{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T04:20:41Z","timestamp":1781842841207,"version":"3.54.5"},"reference-count":58,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,10,1]],"date-time":"2016-10-01T00:00:00Z","timestamp":1475280000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100002665","name":"Research Committee, Aristotle University of Thessaloniki","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002665","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Inorganic Biochemistry"],"published-print":{"date-parts":[[2016,10]]},"DOI":"10.1016\/j.jinorgbio.2016.04.017","type":"journal-article","created":{"date-parts":[[2016,4,30]],"date-time":"2016-04-30T21:36:26Z","timestamp":1462052186000},"page":"240-249","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":20,"special_numbering":"C","title":["Hybrid catechin silica nanoparticle influence on Cu(II) toxicity and morphological lesions in primary neuronal cells"],"prefix":"10.1016","volume":"163","author":[{"given":"E.","family":"Halevas","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.M.","family":"Nday","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Salifoglou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jinorgbio.2016.04.017_bb0005","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1097\/01.jnen.0000228202.35163.c4","volume":"65","author":"Wishart","year":"2006","journal-title":"J. Neuropathol. Exp. Neurol."},{"key":"10.1016\/j.jinorgbio.2016.04.017_bb0010","doi-asserted-by":"crossref","first-page":"1202","DOI":"10.1111\/ejn.12504","volume":"39","author":"Liao","year":"2014","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.jinorgbio.2016.04.017_bb0015","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1001\/jamaneurol.2013.5847","volume":"71","author":"Bloom","year":"2014","journal-title":"JAMA Neurol."},{"key":"10.1016\/j.jinorgbio.2016.04.017_bb0020","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1016\/j.neuron.2014.05.004","volume":"82","author":"Spires-Jones","year":"2014","journal-title":"Neuron"},{"key":"10.1016\/j.jinorgbio.2016.04.017_bb0025","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1016\/j.arr.2013.03.002","volume":"12","author":"Crimins","year":"2013","journal-title":"Ageing Res. Rev."},{"key":"10.1016\/j.jinorgbio.2016.04.017_bb0030","doi-asserted-by":"crossref","first-page":"143","DOI":"10.3389\/fnagi.2014.00143","volume":"6","author":"Opazo","year":"2014","journal-title":"Front. Aging Neurosci."},{"key":"10.1016\/j.jinorgbio.2016.04.017_bb0035","doi-asserted-by":"crossref","first-page":"S277","DOI":"10.3233\/JAD-2012-129011","volume":"33","author":"Bush","year":"2013","journal-title":"J. Alzheimers Dis."},{"key":"10.1016\/j.jinorgbio.2016.04.017_bb0040","doi-asserted-by":"crossref","first-page":"145","DOI":"10.3233\/JAD-2006-102-303","volume":"10","author":"Adlard","year":"2006","journal-title":"J. Alzheimers Dis."},{"key":"10.1016\/j.jinorgbio.2016.04.017_bb0045","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1021\/cb400080f","volume":"8","author":"Savelieff","year":"2013","journal-title":"ACS Chem. Biol."},{"key":"10.1016\/j.jinorgbio.2016.04.017_bb0050","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1196\/annals.1306.012","volume":"1012","author":"Huang","year":"2004","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.jinorgbio.2016.04.017_bb0055","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1016\/j.ces.2005.06.019","volume":"61","author":"Xu","year":"2006","journal-title":"Chem. Eng. Sci."},{"key":"10.1016\/j.jinorgbio.2016.04.017_bb0060","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1016\/j.msec.2006.04.010","volume":"27","author":"Nguyen-Ngoc","year":"2007","journal-title":"Mater. Sci. Eng. C"},{"key":"10.1016\/j.jinorgbio.2016.04.017_bb0065","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/j.ijpharm.2006.09.024","volume":"330","author":"Maver","year":"2007","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.jinorgbio.2016.04.017_bb0070","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1002\/1097-4636(200111)57:2<313::AID-JBM1173>3.0.CO;2-E","volume":"57","author":"Radin","year":"2001","journal-title":"J. Biomed. Mater. Res."},{"key":"10.1016\/j.jinorgbio.2016.04.017_bb0075","doi-asserted-by":"crossref","first-page":"3417","DOI":"10.1021\/la701688t","volume":"24","author":"Yang","year":"2008","journal-title":"Langmuir"},{"key":"10.1016\/j.jinorgbio.2016.04.017_bb0080","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1002\/jbm.820290106","volume":"29","author":"Otsuka","year":"1995","journal-title":"J. Biomed. Mater. Res."},{"key":"10.1016\/j.jinorgbio.2016.04.017_bb0085","doi-asserted-by":"crossref","first-page":"3139","DOI":"10.1166\/jnn.2006.410","volume":"6","author":"Wen","year":"2006","journal-title":"J. Nanosci. Nanotechnol."},{"key":"10.1016\/j.jinorgbio.2016.04.017_bb0090","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1002\/jbm.10188","volume":"61","author":"Meseguer-Olmo","year":"2002","journal-title":"J. Biomed. Mater. Res."},{"key":"10.1016\/j.jinorgbio.2016.04.017_bb0095","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/S0142-9612(99)00148-9","volume":"21","author":"Kortesuo","year":"2000","journal-title":"Biomaterials"},{"key":"10.1016\/j.jinorgbio.2016.04.017_bb0100","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1002\/(SICI)1097-4636(200008)51:2<164::AID-JBM4>3.0.CO;2-W","volume":"51","author":"Elisseeff","year":"2000","journal-title":"J. Biomed. Mater. Res."},{"key":"10.1016\/j.jinorgbio.2016.04.017_bb0105","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1002\/1097-4636(20000905)51:3<343::AID-JBM7>3.0.CO;2-D","volume":"51","author":"Alcantar","year":"2000","journal-title":"J. Biomed. Mater. Res."},{"key":"10.1016\/j.jinorgbio.2016.04.017_bb0110","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1038\/nmat2608","volume":"9","author":"Horcajada","year":"2010","journal-title":"Nat. Mater."},{"key":"10.1016\/j.jinorgbio.2016.04.017_bb0115","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/0885-4505(88)90060-6","volume":"39","author":"Ratty","year":"1988","journal-title":"Biochem. Med. Metab. Biol."},{"key":"10.1016\/j.jinorgbio.2016.04.017_bb0120","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/0955-2863(95)00168-9","volume":"7","author":"Cook","year":"1996","journal-title":"J. Nutr. Biochem."},{"key":"10.1016\/j.jinorgbio.2016.04.017_bb0125","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/j.jnutbio.2005.10.005","volume":"17","author":"Sutherland","year":"2006","journal-title":"J. Nutr. Biochem."},{"key":"10.1016\/j.jinorgbio.2016.04.017_bb0130","doi-asserted-by":"crossref","first-page":"S243","DOI":"10.1093\/ajcn\/81.1.243S","volume":"81","author":"Williamson","year":"2005","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1016\/j.jinorgbio.2016.04.017_bb0135","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1179\/135100002125000424","volume":"7","author":"Nie","year":"2002","journal-title":"Redox Rep."},{"key":"10.1016\/j.jinorgbio.2016.04.017_bb0140","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1093\/jn\/132.3.341","volume":"132","author":"Adcocks","year":"2002","journal-title":"J. Nutr."},{"key":"10.1016\/j.jinorgbio.2016.04.017_bb0145","doi-asserted-by":"crossref","first-page":"2418","DOI":"10.1021\/jf011339n","volume":"50","author":"Nakagawa","year":"2002","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.jinorgbio.2016.04.017_bb0150","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1016\/S0304-4165(99)00034-3","volume":"1427","author":"Huang","year":"1999","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.jinorgbio.2016.04.017_bb0155","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1021\/cr00099a003","volume":"90","author":"Hench","year":"1990","journal-title":"Chem. Rev."},{"key":"10.1016\/j.jinorgbio.2016.04.017_bb0160","doi-asserted-by":"crossref","first-page":"4095","DOI":"10.1016\/j.apsusc.2010.01.090","volume":"256","author":"Yang","year":"2010","journal-title":"Appl. Surf. Sci."},{"key":"10.1016\/j.jinorgbio.2016.04.017_bb0165","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/S0378-5173(99)00403-2","volume":"195","author":"Ahola","year":"2000","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.jinorgbio.2016.04.017_bb0170","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1016\/S0731-7085(03)00529-6","volume":"34","author":"Pralhad","year":"2004","journal-title":"J. Pharm. Biomed. Anal."},{"key":"10.1016\/j.jinorgbio.2016.04.017_bb0175","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1002\/jps.22266","volume":"100","author":"Natarajan","year":"2011","journal-title":"J. Pharm. Sci."},{"key":"10.1016\/j.jinorgbio.2016.04.017_bb0180","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1155\/2011\/628790","volume":"8","author":"Polu","year":"2011","journal-title":"J. Chem."},{"key":"10.1016\/j.jinorgbio.2016.04.017_bb0185","doi-asserted-by":"crossref","first-page":"6639","DOI":"10.3390\/ijms13066639","volume":"13","author":"Shameli","year":"2012","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.jinorgbio.2016.04.017_bb0190","doi-asserted-by":"crossref","first-page":"2224","DOI":"10.1021\/cm703215r","volume":"20","author":"Elimelech","year":"2008","journal-title":"Chem. Mater."},{"key":"10.1016\/j.jinorgbio.2016.04.017_bb0195","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.crci.2013.07.008","volume":"17","author":"Kiasat","year":"2014","journal-title":"C. R. Chim."},{"key":"10.1016\/j.jinorgbio.2016.04.017_bb0200","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1007\/s11051-010-9966-6","volume":"13","author":"Santhanalakshmi","year":"2011","journal-title":"J. Nanopart. Res."},{"key":"10.1016\/j.jinorgbio.2016.04.017_bb0205","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1007\/s11671-008-9196-3","volume":"4","author":"Mehta","year":"2009","journal-title":"Nanoscale Res. Lett."},{"key":"10.1016\/j.jinorgbio.2016.04.017_bb0210","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1023\/A:1010174224567","volume":"53","author":"de Farias","year":"1998","journal-title":"J. Therm. Anal. Calorim."},{"key":"10.1016\/j.jinorgbio.2016.04.017_bb0215","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1080\/00387010902827718","volume":"42","author":"Ansari","year":"2009","journal-title":"Spectrosc. Lett."},{"key":"10.1016\/j.jinorgbio.2016.04.017_bb0220","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1246\/cl.2004.406","volume":"33","author":"Wu","year":"2004","journal-title":"Chem. Lett."},{"key":"10.1016\/j.jinorgbio.2016.04.017_bb0225","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.jinorgbio.2015.01.001","volume":"145","author":"Nday","year":"2015","journal-title":"J. Inorg. Biochem."},{"key":"10.1016\/j.jinorgbio.2016.04.017_bb0230","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/j.jconrel.2003.08.021","volume":"93","author":"Yeo","year":"2003","journal-title":"J. Control. Release"},{"key":"10.1016\/j.jinorgbio.2016.04.017_bb0235","first-page":"380","volume":"12","author":"Hwang","year":"2006","journal-title":"J. Ind. Eng. Chem."},{"key":"10.1016\/j.jinorgbio.2016.04.017_bb0240","doi-asserted-by":"crossref","first-page":"1598","DOI":"10.1007\/s11270-013-1598-x","volume":"224","author":"Halevas","year":"2013","journal-title":"Water Air Soil Pollut."},{"key":"10.1016\/j.jinorgbio.2016.04.017_bb0245","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/j.jcis.2010.02.012","volume":"345","author":"Du","year":"2010","journal-title":"J. Colloid Interface Sci."},{"key":"10.1016\/j.jinorgbio.2016.04.017_bb0250","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.1016\/j.biomaterials.2009.10.046","volume":"31","author":"He","year":"2010","journal-title":"Biomaterials"},{"key":"10.1016\/j.jinorgbio.2016.04.017_bb0255","doi-asserted-by":"crossref","first-page":"2778","DOI":"10.1039\/b822444g","volume":"19","author":"Zhao","year":"2009","journal-title":"J. Mater. Chem."},{"key":"10.1016\/j.jinorgbio.2016.04.017_bb0260","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.jcis.2005.06.047","volume":"293","author":"Wilhelm","year":"2006","journal-title":"J. Colloid Interface Sci."},{"key":"10.1016\/j.jinorgbio.2016.04.017_bb0265","doi-asserted-by":"crossref","first-page":"4880","DOI":"10.1007\/BF01129956","volume":"254","author":"Sato","year":"1990","journal-title":"J. Mater. Sci."},{"key":"10.1016\/j.jinorgbio.2016.04.017_bb0270","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1080\/10717540600812653","volume":"14","author":"Prokopowicz","year":"2007","journal-title":"Drug Deliv."},{"key":"10.1016\/j.jinorgbio.2016.04.017_bb0275","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/j.brainres.2010.07.008","volume":"1352","author":"Nday","year":"2010","journal-title":"Brain Res."},{"key":"10.1016\/j.jinorgbio.2016.04.017_bb0280","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1002\/jnr.23143","volume":"91","author":"Gaier","year":"2013","journal-title":"J. Neurosci. Res."},{"key":"10.1016\/j.jinorgbio.2016.04.017_bb0285","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/0304-3940(89)90565-X","volume":"103","author":"Kardos","year":"1989","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.jinorgbio.2016.04.017_bb0290","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1002\/syn.890020408","volume":"2","author":"Hartter","year":"1988","journal-title":"Synapse"}],"container-title":["Journal of Inorganic Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0162013416301027?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0162013416301027?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,6,2]],"date-time":"2025-06-02T23:25:21Z","timestamp":1748906721000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0162013416301027"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,10]]},"references-count":58,"alternative-id":["S0162013416301027"],"URL":"https:\/\/doi.org\/10.1016\/j.jinorgbio.2016.04.017","relation":{},"ISSN":["0162-0134"],"issn-type":[{"value":"0162-0134","type":"print"}],"subject":[],"published":{"date-parts":[[2016,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Hybrid catechin silica nanoparticle influence on Cu(II) toxicity and morphological lesions in primary neuronal cells","name":"articletitle","label":"Article Title"},{"value":"Journal of Inorganic Biochemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jinorgbio.2016.04.017","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}