"10.1016\/j.jinf.2015.04.029_bib117","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1016\/j.jhin.2012.01.003","article-title":"Randomized controlled trial of taurolidine citrate versus heparin as catheter lock solution in paediatric patients with haematological malignancies","volume":"80","author":"D\u00fcmichen","year":"2012","journal-title":"J Hosp Infect"},{"key":"10.1016\/j.jinf.2015.04.029_bib118","doi-asserted-by":"crossref","first-page":"1291","DOI":"10.1002\/pbc.24482","article-title":"Central venous catheters and catheter locks in children with cancer: a prospective randomised trial of taurolidine versus heparin","volume":"60","author":"Handrup","year":"2013","journal-title":"Pediatr Blood Cancer"},{"key":"10.1016\/j.jinf.2015.04.029_bib119","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1097\/MPG.0b013e31825bb0ae","article-title":"Significant reduction in central venous catheter-related bloodstream infections in children on HPN after starting treatment with Taurolidine line lock","volume":"55","author":"Chu","year":"2012","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"10.1016\/j.jinf.2015.04.029_bib120","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1186\/1471-2334-8-102","article-title":"Taurolidine-citrate lock solution (TauroLock) significantly reduces CVAD-associated Gram-positive infections in pediatric cancer patients","volume":"8","author":"Simon","year":"2008","journal-title":"BMC Infect Dis"},{"key":"10.1016\/j.jinf.2015.04.029_bib121","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1159\/000331262","article-title":"Anti-infective locks for the treatment of central line-associated bloodstream infection: a systematic review and meta-analysis","volume":"34","author":"O'Horo","year":"2011","journal-title":"Am J Nephrol"},{"issue":"4","key":"10.1016\/j.jinf.2015.04.029_bib122","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1086\/501893","article-title":"Guidelines for the management of intravascular catheter-related infections","volume":"22","author":"Mermel","year":"2001","journal-title":"Infect Control Hosp Epidemiol"},{"issue":"10","key":"10.1016\/j.jinf.2015.04.029_bib123","doi-asserted-by":"crossref","first-page":"1811","DOI":"10.1002\/pbc.25101","article-title":"No evidence of benefit from antibiotic lock therapy in pediatric oncology patients with central line-related bloodstream infection: results of a retrospective matched cohort study and review of the literature","volume":"61","author":"Wolf","year":"2014","journal-title":"Pediatr Blood Cancer"},{"issue":"2","key":"10.1016\/j.jinf.2015.04.029_bib124","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1177\/0148607102026002104","article-title":"Local antibiotic lock for the treatment of infections related to central catheters in parenteral nutrition in children","volume":"26","author":"Cuntz","year":"2002","journal-title":"JPEN J Parenter Enteral Nutr"},{"issue":"3","key":"10.1016\/j.jinf.2015.04.029_bib125","first-page":"127","article-title":"The antibiotic-lock therapy in oncoematology pediatric unit","volume":"24","author":"Bernardi","year":"2005","journal-title":"Assist Inferm Ric"},{"key":"10.1016\/j.jinf.2015.04.029_bib126","doi-asserted-by":"crossref","first-page":"930","DOI":"10.1097\/00006454-199410000-00015","article-title":"Preliminary results treating persistent central venous catheter infections with the antibiotic lock technique in pediatric patients","volume":"13","author":"Johnson","year":"1994","journal-title":"Pediatr Infect Dis J"},{"issue":"8","key":"10.1016\/j.jinf.2015.04.029_bib127","doi-asserted-by":"crossref","first-page":"1452","DOI":"10.1097\/00003246-199808000-00038","article-title":"Tunneling short-term central venous catheters to prevent catheter-related infection: a meta-analysis of randomized, controlled trials","volume":"26","author":"Randolph","year":"1998","journal-title":"Crit Care Med"}],"container-title":["Journal of Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S016344531500122X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S016344531500122X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T21:21:26Z","timestamp":1759008086000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S016344531500122X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,6]]},"references-count":126,"alternative-id":["S016344531500122X"],"URL":"https:\/\/doi.org\/10.1016\/j.jinf.2015.04.029","relation":{},"ISSN":["0163-4453"],"issn-type":[{"value":"0163-4453","type":"print"}],"subject":[],"published":{"date-parts":[[2015,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The prevention, diagnosis and management of central venous line infections in children","name":"articletitle","label":"Article Title"},{"value":"Journal of Infection","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jinf.2015.04.029","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 The British Infection Association. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}