{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T23:59:24Z","timestamp":1789516764188,"version":"build-2803163510"},"reference-count":65,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Inorganic Biochemistry"],"published-print":{"date-parts":[[2023,8]]},"DOI":"10.1016\/j.jinorgbio.2023.112239","type":"journal-article","created":{"date-parts":[[2023,4,28]],"date-time":"2023-04-28T11:35:39Z","timestamp":1682681739000},"page":"112239","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"special_numbering":"C","title":["Novel Zn(II)-complex with hybrid chalcone-thiosemicarbazone ligand: Synthesis, characterization, and inhibitory effect on HTLV-1-infected MT-2 leukemia cells"],"prefix":"10.1016","volume":"245","author":[{"given":"Maria Clara","family":"Campos","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Igor Resendes","family":"Barbosa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guilherme Pereira","family":"Guedes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aurea","family":"Echevarria","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juliana","family":"Echevarria-Lima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ot\u00e1vio Augusto","family":"Chaves","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jinorgbio.2023.112239_bb0005","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/j.neurol.2011.12.006","volume":"168","author":"Gessain","year":"2012","journal-title":"Rev. Neurol."},{"key":"10.1016\/j.jinorgbio.2023.112239_bb0010","doi-asserted-by":"crossref","first-page":"7415","DOI":"10.1073\/pnas.77.12.7415","volume":"77","author":"Poisez","year":"1980","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.jinorgbio.2023.112239_bb0015","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/S0140-6736(85)92734-5","volume":"24","author":"Gessain","year":"1985","journal-title":"Lancet"},{"key":"10.1016\/j.jinorgbio.2023.112239_bb0020","doi-asserted-by":"crossref","first-page":"e517","DOI":"10.1016\/S1470-2045(14)70202-5","volume":"15","author":"Ishitsuka","year":"2014","journal-title":"Lancet Oncol."},{"key":"10.1016\/j.jinorgbio.2023.112239_bb0025","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1590\/1806-9282.62.07.691","volume":"62","author":"Oliveira","year":"2016","journal-title":"Rev. Assoc. Med. Bras."},{"key":"10.1016\/j.jinorgbio.2023.112239_bb0030","doi-asserted-by":"crossref","first-page":"5545","DOI":"10.3390\/ijms22115545","volume":"22","author":"Schnell","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.jinorgbio.2023.112239_bb0035","doi-asserted-by":"crossref","first-page":"925","DOI":"10.3389\/fmicb.2018.00925","volume":"9","author":"Marino-Merlo","year":"2018","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.jinorgbio.2023.112239_bb0040","doi-asserted-by":"crossref","first-page":"51981","DOI":"10.18632\/oncotarget.10223","volume":"7","author":"Zell","year":"2016","journal-title":"Oncotarget"},{"key":"10.1016\/j.jinorgbio.2023.112239_bb0045","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.1016\/j.drudis.2020.04.023","volume":"25","author":"Houssein","year":"2020","journal-title":"Drug Discov. Today"},{"key":"10.1016\/j.jinorgbio.2023.112239_bb0050","doi-asserted-by":"crossref","first-page":"2537","DOI":"10.3390\/molecules25112537","volume":"25","author":"Sousa-Pereira","year":"2020","journal-title":"Molecules"},{"key":"10.1016\/j.jinorgbio.2023.112239_bb0055","doi-asserted-by":"crossref","DOI":"10.1016\/j.bmc.2020.115746","volume":"28","author":"dos Santos","year":"2020","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.jinorgbio.2023.112239_bb0060","volume":"8","author":"Mei","year":"2021","journal-title":"Front. Mol. Biosci."},{"key":"10.1016\/j.jinorgbio.2023.112239_bb0065","doi-asserted-by":"crossref","first-page":"933","DOI":"10.3390\/biom12070933","volume":"12","author":"Abate","year":"2022","journal-title":"Biomolecules"},{"key":"10.1016\/j.jinorgbio.2023.112239_bb0070","doi-asserted-by":"crossref","first-page":"16004","DOI":"10.1039\/D0DT02478C","volume":"49","author":"de Paiva","year":"2020","journal-title":"Dalton Trans."},{"key":"10.1016\/j.jinorgbio.2023.112239_bb0075","doi-asserted-by":"crossref","first-page":"4540","DOI":"10.1021\/cr400460s","volume":"114","author":"Mjos","year":"2014","journal-title":"Chem. Rev."},{"key":"10.1016\/j.jinorgbio.2023.112239_bb0080","doi-asserted-by":"crossref","first-page":"8765","DOI":"10.1021\/jm1007616","volume":"53","author":"Pelosi","year":"2010","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.jinorgbio.2023.112239_bb0085","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.3390\/v3071041","volume":"3","author":"Guimaraes-Correa","year":"2011","journal-title":"Viruses"},{"key":"10.1016\/j.jinorgbio.2023.112239_bb0090","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1080\/14756366.2016.1265517","volume":"32","author":"Burmaoglu","year":"2017","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.jinorgbio.2023.112239_bb0095","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.21873\/anticanres.11421","volume":"37","author":"Sakagami","year":"2017","journal-title":"Anticancer Res."},{"key":"10.1016\/j.jinorgbio.2023.112239_bb0100","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.ejmech.2014.09.027","volume":"87","author":"Moreno-Rodr\u00edguez","year":"2014","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.jinorgbio.2023.112239_bb0105","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1080\/1061186X.2020.1853759","volume":"29","author":"Elkhalifa","year":"2021","journal-title":"J. Drug Target."},{"key":"10.1016\/j.jinorgbio.2023.112239_bb0110","doi-asserted-by":"crossref","first-page":"24483","DOI":"10.1039\/D0RA03684F","volume":"10","author":"Fu","year":"2020","journal-title":"RSC Adv."},{"key":"10.1016\/j.jinorgbio.2023.112239_bb0115","doi-asserted-by":"crossref","first-page":"633","DOI":"10.3892\/ijo.2017.4026","volume":"51","author":"Ishikawa","year":"2017","journal-title":"Int. J. Oncol."},{"key":"10.1016\/j.jinorgbio.2023.112239_bb0120","doi-asserted-by":"crossref","first-page":"643","DOI":"10.3390\/biom9110643","volume":"9","author":"Mendes","year":"2019","journal-title":"Biomolecules"},{"key":"10.1016\/j.jinorgbio.2023.112239_bb0125","doi-asserted-by":"crossref","DOI":"10.2174\/1573407218666220111104011","volume":"18","author":"Rodrigues","year":"2022","journal-title":"Curr. Bioac. Compd."},{"key":"10.1016\/j.jinorgbio.2023.112239_bb0130","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1007\/s11243-018-0262-0","volume":"43","author":"Barbosa","year":"2018","journal-title":"Trans. Metal Chem."},{"key":"10.1016\/j.jinorgbio.2023.112239_bb0135","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1107\/S2056989021007398","volume":"77","author":"Tan","year":"2021","journal-title":"Acta Crystallogr. E: Crystallogr. Commun."},{"key":"10.1016\/j.jinorgbio.2023.112239_bb0140","doi-asserted-by":"crossref","first-page":"229","DOI":"10.2478\/s11532-009-0116-x","volume":"8","author":"Muthukumar","year":"2010","journal-title":"Open Chem."},{"key":"10.1016\/j.jinorgbio.2023.112239_bb0145","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1016\/j.ejmech.2013.04.036","volume":"65","author":"da Silva","year":"2013","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.jinorgbio.2023.112239_bb0150","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1080\/00958972.2012.757762","volume":"66","author":"Da Silva","year":"2013","journal-title":"J. Coord. Chem."},{"key":"10.1016\/j.jinorgbio.2023.112239_bb0155","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1007\/s10534-016-9933-5","volume":"29","author":"S\u00e2mia","year":"2016","journal-title":"Biometals"},{"key":"10.1016\/j.jinorgbio.2023.112239_bb0160","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.abb.2016.07.009","volume":"606","author":"Vutey","year":"2016","journal-title":"Arch. Biochem."},{"key":"10.1016\/j.jinorgbio.2023.112239_bb0165","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1016\/j.ejmech.2013.04.036","volume":"65","author":"da Silva","year":"2013","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.jinorgbio.2023.112239_bb0170","series-title":"APEX2","author":"Bruker","year":"2012"},{"key":"10.1016\/j.jinorgbio.2023.112239_bb0175","series-title":"SAINT","author":"Bruker","year":"2012"},{"key":"10.1016\/j.jinorgbio.2023.112239_bb0180","series-title":"SADABS","author":"Bruker","year":"2001"},{"key":"10.1016\/j.jinorgbio.2023.112239_bb0185","first-page":"3","volume":"C71","author":"Sheldrick","year":"2015","journal-title":"Acta Cryst"},{"key":"10.1016\/j.jinorgbio.2023.112239_bb0190","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1107\/S002188980600731X","volume":"39","author":"Macrae","year":"2006","journal-title":"J. Appl. Crystallogr."},{"key":"10.1016\/j.jinorgbio.2023.112239_bb0195","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1186\/s40199-015-0105-x","article-title":"Artemia salina as a model organism in toxicity assessment of nanoparticles","volume":"23","author":"Rajabi","year":"2015","journal-title":"Daru"},{"key":"10.1016\/j.jinorgbio.2023.112239_bb0200","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1038\/294770a0","volume":"294","author":"Miyoshi","year":"1981","journal-title":"Nature"},{"key":"10.1016\/j.jinorgbio.2023.112239_bb0205","first-page":"997","volume":"72","author":"Miyoshi","year":"1981","journal-title":"Gan."},{"key":"10.1016\/j.jinorgbio.2023.112239_bb0210","doi-asserted-by":"crossref","first-page":"2179","DOI":"10.1073\/pnas.78.4.2179","article-title":"Structure of a B-DNA dodecamer: conformation and dynamics","volume":"78","author":"Drew","year":"1981","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.jinorgbio.2023.112239_bb0215","doi-asserted-by":"crossref","DOI":"10.1016\/j.jinorgbio.2022.111854","volume":"233","author":"Martins","year":"2022","journal-title":"J. Inorg. Biochem."},{"key":"10.1016\/j.jinorgbio.2023.112239_bb0220","doi-asserted-by":"crossref","DOI":"10.1016\/j.molstruc.2022.132480","volume":"1256","author":"Siqueira","year":"2022","journal-title":"J. Mol. Struct."},{"key":"10.1016\/j.jinorgbio.2023.112239_bb0225","doi-asserted-by":"crossref","DOI":"10.1016\/j.poly.2021.115608","volume":"212","author":"Siqueira","year":"2022","journal-title":"Polyhedron"},{"key":"10.1016\/j.jinorgbio.2023.112239_bb0230","first-page":"691","volume":"28","author":"Agarwal","year":"2004","journal-title":"Turk. J. Chem."},{"key":"10.1016\/j.jinorgbio.2023.112239_bb0235","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1139\/v67-081","volume":"45","author":"Wiles","year":"1967","journal-title":"Can. J. Chem."},{"key":"10.1016\/j.jinorgbio.2023.112239_bb0240","doi-asserted-by":"crossref","first-page":"2258","DOI":"10.1139\/v67-365","volume":"45","author":"Wiles","year":"1967","journal-title":"Can. J. Chem."},{"key":"10.1016\/j.jinorgbio.2023.112239_bb0245","doi-asserted-by":"crossref","DOI":"10.1016\/j.poly.2022.115724","volume":"217","author":"Aguirre","year":"2022","journal-title":"Polyhedron"},{"key":"10.1016\/j.jinorgbio.2023.112239_bb0250","doi-asserted-by":"crossref","DOI":"10.1016\/j.molstruc.2020.127782","volume":"1207","author":"Afonin","year":"2020","journal-title":"J. Mol. Struct."},{"key":"10.1016\/j.jinorgbio.2023.112239_bb0255","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.chroma.2012.08.007","volume":"1269","author":"Carradori","year":"2012","journal-title":"J. Chrom. A"},{"key":"10.1016\/j.jinorgbio.2023.112239_bb0260","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/S0166-1280(97)00272-8","volume":"451","author":"Ota","year":"1998","journal-title":"J. Mol. Struct."},{"issue":"2015","key":"10.1016\/j.jinorgbio.2023.112239_bb0265","doi-asserted-by":"crossref","first-page":"6974","DOI":"10.1016\/j.bmc.2015.09.036","volume":"23","author":"Parker","year":"2015","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.jinorgbio.2023.112239_bb0270","doi-asserted-by":"crossref","first-page":"2537","DOI":"10.3390\/molecules27082537","volume":"27","author":"Georgiou","year":"2022","journal-title":"Molecules"},{"key":"10.1016\/j.jinorgbio.2023.112239_bb0275","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1080\/10426507.2014.919502","volume":"190","author":"Turkkan","year":"2015","journal-title":"Phosphorus Sulfur Silicon Relat. Elem."},{"key":"10.1016\/j.jinorgbio.2023.112239_bb0280","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1039\/B617136B","author":"Yang","year":"2007","journal-title":"Dalton Trans."},{"key":"10.1016\/j.jinorgbio.2023.112239_bb0285","doi-asserted-by":"crossref","first-page":"4702","DOI":"10.1016\/j.ejmech.2011.07.016","volume":"46","author":"Zhang","year":"2011","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.jinorgbio.2023.112239_bb0290","doi-asserted-by":"crossref","first-page":"1351","DOI":"10.3390\/cancers3011351","volume":"3","author":"Florea","year":"2011","journal-title":"Cancers"},{"key":"10.1016\/j.jinorgbio.2023.112239_bb0295","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1093\/bioinformatics\/bty707","volume":"35","author":"Yang","year":"2019","journal-title":"Bioinformatics"},{"key":"10.1016\/j.jinorgbio.2023.112239_bb0300","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0191838","volume":"13","author":"Lagunin","year":"2018","journal-title":"PLoS One"},{"key":"10.1016\/j.jinorgbio.2023.112239_bb0305","doi-asserted-by":"crossref","first-page":"1409","DOI":"10.1093\/infdis\/169.6.1409","volume":"169","author":"Prince","year":"1994","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.jinorgbio.2023.112239_bb0310","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1172\/JCI27198","volume":"116","author":"Sibon","year":"2006","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.jinorgbio.2023.112239_bb0315","doi-asserted-by":"crossref","first-page":"1166","DOI":"10.1016\/j.imbio.2013.04.002","volume":"218","author":"Novaes","year":"2013","journal-title":"Immunobiology."},{"key":"10.1016\/j.jinorgbio.2023.112239_bb0320","doi-asserted-by":"crossref","first-page":"1351","DOI":"10.1016\/j.biochi.2011.06.007","volume":"93","author":"Sun","year":"2011","journal-title":"Biochimie"},{"key":"10.1016\/j.jinorgbio.2023.112239_bb0325","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1016\/j.ejmech.2013.04.036","volume":"65","author":"da Silva","year":"2013","journal-title":"Eur. J. Med. Chem."}],"container-title":["Journal of Inorganic Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0162013423001216?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0162013423001216?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T15:10:22Z","timestamp":1758985822000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0162013423001216"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8]]},"references-count":65,"alternative-id":["S0162013423001216"],"URL":"https:\/\/doi.org\/10.1016\/j.jinorgbio.2023.112239","relation":{},"ISSN":["0162-0134"],"issn-type":[{"value":"0162-0134","type":"print"}],"subject":[],"published":{"date-parts":[[2023,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Novel Zn(II)-complex with hybrid chalcone-thiosemicarbazone ligand: Synthesis, characterization, and inhibitory effect on HTLV-1-infected MT-2 leukemia cells","name":"articletitle","label":"Article Title"},{"value":"Journal of Inorganic Biochemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jinorgbio.2023.112239","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"112239"}}