{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T00:57:02Z","timestamp":1792803422424,"version":"4.5.0"},"reference-count":43,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,7,1]],"date-time":"2020-07-01T00:00:00Z","timestamp":1593561600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,7,1]],"date-time":"2020-07-01T00:00:00Z","timestamp":1593561600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100004564","name":"Ministry of Education, Science and Technological Development of the Republic of Serbia","doi-asserted-by":"publisher","award":["172016"],"award-info":[{"award-number":["172016"]}],"id":[{"id":"10.13039\/501100004564","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004564","name":"Ministry of Education, Science and Technological Development of the Republic of Serbia","doi-asserted-by":"publisher","award":["172034"],"award-info":[{"award-number":["172034"]}],"id":[{"id":"10.13039\/501100004564","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004564","name":"Ministry of Education, Science and Technological Development of the Republic of Serbia","doi-asserted-by":"publisher","award":["175069"],"award-info":[{"award-number":["175069"]}],"id":[{"id":"10.13039\/501100004564","id-type":"DOI","asserted-by":"publisher"}]},{"name":"bilateral project with PR China"},{"DOI":"10.13039\/501100010301","name":"Faculty of Medical Sciences, University of Kragujevac","doi-asserted-by":"publisher","award":["MP02\/19"],"award-info":[{"award-number":["MP02\/19"]}],"id":[{"id":"10.13039\/501100010301","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006109","name":"VEGA","doi-asserted-by":"publisher","award":["1\/0148\/19"],"award-info":[{"award-number":["1\/0148\/19"]}],"id":[{"id":"10.13039\/501100006109","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005357","name":"APVV","doi-asserted-by":"publisher","award":["APVV-18-0016"],"award-info":[{"award-number":["APVV-18-0016"]}],"id":[{"id":"10.13039\/501100005357","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Inorganic Biochemistry"],"published-print":{"date-parts":[[2020,7]]},"DOI":"10.1016\/j.jinorgbio.2020.111078","type":"journal-article","created":{"date-parts":[[2020,4,29]],"date-time":"2020-04-29T21:07:10Z","timestamp":1588194430000},"page":"111078","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"special_numbering":"C","title":["Synthesis, characterization and cytotoxic activity of binuclear copper(II)-complexes with some S-isoalkyl derivatives of thiosalicylic acid. Crystal structure of the binuclear copper(II)-complex with S-isopropyl derivative of thiosalicylic acid"],"prefix":"10.1016","volume":"208","author":[{"given":"Jelena","family":"Dimitrijevi\u0107","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aleksandar N.","family":"Arsenijevi\u0107","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marija Z.","family":"Milovanovi\u0107","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2107-3490","authenticated-orcid":false,"given":"Neboj\u0161a N.","family":"Arsenijevi\u0107","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jelena Z.","family":"Milovanovi\u0107","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana S.","family":"Stankovi\u0107","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andriana M.","family":"Bukonji\u0107","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Du\u0161an Lj.","family":"Tomovi\u0107","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zoran R.","family":"Ratkovi\u0107","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivan","family":"Poto\u010d\u0148\u00e1k","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erika","family":"Samo\u013eov\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gordana P.","family":"Radi\u0107","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jinorgbio.2020.111078_bb0005","doi-asserted-by":"crossref","first-page":"2451","DOI":"10.1021\/cr980420v","article-title":"Current status of platinum-based antitumor drugs","volume":"99","author":"Wong","year":"1999","journal-title":"Chem. Rev."},{"key":"10.1016\/j.jinorgbio.2020.111078_bb0010","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1007\/s00280-016-2976-z","article-title":"Platinum-based drugs: past, present and future","volume":"77","author":"Dilruba","year":"2016","journal-title":"Cancer Chemother. Pharmacol."},{"key":"10.1016\/j.jinorgbio.2020.111078_bb0015","first-page":"1663","article-title":"Cisplatin and platinum drugs at the molecular level. (Review)","volume":"10","author":"Boulikas","year":"2003","journal-title":"Oncol. Rep."},{"key":"10.1016\/j.jinorgbio.2020.111078_bb0020","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1007\/s00775-011-0847-y","article-title":"Novel palladium(II) complexes containing a sulfur ligand: structure and biological activity on HeLa cells","volume":"17","author":"Gao","year":"2012","journal-title":"J. Biol. Inorg. Chem."},{"issue":"19","key":"10.1016\/j.jinorgbio.2020.111078_bb0025","doi-asserted-by":"crossref","first-page":"6889","DOI":"10.1021\/jm101019j","article-title":"Synthesis and biological activities of transition metal complexes based on acetylsalicylic acid as neo-anticancer agents","volume":"53","author":"Rubner","year":"2010","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.jinorgbio.2020.111078_bb0030","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/S1040-8428(01)00222-0","article-title":"Rhodium and its compounds as potential agents in cancer treatment","volume":"42","author":"Katsaros","year":"2002","journal-title":"Crit. Rev. Oncol. Hematol."},{"key":"10.1016\/j.jinorgbio.2020.111078_bb0035","doi-asserted-by":"crossref","first-page":"4414","DOI":"10.1021\/jo202624s","article-title":"Lewis acid-catalyzed, copper(II)-mediated synthesis of heteroaryl thioethers under base-free conditions","volume":"77","author":"Dai","year":"2012","journal-title":"J. Org. Chem."},{"key":"10.1016\/j.jinorgbio.2020.111078_bb0040","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1080\/00945718608057530","article-title":"Preparation, characterization and antimicrobial activity studies on some ternary complexes of Cu(II) with acetylacetone and various salicylic acids","volume":"16","author":"Anjaneyulu","year":"1986","journal-title":"Synth. React. Inorg. Met. Chem."},{"issue":"4","key":"10.1016\/j.jinorgbio.2020.111078_bb0045","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1002\/med.20174","article-title":"Copper in diseases and treatments, and copper-based anticancer strategies","volume":"30","author":"Tisato","year":"2010","journal-title":"Med. Res. Rev."},{"key":"10.1016\/j.jinorgbio.2020.111078_bb0050","doi-asserted-by":"crossref","first-page":"185","DOI":"10.2174\/187152009787313837","article-title":"Copper complexes as anticancer agents","volume":"9","author":"Marzano","year":"2009","journal-title":"Anti Cancer Agents Med. Chem."},{"key":"10.1016\/j.jinorgbio.2020.111078_bb0055","doi-asserted-by":"crossref","DOI":"10.4061\/2011\/594529","article-title":"Copper and its complexes in medicine: a biochemical approach","volume":"2011","author":"Iakovidis","year":"2011","journal-title":"Mol. Biol. Int."},{"key":"10.1016\/j.jinorgbio.2020.111078_bb0060","series-title":"Advances in Anticancer Agents in Medicinal Chemistry","author":"Prudhomme","year":"2013"},{"key":"10.1016\/j.jinorgbio.2020.111078_bb0065","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1021\/cr400135x","article-title":"Advances in copper complexes as anticancer agents","volume":"114","author":"Santini","year":"2014","journal-title":"Chem. Rev."},{"key":"10.1016\/j.jinorgbio.2020.111078_bb0070","doi-asserted-by":"crossref","first-page":"890","DOI":"10.1002\/zaac.201500049","article-title":"Novel copper(II) thiodibenzoic acid coordination polymers by in situ extrusion of sulfur from 2,2-dithiodibenzoic acid and the unique oxidation of disulfide to sulfate","volume":"641","author":"Moosun","year":"2015","journal-title":"Zeitschrift Fur Anorg. Und Allg. Chemie."},{"key":"10.1016\/j.jinorgbio.2020.111078_bb0075","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.ccr.2016.01.011","article-title":"Coordination chemistry of the thiosalicylate ligand","volume":"313","author":"Wehr-Candler","year":"2016","journal-title":"Coord. Chem. Rev."},{"key":"10.1016\/j.jinorgbio.2020.111078_bb0080","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1007\/BF00807586","article-title":"Complexation equilibria between copper(II) and thiosalicylic acid. Spectrophotometric determination of copper in non-ferrous alloys","volume":"128","author":"Abu-Bakr","year":"1997","journal-title":"Monatshefte Fur Chemie"},{"key":"10.1016\/j.jinorgbio.2020.111078_bb0085","doi-asserted-by":"crossref","first-page":"2153","DOI":"10.1002\/ejic.201301562","article-title":"Supramolecular 3-\/4-mercaptobenzoic acid complexes of palladium(II) and platinum(II) stabilized by hydrogen bonding","author":"Vivekananda","year":"2014","journal-title":"Eur. J. Inorg. Chem."},{"key":"10.1016\/j.jinorgbio.2020.111078_bb0090","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/0162-0134(94)00059-J","article-title":"Synthesis and characterization of polymeric, anionic thiosalicylato-Ag(I) complexes with antimicrobial activities","volume":"58","author":"Nomiya","year":"1995","journal-title":"J. Inorg. Biochem."},{"issue":"4","key":"10.1016\/j.jinorgbio.2020.111078_bb0095","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/0162-0134(95)00028-3","article-title":"Synthesis and characterization of trisodium salt of bis(thiosalicylato)aurate(I): Na3[Au(TSA)2]\u00b75H2O","volume":"60","author":"Nomiya","year":"1995","journal-title":"J. Inorg. Biochem."},{"issue":"1\u20132","key":"10.1016\/j.jinorgbio.2020.111078_bb0100","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/S0020-1693(01)00564-3","article-title":"Copper(II) complexes of new unsymmetrical NSN thioether ligands","volume":"324","author":"Gilbert","year":"2001","journal-title":"Inorg. Chim. Acta"},{"issue":"6","key":"10.1016\/j.jinorgbio.2020.111078_bb0105","first-page":"8454","article-title":"Effects of aspirin on proliferation, invasion and apoptosis of Hep-2 cells via the PTEN\/AKT\/NF-\u03baB\/survivin signaling pathway","volume":"15","author":"Jin","year":"2018","journal-title":"Oncol. Lett."},{"issue":"1","key":"10.1016\/j.jinorgbio.2020.111078_bb0110","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.poly.2011.08.042","article-title":"Synthesis, characterization and antimicrobial activity of palladium(II) complexes with some alkyl derivates of thiosalicylic acids: crystal structure of the bis(S-benzyl-thiosalicylate)-palladium(II) complex, [Pd(S-bz-thiosal)2]","volume":"31","author":"Radi\u0107","year":"2012","journal-title":"Polyhedron"},{"key":"10.1016\/j.jinorgbio.2020.111078_bb0115","author":"CrysAlisPRO"},{"key":"10.1016\/j.jinorgbio.2020.111078_bb0120","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1107\/S2053273314026370","article-title":"SHELXT - integrated space-group and crystal-structure determination","volume":"71","author":"Sheldrick","year":"2015","journal-title":"Acta Cryst. A"},{"key":"10.1016\/j.jinorgbio.2020.111078_bb0125","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1107\/S2053229614024218","article-title":"Crystal structure refinement with SHELXL","volume":"71","author":"Sheldrick","year":"2015","journal-title":"Acta Cryst. C"},{"key":"10.1016\/j.jinorgbio.2020.111078_bb0130","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1107\/S0021889899006020","article-title":"WinGX suite for small-molecule single-crystal crystallography","volume":"32","author":"Farrugia","year":"1999","journal-title":"J. Appl. Crystallogr."},{"key":"10.1016\/j.jinorgbio.2020.111078_bb0135","author":"Brandenburg"},{"issue":"1\u20132","key":"10.1016\/j.jinorgbio.2020.111078_bb0140","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/0022-1759(83)90303-4","article-title":"Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays","volume":"65","author":"Mosmann","year":"1983","journal-title":"J. Immunol. Methods"},{"key":"10.1016\/j.jinorgbio.2020.111078_bb0145","doi-asserted-by":"crossref","first-page":"944","DOI":"10.1016\/j.jinorgbio.2010.04.014","article-title":"Ligand substitution reactions and cytotoxic properties of [Au(L)Cl2]+ and [AuCl2(DMSO)2]+ complexes (L=ethylenediamine and S-methyl-l-cysteine)","volume":"104","author":"Milovanovi\u0107","year":"2010","journal-title":"J. Inorg. Biochem."},{"key":"10.1016\/j.jinorgbio.2020.111078_bb0150","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/S0022-1759(98)00090-8","article-title":"Apoptosis detection by annexin V binding: a novel method for the quantitation of cell-mediated cytotoxicity","volume":"217","author":"Shounan","year":"1998","journal-title":"J. Immunol. Methods"},{"key":"10.1016\/j.jinorgbio.2020.111078_bb0155","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.poly.2014.04.053","article-title":"Synthesis, characterization and antimicrobial activity of copper(II)-complexes with some S-alkyl derivatives of thiosalicylic acid. Crystal structure of the binuclear copper(II)-complex with S-methyl derivative of thiosalicylic acid","volume":"79","author":"Nikoli\u0107","year":"2014","journal-title":"Polyhedron"},{"key":"10.1016\/j.jinorgbio.2020.111078_bb0160","series-title":"Infrared Spectra of Inorganic and Coordination Compounds","author":"Nakamoto","year":"1986"},{"key":"10.1016\/j.jinorgbio.2020.111078_bb0165","series-title":"Spectrometric Identification of Organic Compounds","author":"Silverstein","year":"1974"},{"key":"10.1016\/j.jinorgbio.2020.111078_bb0170","series-title":"Infrared Spectra of Inorganic and Coordination Compounds","author":"Nakamoto","year":"1963"},{"key":"10.1016\/j.jinorgbio.2020.111078_bb0175","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1007\/BF02932132","article-title":"Antimicrobial activity of a series of thiosemicarbazones and their Zn(II) and Pd(II) complexes","volume":"52","author":"Kizilcikli","year":"2007","journal-title":"Folia Microbiol."},{"key":"10.1016\/j.jinorgbio.2020.111078_bb0180","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/0022-1902(61)80475-2","article-title":"The synthesis and infrared absorption spectra of complexes of cobalt with pentadentate propylenediaminetetraacetic acid","volume":"20","author":"Swaminathan","year":"1961","journal-title":"J. Inorg. Nucl. Chem."},{"key":"10.1016\/j.jinorgbio.2020.111078_bb0185","first-page":"23126","article-title":"Coordination environment of copper sites in Cu-CHA zeolite investigated by electron paramagnetic resonance","volume":"118","author":"Godiksen","year":"2014","journal-title":"J. Phys. Chem."},{"key":"10.1016\/j.jinorgbio.2020.111078_bb0190","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1016\/j.poly.2008.12.016","article-title":"Ferromagnetic exchange coupling in a new bis(\u03bc-chloro)-bridged copper(II) Schiff base complex: synthesis, structure, magnetic properties and catalytic oxidation of cycloalkanes","volume":"28","author":"Thakurta","year":"2009","journal-title":"Polyhedron"},{"key":"10.1016\/j.jinorgbio.2020.111078_bb0195","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1016\/j.molstruc.2016.03.058","article-title":"Cytotoxicity of copper(II)-complexes with some S-alkyl derivatives of thiosalicylic acid. Crystal structure of the binuclear copper(II)-complex with S-ethyl derivative of thiosalicylic acid","volume":"1116","author":"Nikoli\u0107","year":"2016","journal-title":"J. Mol. Struct."},{"key":"10.1016\/j.jinorgbio.2020.111078_bb0200","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1107\/S2052520616003954","article-title":"The Cambridge structural database","volume":"72","author":"Groom","year":"2016","journal-title":"Acta Cryst. B"},{"issue":"3","key":"10.1016\/j.jinorgbio.2020.111078_bb0205","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1002\/1097-0142(19930801)72:3<663::AID-CNCR2820720307>3.0.CO;2-V","article-title":"A phase II study of continuous infusion 5-fluorouracil and leucovorin with weekly cisplatin in metastatic colorectal carcinoma","volume":"72","author":"Grem","year":"1993","journal-title":"Cancer"},{"issue":"3","key":"10.1016\/j.jinorgbio.2020.111078_bb0210","doi-asserted-by":"crossref","first-page":"1265","DOI":"10.1038\/bjc.1996.242","article-title":"Phase II study of a short course of weekly high-dose cisplatin combined with long-term oral etoposide in metastatic colorectal cancer","volume":"72","author":"Planting","year":"1996","journal-title":"Br. J. Cancer"},{"key":"10.1016\/j.jinorgbio.2020.111078_bb0215","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1038\/sj.bjc.6603596","article-title":"Ki67 expression levels are a better marker of reduced melanoma growth following MEK inhibitor treatment than phospho-ERK levels","volume":"96","author":"Smalley","year":"2007","journal-title":"Br. J. Cancer"}],"container-title":["Journal of Inorganic Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0162013420301069?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0162013420301069?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T14:59:13Z","timestamp":1758985153000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0162013420301069"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7]]},"references-count":43,"alternative-id":["S0162013420301069"],"URL":"https:\/\/doi.org\/10.1016\/j.jinorgbio.2020.111078","relation":{},"ISSN":["0162-0134"],"issn-type":[{"value":"0162-0134","type":"print"}],"subject":[],"published":{"date-parts":[[2020,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Synthesis, characterization and cytotoxic activity of binuclear copper(II)-complexes with some S-isoalkyl derivatives of thiosalicylic acid. Crystal structure of the binuclear copper(II)-complex with S-isopropyl derivative of thiosalicylic acid","name":"articletitle","label":"Article Title"},{"value":"Journal of Inorganic Biochemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jinorgbio.2020.111078","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"111078"}}