{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T04:00:19Z","timestamp":1790654419579,"version":"4.1.0"},"reference-count":31,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,8,6]],"date-time":"2025-08-06T00:00:00Z","timestamp":1754438400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000923","name":"Australian Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000923","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001779","name":"Monash University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001779","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010221","name":"Higher Education Commision, Pakistan","doi-asserted-by":"publisher","award":["RH201207"],"award-info":[{"award-number":["RH201207"]}],"id":[{"id":"10.13039\/501100010221","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010221","name":"Higher Education Commision, Pakistan","doi-asserted-by":"publisher","award":["AJ289"],"award-info":[{"award-number":["AJ289"]}],"id":[{"id":"10.13039\/501100010221","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Inorganic Biochemistry"],"published-print":{"date-parts":[[2025,12]]},"DOI":"10.1016\/j.jinorgbio.2025.113017","type":"journal-article","created":{"date-parts":[[2025,7,31]],"date-time":"2025-07-31T15:50:54Z","timestamp":1753977054000},"page":"113017","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Indeno[1,2-b]-quinoline carboxylic acids and their dimethylgallium(III) complexes: Evaluation of their efficacy as antibacterial agents"],"prefix":"10.1016","volume":"273","author":[{"given":"Sumiyyah","family":"Hameed","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kirralee J.","family":"Burke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebekah N.","family":"Duffin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victoria L.","family":"Blair","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip C.","family":"Andrews","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jinorgbio.2025.113017_bb0005","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2022.130042","article-title":"Global trend of antimicrobial resistance in common bacterial pathogens in response to antibiotic consumption","volume":"442","author":"Hou","year":"2023","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.jinorgbio.2025.113017_bb0010","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1038\/d41586-024-03033-w","article-title":"40 million deaths by 2050: toll of drug-resistant infections to rise by 70%","volume":"633","author":"Naddaf","year":"2024","journal-title":"Nature"},{"key":"10.1016\/j.jinorgbio.2025.113017_bb0015","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/j.tifs.2021.01.012","article-title":"Antibacterial mechanisms and applications of metal-organic frameworks and their derived nanomaterials","volume":"109","author":"Liu","year":"2021","journal-title":"Trends Food Sci. Technol."},{"key":"10.1016\/j.jinorgbio.2025.113017_bb0020","series-title":"Overuse of antibiotics in farming is a major new threat to human health, says UN","author":"Harvey","year":"2025"},{"key":"10.1016\/j.jinorgbio.2025.113017_bb0025","series-title":"WHO updates list of drug-resistant bacteria most threatening to human health","author":"W. H. Organization","year":"2025"},{"key":"10.1016\/j.jinorgbio.2025.113017_bb0030","doi-asserted-by":"crossref","first-page":"421","DOI":"10.3390\/antibiotics11030421","article-title":"Mechanisms of action of carbapenem resistance","volume":"11","author":"Aurilio","year":"2022","journal-title":"Antibiotics"},{"key":"10.1016\/j.jinorgbio.2025.113017_bb0035","series-title":"Lack of new antibiotics threatens global efforts to contain drug-resistant infections","author":"W. H. Organization","year":"2025"},{"key":"10.1016\/j.jinorgbio.2025.113017_bb0040","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1039\/D0CB00218F","article-title":"Brief survey on organometalated antibacterial drugs and metal-based materials with antibacterial activity","volume":"2","author":"Biega\u0144ski","year":"2021","journal-title":"RSC Chem. Biol."},{"key":"10.1016\/j.jinorgbio.2025.113017_bb0045","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1038\/nrmicro3028","article-title":"Antimicrobial activity of metals: mechanisms, molecular targets and applications","volume":"11","author":"Lemire","year":"2013","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.jinorgbio.2025.113017_bb0050","doi-asserted-by":"crossref","first-page":"416","DOI":"10.3390\/bioengineering9090416","article-title":"Gallium-based liquid metal materials for antimicrobial applications","volume":"9","author":"Qu","year":"2022","journal-title":"Bioengineering"},{"key":"10.1016\/j.jinorgbio.2025.113017_bb0055","first-page":"1311","article-title":"Gallium nitrate: the second metal with clinical activity","volume":"70","author":"Foster","year":"1986","journal-title":"Cancer Treat. Rep."},{"key":"10.1016\/j.jinorgbio.2025.113017_bb0060","doi-asserted-by":"crossref","first-page":"2876","DOI":"10.3390\/ijms22062876","article-title":"Recent advances in iron chelation and gallium-based therapies for antibiotic resistant bacterial infections","volume":"22","author":"Vinuesa","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.jinorgbio.2025.113017_bb0065","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1002\/biof.1159","article-title":"Repurposing of gallium-based drugs for antibacterial therapy","volume":"40","author":"Bonchi","year":"2014","journal-title":"Biofactors"},{"key":"10.1016\/j.jinorgbio.2025.113017_bb0070","doi-asserted-by":"crossref","first-page":"1291","DOI":"10.1093\/jac\/dkn422","article-title":"Co-encapsulation of gallium with gentamicin in liposomes enhances antimicrobial activity of gentamicin against Pseudomonas aeruginosa","volume":"62","author":"Halwani","year":"2008","journal-title":"J. Antimicrob. Chemother."},{"key":"10.1016\/j.jinorgbio.2025.113017_bb0075","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1046\/j.1365-2958.1999.01175.x","article-title":"Non-iron metalloporphyrins: potent antibacterial compounds that exploit haem\/Hb uptake systems of pathogenic bacteria","volume":"31","author":"Stojiljkovic","year":"1999","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.jinorgbio.2025.113017_bb0080","doi-asserted-by":"crossref","first-page":"12","DOI":"10.3389\/fcimb.2017.00012","article-title":"Gallium-protoporphyrin IX inhibits Pseudomonas aeruginosa growth by targeting cytochromes","volume":"7","author":"Hijazi","year":"2017","journal-title":"Front. Cell. Infect. Microbiol."},{"key":"10.1016\/j.jinorgbio.2025.113017_bb0085","doi-asserted-by":"crossref","first-page":"7657","DOI":"10.1128\/AAC.01472-15","article-title":"Antimicrobial activity of gallium protoporphyrin IX against Acinetobacter baumannii strains displaying different antibiotic resistance phenotypes","volume":"59","author":"Arivett","year":"2015","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.jinorgbio.2025.113017_bb0090","doi-asserted-by":"crossref","first-page":"11093","DOI":"10.1039\/D3CC02916F","article-title":"Gallium reactivates first and second generation quinolone antibiotics towards drug-resistant Klebsiella pneumoniae","volume":"59","author":"Sultana","year":"2023","journal-title":"Chem. Commun."},{"key":"10.1016\/j.jinorgbio.2025.113017_bb0095","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejmech.2021.113220","article-title":"Synthetic and medicinal perspective of quinolines as antiviral agents","volume":"215","author":"Kaur","year":"2021","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.jinorgbio.2025.113017_bb0100","first-page":"37","article-title":"Quinolines and quinolones as antibacterial, antifungal, anti-virulence, antiviral and anti-parasitic agents, advances in microbiology","volume":"14","author":"Senerovic","year":"2020","journal-title":"J. Infect. Public Health"},{"key":"10.1016\/j.jinorgbio.2025.113017_bb0105","doi-asserted-by":"crossref","first-page":"108708","DOI":"10.1039\/C6RA22693K","article-title":"Synthesis, characterization and biological activity of fluorescently labeled bedaquiline analogues","volume":"6","author":"Rombouts","year":"2016","journal-title":"RSC Adv."},{"key":"10.1016\/j.jinorgbio.2025.113017_bb0110","doi-asserted-by":"crossref","first-page":"2757","DOI":"10.1016\/S0968-0896(01)00109-2","article-title":"QSAR of anticancer compounds. Bis (11-oxo-11H-indeno [1, 2-b] quinoline-6-carboxamides), bis (phenazine-1-carboxamides), and bis (naphthalimides)","volume":"9","author":"Mekapati","year":"2001","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.jinorgbio.2025.113017_bb0115","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1016\/S0968-0896(00)00264-9","article-title":"Positioning of the carboxamide side chain in 11-oxo-11H-indeno [1, 2-b] quinolinecarboxamide anticancer agents: effects on cytotoxicity","volume":"9","author":"Deady","year":"2001","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.jinorgbio.2025.113017_bb0120","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1021\/jm00079a011","article-title":"Synthesis and antibacterial activity of new tetracyclic quinolone antibacterials","volume":"35","author":"Taguchi","year":"1992","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.jinorgbio.2025.113017_bb0125","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/j.jinorgbio.2018.11.017","article-title":"Structure\u2212 activity relationships of 2-quinolinecarboxaldehyde thiosemicarbazone gallium (III) complexes with potent and selective anticancer activity","volume":"191","author":"Cao","year":"2019","journal-title":"J. Inorg. Biochem."},{"key":"10.1016\/j.jinorgbio.2025.113017_bb0130","doi-asserted-by":"crossref","DOI":"10.1016\/j.jinorgbio.2023.112371","article-title":"Enhanced antibacterial activity of dimethyl gallium quinolinolates toward drug-resistant Klebsiella pneumoniae in low iron environments","volume":"249","author":"Duffin","year":"2023","journal-title":"J. Inorg. Biochem."},{"key":"10.1016\/j.jinorgbio.2025.113017_bb0135","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1007\/s00706-012-0822-5","article-title":"A simple one-pot synthesis of quinoline-4-carboxylic acid derivatives by Pfitzinger reaction of isatin with ketones in water","volume":"144","author":"Lv","year":"2013","journal-title":"Monatsh. Chem."},{"key":"10.1016\/j.jinorgbio.2025.113017_bb0140","first-page":"2586","article-title":"Ueber Aminoverbindungen des \u03b2-Naphthols","volume":"44","author":"Noelting","year":"1911","journal-title":"Ber. Dtsch. Chem. Ges."},{"key":"10.1016\/j.jinorgbio.2025.113017_bb0145","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/S0010-8545(00)80455-5","article-title":"Relationships between the carbon-oxygen stretching frequencies of carboxylato complexes and the type of carboxylate coordination","volume":"33","author":"Deacon","year":"1980","journal-title":"Coord. Chem. Rev."},{"key":"10.1016\/j.jinorgbio.2025.113017_bb0150","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejmech.2019.111895","article-title":"Alkyl gallium (III) quinolinolates: a new class of highly selective anti-leishmanial agents","volume":"186","author":"Duffin","year":"2020","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.jinorgbio.2025.113017_bb0155","doi-asserted-by":"crossref","first-page":"316","DOI":"10.3389\/fcimb.2018.00316","article-title":"Antimicrobial activity of gallium compounds on ESKAPE pathogens","volume":"8","author":"Hijazi","year":"2018","journal-title":"Front. Cell. Infect. Microbiol."}],"container-title":["Journal of Inorganic Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0162013425001977?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0162013425001977?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T10:53:59Z","timestamp":1772794439000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0162013425001977"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12]]},"references-count":31,"alternative-id":["S0162013425001977"],"URL":"https:\/\/doi.org\/10.1016\/j.jinorgbio.2025.113017","relation":{},"ISSN":["0162-0134"],"issn-type":[{"value":"0162-0134","type":"print"}],"subject":[],"published":{"date-parts":[[2025,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Indeno[1,2-b]-quinoline carboxylic acids and their dimethylgallium(III) complexes: Evaluation of their efficacy as antibacterial agents","name":"articletitle","label":"Article Title"},{"value":"Journal of Inorganic Biochemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jinorgbio.2025.113017","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"113017"}}