{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T22:21:04Z","timestamp":1790634064537,"version":"4.1.0"},"reference-count":73,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2018,9,1]],"date-time":"2018-09-01T00:00:00Z","timestamp":1535760000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,9,1]],"date-time":"2018-09-01T00:00:00Z","timestamp":1535760000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","journalofinfection.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Infection"],"published-print":{"date-parts":[[2018,9]]},"DOI":"10.1016\/j.jinf.2018.07.006","type":"journal-article","created":{"date-parts":[[2018,7,24]],"date-time":"2018-07-24T10:53:31Z","timestamp":1532429611000},"page":"166-170","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":113,"title":["Burkholderia cepacia complex infections: More complex than the bacterium name suggest"],"prefix":"10.1016","volume":"77","author":[{"given":"Maroun M.","family":"Sfeir","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.jinf.2018.07.006_bib0001","first-page":"115","article-title":"Sour skin, a bacterial rot of onion bulbs","volume":"40","author":"Burkholder","year":"1950","journal-title":"Phytopathology"},{"issue":"12","key":"10.1016\/j.jinf.2018.07.006_bib0002","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1056\/NEJM199503233321213","article-title":"Burkholderia cepacia in cystic-fibrosis","volume":"332","author":"Mahenthiralingam","year":"1995","journal-title":"New Engl J Med"},{"issue":"6","key":"10.1016\/j.jinf.2018.07.006_bib0003","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/femspd\/ftx076","article-title":"Detection of misidentifications of species from the Burkholderia cepacia complex and description of a new member, the soil bacterium Burkholderia catarinensis sp nov","volume":"75","author":"Bach","year":"2017","journal-title":"Pathog Dis"},{"issue":"11","key":"10.1016\/j.jinf.2018.07.006_bib0004","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1099\/0022-1317-51-11-937","article-title":"Evaluation of species-specific recA-based PCR tests for genomovar level identification within the Burkholderia cepacia complex","volume":"51","author":"Vermis","year":"2002","journal-title":"J Med Microbiol"},{"issue":"8","key":"10.1016\/j.jinf.2018.07.006_bib0005","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1136\/thx.2007.089458","article-title":"Clinical outcome following lung transplantation in patients with cystic fibrosis colonised with Burkholderia cepacia complex: results from two French centres","volume":"63","author":"Boussaud","year":"2008","journal-title":"Thorax"},{"issue":"9","key":"10.1016\/j.jinf.2018.07.006_bib0006","doi-asserted-by":"crossref","first-page":"1243","DOI":"10.1086\/383313","article-title":"Virulence associated with outbreak-related strains of Burkholderia cepacia complex among a cohort of patients with bacteremia","volume":"38","author":"Woods","year":"2004","journal-title":"Clin Infect Dis"},{"issue":"11","key":"10.1016\/j.jinf.2018.07.006_bib0007","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0143472","article-title":"Whole-genome sequencing of three clonal clinical isolates of B. cenocepacia from a patient with cystic fibrosis","volume":"10","author":"Miller","year":"2015","journal-title":"PLoS One"},{"issue":"4","key":"10.1016\/j.jinf.2018.07.006_bib0008","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1164\/rccm.200503-344OC","article-title":"Impact of Burkholderia dolosa on lung function and survival in cystic fibrosis","volume":"173","author":"Kalish","year":"2006","journal-title":"Am J Respir Crit Care Med"},{"issue":"2","key":"10.1016\/j.jinf.2018.07.006_bib0009","first-page":"123","article-title":"Cepacia-like syndrome caused by Burkholderia multivorans","volume":"14","author":"Zahariadis","year":"2003","journal-title":"Can J Infect Dis (Journal Canadien des Maladies Infectieuses)"},{"issue":"2","key":"10.1016\/j.jinf.2018.07.006_bib0010","doi-asserted-by":"crossref","first-page":"221","DOI":"10.3201\/eid0402.980209","article-title":"Agricultural use of Burkholderia (Pseudomonas) cepacia: a threat to human health?","volume":"4","author":"Holmes","year":"1998","journal-title":"Emerg Infect Dis"},{"issue":"10","key":"10.1016\/j.jinf.2018.07.006_bib0011","doi-asserted-by":"crossref","first-page":"4337","DOI":"10.1128\/IAI.00259-09","article-title":"Virulence and cellular interactions of Burkholderia multivorans in chronic granulomatous disease","volume":"77","author":"Zelazny","year":"2009","journal-title":"Infect Immun"},{"key":"10.1016\/j.jinf.2018.07.006_bib0012","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1086\/676882","article-title":"Infection prevention and control guideline for cystic fibrosis: 2013 update","volume":"35","author":"Saiman","year":"2014","journal-title":"Infect Cont Hosp Ep"},{"key":"10.1016\/j.jinf.2018.07.006_bib0013","unstructured":"B M. Cystic Fibrosis Foundation Patient Registry 2016(Annual Data Report 2016)."},{"issue":"2","key":"10.1016\/j.jinf.2018.07.006_bib0014","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1378\/chest.15-0676","article-title":"Changing epidemiology of the respiratory bacteriology of patients with cystic fibrosis","volume":"149","author":"Salsgiver","year":"2016","journal-title":"Chest"},{"issue":"8","key":"10.1016\/j.jinf.2018.07.006_bib0015","doi-asserted-by":"crossref","first-page":"804","DOI":"10.1086\/660876","article-title":"An outbreak of Burkholderia cepacia complex associated with intrinsically contaminated nasal spray","volume":"32","author":"Dolan","year":"2011","journal-title":"Infect Control Hosp Epidemiol"},{"key":"10.1016\/j.jinf.2018.07.006_bib0016","first-page":"796","article-title":"Nosocomial Burkholderia cepacia infections associated with exposure to sublingual probes \u2013 Texas","volume":"53","author":"Metcalf","year":"2004"},{"key":"10.1016\/j.jinf.2018.07.006_bib0017","series-title":"Burkholderia cepacia contamination","year":"2017"},{"issue":"49","key":"10.1016\/j.jinf.2018.07.006_bib0018","doi-asserted-by":"crossref","first-page":"23","DOI":"10.2807\/1560-7917.ES.2017.22.49.17-00213","article-title":"Burkholderia stabilis outbreak associated with contaminated commercially-available washing gloves, Switzerland, May 2015 to August 2016","volume":"22","author":"Sommerstein","year":"2017","journal-title":"Eurosurveillance"},{"issue":"3","key":"10.1016\/j.jinf.2018.07.006_bib0019","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/j.jhin.2017.09.012","article-title":"Outbreak of Burkholderia cepacia pseudobacteraemia caused by intrinsically contaminated commercial 0.5% chlorhexidine solution in neonatal intensive care units","volume":"98","author":"Song","year":"2017","journal-title":"J Hosp Infect"},{"issue":"5","key":"10.1016\/j.jinf.2018.07.006_bib0020","doi-asserted-by":"crossref","first-page":"2113","DOI":"10.1007\/s11274-012-1016-3","article-title":"Diversity of potential pathogenicity and biofilm formation among Burkholderia cepacia complex water, clinical, and agricultural isolates in China","volume":"28","author":"Ibrahim","year":"2012","journal-title":"World J Microb Biot"},{"issue":"5","key":"10.1016\/j.jinf.2018.07.006_bib0021","doi-asserted-by":"crossref","first-page":"1760","DOI":"10.1128\/aem.58.5.1760-1763.1992","article-title":"Pseudomonas-cepacia suppression of sunflower wilt fungus and role of antifungal compounds in controlling the disease","volume":"58","author":"Mcloughlin","year":"1992","journal-title":"Appl Environ Microb"},{"issue":"3","key":"10.1016\/j.jinf.2018.07.006_bib0022","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/0038-0717(95)00147-6","article-title":"Population density of the biocontrol agent Burkholderia cepacia AMMDR1 on four pea cultivars","volume":"28","author":"King","year":"1996","journal-title":"Soil Biol Biochem"},{"issue":"2","key":"10.1016\/j.jinf.2018.07.006_bib0023","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/0378-1119(88)90043-1","article-title":"Cloning, physical mapping and expression of chromosomal genes specifying degradation of the herbicide 2,4,5-T by Pseudomonas-cepacia AC1100","volume":"71","author":"Sangodkar","year":"1988","journal-title":"Gene"},{"issue":"3","key":"10.1016\/j.jinf.2018.07.006_bib0024","doi-asserted-by":"crossref","first-page":"458","DOI":"10.3201\/eid1303.060403","article-title":"Environmental Burkholderia cepacia complex isolates in human infections","volume":"13","author":"Baldwin","year":"2007","journal-title":"Emerg Infect Dis"},{"issue":"7724","key":"10.1016\/j.jinf.2018.07.006_bib0025","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1016\/S0140-6736(71)92150-7","article-title":"Foot lesions associated with Pseudomonas cepacia","volume":"2","author":"Taplin","year":"1971","journal-title":"Lancet"},{"issue":"2","key":"10.1016\/j.jinf.2018.07.006_bib0026","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1016\/S0022-3476(84)80993-2","article-title":"Pseudomonas cepacia infection in cystic fibrosis: an emerging problem","volume":"104","author":"Isles","year":"1984","journal-title":"J Pediatr"},{"key":"10.1016\/j.jinf.2018.07.006_bib0027","article-title":"Cepacia syndrome in a non-cystic fibrosis patient","volume":"2015","author":"Hauser","year":"2015","journal-title":"Case Rep Infect Dis"},{"issue":"2","key":"10.1016\/j.jinf.2018.07.006_bib0028","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/j.jceh.2016.08.008","article-title":"Spontaneous bacterial peritonitis by Burkholderia cepacia complex: a rare, difficult to treat infection in decompensated cirrhotic patients","volume":"7","author":"Taneja","year":"2017","journal-title":"J Clin Exp Hepatol"},{"issue":"9","key":"10.1016\/j.jinf.2018.07.006_bib0029","doi-asserted-by":"crossref","first-page":"1801","DOI":"10.1097\/IAE.0b013e31820a6a03","article-title":"Burkholderia cepacia endophthalmitis: clinico-microbiologic profile and outcomes","volume":"31","author":"Sachdeva","year":"2011","journal-title":"Retina"},{"issue":"Pt 11","key":"10.1016\/j.jinf.2018.07.006_bib0030","doi-asserted-by":"crossref","first-page":"1517","DOI":"10.1099\/jmm.0.011197-0","article-title":"Burkholderia cepacia keratitis with endophthalmitis","volume":"58","author":"Ornek","year":"2009","journal-title":"J Med Microbiol"},{"issue":"5","key":"10.1016\/j.jinf.2018.07.006_bib0031","doi-asserted-by":"crossref","first-page":"e219","DOI":"10.1016\/j.jinf.2006.01.024","article-title":"Cervical necrotizing fasciitis: a novel clinical presentation of Burkholderia cepacia infection","volume":"53","author":"Marioni","year":"2006","journal-title":"J Infect"},{"issue":"2","key":"10.1016\/j.jinf.2018.07.006_bib0032","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1016\/j.jpedsurg.2011.11.003","article-title":"Prostatic abscess in a pediatric patient with chronic granulomatous disease: report of a unique case and review of the literature","volume":"47","author":"Agochukwu","year":"2012","journal-title":"J Pediatric Surg"},{"issue":"4","key":"10.1016\/j.jinf.2018.07.006_bib0033","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1007\/s00383-004-1348-7","article-title":"Intramural bladder-wall abscess: a late complication arising after a urethrocystoscopy?","volume":"21","author":"Loertzer","year":"2005","journal-title":"Pediatric Surg Int"},{"issue":"11","key":"10.1016\/j.jinf.2018.07.006_bib0034","doi-asserted-by":"crossref","first-page":"1957","DOI":"10.3201\/eid1011.040127","article-title":"Burkholderia cenocepacia vaginal infection in patient with smoldering myeloma and chronic hepatitis C","volume":"10","author":"Petrucca","year":"2004","journal-title":"Emerg Infect Dis"},{"issue":"2","key":"10.1016\/j.jinf.2018.07.006_bib0035","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/j.ajem.2004.03.012","article-title":"Urachal abscess: a cause of adult abdominal pain that cannot be ignored","volume":"23","author":"Hsu","year":"2005","journal-title":"Am J Emerg Med"},{"issue":"4","key":"10.1016\/j.jinf.2018.07.006_bib0036","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/j.jcf.2009.04.007","article-title":"Acute Burkholderia cenocepacia pyomyositis in a patient with cystic fibrosis","volume":"8","author":"El-Laboudi","year":"2009","journal-title":"J Cyst Fibros"},{"issue":"4","key":"10.1016\/j.jinf.2018.07.006_bib0037","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.1128\/JCM.37.4.1004-1007.1999","article-title":"Comparison of isolation media for recovery of Burkholderia cepacia complex from respiratory secretions of patients with cystic fibrosis","volume":"37","author":"Henry","year":"1999","journal-title":"J Clin Microbiol"},{"issue":"7","key":"10.1016\/j.jinf.2018.07.006_bib0038","doi-asserted-by":"crossref","first-page":"3917","DOI":"10.1128\/AEM.71.7.3917-3927.2005","article-title":"Development of a recA gene-based identification approach for the entire Burkholderia genus","volume":"71","author":"Payne","year":"2005","journal-title":"Appl Environ Microbiol"},{"issue":"2","key":"10.1016\/j.jinf.2018.07.006_bib0039","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/j.diagmicrobio.2013.06.011","article-title":"Performance of MALDI-ToF MS for species identification of Burkholderia cepacia complex clinical isolates","volume":"77","author":"Fehlberg","year":"2013","journal-title":"Diagn Micr Infect Dis"},{"issue":"7","key":"10.1016\/j.jinf.2018.07.006_bib0040","doi-asserted-by":"crossref","first-page":"2158","DOI":"10.1128\/JCM.37.7.2158-2164.1999","article-title":"Identification of Burkholderia spp. in the clinical microbiology laboratory: comparison of conventional and molecular methods","volume":"37","author":"van Pelt","year":"1999","journal-title":"J Clin Microbiol"},{"issue":"8","key":"10.1016\/j.jinf.2018.07.006_bib0041","doi-asserted-by":"crossref","first-page":"2607","DOI":"10.1128\/JCM.00770-09","article-title":"Expanded multilocus sequence typing for burkholderia species","volume":"47","author":"Spilker","year":"2009","journal-title":"J Clin Microbiol"},{"issue":"1","key":"10.1016\/j.jinf.2018.07.006_bib0042","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1128\/JCM.01818-07","article-title":"Elucidating global epidemiology of Burkholderia multivorans in cases of cystic fibrosis by multilocus sequence typing","volume":"46","author":"Baldwin","year":"2008","journal-title":"J Clin Microbiol"},{"issue":"1","key":"10.1016\/j.jinf.2018.07.006_bib0043","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1128\/JCM.38.1.282-285.2000","article-title":"Species-specific PCR as a tool for the identification of Burkholderia gladioli","volume":"38","author":"Whitby","year":"2000","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.jinf.2018.07.006_bib0044","series-title":"Performance standards for antimicrobial susceptibility testing","year":"2014"},{"issue":"4","key":"10.1016\/j.jinf.2018.07.006_bib0045","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1016\/j.diagmicrobio.2016.08.015","article-title":"In vitro susceptibility of Burkholderia cepacia complex isolates: comparison of disk diffusion, Etest (R), agar dilution, and broth microdilution methods","volume":"86","author":"Fehlberg","year":"2016","journal-title":"Diagn Micr Infec Dis"},{"key":"10.1016\/j.jinf.2018.07.006_bib0046","series-title":"EUCAST guidance for antimicrobial susceptibility testing of Burkholderia cepacia complex (BCC) 2013","year":"2013"},{"issue":"2","key":"10.1016\/j.jinf.2018.07.006_bib0047","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1093\/jac\/dkf137","article-title":"Influence of taxonomic status on the in vitro antimicrobial susceptibility of the Burkholderia cepacia complex","volume":"50","author":"Nzula","year":"2002","journal-title":"J Antimicrob Chemoth"},{"issue":"4","key":"10.1016\/j.jinf.2018.07.006_bib0048","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1093\/jac\/dkp253","article-title":"In vitro activity of ceftazidime, ciprofloxacin, meropenem, minocycline, tobramycin and trimethoprim\/sulfamethoxazole against planktonic and sessile Burkholderia cepacia complex bacteria","volume":"64","author":"Peeters","year":"2009","journal-title":"J Antimicrob Chemoth"},{"issue":"6","key":"10.1016\/j.jinf.2018.07.006_bib0049","doi-asserted-by":"crossref","first-page":"23156","DOI":"10.1038\/srep23156","article-title":"Functional genome screening to elucidate the colistin resistance mechanism","volume":"18","author":"Kumar","year":"2016","journal-title":"Sci Rep-UK"},{"key":"10.1016\/j.jinf.2018.07.006_bib0050","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.drup.2016.07.003","article-title":"Antibiotic resistance in Burkholderia species","volume":"28","author":"Rhodes","year":"2016","journal-title":"Drug Resist Updates"},{"issue":"6","key":"10.1016\/j.jinf.2018.07.006_bib0051","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1128\/AAC.30.6.923","article-title":"Involvement of outer membrane of Pseudomonas cepacia in aminoglycoside and polymyxin resistance","volume":"30","author":"Moore","year":"1986","journal-title":"Antimicrob Agents Chemother"},{"issue":"11","key":"10.1016\/j.jinf.2018.07.006_bib0052","doi-asserted-by":"crossref","first-page":"1636","DOI":"10.1128\/AAC.32.11.1636","article-title":"Outer membrane permeability in Pseudomonas cepacia: diminished porin content in a beta-lactam-resistant mutant and in resistant cystic fibrosis isolates","volume":"32","author":"Aronoff","year":"1988","journal-title":"Antimicrob Agents Chemother"},{"issue":"2","key":"10.1016\/j.jinf.2018.07.006_bib0053","doi-asserted-by":"crossref","first-page":"e01941-16","DOI":"10.1128\/AAC.01941-16","article-title":"Exploring the role of the omega-loop in the evolution of ceftazidime resistance in the PenA beta-lactamase from Burkholderia multivorans, an important cystic fibrosis pathogen","volume":"61","author":"Papp-Wallace","year":"2017","journal-title":"Antimicrob Agents Chemother"},{"issue":"8","key":"10.1016\/j.jinf.2018.07.006_bib0054","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0104986","article-title":"The contribution of antibiotic resistance mechanisms in clinical Burkholderia cepacia complex isolates: an emphasis on efflux pump activity","volume":"9","author":"Tseng","year":"2014","journal-title":"PLoS One"},{"issue":"4","key":"10.1016\/j.jinf.2018.07.006_bib0055","doi-asserted-by":"crossref","first-page":"e18902","DOI":"10.1371\/journal.pone.0018902","article-title":"Deciphering the role of RND efflux transporters in Burkholderia cenocepacia","volume":"6","author":"Bazzini","year":"2011","journal-title":"PLoS One"},{"issue":"2","key":"10.1016\/j.jinf.2018.07.006_bib0056","doi-asserted-by":"crossref","first-page":"e16892","DOI":"10.1371\/journal.pone.0016892","article-title":"Involvement of the efflux pumps in chloramphenicol selected strains of Burkholderia thailandensis: proteomic and mechanistic evidence","volume":"6","author":"Biot","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.jinf.2018.07.006_bib0057","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1186\/1476-0711-13-2","article-title":"Investigation of aminoglycoside resistance inducing conditions and a putative AmrAB-OprM efflux system in Burkholderia vietnamiensis","volume":"13","author":"Jassem","year":"2014","journal-title":"Ann Clin Microbiol Antimicrob"},{"issue":"3","key":"10.1016\/j.jinf.2018.07.006_bib0058","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0172723","article-title":"Evaluation of combination therapy for Burkholderia cenocepacia lung infection in different in vitro and in vivo models","volume":"12","author":"Van den Driessche","year":"2017","journal-title":"PLoS One"},{"issue":"3","key":"10.1016\/j.jinf.2018.07.006_bib0059","doi-asserted-by":"crossref","first-page":"e58943","DOI":"10.1371\/journal.pone.0058943","article-title":"Biofilm-grown Burkholderia cepacia complex cells survive antibiotic treatment by avoiding production of reactive oxygen species","volume":"8","author":"Van Acker","year":"2013","journal-title":"PLoS One"},{"issue":"2","key":"10.1016\/j.jinf.2018.07.006_bib0060","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1038\/nrmicro1085","article-title":"The multifarious, multireplicon Burkholderia cepacia complex","volume":"3","author":"Mahenthiralingam","year":"2005","journal-title":"Nat Rev Microbiol"},{"issue":"1","key":"10.1016\/j.jinf.2018.07.006_bib0061","article-title":"Antibiotic treatment for Burkholderia cepacia complex in people with cystic fibrosis experiencing a pulmonary exacerbation","volume":"20","author":"Horsley","year":"2016","journal-title":"Cochrane Database Syst Rev"},{"issue":"10","key":"10.1016\/j.jinf.2018.07.006_bib0062","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD009529.pub2","article-title":"Antibiotic treatment for Burkholderia cepacia complex in people with cystic fibrosis experiencing a pulmonary exacerbation","volume":"17","author":"Horsley","year":"2012","journal-title":"Cochrane Database Syst Rev"},{"issue":"11","key":"10.1016\/j.jinf.2018.07.006_bib0063","article-title":"Eradication therapy for Burkholderia cepacia complex in people with cystic fibrosis","volume":"2","author":"Regan","year":"2016","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.jinf.2018.07.006_bib0064","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD009876.pub2","article-title":"Eradication therapy for Burkholderia cepacia complex in people with cystic fibrosis","volume":"10","author":"Regan","year":"2014","journal-title":"Cochrane Database Syst Rev"},{"issue":"5","key":"10.1016\/j.jinf.2018.07.006_bib0065","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1016\/j.ijantimicag.2016.07.020","article-title":"Combination antimicrobial susceptibility testing of Burkholderia cepacia complex: significance of species","volume":"48","author":"Abbott","year":"2016","journal-title":"Int J Antimicrob Ag"},{"issue":"7","key":"10.1016\/j.jinf.2018.07.006_bib0066","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1021\/acsinfecdis.7b00020","article-title":"Overcoming an extremely drug resistant (XDR) pathogen: Avibactam restores susceptibility to Ceftazidime for Burkholderia cepacia complex isolates from cystic fibrosis patients","volume":"3","author":"Papp-Wallace","year":"2017","journal-title":"ACS Infect Dis"},{"issue":"6","key":"10.1016\/j.jinf.2018.07.006_bib0067","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1002\/ppul.1950170605","article-title":"In vitro suppression of Pseudomonas cepacia after limited exposure to subinhibitory concentrations of amiloride and 5-(N,N-hexamethylene) amiloride","volume":"17","author":"Cohn","year":"1994","journal-title":"Pediatr Pulmonol"},{"issue":"5","key":"10.1016\/j.jinf.2018.07.006_bib0068","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1159\/000239363","article-title":"Verapamil-tobramycin synergy in pseudomonas-cepacia but not pseudomonas-aeruginosa in-vitro","volume":"41","author":"Cohn","year":"1995","journal-title":"Chemotherapy"},{"issue":"1","key":"10.1016\/j.jinf.2018.07.006_bib0069","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.jcf.2012.06.006","article-title":"Inhaled amiloride and tobramycin solutions fail to eradicate Burkholderia dolosa in patients with cystic fibrosis","volume":"12","author":"Uluer","year":"2013","journal-title":"J Cyst Fibros"},{"issue":"4","key":"10.1016\/j.jinf.2018.07.006_bib0070","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1016\/j.jcf.2017.02.008","article-title":"Pilot trial of tobramycin inhalation powder in cystic fibrosis patients with chronic Burkholderia cepacia complex infection","volume":"16","author":"Waters","year":"2017","journal-title":"J Cyst Fibros"},{"issue":"3","key":"10.1016\/j.jinf.2018.07.006_bib0071","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1016\/j.jcf.2013.08.011","article-title":"Inhaled aztreonam for chronic Burkholderia infection in cystic fibrosis: a placebo-controlled trial","volume":"13","author":"Tullis","year":"2014","journal-title":"J Cyst Fibros"},{"issue":"2","key":"10.1016\/j.jinf.2018.07.006_bib0072","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1128\/AAC.43.2.213","article-title":"Comparative in vitro activities of meropenem, imipenem, temocillin, piperacillin, and ceftazidime in combination with tobramycin, rifampin, or ciprofloxacin against Burkholderia cepacia isolates from patients with cystic fibrosis","volume":"43","author":"Bonacorsi","year":"1999","journal-title":"Antimicrob Agents Chemother"},{"issue":"6","key":"10.1016\/j.jinf.2018.07.006_bib0073","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0179776","article-title":"Novel glycopolymer sensitizes Burkholderia cepacia complex isolates from cystic fibrosis patients to tobramycin and meropenem","volume":"12","author":"Narayanaswamy","year":"2017","journal-title":"PLoS One"}],"container-title":["Journal of Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0163445318302184?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0163445318302184?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T21:26:03Z","timestamp":1759008363000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0163445318302184"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,9]]},"references-count":73,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2018,9]]}},"alternative-id":["S0163445318302184"],"URL":"https:\/\/doi.org\/10.1016\/j.jinf.2018.07.006","relation":{},"ISSN":["0163-4453"],"issn-type":[{"value":"0163-4453","type":"print"}],"subject":[],"published":{"date-parts":[[2018,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Burkholderia cepacia complex infections: More complex than the bacterium name suggest","name":"articletitle","label":"Article Title"},{"value":"Journal of Infection","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jinf.2018.07.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 The British Infection Association. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}