{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T01:05:04Z","timestamp":1788915904696,"version":"build-2803163510"},"reference-count":143,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,8,14]],"date-time":"2025-08-14T00:00:00Z","timestamp":1755129600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["AI55912"],"award-info":[{"award-number":["AI55912"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["AI102883"],"award-info":[{"award-number":["AI102883"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["AI134886"],"award-info":[{"award-number":["AI134886"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Inorganic Biochemistry"],"published-print":{"date-parts":[[2025,12]]},"DOI":"10.1016\/j.jinorgbio.2025.113023","type":"journal-article","created":{"date-parts":[[2025,8,8]],"date-time":"2025-08-08T01:58:41Z","timestamp":1754618321000},"page":"113023","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Mechanisms of bacterial heme uptake and degradation: Diverse strategies for ring opening"],"prefix":"10.1016","volume":"273","author":[{"given":"Kieran","family":"Johnson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fengtian","family":"Xue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela","family":"Wilks","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jinorgbio.2025.113023_bb0005","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/S0162-0134(02)00461-0","volume":"91","author":"Crichton","year":"2002","journal-title":"J. Inorg. Biochem."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0010","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/S0968-0004(99)01359-6","volume":"24","author":"Braun","year":"1999","journal-title":"Trends Biochem. Sci."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0015","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/bs.ampbs.2021.07.004","volume":"79","author":"Mourino","year":"2021","journal-title":"Adv. Microb. Physiol."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0020","doi-asserted-by":"crossref","DOI":"10.1093\/mtomcs\/mfae052","volume":"16","author":"Egan","year":"2024","journal-title":"Metallomics"},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0025","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1038\/s41579-024-01090-6","volume":"23","author":"Schalk","year":"2025","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0030","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1146\/annurev.biochem.77.061606.161055","volume":"77","author":"Imlay","year":"2008","journal-title":"Annu. Rev. Biochem."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0035","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1126\/science.2834821","volume":"240","author":"Imlay","year":"1988","journal-title":"Science"},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0040","doi-asserted-by":"crossref","first-page":"217","DOI":"10.3109\/10408419209114559","volume":"18","author":"Otto","year":"1992","journal-title":"Crit. Rev. Microbiol."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0045","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1146\/annurev.micro.54.1.881","volume":"54","author":"Ratledge","year":"2000","journal-title":"Ann. Rev. Microbiol."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0050","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.coi.2009.01.011","volume":"21","author":"Ganz","year":"2009","journal-title":"Curr. Opin. Immunol."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0055","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1038\/s41579-022-00745-6","article-title":"Nutritional immunity: the battle for nutrient metals at the host\u2013pathogen interface","volume":"20","author":"Murdoch","year":"2022","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0060","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1146\/annurev-genet-120215-035146","volume":"50","author":"Palmer","year":"2016","journal-title":"Annu. Rev. Genet."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0065","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1111\/1462-2920.16328","volume":"25","author":"Schalk","year":"2023","journal-title":"Environ. Microbiol."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0070","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1016\/j.jinorgbio.2007.11.017","volume":"102","author":"Schalk","year":"2008","journal-title":"J. Inorg. Biochem."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0075","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1007\/BF01141174","volume":"3","author":"Royt","year":"1990","journal-title":"Biol. Met."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0080","doi-asserted-by":"crossref","first-page":"3680","DOI":"10.1128\/iai.59.10.3680-3684.1991","volume":"59","author":"Heinrichs","year":"1991","journal-title":"Infect. Immun."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0085","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1111\/j.1432-1033.1990.tb19094.x","volume":"191","author":"Konetschny-Rapp","year":"1990","journal-title":"Eur. J. Biochem."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0090","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1007\/BF00205858","volume":"6","author":"Drechsel","year":"1993","journal-title":"Biometals"},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0095","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1128\/jb.150.2.490-497.1982","volume":"150","author":"Van Tiel-Menkveld","year":"1982","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0100","doi-asserted-by":"crossref","first-page":"4189","DOI":"10.1128\/aem.59.12.4189-4197.1993","volume":"59","author":"Loper","year":"1993","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0105","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1007\/s10534-006-0003-2","volume":"19","author":"Cartron","year":"2006","journal-title":"Biometals"},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0110","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1039\/C8MT00097B","volume":"10","author":"Sestok","year":"2018","journal-title":"Metallomics"},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0115","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.cbpa.2013.12.014","volume":"19","author":"Contreras","year":"2014","journal-title":"Curr. Opin. Chem. Biol."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0120","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1146\/annurev-biochem-060815-014214","volume":"86","author":"Huang","year":"2017","journal-title":"Annu. Rev. Biochem."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0125","doi-asserted-by":"crossref","first-page":"32138","DOI":"10.1074\/jbc.M109.040915","volume":"284","author":"Fabian","year":"2009","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0130","doi-asserted-by":"crossref","first-page":"8479","DOI":"10.1074\/jbc.M112.430009","volume":"288","author":"Honsa","year":"2013","journal-title":"J. Biol. Chem."},{"issue":"Pt 1","key":"10.1016\/j.jinorgbio.2025.113023_bb0135","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1099\/00221287-146-1-185","article-title":"Genetics and regulation of two distinct haem-uptake systems, phu and has, in Pseudomonas aeruginosa The GenBank accession numbers for the sequences reported in this paper are AF055999, AF127222, and AF127223","volume":"146","author":"Ochsner","year":"2000","journal-title":"Microbiology"},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0140","doi-asserted-by":"crossref","first-page":"7756","DOI":"10.1074\/jbc.M114.633495","volume":"290","author":"Smith","year":"2015","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0145","doi-asserted-by":"crossref","first-page":"10456","DOI":"10.1074\/jbc.RA120.014081","volume":"295","author":"Dent","year":"2020","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0150","doi-asserted-by":"crossref","DOI":"10.1128\/mBio.00966-14","volume":"5","author":"Marvig","year":"2014","journal-title":"MBio"},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0155","doi-asserted-by":"crossref","first-page":"2265","DOI":"10.1128\/JB.01491-14","volume":"196","author":"Nguyen","year":"2014","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0160","doi-asserted-by":"crossref","first-page":"2601","DOI":"10.1021\/acs.biochem.5b00017","volume":"54","author":"Smith","year":"2015","journal-title":"Biochemistry"},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0165","doi-asserted-by":"crossref","first-page":"26932","DOI":"10.1074\/jbc.M112.366385","volume":"287","author":"Caillet-Saguy","year":"2012","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0170","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1073\/pnas.0809406106","volume":"106","author":"Krieg","year":"2009","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0175","doi-asserted-by":"crossref","first-page":"35796","DOI":"10.1074\/jbc.M706761200","volume":"282","author":"Ho","year":"2007","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0180","doi-asserted-by":"crossref","first-page":"1794","DOI":"10.1021\/cb400165b","volume":"8","author":"O'Neill","year":"2013","journal-title":"ACS Chem. Biol."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0185","doi-asserted-by":"crossref","first-page":"6394","DOI":"10.1128\/JB.183.21.6394-6403.2001","volume":"183","author":"Ratliff","year":"2001","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0190","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1046\/j.1365-2958.1997.2501619.x","volume":"23","author":"Lewis","year":"1997","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0195","doi-asserted-by":"crossref","first-page":"6043","DOI":"10.1128\/JB.180.22.6043-6047.1998","volume":"180","author":"Lewis","year":"1998","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0200","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1046\/j.1365-2958.2002.02745.x","volume":"43","author":"Rohde","year":"2002","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0205","doi-asserted-by":"crossref","first-page":"2771","DOI":"10.1074\/jbc.RA118.006185","volume":"294","author":"Dent","year":"2019","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0210","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1021\/bi801860g","volume":"48","author":"Alontaga","year":"2009","journal-title":"Biochemistry"},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0215","doi-asserted-by":"crossref","first-page":"9857","DOI":"10.1021\/ja103498z","volume":"132","author":"Jepkorir","year":"2010","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0220","doi-asserted-by":"crossref","first-page":"6646","DOI":"10.1021\/bi100692f","volume":"49","author":"Yukl","year":"2010","journal-title":"Biochemistry"},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0225","doi-asserted-by":"crossref","first-page":"2549","DOI":"10.1021\/acs.biochem.1c00389","volume":"60","author":"Dent","year":"2021","journal-title":"Biochemistry"},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0230","doi-asserted-by":"crossref","first-page":"1741","DOI":"10.1128\/IAI.74.3.1741-1744.2006","volume":"74","author":"Brickman","year":"2006","journal-title":"Infect. Immun."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0235","doi-asserted-by":"crossref","first-page":"4278","DOI":"10.1128\/JB.183.14.4278-4287.2001","volume":"183","author":"Vanderpool","year":"2001","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0240","doi-asserted-by":"crossref","first-page":"3004","DOI":"10.1128\/jb.177.11.3004-3009.1995","volume":"177","author":"Mills","year":"1995","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0245","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1046\/j.1365-2958.1997.2641628.x","volume":"23","author":"Torres","year":"1997","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0250","doi-asserted-by":"crossref","first-page":"3269","DOI":"10.1128\/jb.176.11.3269-3277.1994","volume":"176","author":"Henderson","year":"1994","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0255","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1046\/j.1365-2958.2001.02683.x","volume":"42","author":"Mey","year":"2001","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0260","doi-asserted-by":"crossref","first-page":"5358","DOI":"10.1128\/iai.65.12.5358-5363.1997","volume":"65","author":"Mills","year":"1997","journal-title":"Infect. Immun."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0265","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1111\/j.1365-2958.2008.06509.x","article-title":"Haem acquisition is facilitated by a novel receptor Hma and required by uropathogenic Escherichia coli for kidney infection","volume":"71","author":"Hagan","year":"2009","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0270","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1021\/acs.biochem.6b01099","volume":"56","author":"LaMattina","year":"2017","journal-title":"Biochemistry"},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0275","doi-asserted-by":"crossref","first-page":"12138","DOI":"10.1073\/pnas.1603209113","volume":"113","author":"LaMattina","year":"2016","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0280","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1093\/femsre\/fuv009","volume":"39","author":"Sheldon","year":"2015","journal-title":"FEMS Microbiol. Rev."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0285","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1039\/c1mt00047k","volume":"3","author":"Nobles","year":"2011","journal-title":"Metallomics"},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0290","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1000132","volume":"4","author":"Maresso","year":"2008","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0295","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1128\/JB.188.3.1071-1080.2006","volume":"188","author":"Skaar","year":"2006","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0300","doi-asserted-by":"crossref","first-page":"1042","DOI":"10.1128\/IAI.71.3.1042-1055.2003","volume":"71","author":"Bates","year":"2003","journal-title":"Infect. Immun."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0305","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.abb.2013.08.009","volume":"538","author":"Ouattara","year":"2013","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0310","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1111\/j.1365-2958.2005.05015.x","article-title":"Iron acquisition systems for ferric hydroxamates, haemin and haemoglobin in Listeria monocytogenes","volume":"59","author":"Jin","year":"2006","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0315","doi-asserted-by":"crossref","first-page":"69","DOI":"10.3109\/09687688.2012.694485","volume":"29","author":"Klebba","year":"2012","journal-title":"Mol. Membr. Biol."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0320","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1007\/s10534-019-00188-2","volume":"32","author":"Conroy","year":"2019","journal-title":"Biometals"},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0325","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/j.jinorgbio.2009.09.012","article-title":"Structural biology of heme binding in the Staphylococcus aureus Isd system","volume":"104","author":"Grigg","year":"2010","journal-title":"J. Inorg. Biochem."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0330","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1126\/science.285.5428.760","volume":"285","author":"Mazmanian","year":"1999","journal-title":"Science"},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0335","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1126\/science.1081147","volume":"299","author":"Mazmanian","year":"2003","journal-title":"Science"},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0340","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1016\/j.jmb.2011.08.047","article-title":"Iron-Coordinating Tyrosine Is a Key Determinant of NEAT Domain Heme Transfer","volume":"413","author":"Grigg","year":"2011","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0345","doi-asserted-by":"crossref","first-page":"1529","DOI":"10.1111\/j.1365-2958.2010.07076.x","volume":"75","author":"Reniere","year":"2010","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0350","doi-asserted-by":"crossref","first-page":"4260","DOI":"10.1038\/s41467-019-12109-5","volume":"10","author":"Mitra","year":"2019","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0355","doi-asserted-by":"crossref","first-page":"5051","DOI":"10.1073\/pnas.1009516108","volume":"108","author":"Tullius","year":"2011","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0360","doi-asserted-by":"crossref","first-page":"1518","DOI":"10.1021\/bi2018305","volume":"51","author":"Owens","year":"2012","journal-title":"Biochemistry"},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0365","doi-asserted-by":"crossref","first-page":"21714","DOI":"10.1074\/jbc.M113.453076","volume":"288","author":"Owens","year":"2013","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0370","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1007\/s00203-017-1434-6","volume":"200","author":"Sandhu","year":"2018","journal-title":"Arch. Microbiol."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0375","doi-asserted-by":"crossref","DOI":"10.1128\/mBio.01720-16","volume":"8","author":"Mitra","year":"2017","journal-title":"mBio"},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0380","doi-asserted-by":"crossref","first-page":"e0360422","DOI":"10.1128\/spectrum.03604-22","volume":"10","author":"Donegan","year":"2022","journal-title":"Microbiol. Spectr."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0385","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.abb.2013.10.013","volume":"544","author":"Wilks","year":"2014","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0390","doi-asserted-by":"crossref","first-page":"2291","DOI":"10.1021\/ar500028n","volume":"47","author":"Wilks","year":"2014","journal-title":"Acc. Chem. Res."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0395","doi-asserted-by":"crossref","DOI":"10.1016\/j.jinorgbio.2021.111636","volume":"226","author":"Brimberry","year":"2022","journal-title":"J. Inorg. Biochem."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0400","doi-asserted-by":"crossref","first-page":"4641","DOI":"10.1021\/acs.biochem.9b00841","volume":"58","author":"Mathew","year":"2019","journal-title":"Biochemistry"},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0405","doi-asserted-by":"crossref","first-page":"860","DOI":"10.1038\/12319","volume":"6","author":"Schuller","year":"1999","journal-title":"Nat. Struct. Biol."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0410","doi-asserted-by":"crossref","first-page":"11552","DOI":"10.1021\/bi0110239","volume":"40","author":"Schuller","year":"2001","journal-title":"Biochemistry"},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0415","doi-asserted-by":"crossref","first-page":"5239","DOI":"10.1021\/bi049687g","volume":"43","author":"Friedman","year":"2004","journal-title":"Biochemistry"},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0420","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1021\/ar9001685","volume":"43","author":"Matsui","year":"2010","journal-title":"Acc. Chem. Res."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0425","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1089\/15230860260220102","volume":"4","author":"Wilks","year":"2002","journal-title":"Antioxid. Redox Signal."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0430","doi-asserted-by":"crossref","first-page":"6002","DOI":"10.1021\/ja00127a013","volume":"117","author":"Takahashi","year":"1995","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0435","doi-asserted-by":"crossref","first-page":"21055","DOI":"10.1074\/jbc.M400491200","volume":"279","author":"Unno","year":"2004","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0440","doi-asserted-by":"crossref","first-page":"29553","DOI":"10.1016\/S0021-9258(18)43915-4","volume":"269","author":"Wilks","year":"1994","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0445","doi-asserted-by":"crossref","first-page":"1798","DOI":"10.1021\/ja0122391","volume":"124","author":"Davydov","year":"2002","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0450","doi-asserted-by":"crossref","first-page":"16208","DOI":"10.1021\/ja038923s","volume":"125","author":"Davydov","year":"2003","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0455","doi-asserted-by":"crossref","first-page":"11842","DOI":"10.1021\/ja036147i","volume":"125","author":"Caignan","year":"2003","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0460","doi-asserted-by":"crossref","first-page":"6077","DOI":"10.1021\/ja017334o","article-title":"Models of the Low-Spin Iron(III) Hydroperoxide Intermediate of Heme Oxygenase:Magnetic Resonance Evidence for Thermodynamic Stabilization of the dxy Electronic State at Ambient Temperatures","volume":"124","author":"Rivera","year":"2002","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0465","doi-asserted-by":"crossref","first-page":"11730","DOI":"10.1021\/ja072405q","volume":"129","author":"Rodriguez","year":"2007","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0470","doi-asserted-by":"crossref","first-page":"22357","DOI":"10.1016\/S0021-9258(18)41536-0","volume":"268","author":"Wilks","year":"1993","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0475","doi-asserted-by":"crossref","first-page":"6909","DOI":"10.1074\/jbc.272.11.6909","volume":"272","author":"Liu","year":"1997","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0480","doi-asserted-by":"crossref","first-page":"5297","DOI":"10.1074\/jbc.275.8.5297","volume":"275","author":"Liu","year":"2000","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0485","doi-asserted-by":"crossref","first-page":"6618","DOI":"10.1074\/jbc.271.12.6618","volume":"271","author":"Matera","year":"1996","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0490","doi-asserted-by":"crossref","first-page":"30957","DOI":"10.1074\/jbc.M709486200","article-title":"Ruffling of Metalloporphyrins Bound to IsdG and IsdI, Two Heme-degrading Enzymes in Staphylococcus aureus","volume":"283","author":"Lee","year":"2008","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0495","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1016\/j.jmb.2009.11.025","volume":"395","author":"Chim","year":"2010","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0500","doi-asserted-by":"crossref","first-page":"5931","DOI":"10.1021\/ic500033b","volume":"53","author":"Graves","year":"2014","journal-title":"Inorg. Chem."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0505","doi-asserted-by":"crossref","first-page":"34179","DOI":"10.1074\/jbc.M112.393249","volume":"287","author":"Ukpabi","year":"2012","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0510","doi-asserted-by":"crossref","first-page":"13071","DOI":"10.1073\/pnas.1101459108","volume":"108","author":"Takayama","year":"2011","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0515","doi-asserted-by":"crossref","first-page":"15455","DOI":"10.1021\/acs.inorgchem.9b02530","volume":"58","author":"Conger","year":"2019","journal-title":"Inorg. Chem."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0520","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1007\/s00775-015-1263-5","volume":"20","author":"Lockhart","year":"2015","journal-title":"J. Biol. Inorg. Chem."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0525","doi-asserted-by":"crossref","first-page":"10058","DOI":"10.1039\/C6DT00702C","volume":"45","author":"Graves","year":"2016","journal-title":"Dalton Trans."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0530","doi-asserted-by":"crossref","DOI":"10.1016\/j.jinorgbio.2022.111775","volume":"230","author":"Schuelke-Sanchez","year":"2022","journal-title":"J. Inorg. Biochem."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0535","doi-asserted-by":"crossref","DOI":"10.1016\/j.jbc.2023.104648","volume":"299","author":"Matsui","year":"2023","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0540","doi-asserted-by":"crossref","first-page":"25749","DOI":"10.1074\/jbc.M113.470518","article-title":"IruO Is a Reductase for Heme Degradation by IsdI and IsdG Proteins in Staphylococcus aureus","volume":"288","author":"Loutet","year":"2013","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0545","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1021\/acs.biochem.0c00950","volume":"60","author":"Brimberry","year":"2021","journal-title":"Biochemistry"},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0550","doi-asserted-by":"crossref","DOI":"10.3390\/antiox11030555","article-title":"Heme Oxygenase-1: An Anti-Inflammatory Effector in Cardiovascular, Lung, and Related Metabolic Disorders","volume":"11","author":"Ryter","year":"2022","journal-title":"Antioxidants"},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0555","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1038\/74680","volume":"6","author":"Otterbein","year":"2000","journal-title":"Nat. Med."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0560","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1038\/nrd3228","volume":"9","author":"Motterlini","year":"2010","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0565","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1089\/152308602753666361","volume":"4","author":"Otterbein","year":"2002","journal-title":"Antioxid. Redox Signal."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0570","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.freeradbiomed.2023.07.015","volume":"207","author":"Mancuso","year":"2023","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0575","doi-asserted-by":"crossref","DOI":"10.3390\/antiox14020187","article-title":"The Heme Oxygenase\/Biliverdin Reductase System and Its Genetic Variants in Physiology and Diseases","volume":"14","author":"Mancuso","year":"2025","journal-title":"Antioxidants"},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0580","first-page":"841","volume":"6","author":"Stocker","year":"2004","journal-title":"Antioxid. Redox Signal."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0585","doi-asserted-by":"crossref","first-page":"57","DOI":"10.3109\/10715768909073428","volume":"6","author":"Stocker","year":"1989","journal-title":"Free Radic. Res. Commun."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0590","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1126\/science.3029864","volume":"235","author":"Stocker","year":"1987","journal-title":"Science"},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0595","doi-asserted-by":"crossref","first-page":"3621","DOI":"10.1073\/pnas.1222375110","volume":"110","author":"Duanmu","year":"2013","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0600","doi-asserted-by":"crossref","first-page":"2711","DOI":"10.1105\/tpc.17.00149","volume":"29","author":"Wittkopp","year":"2017","journal-title":"Plant Cell"},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0605","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1038\/414776a","volume":"414","author":"Bhoo","year":"2001","journal-title":"Nature"},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0610","doi-asserted-by":"crossref","first-page":"45791","DOI":"10.1074\/jbc.M408303200","volume":"279","author":"Wegele","year":"2004","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0615","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1111\/j.1574-6968.2007.01058.x","volume":"280","author":"Barkovits","year":"2008","journal-title":"FEMS Microbiol. Lett."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0620","doi-asserted-by":"crossref","first-page":"1651","DOI":"10.1099\/mic.0.049007-0","volume":"157","author":"Barkovits","year":"2011","journal-title":"Microbiology (Reading)"},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0625","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pbio.3000579","volume":"17","author":"Mukherjee","year":"2019","journal-title":"PLoS Biol."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0630","doi-asserted-by":"crossref","first-page":"20503","DOI":"10.1074\/jbc.M116.728527","volume":"291","author":"Mourino","year":"2016","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0635","doi-asserted-by":"crossref","DOI":"10.1128\/mbio.02763-23","volume":"15","author":"Shahzad","year":"2024","journal-title":"mBio"},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0640","doi-asserted-by":"crossref","DOI":"10.1016\/j.jinorgbio.2024.112576","volume":"257","author":"Apiche","year":"2024","journal-title":"J. Inorg. Biochem."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0645","doi-asserted-by":"crossref","first-page":"11568","DOI":"10.1073\/pnas.0705054104","article-title":"Mycobacterium tuberculosis DosS is a redox sensor and DosT is a hypoxia sensor","volume":"104","author":"Kumar","year":"2007","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0650","doi-asserted-by":"crossref","first-page":"259","DOI":"10.3390\/bios3030259","volume":"3","author":"Sivaramakrishnan","year":"2013","journal-title":"Biosensors (Basel)"},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0655","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1099\/mic.0.023911-0","volume":"155","author":"Nobre","year":"2009","journal-title":"Microbiology (Reading)"},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0660","doi-asserted-by":"crossref","first-page":"4303","DOI":"10.1128\/AAC.00802-07","volume":"51","author":"Nobre","year":"2007","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0665","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1016\/j.redox.2018.02.001","volume":"15","author":"Imber","year":"2018","journal-title":"Redox Biol."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0670","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2012.00030","article-title":"Direct Antioxidant Properties of Bilirubin and Biliverdin. Is there a Role for Biliverdin Reductase?","volume":"3","author":"Jansen","year":"2012","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0675","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2012.00047","article-title":"Go Green: The Anti-Inflammatory Effects of Biliverdin Reductase","volume":"3","author":"Wegiel","year":"2012","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0680","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1038\/s41564-023-01549-x","volume":"9","author":"Hall","year":"2024","journal-title":"Nat. Microbiol."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0685","doi-asserted-by":"crossref","first-page":"3324","DOI":"10.1021\/acs.jproteome.5c00059","volume":"24","author":"Busch","year":"2025","journal-title":"J. Proteome Res."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0690","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1128\/iai.36.1.17-23.1982","volume":"36","author":"Cox","year":"1982","journal-title":"Infect. Immun."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0695","doi-asserted-by":"crossref","first-page":"1834","DOI":"10.1128\/IAI.68.4.1834-1839.2000","volume":"68","author":"Takase","year":"2000","journal-title":"Infect. Immun."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0700","doi-asserted-by":"crossref","DOI":"10.1016\/j.micpath.2023.106307","volume":"183","author":"Mathur","year":"2023","journal-title":"Microb. Pathog."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0705","doi-asserted-by":"crossref","first-page":"1637","DOI":"10.1021\/acschembio.9b00373","volume":"14","author":"Shisaka","year":"2019","journal-title":"ACS Chem. Biol."},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0710","doi-asserted-by":"crossref","first-page":"2073","DOI":"10.1021\/acsinfecdis.0c00138","volume":"6","author":"Centola","year":"2020","journal-title":"ACS Infect Dis"},{"key":"10.1016\/j.jinorgbio.2025.113023_bb0715","doi-asserted-by":"crossref","first-page":"1863","DOI":"10.1039\/d0mt00206b","volume":"12","author":"Centola","year":"2020","journal-title":"Metallomics"}],"container-title":["Journal of Inorganic Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S016201342500203X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S016201342500203X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T16:26:11Z","timestamp":1761841571000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S016201342500203X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12]]},"references-count":143,"alternative-id":["S016201342500203X"],"URL":"https:\/\/doi.org\/10.1016\/j.jinorgbio.2025.113023","relation":{},"ISSN":["0162-0134"],"issn-type":[{"value":"0162-0134","type":"print"}],"subject":[],"published":{"date-parts":[[2025,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Mechanisms of bacterial heme uptake and degradation: Diverse strategies for ring opening","name":"articletitle","label":"Article Title"},{"value":"Journal of Inorganic Biochemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jinorgbio.2025.113023","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"113023"}}