{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T08:51:53Z","timestamp":1782118313813,"version":"3.54.5"},"reference-count":79,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100004564","name":"Republic of Serbia Ministry of Education Science and Technological Development","doi-asserted-by":"publisher","award":["451-03-137\/2025-03\/200122"],"award-info":[{"award-number":["451-03-137\/2025-03\/200122"]}],"id":[{"id":"10.13039\/501100004564","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004564","name":"Republic of Serbia Ministry of Education Science and Technological Development","doi-asserted-by":"publisher","award":["451-03-136\/2025-03\/200122"],"award-info":[{"award-number":["451-03-136\/2025-03\/200122"]}],"id":[{"id":"10.13039\/501100004564","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004564","name":"Republic of Serbia Ministry of Education Science and Technological Development","doi-asserted-by":"publisher","award":["451-03-137\/2025-03\/200111"],"award-info":[{"award-number":["451-03-137\/2025-03\/200111"]}],"id":[{"id":"10.13039\/501100004564","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004564","name":"Republic of Serbia Ministry of Education Science and Technological Development","doi-asserted-by":"publisher","award":["451-03-136\/2025-03\/200111"],"award-info":[{"award-number":["451-03-136\/2025-03\/200111"]}],"id":[{"id":"10.13039\/501100004564","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004564","name":"Republic of Serbia Ministry of Education Science and Technological Development","doi-asserted-by":"publisher","award":["451-03-136\/2025-03\/200378"],"award-info":[{"award-number":["451-03-136\/2025-03\/200378"]}],"id":[{"id":"10.13039\/501100004564","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100031403","name":"University of Kragujevac","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100031403","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004329","name":"Slovenian Research and Innovation Agency","doi-asserted-by":"publisher","award":["P1-0175"],"award-info":[{"award-number":["P1-0175"]}],"id":[{"id":"10.13039\/501100004329","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100018992","name":"Serbian Academy of Sciences and Arts","doi-asserted-by":"publisher","award":["F128"],"award-info":[{"award-number":["F128"]}],"id":[{"id":"10.13039\/501100018992","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100017498","name":"Institut \"Jo\u017eef Stefan\"","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100017498","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007657","name":"Univerza v Ljubljani","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007657","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000921","name":"European Cooperation in Science and Technology","doi-asserted-by":"publisher","award":["CA21145"],"award-info":[{"award-number":["CA21145"]}],"id":[{"id":"10.13039\/501100000921","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Inorganic Biochemistry"],"published-print":{"date-parts":[[2026,4]]},"DOI":"10.1016\/j.jinorgbio.2025.113208","type":"journal-article","created":{"date-parts":[[2025,12,30]],"date-time":"2025-12-30T07:39:38Z","timestamp":1767080378000},"page":"113208","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Multimodal anticancer potential of newly synthesized palladium(II), platinum(II), and gold(III) complexes with 2-(Thiazol-2-yl)pyridine-4,5-dicarboxylate dimethyl ester"],"prefix":"10.1016","volume":"277","author":[{"given":"Tina P.","family":"Andrejevi\u0107","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jakob","family":"Kljun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanja","family":"Mati\u0107","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tijana","family":"Markovi\u0107","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u017diko","family":"Milanovi\u0107","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristina","family":"Milisavljevi\u0107","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Darko P.","family":"A\u0161anin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suzana","family":"Popovi\u0107","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dejan","family":"Baski\u0107","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iztok","family":"Turel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Milo\u0161 I.","family":"Djuran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Biljana \u0110.","family":"Gli\u0161i\u0107","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jinorgbio.2025.113208_bb0005","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1126\/science.1083004","article-title":"Boon and bane of metal ions in medicine","volume":"300","author":"Thompson","year":"2003","journal-title":"Science"},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0010","series-title":"Bioinorganic Medicinal Chemistry","author":"Farrer","year":"2011"},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0015","doi-asserted-by":"crossref","first-page":"794","DOI":"10.2174\/1568009614666141128105146","article-title":"Interactions of cisplatin with non-DNA targets and their influence on anticancer activity and drug toxicity: the complex world of the platinum complex","volume":"14","author":"Mezencev","year":"2014","journal-title":"Curr. Cancer Drug Targets"},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0020","doi-asserted-by":"crossref","first-page":"4167","DOI":"10.1002\/ejic.201500754","article-title":"Cytotoxicity and structural analyses of 2,2\u2032-bipyridine-, 4,4\u2032-dimethyl-2,2\u2032-bipyridine- and 2-(2\u2032-pyridyl)quinoxalineplatinum(II) complexes","volume":"2015","author":"Pages","year":"2015","journal-title":"Eur. J. Inorg. Chem."},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0025","doi-asserted-by":"crossref","first-page":"1163","DOI":"10.1016\/j.bmc.2009.12.047","article-title":"Novel 4,4\u2032-diether-2,2\u2032-bipyridine cisplatin analogues are more effective than cisplatin at inducing apoptosis in cancer cell lines","volume":"18","author":"Vo","year":"2010","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0030","doi-asserted-by":"crossref","first-page":"8692","DOI":"10.1016\/j.bmc.2006.08.016","article-title":"A fluorine containing bipyridine cisplatin analog is more effective than cisplatin at inducing apoptosis in cancer cell lines","volume":"14","author":"Elwell","year":"2006","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0035","doi-asserted-by":"crossref","first-page":"1337","DOI":"10.2174\/092986706776872970","article-title":"Platinum group antitumor chemistry: design and development of new anticancer drugs complementary to cisplatin","volume":"13","author":"Abu-Surrah","year":"2006","journal-title":"Curr. Med. Chem."},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0040","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1007\/s13738-015-0804-8","article-title":"Palladium complexes: new candidates for anti-cancer drugs","volume":"13","author":"Jahromi","year":"2016","journal-title":"J. Iran. Chem. Soc."},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0045","series-title":"The Chemistry of Gold (Topics in Inorganic & General Chemistry)","author":"Puddephatt","year":"1978"},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0050","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/S0162-0134(96)00190-0","article-title":"Biological properties of two gold (III) complexes: AuCl3(Hpm) and AuCl2(pm)","volume":"66","author":"Calamai","year":"1997","journal-title":"J. Inorg. Biochem."},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0055","doi-asserted-by":"crossref","first-page":"3541","DOI":"10.1021\/jm990492u","article-title":"Gold(III) complexes as potential antitumor agents: solution chemistry and cytotoxic properties of some selected gold(III) compounds","volume":"43","author":"Messori","year":"2000","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0060","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1007\/BF03215296","article-title":"Gold(III) compounds as anticancer drugs","volume":"40","author":"Gabbiani","year":"2007","journal-title":"Gold Bull."},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0065","doi-asserted-by":"crossref","first-page":"79147","DOI":"10.1039\/C6RA11606J","article-title":"Toward anticancer gold-based compounds targeting PARP-1: a new case study","volume":"6","author":"Citta","year":"2016","journal-title":"RSC Adv."},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0070","doi-asserted-by":"crossref","first-page":"6084","DOI":"10.1039\/D0DT00518E","article-title":"Silver(I) complexes with different pyridine-4,5-dicarboxylate ligands as efficient agents for the control of cow mastitis associated pathogens","volume":"49","author":"Andrejevi\u0107","year":"2020","journal-title":"Dalton Trans."},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0075","doi-asserted-by":"crossref","first-page":"2627","DOI":"10.1039\/D0DT04061D","article-title":"Tailoring copper(II) complexes with pyridine-4,5-dicarboxylate esters for anti-Candida activity","volume":"50","author":"Andrejevi\u0107","year":"2021","journal-title":"Dalton Trans"},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0080","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/j.cbi.2014.11.005","article-title":"Ruthenium complexes as inhibitors of the aldo\u2013keto reductases AKR1C1\u20131C3","volume":"234","author":"Traven","year":"2015","journal-title":"Chem. Biol. Interact."},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0085","doi-asserted-by":"crossref","first-page":"44601","DOI":"10.1021\/acsomega.4c07117","article-title":"Structural and solution speciation studies on fac-tricarbonylrhenium(I) complexes of 2,2\u2032-bipyridine analogues","volume":"9","author":"Pivarcsik","year":"2024","journal-title":"ACS Omega"},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0090","doi-asserted-by":"crossref","first-page":"4719","DOI":"10.1016\/j.tet.2012.04.013","article-title":"A simple metal-free synthesis of 2-substituted pyridine-4,5-dicarboxylates and their N-oxides","volume":"68","author":"Bezen\u0161ek","year":"2012","journal-title":"Tetrahedron"},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0095","doi-asserted-by":"crossref","first-page":"2093","DOI":"10.1039\/C8DT04960B","article-title":"Revisiting the reactivity of tetrachloroauric acid with N,N-bidentate ligands: structural and spectroscopic insights","volume":"48","author":"Mertens","year":"2019","journal-title":"Dalton Trans."},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0100","series-title":"CrysAlis PRO","author":"Oxford Diffraction Ltd","year":"2011"},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0105","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1107\/S0021889808042726","article-title":"OLEX2: a complete structure solution, refinement and analysis program","volume":"42","author":"Dolomanov","year":"2009","journal-title":"J. Appl. Crystallogr."},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0110","series-title":"Shelxl 2018\/3, Program for Crystal Structure Refinement","author":"Sheldrick","year":"2018"},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0115","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1107\/S002188980600731X","article-title":"Mercury: visualization and analysis of crystal structures","volume":"39","author":"Macrae","year":"2006","journal-title":"J. Appl. Crystallogr."},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0120","unstructured":"M.J. Frisch, G.W. Trucks, H.B. Schlegel, G.E. Scuseria, M.A. Robb, J.R. Cheeseman, G. Scalmani, V. Barone, B. Mennucci, G.A. Petersson, H. Nakatsuji, M. Caricato, X. Li, H.P. Hratchian, A.F. Izmaylov, J. Bloino, G. Zheng, J.L. Sonnenberg, M. Hada, M. Ehara, K. Toyota, R. Fukuda, J. Hasegawa, M. Ishida, T. Nakajima, Y. Honda, O. Kitao, H. Nakai, T. Vreven, J.A. Montgomery, Jr., J.E. Peralta, F. Ogliaro, M. Bearpark, J.J. Heyd, E. Brothers, K.N. Kudin, V.N. Staroverov, T. Keith, R. Kobayashi, J. Normand, K. Raghavachari, A. Rendell, J.C. Burant, S.S. Iyengar, J. Tomasi, M. Cossi, N. Rega, J.M. Millam, M. Klene, J.E. Knox, J.B. Cross, V. Bakken, C. Adamo, J. Jaramillo, R. Gomperts, R.E. Stratmann, O. Yazyev, A.J. Austin, R. Cammi, C. Pomelli, J.W. Ochterski, R.L. Martin, K. Morokuma, V.G. Zakrzewski, G.A. Voth, P. Salvador, J.J. Dannenberg, S. Dapprich, A.D. Daniels, O. Farkas, J.B. Foresman, J.V. Ortiz, J. Cioslowski, D.J. Fox, Gaussian, Inc., Wallingford CT (2013)."},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0125","doi-asserted-by":"crossref","DOI":"10.1063\/1.2065267","article-title":"A density-functional model of the dispersion interaction","volume":"123","author":"Becke","year":"2005","journal-title":"J. Chem. Phys."},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0130","doi-asserted-by":"crossref","first-page":"6378","DOI":"10.1021\/jp810292n","article-title":"Universal solvation model based on solute electron density and on a continuum model of the solvent defined by the bulk dielectric constant and atomic surface tensions","volume":"113","author":"Marenich","year":"2009","journal-title":"J. Phys. Chem. B"},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0135","first-page":"157","article-title":"Application of Dft B3Lyp\/Giao and B3Lyp\/Csgt methods for interpretation of NMR spectra of flavonoids","volume":"12","author":"Zieli\u0144ski","year":"2003","journal-title":"Pol. J. Food Nutr. Sci."},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0140","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1063\/1.474464","article-title":"Natural chemical shielding analysis of nuclear magnetic resonance shielding tensors from gauge-including atomic orbital calculations","volume":"107","author":"Bohmann","year":"1997","journal-title":"J. Chem. Phys."},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0145","doi-asserted-by":"crossref","first-page":"1278","DOI":"10.1107\/S0907444912027047","article-title":"Structures of bovine, equine and leporine serum albumin","volume":"D68","author":"Bujacz","year":"2012","journal-title":"Biol. Cryst."},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0150","doi-asserted-by":"crossref","first-page":"2179","DOI":"10.1073\/pnas.78.4.2179","article-title":"Structure of a B-DNA dodecamer: conformation and dynamics","volume":"78","author":"Drew","year":"1981","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0155","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1107\/S0907444905015404","article-title":"The anticancer agent ellipticine unwinds DNA by intercalative binding in an orientation parallel to base pairs","volume":"D61","author":"Canals","year":"2005","journal-title":"Biol. Cryst."},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0160","series-title":"Discovery Studio (Version 2024.1)","author":"Dassault Syst\u00e8mes BIOVIA","year":"2024"},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0165","doi-asserted-by":"crossref","first-page":"1639","DOI":"10.1002\/(SICI)1096-987X(19981115)19:14<1639::AID-JCC10>3.0.CO;2-B","article-title":"Automated docking using a Lamarckian genetic algorithm and an empirical binding free energy function","volume":"19","author":"Morris","year":"1998","journal-title":"J. Comput. Chem."},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0170","doi-asserted-by":"crossref","first-page":"1911","DOI":"10.1002\/jcc.21478","article-title":"A new Lamarckian genetic algorithm for flexible ligand-receptor docking","volume":"31","author":"Fuhrmann","year":"2010","journal-title":"J. Comput. Chem."},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0175","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.ijbiomac.2007.08.010","article-title":"Studies on the interaction of isoxazolcurcumin with calf thymus DNA","volume":"42","author":"Bera","year":"2008","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0180","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1021\/ic501855k","article-title":"Syntheses, structures, and antimicrobial activity of new remarkably light-stable and water-soluble tris(pyrazolyl)methanesulfonate silver(I) derivatives of N-methyl-1,3,5-triaza-7-phosphaadamantane salt - [mPTA]BF4","volume":"54","author":"Smole\u0144ski","year":"2015","journal-title":"Inorg. Chem."},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0185","doi-asserted-by":"crossref","first-page":"6392","DOI":"10.1021\/bi00394a013","article-title":"Polycyclic aromatic hydrocarbons physically intercalate into duplex regions of denatured DNA","volume":"26","author":"Wolfe","year":"1987","journal-title":"Biochem"},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0190","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/0022-1759(83)90303-4","article-title":"Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays","volume":"65","author":"Mosmann","year":"1983","journal-title":"J. Immunol. Methods"},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0195","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1107\/S2052520616003954","article-title":"The Cambridge structural database","volume":"72","author":"Groom","year":"2016","journal-title":"Acta Crystallogr. Sect. B: Struct. Sci. Cryst. Eng. Mater."},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0200","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1021\/ic50085a022","article-title":"Spectroscopic studies of alkyl sulfoxide complexes of platinum(II) and palladium(II)","volume":"9","author":"Kitching","year":"1970","journal-title":"Inorg. Chem."},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0205","doi-asserted-by":"crossref","first-page":"3109","DOI":"10.1016\/j.ica.2009.02.009","article-title":"Synthesis and characterization of gold(III) complexes with alkyldiamine ligands","volume":"362","author":"Al-Maythalony","year":"2009","journal-title":"Inorg. Chim. Acta"},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0210","doi-asserted-by":"crossref","first-page":"902","DOI":"10.1016\/j.saa.2015.06.027","article-title":"Molecular structure, IR spectra, and chemical reactivity of cisplatin and transplatin: DFT studies, basis set effect and solvent effect","volume":"150","author":"Wang","year":"2015","journal-title":"Spectrochim. Acta A Mol. Biomol. Spectrosc."},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0215","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.jinorgbio.2016.11.003","article-title":"Synthesis of Ag(I) camphor sulphonylimine complexes and assessment of their cytotoxic properties against cisplatin-resistant A2780cisR and A2780 cell lines","volume":"166","author":"Cardoso","year":"2017","journal-title":"J. Inorg. Biochem."},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0220","doi-asserted-by":"crossref","first-page":"9326","DOI":"10.1021\/acs.inorgchem.9b01031","article-title":"Cyclometalated gold(III) complexes bearing DACH ligands","volume":"58","author":"Gukathasan","year":"2019","journal-title":"Inorg. Chem."},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0225","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jphotobiol.2013.03.013","article-title":"Drug\u2013DNA interactions and their study by UV\u2013visible, fluorescence spectroscopies and cyclic voltametry","volume":"124","author":"Sirajuddin","year":"2013","journal-title":"J. Photochem. Photobiol. B Biol."},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0230","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/0022-2836(87)90123-9","article-title":"Binding of Hoechst 33258 to the minor groove of B-DNA","volume":"197","author":"Pjura","year":"1987","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0235","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1007\/s00775-021-01879-3","article-title":"Bis(triazinyl)pyridine complexes of Pt(II) and Pd(II): studies of the nucleophilic substitution reactions, DNA\/HSA interactions, molecular docking and biological activity","volume":"26","author":"Jovanovi\u0107-Stevi\u0107","year":"2021","journal-title":"J. Biol. Inorg. Chem."},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0240","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1016\/j.jpha.2019.03.007","article-title":"Interaction of repaglinide with bovine serum albumin: spectroscopic and molecular docking approaches","volume":"9","author":"Pawar","year":"2019","journal-title":"J. Pharm. Anal."},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0245","doi-asserted-by":"crossref","first-page":"303","DOI":"10.3390\/cimb47050303","article-title":"Albumin: a review of market trends, purification methods, and biomedical innovations","volume":"47","author":"Ashraf","year":"2025","journal-title":"Curr. Issues Mol. Biol."},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0250","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/j.saa.2012.11.034","article-title":"Intermolecular interaction of prednisolone with bovine serum albumin: spectroscopic and molecular docking methods","volume":"103","author":"Shi","year":"2013","journal-title":"Spectrochim. Acta A Mol. Biomol. Spectrosc."},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0255","first-page":"1454","article-title":"Study on the binding of 2,3-diazabicyclo[2.2.2]oct-2-ene with bovine serum albumin by fluorescence spectroscopy","volume":"128","author":"Anbazhagan","year":"2008","journal-title":"JOL"},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0260","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1016\/j.ica.2017.02.027","article-title":"Synthesis and characterization of two new trans palladium(II) complexes containing benzylamine ligand: DNA\/BSA interactions, molecular docking and in vitro cytotoxic activity","volume":"471","author":"Karami","year":"2018","journal-title":"Inorg. Chim. Acta"},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0265","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1021\/bm101414w","article-title":"Interaction between DNA and microcystin-LR studied by spectra analysis and atomic force microscopy","volume":"12","author":"Shi","year":"2011","journal-title":"Biomacromolecules"},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0270","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1007\/s10534-016-9984-7","article-title":"Four mononuclear platinum(II) complexes: synthesis, DNA\/BSA binding, DNA cleavage and cytotoxicity","volume":"30","author":"Wang","year":"2017","journal-title":"BioMetals"},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0275","doi-asserted-by":"crossref","first-page":"2211","DOI":"10.1080\/07391102.2016.1213663","article-title":"In vitro study on binding interaction of quinapril with bovine serum albumin (BSA) using multi-spectroscopic and molecular docking methods","volume":"35","author":"Shi","year":"2017","journal-title":"J. Biomol. Struct. Dyn."},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0280","doi-asserted-by":"crossref","first-page":"11172","DOI":"10.1039\/D0NJ02037K","article-title":"Studies of the stability, nucleophilic substitution reactions, DNA\/BSA interactions, cytotoxic activity, DFT and molecular docking of some tetra- and penta-coordinated gold(III) complexes","volume":"44","author":"Radisavljevi\u0107","year":"2020","journal-title":"New J. Chem."},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0285","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1038\/358209a0","article-title":"Atomic structure and chemistry of human serum albumin","volume":"358","author":"He","year":"1992","journal-title":"Nature"},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0290","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1111\/j.1423-0410.2002.tb05326.x","article-title":"Beyond expansion: structural studies on the transport roles of human serum albumin","volume":"83","author":"Curry","year":"2002","journal-title":"Vox Sang."},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0295","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1007\/s10895-019-02383-3","article-title":"Probing the interaction of newly synthesized Pt(II) complex on human serum albumin using competitive binding site markers","volume":"29","author":"Najaran","year":"2019","journal-title":"J. Fluoresc."},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0300","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1007\/s13404-024-00344-8","article-title":"New dinuclear gold(III) complex with 1,5-naphthyridine as bridging ligand: synthesis, characterization, DNA\/BSA binding studies, and anticancer activity","volume":"57","author":"Radisavljevi\u0107","year":"2024","journal-title":"Gold Bull."},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0305","doi-asserted-by":"crossref","first-page":"1970","DOI":"10.1039\/C7MD00381A","article-title":"A systematic analysis of atomic protein\u2013ligand interactions in the PDB","volume":"8","author":"de Freitas","year":"2017","journal-title":"Med. Chem. Commun."},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0310","doi-asserted-by":"crossref","first-page":"1210","DOI":"10.1002\/anie.200390319","article-title":"Interactions with aromatic rings in chemical and biological recognition","volume":"42","author":"Meyer","year":"2003","journal-title":"Angew. Chem. Int. Ed."},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0315","doi-asserted-by":"crossref","first-page":"5061","DOI":"10.1021\/jm100112j","article-title":"A medicinal chemist's guide to molecular interactions","volume":"53","author":"Bissantz","year":"2010","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0320","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1021\/ja0105212","article-title":"Origin of attraction and directionality of the \u03c0\/\u03c0 interaction: model chemistry calculations of benzene dimer interaction","volume":"124","author":"Tsuzuki","year":"2002","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0325","doi-asserted-by":"crossref","first-page":"2100","DOI":"10.1021\/cr300222d","article-title":"Cation\u2212\u03c0 interaction: its role and relevance in chemistry, biology, and material science","volume":"113","author":"Mahadevi","year":"2013","journal-title":"Chem. Rev."},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0330","doi-asserted-by":"crossref","first-page":"9459","DOI":"10.1073\/pnas.96.17.9459","article-title":"Cation-\u03c0 interactions in structural biology","volume":"96","author":"Gallivan","year":"1999","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0335","doi-asserted-by":"crossref","DOI":"10.1038\/cddis.2012.184","article-title":"Chemotherapeutic induction of mitochondrial oxidative stress activates GSK-3\u03b1\/\u03b2 and Bax, leading to permeability transition pore opening and tumor cell death","volume":"3","author":"Chiara","year":"2012","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0340","doi-asserted-by":"crossref","first-page":"871","DOI":"10.3390\/biomedicines9080871","article-title":"Au2phen and Auoxo6, two dinuclear oxo-bridged gold(III) compounds, induce apoptotic signaling in human ovarian A2780 cancer cells","volume":"9","author":"Gorini","year":"2021","journal-title":"Biomedicines"},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0345","doi-asserted-by":"crossref","first-page":"1306","DOI":"10.1016\/j.jinorgbio.2011.06.004","article-title":"Iminophosphorane\u2013organogold(III) complexes induce cell death through mitochondrial ROS production","volume":"105","author":"Vela","year":"2011","journal-title":"J. Inorg. Biochem."},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0350","doi-asserted-by":"crossref","first-page":"3478","DOI":"10.1021\/acs.jmedchem.7b01694","article-title":"Organometallic gold(III) complexes similar to tetrahydroisoquinoline induce ER-stress-mediated apoptosis and pro-death autophagy in A549 cancer cells","volume":"61","author":"Huang","year":"2018","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0355","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejmech.2021.113404","article-title":"Square planar Au(III), Pt(II) and Cu(II) complexes with quinoline-substituted 2,2\u2032:6\u2032,2\u2033-terpyridine ligands: from in vitro to in vivo biological properties","volume":"218","author":"Choroba","year":"2021","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0360","doi-asserted-by":"crossref","first-page":"3632","DOI":"10.1021\/acs.molpharmaceut.3c00239","article-title":"Encapsulation of Au(III) complex using lactoferrin nanoparticles to combat glioma","volume":"20","author":"Zhang","year":"2023","journal-title":"Mol. Pharm."},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0365","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.jinorgbio.2017.08.024","article-title":"In vitro anticancer activity of new gold(III) porphyrin complexes in colon cancer cells","volume":"177","author":"Dandash","year":"2017","journal-title":"J. Inorg. Biochem."},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0370","first-page":"566","article-title":"An indolocarbazole inhibitor of human checkpoint kinase (Chk1) abrogates cell-cycle arrest caused by DNA damage","volume":"60","author":"Jackson","year":"2000","journal-title":"Cancer Res."},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0375","first-page":"5843","article-title":"Abrogation of the Chk1 mediated G2 checkpoint pathway potentiates temozolomide-induced toxicity in a p53-independent manner in human glioblastoma cells","volume":"61","author":"Hirose","year":"2001","journal-title":"Cancer Res."},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0380","first-page":"1590","article-title":"A phase II trial of the cyclin-dependent kinase inhibitor flavopiridol in patients with previously untreated stage IV non-small cell lung cancer","volume":"7","author":"Shapiro","year":"2001","journal-title":"Clin. Cancer Res."},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0385","first-page":"3512","article-title":"Silibinin strongly synergizes human prostate cancer DU145 cells to doxorubicin-induced growth inhibition, G2-M arrest, and apoptosis","volume":"8","author":"Tyagi","year":"2002","journal-title":"Clin. Cancer Res."},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0390","doi-asserted-by":"crossref","first-page":"28042","DOI":"10.18632\/oncotarget.25556","article-title":"Antiproliferative effects of two gold(I)-N-heterocyclic carbene complexes in A2780 human ovarian cancer cells: a comparative proteomic study","volume":"9","author":"Magherini","year":"2018","journal-title":"Oncotarget"},{"key":"10.1016\/j.jinorgbio.2025.113208_bb0395","doi-asserted-by":"crossref","first-page":"1649","DOI":"10.1016\/j.ccr.2009.01.032","article-title":"The tumor proteasome as a novel target for gold(III) complexes: implications for breast cancer therapy","volume":"253","author":"Milacic","year":"2009","journal-title":"Coord. Chem. Rev."}],"container-title":["Journal of Inorganic Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0162013425003897?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0162013425003897?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T08:34:54Z","timestamp":1782117294000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0162013425003897"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":79,"alternative-id":["S0162013425003897"],"URL":"https:\/\/doi.org\/10.1016\/j.jinorgbio.2025.113208","relation":{},"ISSN":["0162-0134"],"issn-type":[{"value":"0162-0134","type":"print"}],"subject":[],"published":{"date-parts":[[2026,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Multimodal anticancer potential of newly synthesized palladium(II), platinum(II), and gold(III) complexes with 2-(Thiazol-2-yl)pyridine-4,5-dicarboxylate dimethyl ester","name":"articletitle","label":"Article Title"},{"value":"Journal of Inorganic Biochemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jinorgbio.2025.113208","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"113208"}}