{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T12:16:27Z","timestamp":1792671387793,"version":"4.5.0"},"reference-count":24,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,5,26]],"date-time":"2026-05-26T00:00:00Z","timestamp":1779753600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100007657","name":"Univerza v Ljubljani","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007657","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004329","name":"Slovenian Research and Innovation Agency","doi-asserted-by":"publisher","award":["P3\\u20130083"],"award-info":[{"award-number":["P3\\u20130083"]}],"id":[{"id":"10.13039\/501100004329","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004329","name":"Slovenian Research and Innovation Agency","doi-asserted-by":"publisher","award":["P3\\u20130296"],"award-info":[{"award-number":["P3\\u20130296"]}],"id":[{"id":"10.13039\/501100004329","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","journalofinfection.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Infection"],"published-print":{"date-parts":[[2026,7]]},"DOI":"10.1016\/j.jinf.2026.106776","type":"journal-article","created":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T23:40:44Z","timestamp":1779925244000},"page":"106776","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Emerging human pathogen: Identifying Spiroplasma ixodetis as a frequent cause of unlocalised febrile illness"],"prefix":"10.1016","volume":"93","author":[{"given":"Mi\u0161a","family":"Korva","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Petra","family":"Bogovi\u010d","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8068-7302","authenticated-orcid":false,"given":"Nata\u0161a","family":"Knap","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8999-4923","authenticated-orcid":false,"given":"Rok","family":"Kogoj","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-9525-4053","authenticated-orcid":false,"given":"Jan","family":"Slune\u010dko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0478-2009","authenticated-orcid":false,"given":"Samo","family":"Zakotnik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4596-7931","authenticated-orcid":false,"given":"Alen","family":"Sulji\u010d","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katarina","family":"Resman Rus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4708-0602","authenticated-orcid":false,"given":"Patricija","family":"Pozvek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4163-0503","authenticated-orcid":false,"given":"Franc","family":"Strle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6243-0688","authenticated-orcid":false,"given":"Tatjana","family":"Av\u0161i\u010d-\u017dupanc","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miroslav","family":"Petrovec","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jinf.2026.106776_bib1","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0004040","article-title":"Estimating the burden of febrile illnesses","volume":"9","author":"Crump","year":"2015","journal-title":"PLoS Negl Trop Dis"},{"key":"10.1016\/j.jinf.2026.106776_bib2","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1586\/eri.09.118","article-title":"A clear and present danger: tick-borne diseases in Europe","volume":"8","author":"Heyman","year":"2010","journal-title":"Expert Rev Anti Infect Ther"},{"key":"10.1016\/j.jinf.2026.106776_bib3","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1186\/s13071-023-05959-y","article-title":"Predicting the distribution of Ixodes ricinus and Dermacentor reticulatus in Europe: a comparison of climate niche modelling approaches","volume":"16","author":"Noll","year":"2023","journal-title":"Parasit Vectors"},{"key":"10.1016\/j.jinf.2026.106776_bib4","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2025.1632832","article-title":"Ticks and tick-borne diseases in the northern hemisphere affecting humans","volume":"16","author":"Boulanger","year":"2025","journal-title":"Front Microbiol"},{"key":"10.1016\/j.jinf.2026.106776_bib5","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0103188","article-title":"Are patients with erythema migrans who have leukopenia and\/or thrombocytopenia coinfected with Anaplasma phagocytophilum or tick-borne encephalitis virus?","volume":"9","author":"Strle","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.jinf.2026.106776_bib6","article-title":"Current debates and advances in tick microbiome research","volume":"1","author":"Wu-Chuang","year":"2021","journal-title":"Curr Res Parasitol Vector Borne Dis"},{"key":"10.1016\/j.jinf.2026.106776_bib7","doi-asserted-by":"crossref","first-page":"2983","DOI":"10.2741\/2027","article-title":"Gasparich G E. Spiroplasmas: evolutionary relationships and biodiversity","volume":"11","author":"Regassa","year":"2006","journal-title":"Front Biosci"},{"key":"10.1016\/j.jinf.2026.106776_bib8","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1016\/j.ttbdis.2015.05.002","article-title":"Isolation and propagation of a Spiroplasma sp. from Slovakian Ixodes ricinus ticks in Ixodes spp. cell lines","volume":"6","author":"Bell-Sakyi","year":"2015","journal-title":"Ticks Tick Borne Dis"},{"key":"10.1016\/j.jinf.2026.106776_bib9","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1128\/JCM.02841-14","article-title":"First human systemic infection caused by Spiroplasma","volume":"53","author":"Aquilino","year":"2015","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.jinf.2026.106776_bib10","doi-asserted-by":"crossref","first-page":"2382","DOI":"10.3201\/eid2412.180567","article-title":"Disseminated Spiroplasma apis infection in patient with agammaglobulinemia, France","volume":"24","author":"Etienne","year":"2018","journal-title":"Emerg Infect Dis"},{"key":"10.1016\/j.jinf.2026.106776_bib11","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.3201\/eid3106.240954","article-title":"Multicenter retrospective study of Spiroplasma ixodetis infantile cataract in 8 countries in Europe","volume":"31","author":"Van Os","year":"2025","journal-title":"Emerg Infect Dis"},{"key":"10.1016\/j.jinf.2026.106776_bib12","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1097\/NEN.0000000000000033","article-title":"The case for involvement of spiroplasma in the pathogenesis of transmissible spongiform encephalopathies","volume":"73","author":"Bastian","year":"2014","journal-title":"J Neuropathol Exp Neurol"},{"key":"10.1016\/j.jinf.2026.106776_bib13","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1099\/00207713-45-1-23","article-title":"Spiroplasma ixodetis sp. nov., a new species from Ixodes pacificus ticks collected in Oregon","volume":"45","author":"Tully","year":"1995","journal-title":"Int J Syst Bacteriol"},{"key":"10.1016\/j.jinf.2026.106776_bib14","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1016\/j.ttbdis.2019.02.001","article-title":"Phylogenetics of the Spiroplasma ixodetis endosymbiont reveals past transfers between ticks and other arthropods","volume":"10","author":"Binetruy","year":"2019","journal-title":"Ticks Tick Borne Dis"},{"key":"10.1016\/j.jinf.2026.106776_bib15","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1007\/s00417-002-0453-3","article-title":"First evidence of an endogenous Spiroplasma sp. infection in humans manifesting as unilateral cataract associated with anterior uveitis in a premature baby","volume":"240","author":"Lorenz","year":"2002","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"10.1016\/j.jinf.2026.106776_bib16","doi-asserted-by":"crossref","first-page":"2511","DOI":"10.1111\/ajt.13254","article-title":"Hepatitis from Spiroplasma sp. in an immunocompromised patient","volume":"15","author":"Mueller","year":"2015","journal-title":"Am J Transplant"},{"key":"10.1016\/j.jinf.2026.106776_bib17","doi-asserted-by":"crossref","first-page":"340","DOI":"10.3201\/eid2602.191097","article-title":"Ocular Spiroplasma ixodetis in newborns, France","volume":"26","author":"Matet","year":"2020","journal-title":"Emerg Infect Dis"},{"key":"10.1016\/j.jinf.2026.106776_bib18","doi-asserted-by":"crossref","first-page":"1681","DOI":"10.3201\/eid2808.212524","article-title":"Spiroplasma ixodetis infections in immunocompetent and immunosuppressed patients after tick exposure, Sweden","volume":"28","author":"Eimer","year":"2022","journal-title":"Emerg Infect Dis"},{"key":"10.1016\/j.jinf.2026.106776_bib19","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1186\/s12886-024-03480-z","article-title":"Spiroplasma infection as a cause of severe congenital keratouveitis, cataract and glaucoma","volume":"24","author":"Van Haecke","year":"2024","journal-title":"BMC Ophthalmol"},{"key":"10.1016\/j.jinf.2026.106776_bib20","doi-asserted-by":"crossref","DOI":"10.3389\/fcimb.2025.1667422","article-title":"Development and performance evaluation of a clinical metagenomics approach for identifying pathogens in the whole blood from patients with undifferentiated fever","volume":"15","author":"Slune\u010dko","year":"2025","journal-title":"Front Cell Infect Microbiol"},{"key":"10.1016\/j.jinf.2026.106776_bib21","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1016\/j.ttbdis.2019.02.008","article-title":"Isolation of known and potentially pathogenic tick-borne microorganisms from European ixodid ticks using tick cell lines","volume":"10","author":"Palomar","year":"2019","journal-title":"Ticks Tick Borne Dis"},{"key":"10.1016\/j.jinf.2026.106776_bib22","first-page":"S1600","article-title":"Spiroplasma infection complicated by macrophage activation syndrome and fulminant hepatitis in a kidney transplant recipient","volume":"13","author":"Farhat","year":"2026","journal-title":"Am J Transplant"},{"key":"10.1016\/j.jinf.2026.106776_bib23","doi-asserted-by":"crossref","DOI":"10.1016\/j.isci.2026.115233","article-title":"A human-associated Spiroplasma ixodetis lineage responsible for infantile cataracts and adult febrile illness","volume":"29","author":"Buysse","year":"2026","journal-title":"iScience"},{"key":"10.1016\/j.jinf.2026.106776_bib24","doi-asserted-by":"crossref","first-page":"2159","DOI":"10.3201\/eid3111.250545","article-title":"Spiroplasma ixodetis in ticks removed from humans, Sweden and \u00c5land Islands, Finland","volume":"31","author":"Lager","year":"2025","journal-title":"Emerg Infect Dis"}],"container-title":["Journal of Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0163445326001015?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0163445326001015?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T09:47:14Z","timestamp":1783158434000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0163445326001015"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":24,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["S0163445326001015"],"URL":"https:\/\/doi.org\/10.1016\/j.jinf.2026.106776","relation":{},"ISSN":["0163-4453"],"issn-type":[{"value":"0163-4453","type":"print"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Emerging human pathogen: Identifying Spiroplasma ixodetis as a frequent cause of unlocalised febrile illness","name":"articletitle","label":"Article Title"},{"value":"Journal of Infection","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jinf.2026.106776","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Author(s). Published by Elsevier Ltd on behalf of British Infection Association.","name":"copyright","label":"Copyright"}],"article-number":"106776"}}