{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,7]],"date-time":"2026-11-07T05:32:36Z","timestamp":1794029556952,"version":"4.8.0"},"reference-count":61,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2028,2,12]],"date-time":"2028-02-12T00:00:00Z","timestamp":1833926400000},"content-version":"am","delay-in-days":652,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001700","name":"Government of Japan Ministry of Education Culture Sports Science and Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["JP20K05533"],"award-info":[{"award-number":["JP20K05533"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["JP22K05144"],"award-info":[{"award-number":["JP22K05144"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Inorganic Biochemistry"],"published-print":{"date-parts":[[2026,5]]},"DOI":"10.1016\/j.jinorgbio.2026.113258","type":"journal-article","created":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T07:52:50Z","timestamp":1770364370000},"page":"113258","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Pt(II) and Pd(II) complexes bearing 1,10-phenanthroline-based ligands: Distinct binding modes to DNA and anticancer activities"],"prefix":"10.1016","volume":"278","author":[{"given":"Misaki","family":"Nakai","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yusuke","family":"Tsutsumi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Togo","family":"Imai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatsuo","family":"Yajima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazune","family":"Sano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuo","family":"Nagaoka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shigenobu","family":"Yano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hitoshi","family":"Ishida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jinorgbio.2026.113258_bb0005","doi-asserted-by":"crossref","first-page":"1351","DOI":"10.3390\/cancers3011351","volume":"3","author":"Florea","year":"2011","journal-title":"Cancers"},{"key":"10.1016\/j.jinorgbio.2026.113258_bb0010","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1016\/S0021-9258(17)42175-2","volume":"269","author":"Chu","year":"1994","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.jinorgbio.2026.113258_bb0015","doi-asserted-by":"crossref","first-page":"6163","DOI":"10.1073\/pnas.95.11.6163","volume":"95","author":"Zamble","year":"1998","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.jinorgbio.2026.113258_bb0020","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1021\/bi00324a025","volume":"24","author":"Marie","year":"1985","journal-title":"Biochemistry"},{"key":"10.1016\/j.jinorgbio.2026.113258_bb0025","doi-asserted-by":"crossref","first-page":"3436","DOI":"10.1021\/acs.chemrev.5b00597","volume":"116","author":"Johnstone","year":"2016","journal-title":"Chem. Rev."},{"key":"10.1016\/j.jinorgbio.2026.113258_bb0030","doi-asserted-by":"crossref","first-page":"12309","DOI":"10.1021\/ja9625079","volume":"118","author":"Takahara","year":"1996","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.jinorgbio.2026.113258_bb0035","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.ica.2017.06.047","volume":"472","author":"Lippert","year":"2018","journal-title":"Inorg. Chim. Acta"},{"key":"10.1016\/j.jinorgbio.2026.113258_bb0040","volume":"2","author":"Scattolin","year":"2021","journal-title":"Cell Rep. Phys. Sci."},{"key":"10.1016\/j.jinorgbio.2026.113258_bb0045","doi-asserted-by":"crossref","first-page":"1770","DOI":"10.1016\/j.bmc.2017.01.033","volume":"25","author":"Kacar","year":"2017","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.jinorgbio.2026.113258_bb0050","doi-asserted-by":"crossref","first-page":"5580","DOI":"10.1016\/j.bmc.2015.07.026","volume":"23","author":"Karakas","year":"2015","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.jinorgbio.2026.113258_bb0055","doi-asserted-by":"crossref","first-page":"4957","DOI":"10.1016\/j.ejmech.2011.07.055","volume":"46","author":"Ulukaya","year":"2011","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.jinorgbio.2026.113258_bb0060","doi-asserted-by":"crossref","DOI":"10.1093\/bulcsj\/uoad017","volume":"97","author":"Nakai","year":"2024","journal-title":"Bull. Chem. Soc. Jpn."},{"key":"10.1016\/j.jinorgbio.2026.113258_bb0065","doi-asserted-by":"crossref","first-page":"2676","DOI":"10.1016\/j.ccr.2011.06.012","volume":"255","author":"McKinley","year":"2011","journal-title":"Coord. Chem. Rev."},{"key":"10.1016\/j.jinorgbio.2026.113258_bb0070","doi-asserted-by":"crossref","first-page":"4960","DOI":"10.1021\/ja00168a052","volume":"112","author":"Friedman","year":"2002","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.jinorgbio.2026.113258_bb0075","doi-asserted-by":"crossref","first-page":"13261","DOI":"10.1039\/C6DT01624C","volume":"45","author":"Li","year":"2016","journal-title":"Dalton Trans."},{"key":"10.1016\/j.jinorgbio.2026.113258_bb0080","doi-asserted-by":"crossref","first-page":"2925","DOI":"10.1021\/jacs.8b09999","volume":"141","author":"Jarman","year":"2019","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.jinorgbio.2026.113258_bb0085","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1021\/ic00105a004","volume":"34","author":"Holmlin","year":"2002","journal-title":"Inorg. Chem."},{"key":"10.1016\/j.jinorgbio.2026.113258_bb0090","doi-asserted-by":"crossref","first-page":"5236","DOI":"10.1021\/ja953941y","volume":"118","author":"Holmlin","year":"1996","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.jinorgbio.2026.113258_bb0095","doi-asserted-by":"crossref","first-page":"14947","DOI":"10.1021\/acs.inorgchem.2c01231","volume":"61","author":"Stitch","year":"2022","journal-title":"Inorg. Chem."},{"key":"10.1016\/j.jinorgbio.2026.113258_bb0100","doi-asserted-by":"crossref","DOI":"10.1016\/j.jinorgbio.2024.112600","volume":"257","author":"de Lavor","year":"2024","journal-title":"J. Inorg. Biochem."},{"key":"10.1016\/j.jinorgbio.2026.113258_bb0105","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1021\/acsabm.2c00556","volume":"6","author":"Das","year":"2023","journal-title":"ACS Appl. Bio Mater."},{"key":"10.1016\/j.jinorgbio.2026.113258_bb0110","doi-asserted-by":"crossref","first-page":"3686","DOI":"10.1002\/anie.200604837","volume":"46","author":"Foxon","year":"2007","journal-title":"Angew. Chem. Int. Ed. Eng."},{"key":"10.1016\/j.jinorgbio.2026.113258_bb0115","doi-asserted-by":"crossref","DOI":"10.3390\/inorganics11090353","volume":"11","author":"James","year":"2023","journal-title":"Inorganics"},{"key":"10.1016\/j.jinorgbio.2026.113258_bb0120","doi-asserted-by":"crossref","first-page":"4607","DOI":"10.1002\/chem.201705362","volume":"24","author":"Pracharova","year":"2018","journal-title":"Chemistry"},{"key":"10.1016\/j.jinorgbio.2026.113258_bb0125","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.bpc.2005.12.011","volume":"121","author":"Mudasir","year":"2006","journal-title":"Biophys. Chem."},{"key":"10.1016\/j.jinorgbio.2026.113258_bb0130","doi-asserted-by":"crossref","first-page":"2595","DOI":"10.1039\/a903417j","author":"Fees","year":"1999","journal-title":"J. Chem. Soc. Dalton Trans."},{"key":"10.1016\/j.jinorgbio.2026.113258_bb0135","doi-asserted-by":"crossref","first-page":"6649","DOI":"10.1021\/acs.inorgchem.1c00444","volume":"60","author":"Sarkar","year":"2021","journal-title":"Inorg. Chem."},{"key":"10.1016\/j.jinorgbio.2026.113258_bb0140","doi-asserted-by":"crossref","first-page":"4267","DOI":"10.1021\/ic9508684","volume":"35","author":"Arounaguiri","year":"1996","journal-title":"Inorg. Chem."},{"key":"10.1016\/j.jinorgbio.2026.113258_bb0145","doi-asserted-by":"crossref","first-page":"3350","DOI":"10.1002\/(SICI)1521-3765(19991105)5:11<3350::AID-CHEM3350>3.0.CO;2-J","volume":"5","author":"Che","year":"1999","journal-title":"Chem. Eur. J."},{"key":"10.1016\/j.jinorgbio.2026.113258_bb0150","doi-asserted-by":"crossref","first-page":"1917","DOI":"10.1002\/ejic.200200617","volume":"2003","author":"Klein","year":"2003","journal-title":"Eur. J. Inorg. Chem."},{"key":"10.1016\/j.jinorgbio.2026.113258_bb0155","doi-asserted-by":"crossref","first-page":"2416","DOI":"10.1021\/ic035016f","volume":"43","author":"Cusumano","year":"2004","journal-title":"Inorg. Chem."},{"key":"10.1016\/j.jinorgbio.2026.113258_bb0160","doi-asserted-by":"crossref","first-page":"7970","DOI":"10.1021\/ic051124l","volume":"44","author":"Lu","year":"2005","journal-title":"Inorg. Chem."},{"key":"10.1016\/j.jinorgbio.2026.113258_bb0165","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1021\/ic050880o","volume":"45","author":"Cusumano","year":"2006","journal-title":"Inorg. Chem."},{"key":"10.1016\/j.jinorgbio.2026.113258_bb0170","doi-asserted-by":"crossref","first-page":"1427","DOI":"10.1002\/cmdc.200800097","volume":"3","author":"Roy","year":"2008","journal-title":"ChemMedChem"},{"key":"10.1016\/j.jinorgbio.2026.113258_bb0175","doi-asserted-by":"crossref","first-page":"1835","DOI":"10.1021\/ja806045x","volume":"131","author":"Ma","year":"2009","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.jinorgbio.2026.113258_bb0180","doi-asserted-by":"crossref","first-page":"1720","DOI":"10.1039\/c2cc37759d","volume":"49","author":"Ben-David","year":"2013","journal-title":"Chem. Commun. (Camb.)"},{"key":"10.1016\/j.jinorgbio.2026.113258_bb0185","doi-asserted-by":"crossref","DOI":"10.1002\/aoc.3868","volume":"31","author":"Rajesh","year":"2017","journal-title":"Appl. Organomet. Chem."},{"key":"10.1016\/j.jinorgbio.2026.113258_bb0190","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1007\/s10637-017-0559-4","volume":"36","author":"Kaplan","year":"2018","journal-title":"Investig. New Drugs"},{"key":"10.1016\/j.jinorgbio.2026.113258_bb0195","doi-asserted-by":"crossref","first-page":"7031","DOI":"10.1021\/acs.inorgchem.0c03553","volume":"60","author":"Mala","year":"2021","journal-title":"Inorg. Chem."},{"key":"10.1016\/j.jinorgbio.2026.113258_bb0200","doi-asserted-by":"crossref","first-page":"2178","DOI":"10.1021\/acs.inorgchem.0c02648","volume":"60","author":"Zamora","year":"2021","journal-title":"Inorg. Chem."},{"key":"10.1016\/j.jinorgbio.2026.113258_bb0205","doi-asserted-by":"crossref","first-page":"6014","DOI":"10.1021\/om060624z","volume":"25","author":"Bergman","year":"2006","journal-title":"Organometallics"},{"key":"10.1016\/j.jinorgbio.2026.113258_bb0210","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1134\/S1070363206020253","volume":"76","author":"Farus","year":"2006","journal-title":"Russ. J. Gen. Chem."},{"key":"10.1016\/j.jinorgbio.2026.113258_bb0215","doi-asserted-by":"crossref","first-page":"1355","DOI":"10.1590\/S0103-50532008000700018","volume":"19","author":"Navarro","year":"2008","journal-title":"J. Braz. Chem. Soc."},{"key":"10.1016\/j.jinorgbio.2026.113258_bb0220","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1021\/om700524v","volume":"27","author":"Villagra","year":"2008","journal-title":"Organometallics"},{"key":"10.1016\/j.jinorgbio.2026.113258_bb0225","doi-asserted-by":"crossref","first-page":"4331","DOI":"10.1039\/b926233d","volume":"39","author":"Butsch","year":"2010","journal-title":"Dalton Trans."},{"key":"10.1016\/j.jinorgbio.2026.113258_bb0230","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1039\/b608255f","volume":"6","author":"Puntoriero","year":"2007","journal-title":"Photochem. Photobiol. Sci."},{"key":"10.1016\/j.jinorgbio.2026.113258_bb0235","doi-asserted-by":"crossref","DOI":"10.1155\/2007\/98732","volume":"2007","author":"Riera","year":"2007","journal-title":"Bioinorg. Chem. Appl."},{"key":"10.1016\/j.jinorgbio.2026.113258_bb0240","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1039\/c2mt20022h","volume":"4","author":"Uemura","year":"2012","journal-title":"Metallomics"},{"key":"10.1016\/j.jinorgbio.2026.113258_bb0245","doi-asserted-by":"crossref","first-page":"8587","DOI":"10.1039\/C6DT00294C","volume":"45","author":"Musumeci","year":"2016","journal-title":"Dalton Trans."},{"key":"10.1016\/j.jinorgbio.2026.113258_bb0250","doi-asserted-by":"crossref","first-page":"10025","DOI":"10.1021\/ic8012359","volume":"47","author":"Ruiz","year":"2008","journal-title":"Inorg. Chem."},{"key":"10.1016\/j.jinorgbio.2026.113258_bb0255","doi-asserted-by":"crossref","first-page":"11709","DOI":"10.1021\/acs.inorgchem.5b01647","volume":"54","author":"Villarreal","year":"2015","journal-title":"Inorg. Chem."},{"key":"10.1016\/j.jinorgbio.2026.113258_bb0260","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1039\/c2mt20026k","volume":"4","author":"Uemura","year":"2012","journal-title":"Metallomics"},{"key":"10.1016\/j.jinorgbio.2026.113258_bb0265","doi-asserted-by":"crossref","first-page":"6124","DOI":"10.1021\/acs.inorgchem.8b00713","volume":"57","author":"Perez-Arnaiz","year":"2018","journal-title":"Inorg. Chem."},{"key":"10.1016\/j.jinorgbio.2026.113258_bb0270","doi-asserted-by":"crossref","first-page":"1956","DOI":"10.1021\/bm049668m","volume":"5","author":"Tian","year":"2004","journal-title":"Biomacromolecules"},{"key":"10.1016\/j.jinorgbio.2026.113258_bb0275","doi-asserted-by":"crossref","first-page":"5625","DOI":"10.1021\/jp100903x","volume":"114","author":"Zhao","year":"2010","journal-title":"J. Phys. Chem. B"},{"key":"10.1016\/j.jinorgbio.2026.113258_bb0280","doi-asserted-by":"crossref","first-page":"3133","DOI":"10.1021\/ic971194v","volume":"37","author":"Collins","year":"1998","journal-title":"Inorg. Chem."},{"key":"10.1016\/j.jinorgbio.2026.113258_bb0285","doi-asserted-by":"crossref","first-page":"1280","DOI":"10.1021\/ic50112a025","volume":"11","author":"Price","year":"1972","journal-title":"Inorg. Chem."},{"key":"10.1016\/j.jinorgbio.2026.113258_bb0290","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/S0022-2836(65)80106-1","volume":"13","author":"Felsenfeld","year":"1965","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.jinorgbio.2026.113258_bb0295","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1107\/S2053273314026370","volume":"71","author":"Sheldrick","year":"2015","journal-title":"Acta Crystallogr. A Found Adv."},{"key":"10.1016\/j.jinorgbio.2026.113258_bb0300","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1107\/S2053229614024218","volume":"71","author":"Sheldrick","year":"2015","journal-title":"Acta Crystallogr. C Struct. Chem."},{"key":"10.1016\/j.jinorgbio.2026.113258_bb0305","series-title":"Crystal Structure Version 4.3","year":"2018"}],"container-title":["Journal of Inorganic Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0162013426000474?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0162013426000474?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T04:10:11Z","timestamp":1782187811000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0162013426000474"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5]]},"references-count":61,"alternative-id":["S0162013426000474"],"URL":"https:\/\/doi.org\/10.1016\/j.jinorgbio.2026.113258","relation":{},"ISSN":["0162-0134"],"issn-type":[{"value":"0162-0134","type":"print"}],"subject":[],"published":{"date-parts":[[2026,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Pt(II) and Pd(II) complexes bearing 1,10-phenanthroline-based ligands: Distinct binding modes to DNA and anticancer activities","name":"articletitle","label":"Article Title"},{"value":"Journal of Inorganic Biochemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jinorgbio.2026.113258","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"113258"}}