{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T02:17:19Z","timestamp":1783131439279,"version":"3.54.6"},"reference-count":69,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100009108","name":"Shandong University","doi-asserted-by":"publisher","award":["S202310446004"],"award-info":[{"award-number":["S202310446004"]}],"id":[{"id":"10.13039\/100009108","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010029","name":"Taishan Scholar Foundation of Shandong Province","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010029","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010040","name":"Taishan Scholar Project of Shandong Province","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010040","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Inorganic Biochemistry"],"published-print":{"date-parts":[[2026,9]]},"DOI":"10.1016\/j.jinorgbio.2026.113347","type":"journal-article","created":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T22:15:58Z","timestamp":1777846558000},"page":"113347","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Anticancer evaluation of ferrocene-modified half-sandwich ruthenium(II) acylhydrazone complexes against A549 cell lines"],"prefix":"10.1016","volume":"282","author":[{"given":"Yuan","family":"Gao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoshuang","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jia","family":"Wen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuxin","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongfeng","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luoyi","family":"Bu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuying","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xicheng","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiang-ai","family":"Yuan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhe","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jinorgbio.2026.113347_bb0005","doi-asserted-by":"crossref","first-page":"6167","DOI":"10.2147\/IJN.S261638","volume":"15","author":"Khaledian","year":"2020","journal-title":"Int. J. Nanomedicine"},{"key":"10.1016\/j.jinorgbio.2026.113347_bb0010","volume":"12","author":"Chen","year":"2021","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.jinorgbio.2026.113347_bb0015","volume":"14","author":"Zhang","year":"2022","journal-title":"Pharmaceutics"},{"key":"10.1016\/j.jinorgbio.2026.113347_bb0020","doi-asserted-by":"crossref","first-page":"5200","DOI":"10.7150\/thno.27806","volume":"8","author":"Zhou","year":"2018","journal-title":"Theranostics"},{"key":"10.1016\/j.jinorgbio.2026.113347_bb0025","volume":"13","author":"Wang","year":"2014","journal-title":"Mol. Cancer"},{"key":"10.1016\/j.jinorgbio.2026.113347_bb0030","doi-asserted-by":"crossref","DOI":"10.3390\/ijms21228875","volume":"21","author":"Nardini","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.jinorgbio.2026.113347_bb0035","volume":"19","author":"Hwang","year":"2018","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.jinorgbio.2026.113347_bb0040","volume":"13","author":"Shi","year":"2022","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.jinorgbio.2026.113347_bb0045","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1177\/17588359221118020","volume":"14","author":"Dai","year":"2022","journal-title":"Ther. Adv. Med. Oncol."},{"key":"10.1016\/j.jinorgbio.2026.113347_bb0050","volume":"15","author":"Huang","year":"2022","journal-title":"Pharmaceuticals"},{"key":"10.1016\/j.jinorgbio.2026.113347_bb0055","volume":"12","author":"Li","year":"2022","journal-title":"Front. Oncol."},{"issue":"22","key":"10.1016\/j.jinorgbio.2026.113347_bb0060","doi-asserted-by":"crossref","first-page":"6541","DOI":"10.1039\/D2SC01518H","volume":"13","author":"Li","year":"2026","journal-title":"Chem. Sci."},{"key":"10.1016\/j.jinorgbio.2026.113347_bb0065","doi-asserted-by":"crossref","DOI":"10.3389\/fonc.2019.00562","volume":"9","author":"Neves","year":"2019","journal-title":"Front. Oncol."},{"key":"10.1016\/j.jinorgbio.2026.113347_bb0070","doi-asserted-by":"crossref","first-page":"4976","DOI":"10.3390\/ijms23094976","volume":"23","author":"Hildebrandt","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.jinorgbio.2026.113347_bb0075","doi-asserted-by":"crossref","first-page":"00508","DOI":"10.3389\/fonc.2019.00508","volume":"9","author":"Huang","year":"2019","journal-title":"Front. Oncol."},{"key":"10.1016\/j.jinorgbio.2026.113347_bb0080","doi-asserted-by":"crossref","first-page":"2918","DOI":"10.7150\/thno.41077","volume":"10","author":"Zhang","year":"2020","journal-title":"Theranostics"},{"key":"10.1016\/j.jinorgbio.2026.113347_bb0085","doi-asserted-by":"crossref","first-page":"2870","DOI":"10.1038\/s41467-018-05305-2","volume":"9","author":"Blumenfeld","year":"2018","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jinorgbio.2026.113347_bb0090","doi-asserted-by":"crossref","first-page":"5519","DOI":"10.1128\/AAC.00040-14","volume":"58","author":"Wein","year":"2014","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.jinorgbio.2026.113347_bb0095","doi-asserted-by":"crossref","first-page":"194","DOI":"10.4143\/crt.2018.031","volume":"51","author":"Ma","year":"2019","journal-title":"Cancer Res. Treat."},{"key":"10.1016\/j.jinorgbio.2026.113347_bb0100","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.csbj.2018.11.010","volume":"17","author":"Zhao","year":"2019","journal-title":"Comput. Struct. Biotechnol. J."},{"key":"10.1016\/j.jinorgbio.2026.113347_bb0105","doi-asserted-by":"crossref","first-page":"1721","DOI":"10.1021\/om0610795","volume":"26","author":"Zhu","year":"2007","journal-title":"Organometallics"},{"key":"10.1016\/j.jinorgbio.2026.113347_bb0110","doi-asserted-by":"crossref","first-page":"4243","DOI":"10.1016\/j.jorganchem.2005.06.023","volume":"690","author":"Singh","year":"2005","journal-title":"J. Organomet. Chem."},{"key":"10.1016\/j.jinorgbio.2026.113347_bb0115","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1080\/00958972.2014.977270","volume":"68","author":"Sun","year":"2015","journal-title":"J. Coord. Chem."},{"key":"10.1016\/j.jinorgbio.2026.113347_bb0120","doi-asserted-by":"crossref","first-page":"1679","DOI":"10.1002\/ejic.201601137","volume":"2017","author":"Chan","year":"2017","journal-title":"Eur. J. Inorg. Chem."},{"key":"10.1016\/j.jinorgbio.2026.113347_bb0125","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1038\/s41401-019-0340-7","volume":"41","author":"Zheng","year":"2020","journal-title":"Acta Pharmacol. Sin."},{"key":"10.1016\/j.jinorgbio.2026.113347_bb0130","doi-asserted-by":"crossref","first-page":"6865","DOI":"10.1039\/C7SC02205K","volume":"8","author":"Li","year":"2017","journal-title":"Chem. Sci."},{"key":"10.1016\/j.jinorgbio.2026.113347_bb0135","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1039\/C9SC04710G","volume":"11","author":"Smitten","year":"2020","journal-title":"Chem. Sci."},{"key":"10.1016\/j.jinorgbio.2026.113347_bb0140","volume":"348","author":"Zhang","year":"2022","journal-title":"J. Mol. Liq."},{"key":"10.1016\/j.jinorgbio.2026.113347_bb0145","doi-asserted-by":"crossref","first-page":"13469","DOI":"10.1039\/D4DT01845A","volume":"53","author":"Prabaharan","year":"2024","journal-title":"Dalton Trans."},{"key":"10.1016\/j.jinorgbio.2026.113347_bb0150","doi-asserted-by":"crossref","DOI":"10.1016\/j.molstruc.2021.131122","volume":"1246","author":"Welsh","year":"2021","journal-title":"J. Mol. Struct."},{"key":"10.1016\/j.jinorgbio.2026.113347_bb0155","doi-asserted-by":"crossref","first-page":"12233","DOI":"10.3390\/ijms232012233","volume":"23","author":"Kova\u010devi\u0107","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.jinorgbio.2026.113347_bb0160","doi-asserted-by":"crossref","first-page":"3097","DOI":"10.3390\/ijms22063097","volume":"22","author":"Zheng","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.jinorgbio.2026.113347_bb0165","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.ejmech.2014.06.052","volume":"84","author":"Paitandi","year":"2014","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.jinorgbio.2026.113347_bb0170","volume":"61","author":"Wang","year":"2022","journal-title":"Angew. Chem. Int. Ed."},{"key":"10.1016\/j.jinorgbio.2026.113347_bb0175","doi-asserted-by":"crossref","first-page":"3737","DOI":"10.1002\/chem.202004024","volume":"27","author":"Allison","year":"2021","journal-title":"Chemistry"},{"key":"10.1016\/j.jinorgbio.2026.113347_bb0180","volume":"10","author":"Wang","year":"2022","journal-title":"Front. Chem."},{"key":"10.1016\/j.jinorgbio.2026.113347_bb0185","doi-asserted-by":"crossref","first-page":"5466","DOI":"10.1039\/D0SC00897D","volume":"11","author":"Zhang","year":"2020","journal-title":"Chem. Sci."},{"issue":"1","key":"10.1016\/j.jinorgbio.2026.113347_bb0190","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1007\/s00214-022-02950-1","volume":"142","author":"Taharchaouche","year":"2023","journal-title":"Theor. Chem. Accounts"},{"key":"10.1016\/j.jinorgbio.2026.113347_bb0195","volume":"6","author":"Jagadesh Babu","year":"2023","journal-title":"Chemistry"},{"key":"10.1016\/j.jinorgbio.2026.113347_bb0200","volume":"23","author":"Lima","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.jinorgbio.2026.113347_bb0205","doi-asserted-by":"crossref","DOI":"10.1016\/j.jinorgbio.2024.112586","volume":"257","author":"Ji","year":"2024","journal-title":"J. Inorg. Biochem."},{"key":"10.1016\/j.jinorgbio.2026.113347_bb0210","doi-asserted-by":"crossref","first-page":"1500","DOI":"10.1002\/asia.201800103","volume":"13","author":"He","year":"2018","journal-title":"Chem. Asian J."},{"key":"10.1016\/j.jinorgbio.2026.113347_bb0215","doi-asserted-by":"crossref","first-page":"15888","DOI":"10.1039\/D1DT02959B","volume":"50","author":"Wang","year":"2021","journal-title":"Dalton Trans."},{"key":"10.1016\/j.jinorgbio.2026.113347_bb0220","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1021\/jm970530e","volume":"41","author":"Kansy","year":"1998","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.jinorgbio.2026.113347_bb0225","doi-asserted-by":"crossref","first-page":"2511","DOI":"10.1021\/cr9804238","volume":"99","author":"Clarke","year":"1999","journal-title":"Chem. Rev."},{"key":"10.1016\/j.jinorgbio.2026.113347_bb0230","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/j.jinorgbio.2015.07.016","volume":"153","author":"Colina-Vegas","year":"2015","journal-title":"J. Inorg. Biochem."},{"key":"10.1016\/j.jinorgbio.2026.113347_bb0235","doi-asserted-by":"crossref","first-page":"14081","DOI":"10.1039\/c3dt51275d","volume":"42","author":"Tripathy","year":"2013","journal-title":"Dalton Trans."},{"key":"10.1016\/j.jinorgbio.2026.113347_bb0240","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.jorganchem.2016.08.030","volume":"823","author":"R\u00fcther","year":"2016","journal-title":"J. Organomet. Chem."},{"key":"10.1016\/j.jinorgbio.2026.113347_bb0245","doi-asserted-by":"crossref","first-page":"13150","DOI":"10.1021\/acs.inorgchem.8b01270","volume":"57","author":"Lenis-Rojas","year":"2018","journal-title":"Inorg. Chem."},{"key":"10.1016\/j.jinorgbio.2026.113347_bb0250","doi-asserted-by":"crossref","first-page":"8832","DOI":"10.1038\/ncomms9832","volume":"6","author":"Mi","year":"2015","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jinorgbio.2026.113347_bb0255","doi-asserted-by":"crossref","first-page":"1225","DOI":"10.1039\/C7MD00074J","volume":"8","author":"Yang","year":"2017","journal-title":"MedChemComm"},{"key":"10.1016\/j.jinorgbio.2026.113347_bb0260","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1038\/nrm2745","volume":"10","author":"Saftig","year":"2009","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.jinorgbio.2026.113347_bb0265","volume":"52","author":"Sheng","year":"2019","journal-title":"Cell Prolif."},{"key":"10.1016\/j.jinorgbio.2026.113347_bb0270","doi-asserted-by":"crossref","first-page":"3823","DOI":"10.1039\/C4SC03635B","volume":"6","author":"Tsai","year":"2015","journal-title":"Chem. Sci."},{"key":"10.1016\/j.jinorgbio.2026.113347_bb0275","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1186\/s40580-020-00224-9","volume":"7","author":"Cao","year":"2020","journal-title":"Nano Convergen."},{"key":"10.1016\/j.jinorgbio.2026.113347_bb0280","doi-asserted-by":"crossref","first-page":"3856","DOI":"10.1158\/0008-5472.CAN-08-2940","volume":"69","author":"Ren","year":"2009","journal-title":"Cancer Res."},{"key":"10.1016\/j.jinorgbio.2026.113347_bb0285","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1631\/jzus.B1800211","volume":"20","author":"Ren","year":"2019","journal-title":"J. Zhejiang Univ.-Sci. B"},{"key":"10.1016\/j.jinorgbio.2026.113347_bb0290","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/s13287-019-1508-2","volume":"11","author":"Liu","year":"2020","journal-title":"Stem Cell Res. Ther."},{"key":"10.1016\/j.jinorgbio.2026.113347_bb0295","volume":"12","author":"Zhu","year":"2021","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.jinorgbio.2026.113347_bb0300","doi-asserted-by":"crossref","first-page":"2913","DOI":"10.1021\/acs.nanolett.7b00132","volume":"17","author":"Shen","year":"2017","journal-title":"Nano Lett."},{"key":"10.1016\/j.jinorgbio.2026.113347_bb0305","doi-asserted-by":"crossref","first-page":"5023","DOI":"10.2147\/IJN.S139207","volume":"12","author":"Zhu","year":"2017","journal-title":"Int. J. Nanomedicine"},{"key":"10.1016\/j.jinorgbio.2026.113347_bb0310","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1182\/blood-2008-04-151639","volume":"114","author":"Zhang","year":"2009","journal-title":"Blood"},{"key":"10.1016\/j.jinorgbio.2026.113347_bb0315","first-page":"C817","volume":"287","author":"Brookes","year":"2004","journal-title":"Am. J. Phys. Cell Phys."},{"key":"10.1016\/j.jinorgbio.2026.113347_bb0320","doi-asserted-by":"crossref","first-page":"3897","DOI":"10.1002\/anie.201108175","volume":"51","author":"Betanzos-Lara","year":"2012","journal-title":"Angew. Chem. Int. Ed."},{"key":"10.1016\/j.jinorgbio.2026.113347_bb0325","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.1038\/s41557-019-0328-4","volume":"11","author":"Huang","year":"2019","journal-title":"Nat. Chem."},{"key":"10.1016\/j.jinorgbio.2026.113347_bb0330","doi-asserted-by":"crossref","first-page":"4288","DOI":"10.1002\/ange.201300747","volume":"125","author":"Liu","year":"2013","journal-title":"Angew. Chem."},{"key":"10.1016\/j.jinorgbio.2026.113347_bb0335","doi-asserted-by":"crossref","first-page":"27934","DOI":"10.1021\/acsami.1c06381","volume":"13","author":"Xie","year":"2021","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.jinorgbio.2026.113347_bb0340","first-page":"359","volume":"5","author":"Hidayat","year":"2021","journal-title":"Bioscientia Med."},{"key":"10.1016\/j.jinorgbio.2026.113347_bb0345","volume":"39","author":"Al-Farraj","year":"2024","journal-title":"Appl. Organomet. Chem."}],"container-title":["Journal of Inorganic Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0162013426001364?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0162013426001364?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T01:22:42Z","timestamp":1783128162000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0162013426001364"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9]]},"references-count":69,"alternative-id":["S0162013426001364"],"URL":"https:\/\/doi.org\/10.1016\/j.jinorgbio.2026.113347","relation":{},"ISSN":["0162-0134"],"issn-type":[{"value":"0162-0134","type":"print"}],"subject":[],"published":{"date-parts":[[2026,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Anticancer evaluation of ferrocene-modified half-sandwich ruthenium(II) acylhydrazone complexes against A549 cell lines","name":"articletitle","label":"Article Title"},{"value":"Journal of Inorganic Biochemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jinorgbio.2026.113347","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"113347"}}