{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T14:53:22Z","timestamp":1791384802475,"version":"4.3.3"},"reference-count":38,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,10,22]],"date-time":"2024-10-22T00:00:00Z","timestamp":1729555200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100017594","name":"Medical Science and Technology Project of Zhejiang Province","doi-asserted-by":"publisher","award":["2022KY183"],"award-info":[{"award-number":["2022KY183"]}],"id":[{"id":"10.13039\/501100017594","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004731","name":"Natural Science Foundation of Zhejiang Province","doi-asserted-by":"publisher","award":["LZY24H150003"],"award-info":[{"award-number":["LZY24H150003"]}],"id":[{"id":"10.13039\/501100004731","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82073610"],"award-info":[{"award-number":["82073610"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2023YFC2307100"],"award-info":[{"award-number":["2023YFC2307100"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014718","name":"Innovative Research Group Project of the National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100014718","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","journalofinfection.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Infection"],"published-print":{"date-parts":[[2024,12]]},"DOI":"10.1016\/j.jinf.2024.106331","type":"journal-article","created":{"date-parts":[[2024,10,25]],"date-time":"2024-10-25T02:44:55Z","timestamp":1729824295000},"page":"106331","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"title":["Clinical characteristics and prognosis of bloodstream infections with carbapenem-resistant Gram-negative organisms in patients with hematological malignancies: A multicenter case-control study in China"],"prefix":"10.1016","volume":"89","author":[{"given":"Junxin","family":"Zhou","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shanshan","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinhong","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jintao","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ping","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huangdu","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuke","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanfei","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qin","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shujuan","family":"Ji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhihui","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoting","family":"Hua","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8013-5770","authenticated-orcid":false,"given":"Xueqing","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoxing","family":"Du","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2903-918X","authenticated-orcid":false,"given":"Yunsong","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.jinf.2024.106331_bib1","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1097\/QCO.0000000000000038","article-title":"Antimicrobial-resistant Gram-negative bacteria in febrile neutropenic patients with cancer: current epidemiology and clinical impact","volume":"27","author":"Trecarichi","year":"2014","journal-title":"Curr Opin Infect Dis"},{"issue":"4","key":"10.1016\/j.jinf.2024.106331_bib2","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1016\/j.jmii.2023.01.017","article-title":"Guidelines for the diagnosis, treatment, prevention and control of infections caused by carbapenem-resistant gram-negative bacilli","volume":"56","author":"Zeng","year":"2023","journal-title":"J Microbiol Immunol Infect"},{"key":"10.1016\/j.jinf.2024.106331_bib3","article-title":"High mortality associated with inappropriate initial antibiotic therapy in hematological malignancies with Klebsiella pneumoniae bloodstream infections","volume":"14","author":"Ma","year":"2024","journal-title":"Sci Rep"},{"issue":"6","key":"10.1016\/j.jinf.2024.106331_bib4","doi-asserted-by":"crossref","first-page":"1068","DOI":"10.1093\/cid\/ciz319","article-title":"Inappropriate empirical antibiotic treatment in high-risk neutropenic patients with bacteremia in the era of multidrug resistance","volume":"70","author":"Martinez-Nadal","year":"2020","journal-title":"Clin Infect Dis"},{"issue":"1","key":"10.1016\/j.jinf.2024.106331_bib5","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1007\/s15010-019-01370-x","article-title":"Inappropriate initial antimicrobial therapy for hematological malignancies patients with Gram-negative bloodstream infections","volume":"48","author":"Tang","year":"2020","journal-title":"Infection"},{"key":"10.1016\/j.jinf.2024.106331_bib6","doi-asserted-by":"crossref","first-page":"1422","DOI":"10.3389\/fmicb.2020.01422","article-title":"Infections due to carbapenem-resistant bacteria in patients with hematologic malignancies","volume":"11","author":"Lalaoui","year":"2020","journal-title":"Front Microbiol"},{"key":"10.1016\/j.jinf.2024.106331_bib7","doi-asserted-by":"crossref","first-page":"4241","DOI":"10.2147\/IDR.S374904","article-title":"Risk factors for mortality and outcomes in hematological malignancy patients with carbapenem-resistant Klebsiella pneumoniae bloodstream infections","volume":"15","author":"Meng","year":"2022","journal-title":"Infect Drug Resist"},{"issue":"4","key":"10.1016\/j.jinf.2024.106331_bib8","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1007\/s15010-018-1151-3","article-title":"Prognostic factors and scoring model of hematological malignancies patients with bloodstream infections","volume":"46","author":"Tang","year":"2018","journal-title":"Infection"},{"key":"10.1016\/j.jinf.2024.106331_bib9","doi-asserted-by":"crossref","DOI":"10.3389\/fcimb.2023.1156651","article-title":"Assessment of mortality-related risk factors and effective antimicrobial regimens for treatment of bloodstream infections caused by carbapenem-resistant Pseudomonas aeruginosa in patients with hematological diseases","volume":"13","author":"Zhen","year":"2023","journal-title":"Front Cell Infect Microbiol"},{"issue":"4","key":"10.1016\/j.jinf.2024.106331_bib10","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1007\/s15010-019-01277-7","article-title":"Derivation of a quick Pitt bacteremia score to predict mortality in patients with Gram-negative bloodstream infection","volume":"47","author":"Battle","year":"2019","journal-title":"Infection"},{"issue":"4","key":"10.1016\/j.jinf.2024.106331_bib11","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1080\/21505594.2016.1213472","article-title":"Carbapenem-resistant Enterobacteriaceae in special populations: solid organ transplant recipients, stem cell transplant recipients, and patients with hematologic malignancies","volume":"8","author":"Pouch","year":"2017","journal-title":"Virulence"},{"issue":"6","key":"10.1016\/j.jinf.2024.106331_bib12","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijantimicag.2023.106806","article-title":"Bloodstream infections due to Gram-negative bacteria in patients with hematologic malignancies: updated epidemiology and risk factors for multidrug-resistant strains in an Italian perspective survey","volume":"61","author":"Trecarichi","year":"2023","journal-title":"Int J Antimicrob Agents"},{"issue":"7","key":"10.1016\/j.jinf.2024.106331_bib13","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.3201\/eid2007.130094","article-title":"Carbapenemase-producing Klebsiella pneumoniae and hematologic malignancies","volume":"20","author":"Pagano","year":"2014","journal-title":"Emerg Infect Dis"},{"key":"10.1016\/j.jinf.2024.106331_bib14","article-title":"High mortality associated with inappropriate initial antibiotic therapy in hematological malignancies with Klebsiella pneumoniae bloodstream infections","volume":"14","author":"Ma","year":"2024","journal-title":"Sci Rep"},{"issue":"7","key":"10.1016\/j.jinf.2024.106331_bib15","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1007\/s10096-016-2895-2","article-title":"Acinetobacter baumannii bacteraemia in patients with haematological malignancy: a multicentre retrospective study from the Infection Working Party of Jiangsu Society of Hematology","volume":"36","author":"Wang","year":"2017","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"10.1016\/j.jinf.2024.106331_bib16","doi-asserted-by":"crossref","first-page":"4943","DOI":"10.2147\/IDR.S419064","article-title":"Clinical characteristics and prognosis of bloodstream infection with carbapenem-resistant Pseudomonas aeruginosa in patients with hematologic malignancies","volume":"16","author":"Yuan","year":"2023","journal-title":"Infect Drug Resist"},{"issue":"10","key":"10.1016\/j.jinf.2024.106331_bib17","doi-asserted-by":"crossref","first-page":"1709","DOI":"10.1007\/s00134-018-5360-0","article-title":"Mortality attributable to different Klebsiella susceptibility patterns and to the coverage of empirical antibiotic therapy: a cohort study on patients admitted to the ICU with infection","volume":"44","author":"GiViTI Steering Committee","year":"2018","journal-title":"Intensive Care Med"},{"issue":"7","key":"10.1016\/j.jinf.2024.106331_bib18","doi-asserted-by":"crossref","first-page":"4035","DOI":"10.1128\/AAC.02636-14","article-title":"Surveillance of carbapenem-resistant Klebsiella pneumoniae: tracking molecular epidemiology and outcomes through a regional network","volume":"58","author":"van Duin","year":"2014","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.jinf.2024.106331_bib19","doi-asserted-by":"crossref","first-page":"4188","DOI":"10.1038\/s41467-021-24448-3","article-title":"A genomic surveillance framework and genotyping tool for Klebsiella pneumoniae and its related species complex","volume":"12","author":"Lam","year":"2021","journal-title":"Nat Commun"},{"issue":"3","key":"10.1016\/j.jinf.2024.106331_bib20","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijantimicag.2021.106284","article-title":"Antibiotic strategies and clinical outcomes for patients with carbapenem-resistant Gram-negative bacterial bloodstream infection","volume":"57","author":"Qu","year":"2021","journal-title":"Int J Antimicrob Agents"},{"issue":"2","key":"10.1016\/j.jinf.2024.106331_bib21","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1007\/s00134-022-06944-2","article-title":"Epidemiology and outcomes of hospital-acquired bloodstream infections in intensive care unit patients: the EUROBACT-2 international cohort study","volume":"49","author":"Tabah","year":"2023","journal-title":"Intensive Care Med"},{"key":"10.1016\/j.jinf.2024.106331_bib22","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1186\/s12911-024-02504-4","article-title":"Prediction of carbapenem-resistant gram-negative bacterial bloodstream infection in intensive care unit based on machine learning","volume":"24","author":"Liang","year":"2024","journal-title":"BMC Med Inf Decis Mak"},{"issue":"2","key":"10.1016\/j.jinf.2024.106331_bib23","doi-asserted-by":"crossref","DOI":"10.1016\/j.bjid.2023.102758","article-title":"Prevalence of bloodstream infection pathogens in hemato-oncological patients and predictors of carbapenem-resistant gram-negative bacterial infections during febrile neutropenia","volume":"27","author":"Schonardie","year":"2023","journal-title":"Braz J Infect Dis"},{"issue":"6","key":"10.1016\/j.jinf.2024.106331_bib24","first-page":"12","article-title":"Emergence of ceftazidime- and avibactam-resistant Klebsiella pneumoniae carbapenemase-producing Pseudomonas aeruginosa in China","volume":"6","author":"Zhu","year":"2021"},{"key":"10.1016\/j.jinf.2024.106331_bib25","article-title":"A potential high-risk clone of Pseudomonas aeruginosa ST463","volume":"12","author":"Hu","year":"2021","journal-title":"Front Microbiol"},{"issue":"10","key":"10.1016\/j.jinf.2024.106331_bib26","doi-asserted-by":"crossref","first-page":"2136","DOI":"10.3201\/eid2910.230509","article-title":"Pseudomonas aeruginosa high-risk sequence type 463 co-producing KPC-2 and AFM-1 Carbapenemases, China, 2020\u20132022","volume":"29","author":"Zhang","year":"2023","journal-title":"Emerg Infect Dis"},{"issue":"3","key":"10.1016\/j.jinf.2024.106331_bib27","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1038\/s41564-024-01612-1","article-title":"Carbapenem-resistant Klebsiella pneumoniae capsular types, antibiotic resistance and virulence factors in China: a longitudinal, multi-centre study","volume":"9","author":"Hu","year":"2024","journal-title":"Nat Microbiol"},{"key":"10.1016\/j.jinf.2024.106331_bib28","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1186\/s12941-017-0199-8","article-title":"The efficacy and safety of tigecycline for the treatment of bloodstream infections: a systematic review and meta-analysis","volume":"16","author":"Wang","year":"2017","journal-title":"Ann Clin Microbiol Antimicrob"},{"key":"10.1016\/j.jinf.2024.106331_bib29","doi-asserted-by":"crossref","DOI":"10.1128\/AAC.01744-21","article-title":"Impact of empirical antibiotic regimens on mortality in neutropenic patients with bloodstream infection presenting with septic shock","volume":"66","author":"Chumbita","year":"2022","journal-title":"Antimicrob Agents Chemother"},{"issue":"2","key":"10.1016\/j.jinf.2024.106331_bib30","doi-asserted-by":"crossref","DOI":"10.1128\/spectrum.00084-22","article-title":"Emergence of high-level cefiderocol resistance in carbapenem-resistant Klebsiella pneumoniae from bloodstream infections in patients with hematologic malignancies in China","volume":"10","author":"Lan","year":"2022","journal-title":"Microbiol Spectr"},{"issue":"3","key":"10.1016\/j.jinf.2024.106331_bib31","doi-asserted-by":"crossref","DOI":"10.1128\/spectrum.02670-21","article-title":"Occurrence of high levels of cefiderocol resistance in carbapenem-resistant Escherichia coli before its approval in China: a report from China CRE-Network","volume":"10","author":"Wang","year":"2022","journal-title":"Microbiol Spectr"},{"issue":"8","key":"10.1016\/j.jinf.2024.106331_bib32","doi-asserted-by":"crossref","DOI":"10.1016\/j.cmi.2021.04.016","article-title":"Cross-resistance to cefiderocol and ceftazidime\u2013avibactam in KPC \u03b2-lactamase mutants and the inoculum effect","volume":"27","author":"Hobson","year":"2021","journal-title":"Clin Microbiol Infect"},{"issue":"5","key":"10.1016\/j.jinf.2024.106331_bib33","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1007\/s40265-016-0545-8","article-title":"Review of eravacycline, a novel fluorocycline antibacterial agent","volume":"76","author":"Zhanel","year":"2016","journal-title":"Drugs"},{"issue":"9","key":"10.1016\/j.jinf.2024.106331_bib34","doi-asserted-by":"crossref","first-page":"2508","DOI":"10.1093\/jac\/dkaa206","article-title":"In vitro dynamics and mechanisms of resistance development to imipenem and imipenem\/relebactam in Pseudomonas aeruginosa","volume":"75","author":"Gomis-Font","year":"2020","journal-title":"J Antimicrob Chemother"},{"issue":"11","key":"10.1016\/j.jinf.2024.106331_bib35","doi-asserted-by":"crossref","DOI":"10.1128\/aac.00675-23","article-title":"blaKPC-2\u00a0overexpression and\u00a0blaGES-5\u00a0carriage as major imipenem\/relebactam resistance mechanisms in\u00a0Pseudomonas aeruginosa\u00a0high-risk clones ST463 and ST235, respectively, in China","volume":"67","author":"Li","year":"2023","journal-title":"Antimicrob Agents Chemother"},{"issue":"4","key":"10.1016\/j.jinf.2024.106331_bib36","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1093\/jac\/dkab496","article-title":"Comparative analysis of in vitro dynamics and mechanisms of ceftolozane\/tazobactam and imipenem\/relebactam resistance development in Pseudomonas aeruginosa XDR high-risk clones","volume":"77","author":"Gomis-Font","year":"2022","journal-title":"J Antimicrob Chemother"},{"issue":"ement_4","key":"10.1016\/j.jinf.2024.106331_bib37","doi-asserted-by":"crossref","first-page":"S386","DOI":"10.1093\/cid\/ciaa1522","article-title":"Risk factors and outcomes of antibiotic-resistant Pseudomonas aeruginosa bloodstream infection in adult patients with acute leukemia","volume":"71","author":"Zhao","year":"2020","journal-title":"Clin Infect Dis"},{"issue":"2","key":"10.1016\/j.jinf.2024.106331_bib38","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijantimicag.2023.106874","article-title":"CRO infection and the Use of MRSA-active medication for prophylaxis affect the prognosis of patients with hematological malignancies after CAR-T infusion","volume":"62","author":"Yang","year":"2023","journal-title":"Int J Antimicrob Agents"}],"container-title":["Journal of Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0163445324002652?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0163445324002652?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T09:31:35Z","timestamp":1762248695000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0163445324002652"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12]]},"references-count":38,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2024,12]]}},"alternative-id":["S0163445324002652"],"URL":"https:\/\/doi.org\/10.1016\/j.jinf.2024.106331","relation":{},"ISSN":["0163-4453"],"issn-type":[{"value":"0163-4453","type":"print"}],"subject":[],"published":{"date-parts":[[2024,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Clinical characteristics and prognosis of bloodstream infections with carbapenem-resistant Gram-negative organisms in patients with hematological malignancies: A multicenter case-control study in China","name":"articletitle","label":"Article Title"},{"value":"Journal of Infection","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jinf.2024.106331","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Author(s). Published by Elsevier Ltd on behalf of The British Infection Association.","name":"copyright","label":"Copyright"}],"article-number":"106331"}}