{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T07:03:58Z","timestamp":1778569438821,"version":"3.51.4"},"reference-count":54,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,5,10]],"date-time":"2022-05-10T00:00:00Z","timestamp":1652140800000},"content-version":"vor","delay-in-days":9,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100010269","name":"Wellcome Trust","doi-asserted-by":"publisher","award":["082102\/Z\/07\/A"],"award-info":[{"award-number":["082102\/Z\/07\/A"]}],"id":[{"id":"10.13039\/100010269","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010269","name":"Wellcome Trust","doi-asserted-by":"publisher","award":["091634\/Z\/10\/Z"],"award-info":[{"award-number":["091634\/Z\/10\/Z"]}],"id":[{"id":"10.13039\/100010269","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100011725","name":"Meningitis UK","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100011725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013373","name":"NIHR Oxford Biomedical Research Centre","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100013373","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","journalofinfection.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Infection"],"published-print":{"date-parts":[[2022,5]]},"DOI":"10.1016\/j.jinf.2022.02.032","type":"journal-article","created":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T19:35:06Z","timestamp":1646163306000},"page":"658-667","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"title":["Viral vectors expressing group B meningococcal outer membrane proteins induce strong antibody responses but fail to induce functional bactericidal activity"],"prefix":"10.1016","volume":"84","author":[{"given":"Leanne","family":"Marsay","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christina","family":"Dold","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gavin K.","family":"Paterson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuko","family":"Yamaguchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeremy P.","family":"Derrick","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hannah","family":"Chan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ian M.","family":"Feavers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6321-5138","authenticated-orcid":false,"given":"Martin C.J.","family":"Maiden","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Wyllie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adrian V.","family":"Hill","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew J.","family":"Pollard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christine S.","family":"Rollier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.jinf.2022.02.032_bib0001","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/j.coi.2011.03.006","article-title":"Viral vectors as vaccine platforms: deployment in sight","volume":"23","author":"Rollier","year":"2011","journal-title":"Curr Opin Immunol"},{"issue":"1","key":"10.1016\/j.jinf.2022.02.032_bib0002","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1006\/viro.1996.0239","article-title":"A replication-defective human adenovirus recombinant serves as a highly efficacious vaccine carrier","volume":"219","author":"Xiang","year":"1996","journal-title":"Virology"},{"issue":"8","key":"10.1016\/j.jinf.2022.02.032_bib0003","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1038\/nm.1850","article-title":"Effective induction of high-titer antibodies by viral vector vaccines","volume":"14","author":"Draper","year":"2008","journal-title":"Nat Med"},{"issue":"17","key":"10.1016\/j.jinf.2022.02.032_bib0004","doi-asserted-by":"crossref","first-page":"1635","DOI":"10.1056\/NEJMoa1411627","article-title":"A monovalent chimpanzee adenovirus ebola vaccine boosted with MVA","volume":"374","author":"Ewer","year":"2016","journal-title":"N Engl J Med"},{"issue":"1","key":"10.1016\/j.jinf.2022.02.032_bib0005","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1186\/1743-422X-10-349","article-title":"Immunogenicity and efficacy of a chimpanzee adenovirus-vectored rift valley fever vaccine in mice","volume":"10","author":"Warimwe","year":"2013","journal-title":"Virol J"},{"issue":"7383","key":"10.1016\/j.jinf.2022.02.032_bib0006","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1038\/nature10766","article-title":"Vaccine protection against acquisition of neutralization-resistant SIV challenges in rhesus monkeys","volume":"482","author":"Barouch","year":"2012","journal-title":"Nature"},{"key":"10.1016\/j.jinf.2022.02.032_bib0007","doi-asserted-by":"crossref","unstructured":"N. van Doremalen, Lambe T., Spencer A., Belij-Rammerstorfer S., Purusthotham J.N., Port J.R. et\u00a0al., ChAdOx1 nCoV-19 vaccination prevents SARS-CoV-2 pneumonia in rhesus macaques, bioRxiv, p. 2020.05.13.093195, May 2020, doi:10.1101\/2020.05.13.093195.","DOI":"10.1101\/2020.05.13.093195"},{"issue":"23","key":"10.1016\/j.jinf.2022.02.032_bib0008","doi-asserted-by":"crossref","first-page":"11474","DOI":"10.1128\/JVI.75.23.11474-11482.2001","article-title":"Protection against tetanus by needle-free inoculation of adenovirus-vectored nasal and epicutaneous vaccines","volume":"75","author":"Shi","year":"2001","journal-title":"J Virol"},{"issue":"1","key":"10.1016\/j.jinf.2022.02.032_bib0009","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1128\/CVI.00280-12","article-title":"An adenovirus-vectored nasal vaccine confers rapid and sustained protection against anthrax in a single-dose regimen","volume":"20","author":"Zhang","year":"2013","journal-title":"Clin. Vaccine Immunol"},{"issue":"s2","key":"10.1016\/j.jinf.2022.02.032_bib0010","doi-asserted-by":"crossref","first-page":"S54","DOI":"10.1086\/648966","article-title":"Review of meningococcal group B vaccines","volume":"50","author":"Granoff","year":"2010","journal-title":"Clin Infect Dis"},{"issue":"1","key":"10.1016\/j.jinf.2022.02.032_bib0011","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1517\/14712598.2015.983897","article-title":"The capsular group B meningococcal vaccine, 4CMenB: clinical experience and potential efficacy","volume":"15","author":"Rollier","year":"2015","journal-title":"Expert Opin Biol Ther"},{"issue":"6","key":"10.1016\/j.jinf.2022.02.032_bib0012","doi-asserted-by":"crossref","first-page":"1307","DOI":"10.1084\/jem.129.6.1307","article-title":"Human immunity to the meningococcus. I. The role of humoral antibodies","volume":"129","author":"Goldschneider","year":"1969","journal-title":"J Exp Med"},{"issue":"15","key":"10.1016\/j.jinf.2022.02.032_bib0013","doi-asserted-by":"crossref","first-page":"6811","DOI":"10.1073\/pnas.0912115107","article-title":"Structural basis for solute transport, nucleotide regulation, and immunological recognition of Neisseria meningitidis PorB","volume":"107","author":"Tanabe","year":"2010","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"9","key":"10.1016\/j.jinf.2022.02.032_bib0014","doi-asserted-by":"crossref","first-page":"2963","DOI":"10.1128\/iai.59.9.2963-2971.1991","article-title":"Topology of outer membrane porins in pathogenic Neisseria spp","volume":"59","author":"van der Ley","year":"1991","journal-title":"Infect Immun"},{"issue":"7","key":"10.1016\/j.jinf.2022.02.032_bib0015","doi-asserted-by":"crossref","first-page":"2745","DOI":"10.1128\/iai.64.7.2745-2751.1996","article-title":"Specificity of human bactericidal antibodies against PorA P1.7,16 induced with a hexavalent meningococcal outer membrane vesicle vaccine","volume":"64","author":"Van Der Voort","year":"1996","journal-title":"Infect Immun"},{"issue":"4","key":"10.1016\/j.jinf.2022.02.032_bib0016","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1128\/CVI.13.4.486-491.2006","article-title":"The VR2 epitope on the PorA P1.7-2,4 protein is the major target for the immune response elicited by the strain-specific group B meningococcal vaccine MeNZB","volume":"13","author":"Martin","year":"2006","journal-title":"Clin Vaccine Immunol"},{"issue":"4","key":"10.1016\/j.jinf.2022.02.032_bib0017","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1128\/iai.56.4.977-983.1988","article-title":"A pleiotropic iron-uptake mutant of Neisseria meningitidis lacks a 70-kilodalton iron-regulated protein","volume":"56","author":"Dyer","year":"1988","journal-title":"Infect Immun"},{"issue":"12","key":"10.1016\/j.jinf.2022.02.032_bib0018","doi-asserted-by":"crossref","first-page":"4764","DOI":"10.1128\/IAI.05806-11","article-title":"The iron-repressed, AraC-like regulator MpeR activates expression of fetA in Neisseria gonorrhoeae","volume":"79","author":"Hollander","year":"2011","journal-title":"Infect Immun"},{"issue":"9","key":"10.1016\/j.jinf.2022.02.032_bib0019","doi-asserted-by":"crossref","first-page":"2895","DOI":"10.1128\/JB.181.9.2895-2901.1999","article-title":"Ferric enterobactin binding and utilization by Neisseria gonorrhoeae","volume":"181","author":"Biegel Carson","year":"1999","journal-title":"J Bacteriol"},{"issue":"2","key":"10.1016\/j.jinf.2022.02.032_bib0020","doi-asserted-by":"crossref","first-page":"e56746","DOI":"10.1371\/journal.pone.0056746","article-title":"Use of a molecular decoy to segregate transport from antigenicity in the FrpB iron transporter from Neisseria meningitidis","volume":"8","author":"Saleem","year":"2013","journal-title":"PLoS One"},{"issue":"9","key":"10.1016\/j.jinf.2022.02.032_bib0021","doi-asserted-by":"crossref","first-page":"3036","DOI":"10.1128\/iai.58.9.3036-3041.1990","article-title":"Monoclonal antibodies against the 70-kilodalton iron-regulated protein of Neisseria meningitidis are bactericidal and strain specific","volume":"58","author":"Pettersson","year":"1990","journal-title":"Infect Immun"},{"issue":"6","key":"10.1016\/j.jinf.2022.02.032_bib0022","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1016\/0264-410X(94)90314-X","article-title":"Vaccine potential of meningococcal FrpB: studies on surface exposure and functional attributes of common epitopes","volume":"12","author":"Ala'Aldeen","year":"1994","journal-title":"Vaccine"},{"issue":"7","key":"10.1016\/j.jinf.2022.02.032_bib0023","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1128\/CVI.00039-07","article-title":"Functional and specific antibody responses in adult volunteers in New Zealand who were given one of two different meningococcal serogroup B outer membrane vesicle vaccines","volume":"14","author":"Wedege","year":"2007","journal-title":"Clin Vaccine Immunol"},{"issue":"3","key":"10.1016\/j.jinf.2022.02.032_bib0024","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1016\/j.jinf.2015.05.006","article-title":"A novel meningococcal outer membrane vesicle vaccine with constitutive expression of FetA: a phase I clinical trial","volume":"71","author":"Marsay","year":"2015","journal-title":"J Infect"},{"issue":"17\u201318","key":"10.1016\/j.jinf.2022.02.032_bib0025","doi-asserted-by":"crossref","first-page":"2202","DOI":"10.1016\/j.vaccine.2005.01.058","article-title":"The concept of \u2018tailor-made\u2019, protein-based, outer membrane vesicle vaccines against meningococcal disease","volume":"23","author":"Holst","year":"2005","journal-title":"Vaccine"},{"issue":"4","key":"10.1016\/j.jinf.2022.02.032_bib0026","doi-asserted-by":"crossref","first-page":"2130","DOI":"10.1128\/IAI.69.4.2130-2136.2001","article-title":"DNA vaccines expressing a fusion product of outer surface proteins A and C from Borrelia burgdorferi induce protective antibodies suitable for prophylaxis but not for resolution of lyme disease","volume":"69","author":"Wallich","year":"2001","journal-title":"Infect Immun"},{"issue":"5","key":"10.1016\/j.jinf.2022.02.032_bib0027","doi-asserted-by":"crossref","first-page":"3510","DOI":"10.1128\/IAI.69.5.3510-3515.2001","article-title":"Protection against Pseudomonas aeruginosa chronic lung infection in mice by genetic immunization against outer membrane protein F (OprF) of P. aeruginosa","volume":"69","author":"Price","year":"2001","journal-title":"Infect Immun"},{"issue":"1","key":"10.1016\/j.jinf.2022.02.032_bib0028","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1128\/IAI.00943-07","article-title":"A DNA fusion vaccine induces bactericidal antibodies to a peptide epitope from the PorA porin of Neisseria meningitidis","volume":"76","author":"Zhu","year":"2008","journal-title":"Infect Immun"},{"issue":"5","key":"10.1016\/j.jinf.2022.02.032_bib0029","doi-asserted-by":"crossref","first-page":"1070","DOI":"10.1016\/j.jmb.2005.06.061","article-title":"Crystal structure of an anti-meningococcal subtype P1.4 PorA antibody provides basis for peptide-vaccine design","volume":"351","author":"Oomen","year":"2005","journal-title":"J Mol Biol"},{"issue":"SUPPL. 2","key":"10.1016\/j.jinf.2022.02.032_bib0030","doi-asserted-by":"crossref","first-page":"B3","DOI":"10.1016\/j.vaccine.2009.04.071","article-title":"Properties and clinical performance of vaccines containing outer membrane vesicles from Neisseria meningitidis","volume":"27","author":"Holst","year":"2009","journal-title":"Vaccine"},{"issue":"44","key":"10.1016\/j.jinf.2022.02.032_bib0031","doi-asserted-by":"crossref","first-page":"7167","DOI":"10.1016\/j.vaccine.2010.08.068","article-title":"Tailoring subunit vaccine immunogenicity: maximizing antibody and T cell responses by using combinations of adenovirus, poxvirus and protein-adjuvant vaccines against Plasmodium falciparum MSP1","volume":"28","author":"Douglas","year":"2010","journal-title":"Vaccine"},{"issue":"12","key":"10.1016\/j.jinf.2022.02.032_bib0032","doi-asserted-by":"crossref","first-page":"7583","DOI":"10.4049\/jimmunol.1001760","article-title":"Enhancing blood-stage malaria subunit vaccine immunogenicity in rhesus macaques by combining adenovirus, poxvirus, and protein-in-adjuvant vaccines","volume":"185","author":"Draper","year":"2010","journal-title":"J Immunol"},{"issue":"5","key":"10.1016\/j.jinf.2022.02.032_bib0033","doi-asserted-by":"crossref","first-page":"2283","DOI":"10.1128\/IAI.01879-06","article-title":"Priming with an adenovirus 35-circumsporozoite protein (CS) vaccine followed by RTS,S\/AS01B boosting significantly improves immunogenicity to Plasmodium falciparum CS compared to that with either malaria vaccine alone","volume":"75","author":"Stewart","year":"2007","journal-title":"Infect Immun"},{"issue":"10","key":"10.1016\/j.jinf.2022.02.032_bib0034","doi-asserted-by":"crossref","first-page":"4217","DOI":"10.1128\/iai.61.10.4217-4224.1993","article-title":"Use of transformation to construct antigenic hybrids of the class 1 outer membrane protein in Neisseria meningitidis","volume":"61","author":"van der Ley","year":"1993","journal-title":"Infect Immun"},{"issue":"10","key":"10.1016\/j.jinf.2022.02.032_bib0035","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0006870","article-title":"A simian-adenovirus-vectored rabies vaccine suitable for thermostabilisation and clinical development for low-cost single-dose pre-exposure prophylaxis","volume":"12","author":"Wang","year":"2018","journal-title":"PLoS Negl Trop Dis"},{"issue":"10","key":"10.1016\/j.jinf.2022.02.032_bib0036","doi-asserted-by":"crossref","first-page":"2073","DOI":"10.1093\/cid\/ciz653","volume":"70","author":"Cicconi","year":"2020","journal-title":"Clin Infect Dis"},{"issue":"10249","key":"10.1016\/j.jinf.2022.02.032_bib0037","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1016\/S0140-6736(20)31604-4","article-title":"Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: a preliminary report of a phase 1\/2, single-blind, randomised controlled trial","volume":"396","author":"Folegatti","year":"2020","journal-title":"Lancet"},{"issue":"JAN","key":"10.1016\/j.jinf.2022.02.032_bib0038","doi-asserted-by":"crossref","first-page":"1998","DOI":"10.3389\/fimmu.2017.01998","article-title":"Assessment of antibodies induced by multivalent transmission-blocking malaria vaccines","volume":"8","author":"Menon","year":"2018","journal-title":"Front Immunol"},{"issue":"1","key":"10.1016\/j.jinf.2022.02.032_bib0039","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1186\/s13058-018-1023-x","article-title":"Polyfunctional anti-human epidermal growth factor receptor 3 (anti-HER3) antibodies induced by HER3 vaccines have multiple mechanisms of antitumor activity against therapy resistant and triple negative breast cancers","volume":"20","author":"Osada","year":"2018","journal-title":"Breast Cancer Res"},{"issue":"17","key":"10.1016\/j.jinf.2022.02.032_bib0040","doi-asserted-by":"crossref","first-page":"1673","DOI":"10.1089\/104303403322542310","article-title":"Protective immunity evoked against anthrax lethal toxin after a single intramuscular administration of an adenovirus-based vaccine encoding humanized protective antigen","volume":"14","author":"Tan","year":"2003","journal-title":"Hum. Gene Ther"},{"issue":"3","key":"10.1016\/j.jinf.2022.02.032_bib0041","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1111\/j.1574-695X.2008.00518.x","article-title":"Mucosal vaccination with a multicomponent adenovirus-vectored vaccine protects against Streptococcus pneumoniae infection in the lung","volume":"55","author":"Ar\u00e9valo","year":"2009","journal-title":"FEMS Immunol Med Microbiol"},{"issue":"7","key":"10.1016\/j.jinf.2022.02.032_bib0042","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1128\/CVI.00150-16","article-title":"A replication-defective human type 5 adenovirus-based trivalent vaccine confers complete protection against plague in mice and nonhuman primates","volume":"23","author":"Sha","year":"2016","journal-title":"Clin Vaccine Immunol"},{"issue":"3","key":"10.1016\/j.jinf.2022.02.032_bib0043","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1016\/j.vaccine.2018.11.036","article-title":"Vaccination with the Staphylococcus aureus secreted proteins EapH1 and EapH2 impacts both S. aureus carriage and invasive disease","volume":"37","author":"Elshina","year":"2019","journal-title":"Vaccine"},{"key":"10.1016\/j.jinf.2022.02.032_bib0044","doi-asserted-by":"crossref","DOI":"10.3389\/fcimb.2017.00256","article-title":"Biological functions of the secretome of Neisseria meningitidis","volume":"7","author":"Tommassen","year":"2017","journal-title":"Front Cell Infect Microbiol"},{"issue":"4","key":"10.1016\/j.jinf.2022.02.032_bib0045","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/0882-4010(87)90059-3","article-title":"Protective efficacy of monoclonal antibodies to class 1 and class 3 outer membrane proteins of Neisseria meningitidis B:15:P1.16 in infant rat infection model: new prospects for vaccine development","volume":"3","author":"Saukkonen","year":"1987","journal-title":"Microb Pathog"},{"issue":"1","key":"10.1016\/j.jinf.2022.02.032_bib0046","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1111\/j.0300-9475.2004.01362.x","article-title":"The four mouse IgG isotypes differ extensively in bactericidal and opsonophagocytic activity when reacting with the P1.16 epitope on the outer membrane PorA protein of Neisseria meningitidis","volume":"59","author":"Michaelsen","year":"2004","journal-title":"Scand J Immunol"},{"issue":"1","key":"10.1016\/j.jinf.2022.02.032_bib0047","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.femsim.2004.11.013","article-title":"Effect of a booster dose of serogroup B meningococcal vaccine on antibody response to Neisseria meningitidis in mice vaccinated with different immunization schedules","volume":"44","author":"Gioia","year":"2005","journal-title":"FEMS Immunol Med Microbiol"},{"issue":"6","key":"10.1016\/j.jinf.2022.02.032_bib0048","doi-asserted-by":"crossref","first-page":"e20977","DOI":"10.1371\/journal.pone.0020977","article-title":"Transgene optimization, immunogenicity and in vitro efficacy of viral vectored vaccines expressing two alleles of Plasmodium falciparum AMA1","volume":"6","author":"Biswas","year":"2011","journal-title":"PLoS One"},{"issue":"4","key":"10.1016\/j.jinf.2022.02.032_bib0049","first-page":"366","article-title":"Expression of thioredoxin random peptide libraries on the Escherichia coli cell surfeice as functional fusions to flagellin: a system designed for exploring protein-protein interactions","volume":"13","author":"Lu","year":"1995","journal-title":"BioTechnology"},{"key":"10.1016\/j.jinf.2022.02.032_bib0050","doi-asserted-by":"crossref","unstructured":"S. Maharjan, Saleem M., Feavers I.M., Wheeler J.X., Care R. and Derrick J., Editor's Choice Dissection of the function of the RmpM periplasmic protein from Neisseria meningitidis, doi:10.1099\/mic.0.000227.","DOI":"10.1099\/mic.0.000227"},{"issue":"16","key":"10.1016\/j.jinf.2022.02.032_bib0051","doi-asserted-by":"crossref","first-page":"3201","DOI":"10.1016\/j.vaccine.2020.03.001","article-title":"An assessment of the use of hepatitis B Virus core protein virus-like particles to display heterologous antigens from Neisseria meningitidis","volume":"38","author":"Aston-Deaville","year":"2020","journal-title":"Vaccine"},{"issue":"11","key":"10.1016\/j.jinf.2022.02.032_bib0052","doi-asserted-by":"crossref","first-page":"3027","DOI":"10.1099\/00221287-144-11-3027","article-title":"Immunization with recombinant class 1 outermembrane protein from Neisseria meningitidis: influence of liposomes and adjuvants an antibody avidity, recognition of native protein and the induction of a bactericidal immune response against meningococci","volume":"144","author":"Christodoulides","year":"1998","journal-title":"Microbiology"},{"issue":"7","key":"10.1016\/j.jinf.2022.02.032_bib0053","doi-asserted-by":"crossref","first-page":"e40385","DOI":"10.1371\/journal.pone.0040385","article-title":"A novel chimpanzee adenovirus vector with low human seroprevalence: improved systems for vector derivation and comparative immunogenicity","volume":"7","author":"Dicks","year":"2012","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/j.jinf.2022.02.032_bib0054","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41598-019-43139-0","article-title":"Immunogenicity profiling of protein antigens from capsular group B Neisseria meningitidis","volume":"9","author":"Awanye","year":"2019","journal-title":"Sci Rep"}],"container-title":["Journal of Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0163445322001220?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0163445322001220?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T21:33:55Z","timestamp":1759008835000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0163445322001220"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5]]},"references-count":54,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2022,5]]}},"alternative-id":["S0163445322001220"],"URL":"https:\/\/doi.org\/10.1016\/j.jinf.2022.02.032","relation":{},"ISSN":["0163-4453"],"issn-type":[{"value":"0163-4453","type":"print"}],"subject":[],"published":{"date-parts":[[2022,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Viral vectors expressing group B meningococcal outer membrane proteins induce strong antibody responses but fail to induce functional bactericidal activity","name":"articletitle","label":"Article Title"},{"value":"Journal of Infection","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jinf.2022.02.032","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Authors. Published by Elsevier Ltd on behalf of The British Infection Association.","name":"copyright","label":"Copyright"}]}}