{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T13:31:15Z","timestamp":1777296675645,"version":"3.51.4"},"reference-count":27,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2019,4,1]],"date-time":"2019-04-01T00:00:00Z","timestamp":1554076800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,4,1]],"date-time":"2019-04-01T00:00:00Z","timestamp":1554076800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"name":"Chinese National Mega Science and Technology Program on Infectious Diseases","award":["2018ZX10302301"],"award-info":[{"award-number":["2018ZX10302301"]}]},{"name":"Chinese National Mega Science and Technology Program on Infectious Diseases","award":["2018ZX10731301"],"award-info":[{"award-number":["2018ZX10731301"]}]},{"name":"National Key R&D Program of China","award":["2018YFD0500900"],"award-info":[{"award-number":["2018YFD0500900"]}]},{"DOI":"10.13039\/501100001809","name":"National Science Foundation of China","doi-asserted-by":"crossref","award":["31771004"],"award-info":[{"award-number":["31771004"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Shanghai Science and Technology Commission","award":["17ZR1423900"],"award-info":[{"award-number":["17ZR1423900"]}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","journalofinfection.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Infection"],"published-print":{"date-parts":[[2019,4]]},"DOI":"10.1016\/j.jinf.2018.10.016","type":"journal-article","created":{"date-parts":[[2018,12,5]],"date-time":"2018-12-05T13:03:36Z","timestamp":1544015016000},"page":"275-280","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"title":["Differential T cell responses against DosR-associated antigen Rv2028c in BCG-vaccinated populations with tuberculosis infection"],"prefix":"10.1016","volume":"78","author":[{"given":"Hui-Min","family":"Zhao","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rui","family":"Du","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chun-Ling","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ping","family":"Ji","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hai-cong","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kang","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhidong","family":"Hu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shui-Hua","family":"Lu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Douglas B.","family":"Lowrie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6654-3559","authenticated-orcid":false,"given":"Xiao-Yong","family":"Fan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"Suppl 2","key":"10.1016\/j.jinf.2018.10.016_bib0001","doi-asserted-by":"crossref","first-page":"S21","DOI":"10.1093\/infdis\/jiu803","article-title":"Tuberculosis diagnostics in 2015: landscape, priorities, needs, and prospects","volume":"211","author":"Pai","year":"2015","journal-title":"J Infect Dis"},{"key":"10.1016\/j.jinf.2018.10.016_bib0002","doi-asserted-by":"crossref","first-page":"S33","DOI":"10.1038\/nm1221","article-title":"Annulling a dangerous liaison: vaccination strategies against AIDS and tuberculosis","volume":"11","author":"Kaufmann","year":"2005","journal-title":"Nat Med"},{"key":"10.1016\/j.jinf.2018.10.016_bib0003","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/j.imbio.2011.07.008","article-title":"Mycobacterium tuberculosis: immune evasion, latency and reactivation","volume":"217","author":"Gupta","year":"2012","journal-title":"Immunobiology"},{"key":"10.1016\/j.jinf.2018.10.016_bib0004","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1016\/j.vaccine.2013.11.065","article-title":"Immunogenic potential of latency associated antigens against Mycobacterium tuberculosis","volume":"32","author":"Singh","year":"2014","journal-title":"Vaccine"},{"key":"10.1016\/j.jinf.2018.10.016_bib0005","doi-asserted-by":"crossref","first-page":"818","DOI":"10.5588\/ijtld.12.0695","article-title":"Immunogenicity of dormancy-related antigens in individuals infected with Mycobacterium tuberculosis in Japan","volume":"17","author":"Hozumi","year":"2013","journal-title":"Int J Tuberc Lung Dis"},{"key":"10.1016\/j.jinf.2018.10.016_bib0006","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1086\/342416","article-title":"Kinetics of delayed-type hypersensitivity to tuberculin induced by bacille Calmette-Guerin vaccination in northern Malawi","volume":"186","author":"Floyd","year":"2002","journal-title":"J Infect Dis"},{"key":"10.1016\/j.jinf.2018.10.016_bib0007","doi-asserted-by":"crossref","first-page":"201","DOI":"10.4046\/trd.2016.79.4.201","article-title":"Tuberculosis infection and latent tuberculosis","volume":"79","author":"Lee","year":"2016","journal-title":"Tuberc Respir Dis Seoul"},{"key":"10.1016\/j.jinf.2018.10.016_bib0008","doi-asserted-by":"crossref","first-page":"a017830","DOI":"10.1101\/cshperspect.a017830","article-title":"Diagnosis and management of latent tuberculosis infection","volume":"5","author":"Munoz","year":"2015","journal-title":"Cold Spring Harb Perspect Med"},{"key":"10.1016\/j.jinf.2018.10.016_bib0009","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1016\/j.tube.2014.06.009","article-title":"Latent tuberculosis infection: what we know about its genetic control","volume":"94","author":"Kondratieva","year":"2014","journal-title":"Tuberculosis Edinb"},{"key":"10.1016\/j.jinf.2018.10.016_bib0010","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1183\/09031936.00067307","article-title":"Use of a T-cell interferon-gamma release assay for the diagnosis of tuberculous pleurisy","volume":"30","author":"Losi","year":"2007","journal-title":"Eur Respir J"},{"key":"10.1016\/j.jinf.2018.10.016_bib0011","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1038\/nrmicro2236","article-title":"The spectrum of latent tuberculosis: rethinking the biology and intervention strategies","volume":"7","author":"Barry","year":"2009","journal-title":"Nat Rev Microbiol"},{"key":"10.1016\/j.jinf.2018.10.016_bib0012","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1128\/CVI.00111-09","article-title":"Immunogenicity of novel DosR regulon-encoded candidate antigens of Mycobacterium tuberculosis in three high-burden populations in Africa","volume":"16","author":"Black","year":"2009","journal-title":"Clin Vaccine Immunol"},{"key":"10.1016\/j.jinf.2018.10.016_bib0013","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.tube.2011.12.005","article-title":"T cell responses to DosR and Rpf proteins in actively and latently infected individuals from Colombia","volume":"92","author":"Riano","year":"2012","journal-title":"Tuberculosis Edinb"},{"key":"10.1016\/j.jinf.2018.10.016_bib0014","doi-asserted-by":"crossref","first-page":"2052","DOI":"10.1016\/j.micinf.2006.03.018","article-title":"Human T-cell responses to 25 novel antigens encoded by genes of the dormancy regulon of Mycobacterium tuberculosis","volume":"8","author":"Leyten","year":"2006","journal-title":"Microbes Infect"},{"key":"10.1016\/j.jinf.2018.10.016_bib0015","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1084\/jem.20030205","article-title":"Inhibition of respiration by nitric oxide induces a Mycobacterium tuberculosis dormancy program","volume":"198","author":"Voskuil","year":"2003","journal-title":"J Exp Med"},{"key":"10.1016\/j.jinf.2018.10.016_bib0016","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1183\/09031936.00140009","article-title":"Response to Rv2628 latency antigen associates with cured tuberculosis and remote infection","volume":"36","author":"Goletti","year":"2010","journal-title":"Eur Respir J"},{"key":"10.1016\/j.jinf.2018.10.016_bib0017","doi-asserted-by":"crossref","first-page":"e5590","DOI":"10.1371\/journal.pone.0005590","article-title":"Identification of T-cell antigens specific for latent mycobacterium tuberculosis infection","volume":"4","author":"Schuck","year":"2009","journal-title":"Plos One"},{"key":"10.1016\/j.jinf.2018.10.016_bib0018","doi-asserted-by":"crossref","first-page":"e27539","DOI":"10.1371\/journal.pone.0027539","article-title":"Higher frequency of T-cell response to M. tuberculosis latency antigen Rv2628 at the site of active tuberculosis disease than in peripheral blood","volume":"6","author":"Chiacchio","year":"2011","journal-title":"Plos One"},{"key":"10.1016\/j.jinf.2018.10.016_bib0019","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1084\/jem.20030846","article-title":"Transcriptional adaptation of mycobacterium tuberculosis within macrophages: insights into the phagosomal environment","volume":"198","author":"Schnappinger","year":"2003","journal-title":"J Exp Med"},{"key":"10.1016\/j.jinf.2018.10.016_bib0020","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/j.tube.2010.03.013","article-title":"Individual mycobacterium tuberculosis universal stress protein homologues are dispensable in vitro","volume":"90","author":"Hingley-Wilson","year":"2010","journal-title":"Tuberc Edinb"},{"key":"10.1016\/j.jinf.2018.10.016_bib0021","doi-asserted-by":"crossref","first-page":"1907","DOI":"10.1128\/CVI.00482-12","article-title":"Analysis of immune responses against a wide range of Mycobacterium tuberculosis antigens in patients with active pulmonary tuberculosis","volume":"19","author":"Kassa","year":"2012","journal-title":"Clin Vaccine Immunol"},{"key":"10.1016\/j.jinf.2018.10.016_bib0022","doi-asserted-by":"crossref","first-page":"e74080","DOI":"10.1371\/journal.pone.0074080","article-title":"Analysis of host responses to mycobacterium tuberculosis antigens in a multi-site study of subjects with different TB and HIV infection states in sub-Saharan Africa","volume":"8","author":"Sutherland","year":"2013","journal-title":"Plos One"},{"key":"10.1016\/j.jinf.2018.10.016_bib0023","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1016\/j.jmii.2014.02.006","article-title":"Immune responses to latent tuberculosis antigen Rv2659c in Chinese populations","volume":"48","author":"Bai","year":"2015","journal-title":"J Microbiol Immunol Infect"},{"key":"10.1016\/j.jinf.2018.10.016_bib0024","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1016\/j.jinf.2012.08.008","article-title":"Severe disseminated mycobacterial infection in a boy with a novel mutation leading to IFN-gammaR2 deficiency","volume":"65","author":"Kilic","year":"2012","journal-title":"J Infect"},{"key":"10.1016\/j.jinf.2018.10.016_bib0025","doi-asserted-by":"crossref","first-page":"513","DOI":"10.2217\/fmb.12.14","article-title":"How mycobacterium tuberculosis goes to sleep: the dormancy survival regulator DosR a decade later","volume":"7","author":"Boon","year":"2012","journal-title":"Futur Microbiol"},{"key":"10.1016\/j.jinf.2018.10.016_bib0026","first-page":"15","article-title":"Guidelines for using the QuantiFERON-TB test for diagnosing latent mycobacterium tuberculosis infection. Centers for disease control and prevention","volume":"52","author":"Mazurek","year":"2003","journal-title":"MMWR Recomm Rep"},{"key":"10.1016\/j.jinf.2018.10.016_bib0027","doi-asserted-by":"crossref","first-page":"351","DOI":"10.3389\/fmicb.2015.00351","article-title":"Rv2031c of mycobacterium tuberculosis: a master regulator of Rv2028-Rv2031 (HspX) operon","volume":"6","author":"Mushtaq","year":"2015","journal-title":"Front Microbiol"}],"container-title":["Journal of Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0163445318303542?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0163445318303542?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T21:26:45Z","timestamp":1759008405000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0163445318303542"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,4]]},"references-count":27,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2019,4]]}},"alternative-id":["S0163445318303542"],"URL":"https:\/\/doi.org\/10.1016\/j.jinf.2018.10.016","relation":{},"ISSN":["0163-4453"],"issn-type":[{"value":"0163-4453","type":"print"}],"subject":[],"published":{"date-parts":[[2019,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Differential T cell responses against DosR-associated antigen Rv2028c in BCG-vaccinated populations with tuberculosis infection","name":"articletitle","label":"Article Title"},{"value":"Journal of Infection","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jinf.2018.10.016","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 The British Infection Association. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}