{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T18:52:03Z","timestamp":1786992723535,"version":"build-2736575974"},"reference-count":43,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T00:00:00Z","timestamp":1762473600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000050","name":"National Heart Lung and Blood Institute","doi-asserted-by":"publisher","award":["R01HL130750"],"award-info":[{"award-number":["R01HL130750"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart Lung and Blood Institute","doi-asserted-by":"publisher","award":["R01HL146377"],"award-info":[{"award-number":["R01HL146377"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006492","name":"National Institute of Allergy and Infectious Diseases Division of Intramural Research","doi-asserted-by":"publisher","award":["R01AI141900"],"award-info":[{"award-number":["R01AI141900"]}],"id":[{"id":"10.13039\/100006492","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006492","name":"National Institute of Allergy and Infectious Diseases Division of Intramural Research","doi-asserted-by":"publisher","award":["R01AI099628"],"award-info":[{"award-number":["R01AI099628"]}],"id":[{"id":"10.13039\/100006492","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006492","name":"National Institute of Allergy and Infectious Diseases Division of Intramural Research","doi-asserted-by":"publisher","award":["U19AI110820"],"award-info":[{"award-number":["U19AI110820"]}],"id":[{"id":"10.13039\/100006492","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100017046","name":"School of Medicine, University of Maryland","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100017046","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008510","name":"University of Maryland","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008510","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000861","name":"Burroughs Wellcome Fund","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000861","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000011","name":"Howard Hughes Medical Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000011","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100001949","name":"American Society of Tropical Medicine and Hygiene","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100001949","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","journalofinfection.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Infection"],"published-print":{"date-parts":[[2025,12]]},"DOI":"10.1016\/j.jinf.2025.106655","type":"journal-article","created":{"date-parts":[[2025,11,14]],"date-time":"2025-11-14T09:06:17Z","timestamp":1763111177000},"page":"106655","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Plasmodium falciparum gene expression signatures and antibody profiling implicate the fikk, phist, and surf multigene families in severe malaria syndromes"],"prefix":"10.1016","volume":"91","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-4074-9606","authenticated-orcid":false,"given":"Bryan E.","family":"Cummings","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8256-3290","authenticated-orcid":false,"given":"Emily M.","family":"Stucke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Drissa","family":"Coulibaly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan G.","family":"Lawton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rafal S.","family":"Sobota","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdoulaye Kassoum","family":"Kone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bourama","family":"Kane","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bour\u00e9ima","family":"Guindo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bourama","family":"Tangara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mody","family":"Sissoko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fay\u00e7al","family":"Maiga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karim","family":"Traore","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aichatou","family":"Diawara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amidou","family":"Traore","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2679-035X","authenticated-orcid":false,"given":"Ali","family":"Thera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antoine","family":"Dara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amadou","family":"Niangaly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Modibo","family":"Daou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Issa","family":"Diarra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Youssouf","family":"Tolo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Savy","family":"Sebastian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aarti","family":"Jain","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rie","family":"Nakajima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Algis","family":"Jasinskas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8650-8731","authenticated-orcid":false,"given":"Emily K.","family":"Silzel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Biraj","family":"Shrestha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1964-7130","authenticated-orcid":false,"given":"Amed","family":"Ouattara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James B.","family":"Munro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3874-581X","authenticated-orcid":false,"given":"Matthew B.","family":"Laurens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kirsten E.","family":"Lyke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8866-7667","authenticated-orcid":false,"given":"Kieran","family":"Tebben","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haikel","family":"Bogale","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0045-9888","authenticated-orcid":false,"given":"Christopher V.","family":"Plowe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahamadou S.","family":"Sissoko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bourema","family":"Kouriba","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shannon","family":"Takala-Harrison","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip L.","family":"Felgner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6502-7026","authenticated-orcid":false,"given":"Joana C.","family":"Silva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ogobara K.","family":"Doumbo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahamadou A.","family":"Thera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6045-3322","authenticated-orcid":false,"given":"Mark A.","family":"Travassos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jinf.2025.106655_bib1","doi-asserted-by":"crossref","unstructured":"Severe Malaria. Trop Med Int Health;2014;19(s1):7\u2013131.","DOI":"10.1111\/tmi.12313_2"},{"key":"10.1016\/j.jinf.2025.106655_bib2","unstructured":"World malaria report 2022 [Internet] [cited 2022 Dec 16]. Available from: \u3008https:\/\/www.who.int\/teams\/global-malaria-programme\/reports\/world-malaria-report-2022\u3009."},{"issue":"Suppl. 1","key":"10.1016\/j.jinf.2025.106655_bib3","doi-asserted-by":"crossref","first-page":"S57","DOI":"10.4269\/ajtmh.2001.64.57","article-title":"Gaps in the childhood malaria burden in Africa: cerebral malaria, neurological sequelae, anemia, respiratory distress, hypoglycemia, and complications of pregnancy","volume":"64","author":"Murphy","year":"2001","journal-title":"Am J Trop Med Hyg"},{"issue":"211","key":"10.1016\/j.jinf.2025.106655_bib4","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.3007432","article-title":"Piecing together the puzzle of severe malaria","volume":"5","author":"Cunnington","year":"2013","journal-title":"Sci Transl Med"},{"issue":"1","key":"10.1016\/j.jinf.2025.106655_bib5","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1182\/asheducation-2009.1.87","article-title":"Malaria, erythrocytic infection, and anemia","volume":"2009","author":"Haldar","year":"2009","journal-title":"Hematol Am Soc Hematol Educ Program"},{"issue":"2","key":"10.1016\/j.jinf.2025.106655_bib6","doi-asserted-by":"crossref","first-page":"315","DOI":"10.4269\/ajtmh.22-0135","article-title":"Serologic and cytokine profiles of children with concurrent cerebral malaria and severe malarial anemia are distinct from other subtypes of severe malaria","volume":"107","author":"Sobota","year":"2022","journal-title":"Am J Trop Med Hyg"},{"issue":"21","key":"10.1016\/j.jinf.2025.106655_bib7","doi-asserted-by":"crossref","first-page":"1399","DOI":"10.1056\/NEJM199505253322102","article-title":"Indicators of life-threatening malaria in African children","volume":"332","author":"Marsh","year":"1995","journal-title":"N Engl J Med"},{"issue":"9","key":"10.1016\/j.jinf.2025.106655_bib8","doi-asserted-by":"crossref","first-page":"1427","DOI":"10.7150\/ijbs.7.1427","article-title":"Severe malarial anemia: innate immunity and pathogenesis","volume":"7","author":"Perkins","year":"2011","journal-title":"Int J Biol Sci"},{"issue":"2","key":"10.1016\/j.jinf.2025.106655_bib9","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1002\/ajh.27152","article-title":"Retention of uninfected red blood cells causing congestive splenomegaly is the major mechanism of anemia in malaria","volume":"99","author":"Kho","year":"2024","journal-title":"Am J Hematol"},{"issue":"2","key":"10.1016\/j.jinf.2025.106655_bib10","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.pt.2019.12.002","article-title":"Autoimmune anemia in malaria","volume":"36","author":"Rivera-Correa","year":"2020","journal-title":"Trends Parasitol"},{"issue":"8","key":"10.1016\/j.jinf.2025.106655_bib11","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1038\/nrmicro.2017.47","article-title":"Variant surface antigens of Plasmodium falciparum and their roles in severe malaria","volume":"15","author":"Wahlgren","year":"2017","journal-title":"Nat Rev Microbiol"},{"issue":"1","key":"10.1016\/j.jinf.2025.106655_bib12","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1111\/imr.12807","article-title":"Cerebral Plasmodium falciparum malaria: the role of PfEMP1 in its pathogenesis and immunity, and PfEMP1\u2010based vaccines to prevent it","volume":"293","author":"Jensen","year":"2020","journal-title":"Immunol Rev"},{"issue":"1","key":"10.1016\/j.jinf.2025.106655_bib13","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1086\/504689","article-title":"Genetic analysis of circulating and sequestered populations of Plasmodium falciparum in fatal pediatric malaria","volume":"194","author":"Montgomery","year":"2006","journal-title":"J Infect Dis"},{"issue":"6906","key":"10.1016\/j.jinf.2025.106655_bib14","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1038\/nature01097","article-title":"Genome sequence of the human malaria parasite Plasmodium falciparum","volume":"419","author":"Gardner","year":"2002","journal-title":"Nature"},{"issue":"3","key":"10.1016\/j.jinf.2025.106655_bib15","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pbio.2004328","article-title":"The Plasmodium falciparum transcriptome in severe malaria reveals altered expression of genes involved in important processes including surface antigen-encoding var genes","volume":"16","author":"Tonkin-Hill","year":"2018","journal-title":"PLoS Biol"},{"issue":"12","key":"10.1016\/j.jinf.2025.106655_bib16","doi-asserted-by":"crossref","first-page":"2187","DOI":"10.1093\/infdis\/jiac086","article-title":"Transcriptome analysis of Plasmodium falciparum isolates from benin reveals specific gene expression associated with cerebral malaria","volume":"225","author":"Guillochon","year":"2022","journal-title":"J Infect Dis"},{"key":"10.1016\/j.jinf.2025.106655_bib17","article-title":"Shifts in the clinical epidemiology of severe malaria after scaling up control strategies in Mali","volume":"13","author":"Kone","year":"2022","journal-title":"Front Neurol"},{"key":"10.1016\/j.jinf.2025.106655_bib18","doi-asserted-by":"crossref","unstructured":"Traore K, Thera A, Coulibaly D, Kon\u00e9 AK, Guindo B, Tangara B, et al. A qualitative method to assess a history of cerebral malaria in malian children; 2025 [cited 2025 Oct 28]. Available from: \u3008https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/112\/1\/article-p72.xml\u3009.","DOI":"10.4269\/ajtmh.23-0564"},{"issue":"6","key":"10.1016\/j.jinf.2025.106655_bib19","doi-asserted-by":"crossref","DOI":"10.1128\/mSystems.00226-21","article-title":"Successful profiling of Plasmodium falciparum var gene expression in clinical samples via a custom capture array","volume":"6","author":"Stucke","year":"2021","journal-title":"mSystems"},{"issue":"4","key":"10.1016\/j.jinf.2025.106655_bib20","doi-asserted-by":"crossref","DOI":"10.1128\/msystems.00258-22","article-title":"Determination of the stage composition of plasmodium infections from bulk gene expression data","volume":"7","author":"Tebben","year":"2022","journal-title":"mSystems"},{"issue":"3","key":"10.1016\/j.jinf.2025.106655_bib21","doi-asserted-by":"crossref","DOI":"10.1186\/gb-2010-11-3-r25","article-title":"A scaling normalization method for differential expression analysis of RNA-seq data","volume":"11","author":"Robinson","year":"2010","journal-title":"Genome Biol"},{"key":"10.1016\/j.jinf.2025.106655_bib22","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1186\/s12936-023-04710-3","article-title":"Haematological parameters and their correlation with the degree of malaria parasitaemia among outpatients attending a polyclinic","volume":"22","author":"Antwi-Baffour","year":"2023","journal-title":"Malar J"},{"issue":"2","key":"10.1016\/j.jinf.2025.106655_bib23","doi-asserted-by":"crossref","first-page":"187","DOI":"10.2174\/156652406776055212","article-title":"Immune responses to asexual blood-stages of malaria parasites","volume":"6","author":"Yazdani","year":"2006","journal-title":"Curr Mol Med"},{"issue":"1","key":"10.1016\/j.jinf.2025.106655_bib24","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1038\/75556","article-title":"Gene ontology: tool for the unification of biology","volume":"25","author":"Ashburner","year":"2000","journal-title":"Nat Genet"},{"key":"10.1016\/j.jinf.2025.106655_bib25","series-title":"Malaria immunology: targeting the surface of infected erythrocytes","article-title":"Protein microarrays as a tool to analyze antibody responses to variant surface antigens expressed on the surface of Plasmodium falciparum\u2013infected erythrocytes","author":"Zhou","year":"2022"},{"issue":"1","key":"10.1016\/j.jinf.2025.106655_bib26","doi-asserted-by":"crossref","first-page":"6281","DOI":"10.1038\/s41598-018-24462-4","article-title":"Children with cerebral malaria or severe malarial anaemia lack immunity to distinct variant surface antigen subsets","volume":"8","author":"Travassos","year":"2018","journal-title":"Sci Rep"},{"issue":"1","key":"10.1016\/j.jinf.2025.106655_bib27","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-021-92974-7","article-title":"Malian adults maintain serologic responses to virulent PfEMP1s amid seasonal patterns of fluctuation","volume":"11","author":"Ventimiglia","year":"2021","journal-title":"Sci Rep"},{"issue":"43","key":"10.1016\/j.jinf.2025.106655_bib28","doi-asserted-by":"crossref","first-page":"17857","DOI":"10.1074\/jbc.M117.802769","article-title":"Compositional and expression analyses of the glideosome during the Plasmodium life cycle reveal an additional myosin light chain required for maximum motility","volume":"292","author":"Green","year":"2017","journal-title":"J Biol Chem"},{"issue":"2","key":"10.1016\/j.jinf.2025.106655_bib29","doi-asserted-by":"crossref","DOI":"10.1128\/mBio.03377-20","article-title":"Malaria parasite schizont egress antigen-1 plays an essential role in nuclear segregation during schizogony","volume":"12","author":"Perrin","year":"2021","journal-title":"mBio"},{"issue":"6186","key":"10.1016\/j.jinf.2025.106655_bib30","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1126\/science.1254417","article-title":"Antibodies to PfSEA-1 block parasite egress from RBCs and protect against malaria infection","volume":"344","author":"Raj","year":"2014","journal-title":"Science"},{"issue":"1","key":"10.1016\/j.jinf.2025.106655_bib31","doi-asserted-by":"crossref","DOI":"10.1128\/Spectrum.00008-21","article-title":"Single-cell RNA sequencing reveals cellular heterogeneity and stage transition under temperature stress in synchronized Plasmodium falciparum cells","volume":"9","author":"Rawat","year":"2021","journal-title":"Microbiol Spectr"},{"key":"10.1016\/j.jinf.2025.106655_bib32","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2020.611190","article-title":"Interaction analysis of a Plasmodium falciparum PHISTa-like protein and PfEMP1 proteins","volume":"11","author":"Yang","year":"2020","journal-title":"Front Microbiol"},{"issue":"11","key":"10.1016\/j.jinf.2025.106655_bib33","doi-asserted-by":"crossref","first-page":"1853","DOI":"10.1084\/jem.20041392","article-title":"SURFIN is a polymorphic antigen expressed on Plasmodium falciparum merozoites and infected erythrocytes","volume":"201","author":"Winter","year":"2005","journal-title":"J Exp Med"},{"issue":"6","key":"10.1016\/j.jinf.2025.106655_bib34","doi-asserted-by":"crossref","first-page":"848","DOI":"10.1038\/s41564-020-0702-4","article-title":"An exported kinase family mediates species-specific erythrocyte remodelling and virulence in human malaria","volume":"5","author":"Davies","year":"2020","journal-title":"Nat Microbiol"},{"issue":"5","key":"10.1016\/j.jinf.2025.106655_bib35","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/j.ijpara.2014.01.003","article-title":"An exported kinase (FIKK4.2) that mediates virulence-associated changes in Plasmodium falciparum-infected red blood cells","volume":"44","author":"Kats","year":"2014","journal-title":"Int J Parasitol"},{"issue":"50","key":"10.1016\/j.jinf.2025.106655_bib36","doi-asserted-by":"crossref","first-page":"19987","DOI":"10.1073\/pnas.1309247110","article-title":"Maurer\u2019s clefts, the enigma of Plasmodium falciparum","volume":"110","author":"Mundwiler-Pachlatko","year":"2013","journal-title":"Proc Natl Acad Sci USA"},{"issue":"1","key":"10.1016\/j.jinf.2025.106655_bib37","doi-asserted-by":"crossref","first-page":"5037","DOI":"10.1038\/s41467-024-48259-4","article-title":"Entire expressed peripheral blood transcriptome in pediatric severe malarial anemia","volume":"15","author":"Anyona","year":"2024","journal-title":"Nat Commun"},{"issue":"13","key":"10.1016\/j.jinf.2025.106655_bib38","doi-asserted-by":"crossref","first-page":"1501","DOI":"10.1016\/j.ijpara.2004.10.008","article-title":"Malarial anaemia: mechanisms and implications of insufficient erythropoiesis during blood-stage malaria","volume":"34","author":"Chang","year":"2004","journal-title":"Int J Parasitol"},{"issue":"2","key":"10.1016\/j.jinf.2025.106655_bib39","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1038\/s44321-023-00010-0","article-title":"Infected erythrocytes and plasma proteomics reveal a specific protein signature of severe malaria","volume":"16","author":"Fraering","year":"2024","journal-title":"EMBO Mol Med"},{"issue":"3","key":"10.1016\/j.jinf.2025.106655_bib40","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1038\/6560","article-title":"Immunity to non-cerebral severe malaria is acquired after one or two infections","volume":"5","author":"Gupta","year":"1999","journal-title":"Nat Med"},{"issue":"1414","key":"10.1016\/j.jinf.2025.106655_bib41","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1098\/rspb.1999.0600","article-title":"Acquired immunity and postnatal clinical protection in childhood cerebral malaria","volume":"266","author":"Gupta","year":"1999","journal-title":"Proc Biol Sci"},{"issue":"1801","key":"10.1016\/j.jinf.2025.106655_bib42","article-title":"Gradual acquisition of immunity to severe malaria with increasing exposure","volume":"282","author":"Griffin","year":"2015","journal-title":"Proc Biol Sci"},{"key":"10.1016\/j.jinf.2025.106655_bib43","doi-asserted-by":"crossref","first-page":"2021","DOI":"10.1038\/s41467-024-46416-3","article-title":"Gene expression analyses reveal differences in children\u2019s response to malaria according to their age","volume":"15","author":"Tebben","year":"2024","journal-title":"Nat Commun"}],"container-title":["Journal of Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0163445325002555?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0163445325002555?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T12:28:24Z","timestamp":1773923304000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0163445325002555"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12]]},"references-count":43,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025,12]]}},"alternative-id":["S0163445325002555"],"URL":"https:\/\/doi.org\/10.1016\/j.jinf.2025.106655","relation":{},"ISSN":["0163-4453"],"issn-type":[{"value":"0163-4453","type":"print"}],"subject":[],"published":{"date-parts":[[2025,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Plasmodium falciparum gene expression signatures and antibody profiling implicate the fikk, phist, and surf multigene families in severe malaria syndromes","name":"articletitle","label":"Article Title"},{"value":"Journal of Infection","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jinf.2025.106655","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Ltd on behalf of British Infection Association.","name":"copyright","label":"Copyright"}],"article-number":"106655"}}