{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T20:33:24Z","timestamp":1790800404541,"version":"4.1.0"},"reference-count":71,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,6,22]],"date-time":"2022-06-22T00:00:00Z","timestamp":1655856000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001321","name":"National Research Foundation","doi-asserted-by":"publisher","award":["129288"],"award-info":[{"award-number":["129288"]}],"id":[{"id":"10.13039\/501100001321","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Inorganic Biochemistry"],"published-print":{"date-parts":[[2022,9]]},"DOI":"10.1016\/j.jinorgbio.2022.111905","type":"journal-article","created":{"date-parts":[[2022,6,16]],"date-time":"2022-06-16T13:11:38Z","timestamp":1655385098000},"page":"111905","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":22,"special_numbering":"C","title":["Rhenium(I) derivatives of aminoquinoline and imidazolopiperidine-based ligands: Synthesis, in vitro and in silico biological evaluation against Plasmodium falciparum"],"prefix":"10.1016","volume":"234","author":[{"given":"Sara Nasiri","family":"Sovari","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taryn M.","family":"Golding","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mziyanda","family":"Mbaba","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roxanne","family":"Mohunlal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy J.","family":"Egan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregory S.","family":"Smith","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabio","family":"Zobi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.jinorgbio.2022.111905_bb0005","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1128\/CMR.17.1.235-254.2004","article-title":"History, dynamics, and public health importance of malaria parasite resistance","volume":"17","author":"Talisuna","year":"2004","journal-title":"Clin. Microbiol. Rev."},{"issue":"3","key":"10.1016\/j.jinorgbio.2022.111905_bb0010","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.parint.2009.04.004","article-title":"Spread and evolution of Plasmodium falciparum drug resistance","volume":"58","author":"Mita","year":"2009","journal-title":"Parasitol. Int."},{"issue":"11","key":"10.1016\/j.jinorgbio.2022.111905_bb0015","doi-asserted-by":"crossref","first-page":"756","DOI":"10.2471\/BLT.21.011121","article-title":"Public health round-up","volume":"99","author":"WHO","year":"2021","journal-title":"Bull. World Health Organ."},{"issue":"21","key":"10.1016\/j.jinorgbio.2022.111905_bb0020","doi-asserted-by":"crossref","first-page":"11865","DOI":"10.1073\/pnas.93.21.11865","article-title":"On the molecular mechanism of chloroquine\u2019s antimalarial action","volume":"93","author":"Sullivan","year":"1996","journal-title":"Proc. Natl. Acad. Sci."},{"issue":"6775","key":"10.1016\/j.jinorgbio.2022.111905_bb0025","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1038\/35005132","article-title":"The structure of malaria pigment \u03b2-haematin","volume":"404","author":"Pagola","year":"2000","journal-title":"Nature"},{"issue":"3","key":"10.1016\/j.jinorgbio.2022.111905_bb0030","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1021\/ja308741e","article-title":"The single crystal X-ray structure of \u03b2-hematin DMSO solvate grown in the presence of chloroquine, a \u03b2-hematin growth-rate inhibitor","volume":"135","author":"Gildenhuys","year":"2013","journal-title":"J. Am. Chem. Soc."},{"issue":"6","key":"10.1016\/j.jinorgbio.2022.111905_bb0035","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1021\/cg025550i","article-title":"Quinoline binding site on malaria pigment crystal: a rational pathway for antimalaria drug design","volume":"2","author":"Buller","year":"2002","journal-title":"Cryst. Growth Des."},{"issue":"16","key":"10.1016\/j.jinorgbio.2022.111905_bb0040","doi-asserted-by":"crossref","first-page":"4946","DOI":"10.1073\/pnas.1501023112","article-title":"Mechanisms of hematin crystallization and inhibition by the antimalarial drug chloroquine","volume":"112","author":"Olafson","year":"2015","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"4934","key":"10.1016\/j.jinorgbio.2022.111905_bb0045","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1038\/202805a0","article-title":"Complex formation between chloroquine and ferrih\u00e6mic acid in vitro, and its effect on the antimalarial action of chloroquine","volume":"202","author":"Cohen","year":"1964","journal-title":"Nature"},{"issue":"5","key":"10.1016\/j.jinorgbio.2022.111905_bb0050","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1128\/AAC.21.5.819","article-title":"Lysis of plasmodium falciparum by ferriprotoporphyrin IX and a chloroquine-ferriprotoporphyrin IX complex","volume":"21","author":"Fitch","year":"1982","journal-title":"Antimicrob. Agents Chemother."},{"issue":"1","key":"10.1016\/j.jinorgbio.2022.111905_bb0055","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1016\/j.jinorgbio.2003.09.007","article-title":"Effects of solvent composition and ionic strength on the interaction of quinoline antimalarials with ferriprotoporphyrin IX","volume":"98","author":"Egan","year":"2004","journal-title":"J. Inorg. Biochem."},{"issue":"38","key":"10.1016\/j.jinorgbio.2022.111905_bb0060","doi-asserted-by":"crossref","first-page":"16767","DOI":"10.1039\/C5DT02671G","article-title":"Alkoxide coordination of iron(iii) protoporphyrin IX by antimalarial quinoline methanols: a key interaction observed in the solid-state and solution","volume":"44","author":"Gildenhuys","year":"2015","journal-title":"Dalton Trans."},{"key":"10.1016\/j.jinorgbio.2022.111905_bb0065","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.jinorgbio.2015.06.010","article-title":"Solution structures of chloroquine-ferriheme complexes modeled using MD simulation and investigated by EXAFS spectroscopy","volume":"154","author":"Kuter","year":"2016","journal-title":"J. Inorg. Biochem."},{"issue":"4","key":"10.1016\/j.jinorgbio.2022.111905_bb0070","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1021\/cb200528z","article-title":"Iron(III) protoporphyrin IX complexes of the antimalarial cinchona alkaloids quinine and quinidine","volume":"7","author":"de Villiers","year":"2012","journal-title":"ACS Chem. Biol."},{"issue":"18","key":"10.1016\/j.jinorgbio.2022.111905_bb0075","doi-asserted-by":"crossref","first-page":"4688","DOI":"10.1111\/j.1742-4658.2007.05999.x","article-title":"Drug-resistant malaria\u2212 an insight","volume":"274","author":"Hyde","year":"2007","journal-title":"FEBS J."},{"key":"10.1016\/j.jinorgbio.2022.111905_bb0080","doi-asserted-by":"crossref","first-page":"9414093","DOI":"10.1155\/2020\/9414093","article-title":"Review of atypical organometallic compounds as antimalarial drugs","volume":"2020","author":"Kwofie","year":"2020","journal-title":"J. Chem."},{"issue":"16","key":"10.1016\/j.jinorgbio.2022.111905_bb0085","doi-asserted-by":"crossref","first-page":"5715","DOI":"10.1021\/om300296n","article-title":"Bioorganometallic compounds with antimalarial targets: inhibiting hemozoin formation","volume":"31","author":"Navarro","year":"2012","journal-title":"Organometallics"},{"issue":"5","key":"10.1016\/j.jinorgbio.2022.111905_bb0090","doi-asserted-by":"crossref","first-page":"3450","DOI":"10.1021\/cr3001252","article-title":"Metalloantimalarials","volume":"113","author":"Salas","year":"2013","journal-title":"Chem. Rev."},{"issue":"40","key":"10.1016\/j.jinorgbio.2022.111905_bb0095","doi-asserted-by":"crossref","first-page":"8676","DOI":"10.1002\/chem.201904699","article-title":"Enhancing the activity of drugs by conjugation to organometallic fragments","volume":"26","author":"Chellan","year":"2020","journal-title":"Chem. Eur. J."},{"key":"10.1016\/j.jinorgbio.2022.111905_bb0100","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejmech.2019.111791","article-title":"Current scenario of ferrocene-containing hybrids for antimalarial activity","volume":"185","author":"Xiao","year":"2020","journal-title":"Eur. J. Med. Chem."},{"issue":"9","key":"10.1016\/j.jinorgbio.2022.111905_bb0105","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1007\/s40265-018-0911-9","article-title":"Drugs in development for malaria","volume":"78","author":"Ashley","year":"2018","journal-title":"Drugs"},{"issue":"9","key":"10.1016\/j.jinorgbio.2022.111905_bb0110","doi-asserted-by":"crossref","first-page":"0066","DOI":"10.1038\/s41570-017-0066","article-title":"The medicinal chemistry of ferrocene and its derivatives","volume":"1","author":"Patra","year":"2017","journal-title":"Nat. Rev. Chem."},{"key":"10.1016\/j.jinorgbio.2022.111905_bb0115","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1016\/j.ejmech.2015.07.009","article-title":"Ferroquine and its derivatives: new generation of antimalarial agents","volume":"101","author":"Wani","year":"2015","journal-title":"Eur. J. Med. Chem."},{"issue":"7","key":"10.1016\/j.jinorgbio.2022.111905_bb0120","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1016\/j.jinorgbio.2011.03.019","article-title":"Synthesis, characterization and antimalarial activity of new chromium arene\u2013quinoline half sandwich complexes","volume":"105","author":"Glans","year":"2011","journal-title":"J. Inorg. Biochem."},{"key":"10.1016\/j.jinorgbio.2022.111905_bb0125","series-title":"Highly potent rhenium(I) tricarbonyl complexes with dual anticancer and anti-angiogenic activity against colorectal carcinoma","author":"Joachim","year":"2020"},{"issue":"10","key":"10.1016\/j.jinorgbio.2022.111905_bb0130","doi-asserted-by":"crossref","first-page":"2180","DOI":"10.1021\/cb500528c","article-title":"Underestimated potential of organometallic rhenium complexes as anticancer agents","volume":"9","author":"Leonidova","year":"2014","journal-title":"ACS Chem. Biol."},{"key":"10.1016\/j.jinorgbio.2022.111905_bb0135","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.jorganchem.2013.07.042","article-title":"Rhenium and technetium based radiopharmaceuticals: development and recent advances","volume":"751","author":"J\u00fcrgens","year":"2014","journal-title":"J. Organomet. Chem."},{"issue":"47","key":"10.1016\/j.jinorgbio.2022.111905_bb0140","doi-asserted-by":"crossref","first-page":"16357","DOI":"10.1039\/C7DT03465B","article-title":"Recent development of luminescent rhenium(I) tricarbonyl polypyridine complexes as cellular imaging reagents, anticancer drugs, and antibacterial agents","volume":"46","author":"Lee","year":"2017","journal-title":"Dalton Trans."},{"key":"10.1016\/j.jinorgbio.2022.111905_bb0145","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2174\/1381612825666190902161400","article-title":"Design of rhenium compounds in targeted anticancer therapeutics","volume":"25","author":"Collery","year":"2019","journal-title":"Curr. Pharm. Des."},{"key":"10.1016\/j.jinorgbio.2022.111905_bb0150","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.ccr.2019.04.014","article-title":"Organometallic and coordination rhenium compounds and their potential in cancer therapy","volume":"393","author":"Bauer","year":"2019","journal-title":"Coord. Chem. Rev."},{"issue":"14","key":"10.1016\/j.jinorgbio.2022.111905_bb0155","doi-asserted-by":"crossref","first-page":"1312","DOI":"10.1002\/ejic.202100031","article-title":"Therapeutic and diagnostic applications of multimetallic rhenium(I) tricarbonyl complexes","volume":"2021","author":"Huang","year":"2021","journal-title":"Eur. J. Inorg. Chem."},{"issue":"30","key":"10.1016\/j.jinorgbio.2022.111905_bb0160","doi-asserted-by":"crossref","first-page":"9934","DOI":"10.1039\/C8DT01858H","article-title":"Anticancer activity of complexes of the third row transition metals, rhenium, osmium, and iridium","volume":"47","author":"Konkankit","year":"2018","journal-title":"Dalton Trans."},{"issue":"18","key":"10.1016\/j.jinorgbio.2022.111905_bb0165","doi-asserted-by":"crossref","first-page":"4176","DOI":"10.3390\/molecules25184176","article-title":"Recent emergence of rhenium(I) tricarbonyl complexes as photosensitisers for cancer therapy","volume":"25","author":"Liew","year":"2020","journal-title":"Molecules"},{"issue":"12","key":"10.1016\/j.jinorgbio.2022.111905_bb0170","doi-asserted-by":"crossref","first-page":"6546","DOI":"10.3390\/ijms22126546","article-title":"Nanoparticles functionalised with re(I) tricarbonyl complexes for cancer theranostics","volume":"22","author":"Mkhatshwa","year":"2021","journal-title":"Int. J. Mol. Sci."},{"issue":"7","key":"10.1016\/j.jinorgbio.2022.111905_bb0175","doi-asserted-by":"crossref","first-page":"1442","DOI":"10.1021\/cb4000844","article-title":"Analysis of the mechanism of action of potent antibacterial hetero-tri-organometallic compounds: a structurally new class of antibiotics","volume":"8","author":"Wenzel","year":"2013","journal-title":"ACS Chem. Biol."},{"issue":"44","key":"10.1016\/j.jinorgbio.2022.111905_bb0180","doi-asserted-by":"crossref","first-page":"15269","DOI":"10.1039\/C7DT02874A","article-title":"Benzannulated re(i)\u2013NHC complexes: synthesis, photophysical properties and antimicrobial activity","volume":"46","author":"Siegmund","year":"2017","journal-title":"Dalton Trans."},{"key":"10.1016\/j.jinorgbio.2022.111905_bb0185","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejmech.2021.113858","article-title":"Combatting AMR: a molecular approach to the discovery of potent and non-toxic rhenium complexes active against C. albicans-MRSA co-infection","volume":"226","author":"Sovari","year":"2021","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.jinorgbio.2022.111905_bb0190","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejmech.2020.112533","article-title":"Design, synthesis and in vivo evaluation of 3-arylcoumarin derivatives of rhenium(I) tricarbonyl complexes as potent antibacterial agents against methicillin-resistant Staphylococcus aureus (MRSA)","volume":"205","author":"Sovari","year":"2020","journal-title":"Eur. J. Med. Chem."},{"issue":"2","key":"10.1016\/j.jinorgbio.2022.111905_bb0195","doi-asserted-by":"crossref","first-page":"418","DOI":"10.3390\/chemistry2020026","article-title":"Recent studies on the antimicrobial activity of transition metal complexes of groups 6\u201312","volume":"2","author":"Nasiri Sovari","year":"2020","journal-title":"Chemistry"},{"issue":"13","key":"10.1016\/j.jinorgbio.2022.111905_bb0200","doi-asserted-by":"crossref","first-page":"2852","DOI":"10.1002\/chem.201904689","article-title":"Light-activated rhenium complexes with dual mode of action against bacteria","volume":"26","author":"Frei","year":"2020","journal-title":"Chem. Eur. J."},{"key":"10.1016\/j.jinorgbio.2022.111905_bb0205","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.jorganchem.2012.08.024","article-title":"Cyrhetrenyl chalcones: synthesis, characterization and antimalarial evaluation","volume":"723","author":"Arancibia","year":"2013","journal-title":"J. Organomet. Chem."},{"issue":"21","key":"10.1016\/j.jinorgbio.2022.111905_bb0210","doi-asserted-by":"crossref","first-page":"6443","DOI":"10.1039\/c2dt30077j","article-title":"Synthesis and biological activity of cymantrene and cyrhetrene 4-aminoquinoline conjugates against malaria, leishmaniasis, and trypanosomiasis","volume":"41","author":"Glans","year":"2012","journal-title":"Dalton Trans."},{"issue":"22","key":"10.1016\/j.jinorgbio.2022.111905_bb0215","doi-asserted-by":"crossref","first-page":"8085","DOI":"10.1016\/j.bmc.2010.09.005","article-title":"Synthesis and antimalarial activities of rhenium bioorganometallics based on the 4-aminoquinoline structure","volume":"18","author":"Arancibia","year":"2010","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.jinorgbio.2022.111905_bb0220","doi-asserted-by":"crossref","DOI":"10.1016\/j.jinorgbio.2020.111328","article-title":"Diversification of quinoline-triazole scaffolds with CORMs: synthesis, in vitro and in silico biological evaluation against Plasmodium falciparum","volume":"215","author":"Ishmail","year":"2021","journal-title":"J. Inorg. Biochem."},{"issue":"9","key":"10.1016\/j.jinorgbio.2022.111905_bb0225","doi-asserted-by":"crossref","first-page":"4244","DOI":"10.1021\/jm300041e","article-title":"Imidazolopiperazines: lead optimization of the second-generation antimalarial agents","volume":"55","author":"Nagle","year":"2012","journal-title":"J. Med. Chem."},{"issue":"12","key":"10.1016\/j.jinorgbio.2022.111905_bb0230","doi-asserted-by":"crossref","DOI":"10.3390\/molecules24122310","article-title":"Antiplasmodial activity and in vivo bio-distribution of chloroquine molecules released with a 4-(4-ethynylphenyl)-triazole moiety from organometallo-cobalamins","volume":"24","author":"Rossier","year":"2019","journal-title":"Molecules"},{"issue":"33","key":"10.1016\/j.jinorgbio.2022.111905_bb0235","doi-asserted-by":"crossref","first-page":"3758","DOI":"10.1002\/ejic.201900568","article-title":"Correlation of MLCTs of group 7 fac-[M(CO)(3)](+) complexes (M = Mn, Re) with bipyridine, pyridinylpyrazine, azopyridine, and pyridin-2-ylmethanimine type ligands for rational photoCORM design","volume":"2019","author":"Kottelat","year":"2019","journal-title":"Eur. J. Inorg. Chem."},{"issue":"1","key":"10.1016\/j.jinorgbio.2022.111905_bb0240","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1080\/14756366.2019.1585835","volume":"34","author":"Aimene","year":"2019","journal-title":"J. Enzyme. Inhib. Med. Chem."},{"issue":"4","key":"10.1016\/j.jinorgbio.2022.111905_bb0245","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1002\/jlcr.3709","article-title":"New (99m) Tc(CO)3 -radiolabeled arylpiperazine pharmacophore as potent 5HT1A serotonin receptor radiotracer: docking studies, chemical synthesis, radiolabeling, and biological evaluation","volume":"62","author":"Erfani","year":"2019","journal-title":"J. Labelled. Comp. Radiopharm."},{"issue":"10","key":"10.1016\/j.jinorgbio.2022.111905_bb0250","doi-asserted-by":"crossref","first-page":"5771","DOI":"10.1021\/acs.inorgchem.7b00393","article-title":"Gauging donor\/acceptor properties and redox stability of chelating click-derived triazoles and triazolylidenes: a case study with rhenium(I) complexes","volume":"56","author":"Suntrup","year":"2017","journal-title":"Inorg. Chem."},{"issue":"5","key":"10.1016\/j.jinorgbio.2022.111905_bb0255","doi-asserted-by":"crossref","first-page":"480","DOI":"10.3390\/pharmaceutics12050480","article-title":"Photoactivatable surface-functionalized diatom microalgae for colorectal cancer targeted delivery and enhanced cytotoxicity of anticancer complexes","volume":"12","author":"Delasoie","year":"2020","journal-title":"Pharmaceutics"},{"issue":"3","key":"10.1016\/j.jinorgbio.2022.111905_bb0260","doi-asserted-by":"crossref","first-page":"285","DOI":"10.2174\/138620710790980496","article-title":"Lipophilic mediated assays for beta-hematin inhibitors","volume":"13","author":"Carter","year":"2010","journal-title":"Comb. Chem. High Throughput Screen."},{"issue":"7","key":"10.1016\/j.jinorgbio.2022.111905_bb0265","doi-asserted-by":"crossref","first-page":"3363","DOI":"10.1128\/AAC.00121-11","article-title":"Use of the NP-40 detergent-mediated assay in discovery of inhibitors of beta-hematin crystallization","volume":"55","author":"Sandlin","year":"2011","journal-title":"Antimicrob. Agents Chemother."},{"issue":"2","key":"10.1016\/j.jinorgbio.2022.111905_bb0270","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1016\/j.ab.2004.11.022","article-title":"A colorimetric high-throughput beta-hematin inhibition screening assay for use in the search for antimalarial compounds","volume":"338","author":"Ncokazi","year":"2005","journal-title":"Anal. Biochem."},{"issue":"6","key":"10.1016\/j.jinorgbio.2022.111905_bb0275","doi-asserted-by":"crossref","first-page":"2032","DOI":"10.1016\/j.bbagen.2014.02.009","article-title":"Malarial hemozoin: from target to tool","volume":"1840","author":"Coronado","year":"2014","journal-title":"Biochim. Biophys. Acta Gen. Subj."},{"issue":"12","key":"10.1016\/j.jinorgbio.2022.111905_bb0280","doi-asserted-by":"crossref","first-page":"1437","DOI":"10.4155\/fmc.13.113","article-title":"Hemozoin and antimalarial drug discovery","volume":"5","author":"Fong","year":"2013","journal-title":"Future Med. Chem."},{"issue":"1","key":"10.1016\/j.jinorgbio.2022.111905_bb0285","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1039\/C9MD00468H","article-title":"Insights into structural and physicochemical properties required for \u03b2-hematin inhibition of privileged triarylimidazoles","volume":"11","author":"Veale","year":"2020","journal-title":"RSC Med. Chem."},{"key":"10.1016\/j.jinorgbio.2022.111905_bb0290","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/j.ejmech.2018.09.060","article-title":"Hemozoin inhibiting 2-phenylbenzimidazoles active against malaria parasites","volume":"159","author":"L\u2019Abbate","year":"2018","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.jinorgbio.2022.111905_bb0295","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejmech.2020.112583","article-title":"Identification of novel potent and non-toxic anticancer, anti-angiogenic and antimetastatic rhenium complexes against colorectal carcinoma","volume":"204","author":"Delasoie","year":"2020","journal-title":"Eur. J. Med. Chem."},{"issue":"4254","key":"10.1016\/j.jinorgbio.2022.111905_bb0300","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1126\/science.781840","article-title":"Human malaria parasites in continuous culture","volume":"193","author":"Trager","year":"1976","journal-title":"Science"},{"issue":"2","key":"10.1016\/j.jinorgbio.2022.111905_bb0305","doi-asserted-by":"crossref","first-page":"205","DOI":"10.4269\/ajtmh.1993.48.205","article-title":"Measurement of the lactate dehydrogenase activity of Plasmodium falciparum as an assessment of parasitemia","volume":"48","author":"Makler","year":"1993","journal-title":"Am. J. Trop. Med. Hyg."},{"issue":"44","key":"10.1016\/j.jinorgbio.2022.111905_bb0310","doi-asserted-by":"crossref","first-page":"6615","DOI":"10.1039\/b810189b","article-title":"Long-range corrected hybrid density functionals with damped atom-atom dispersion corrections","volume":"10","author":"Chai","year":"2008","journal-title":"Phys. Chem. Chem. Phys."},{"issue":"8","key":"10.1016\/j.jinorgbio.2022.111905_bb0315","doi-asserted-by":"crossref","DOI":"10.1063\/1.2834918","article-title":"Systematic optimization of long-range corrected hybrid density functionals","volume":"128","author":"Chai","year":"2008","journal-title":"J. Chem. Phys."},{"issue":"15","key":"10.1016\/j.jinorgbio.2022.111905_bb0320","doi-asserted-by":"crossref","first-page":"1787","DOI":"10.1002\/jcc.20495","article-title":"Semiempirical GGA-type density functional constructed with a long-range dispersion correction","volume":"27","author":"Grimme","year":"2006","journal-title":"J. Comput. Chem."},{"issue":"20","key":"10.1016\/j.jinorgbio.2022.111905_bb0325","doi-asserted-by":"crossref","first-page":"8554","DOI":"10.1063\/1.475007","article-title":"Systematic optimization of exchange-correlation functionals","volume":"107","author":"Becke","year":"1997","journal-title":"J. Chem. Phys."},{"issue":"2","key":"10.1016\/j.jinorgbio.2022.111905_bb0330","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1063\/1.1424928","article-title":"Empirical correction to density functional theory for van der Waals interactions","volume":"116","author":"Wu","year":"2002","journal-title":"J. Chem. Phys."},{"issue":"2","key":"10.1016\/j.jinorgbio.2022.111905_bb0335","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1007\/BF01114537","article-title":"Energy-adjustedab initio pseudopotentials for the second and third row transition elements","volume":"77","author":"Andrae","year":"1990","journal-title":"Theor. Chim. Acta"},{"issue":"18","key":"10.1016\/j.jinorgbio.2022.111905_bb0340","doi-asserted-by":"crossref","first-page":"2643","DOI":"10.1002\/cbic.202000132","article-title":"The in vitro antiplasmodial and antiproliferative activity of new ferrocene-based \u03b1-aminocresols targeting Hemozoin inhibition and DNA interaction","volume":"21","author":"Mbaba","year":"2020","journal-title":"Chembiochem"},{"issue":"9","key":"10.1016\/j.jinorgbio.2022.111905_bb0345","doi-asserted-by":"crossref","first-page":"1891","DOI":"10.1002\/cbdv.201200033","article-title":"Structure of malaria pigment and related propanoate-linked metalloporphyrin dimers","volume":"9","author":"Bohle","year":"2012","journal-title":"Chem. Biodivers."},{"issue":"4","key":"10.1016\/j.jinorgbio.2022.111905_bb0350","doi-asserted-by":"crossref","first-page":"3760","DOI":"10.3390\/molecules18043760","article-title":"Comparing the suitability of autodock, gold and glide for the docking and predicting the possible targets of Ru(II)-based complexes as anticancer agents","volume":"18","author":"Adeniyi","year":"2013","journal-title":"Molecules"},{"key":"10.1016\/j.jinorgbio.2022.111905_bb0355","author":"The Scripps Research Institute"}],"container-title":["Journal of Inorganic Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0162013422001945?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0162013422001945?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T19:58:09Z","timestamp":1777492689000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0162013422001945"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9]]},"references-count":71,"alternative-id":["S0162013422001945"],"URL":"https:\/\/doi.org\/10.1016\/j.jinorgbio.2022.111905","relation":{},"ISSN":["0162-0134"],"issn-type":[{"value":"0162-0134","type":"print"}],"subject":[],"published":{"date-parts":[[2022,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Rhenium(I) derivatives of aminoquinoline and imidazolopiperidine-based ligands: Synthesis, in vitro and in silico biological evaluation against Plasmodium falciparum","name":"articletitle","label":"Article Title"},{"value":"Journal of Inorganic Biochemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jinorgbio.2022.111905","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"111905"}}