{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T05:37:40Z","timestamp":1790746660315,"version":"4.1.0"},"reference-count":42,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T00:00:00Z","timestamp":1780704000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["RF1AG083937"],"award-info":[{"award-number":["RF1AG083937"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100005471","name":"Beckman Institute for Advanced Science and Technology, University of Illinois, Urbana-Champaign","doi-asserted-by":"publisher","award":["9.4 T MRI seed grant"],"award-info":[{"award-number":["9.4 T MRI seed grant"]}],"id":[{"id":"10.13039\/100005471","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014705","name":"Society for Caribbean Studies","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100014705","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Inorganic Biochemistry"],"published-print":{"date-parts":[[2026,10]]},"DOI":"10.1016\/j.jinorgbio.2026.113377","type":"journal-article","created":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T15:26:29Z","timestamp":1780759589000},"page":"113377","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Mn(II) MRI contrast agents supported by unsymmetric pyridinophane-picolinate ligands"],"prefix":"10.1016","volume":"283","author":[{"given":"Tarek","family":"El Sayed","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shreyan","family":"Majumdar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bradley P.","family":"Sutton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liviu M.","family":"Mirica","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jinorgbio.2026.113377_bb0005","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1136\/bmj.324.7328.35","volume":"324","author":"Berger","year":"2002","journal-title":"BMJ"},{"key":"10.1016\/j.jinorgbio.2026.113377_bb0010","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/cmmi.265","volume":"4","author":"Geraldes","year":"2009","journal-title":"Contrast Media Mol. Imaging"},{"key":"10.1016\/j.jinorgbio.2026.113377_bb0015","doi-asserted-by":"crossref","first-page":"4485","DOI":"10.1016\/j.msec.2013.07.012","volume":"33","author":"Shokrollahi","year":"2013","journal-title":"Mater. Sci. Eng. C"},{"key":"10.1016\/j.jinorgbio.2026.113377_bb0020","doi-asserted-by":"crossref","first-page":"10045","DOI":"10.1021\/jacs.2c13672","volume":"145","author":"Tang","year":"2023","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.jinorgbio.2026.113377_bb0025","doi-asserted-by":"crossref","first-page":"3152","DOI":"10.1021\/ja017168k","volume":"124","author":"Caravan","year":"2002","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.jinorgbio.2026.113377_bb0030","doi-asserted-by":"crossref","DOI":"10.1038\/s41467-019-09342-3","volume":"10","author":"Clough","year":"2019","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jinorgbio.2026.113377_bb0035","volume":"11","author":"Guo","year":"2018","journal-title":"Front. Mol. Neurosci."},{"key":"10.1016\/j.jinorgbio.2026.113377_bb0040","doi-asserted-by":"crossref","DOI":"10.1016\/j.jinorgbio.2022.112018","volume":"237","author":"Daksh","year":"2022","journal-title":"J. Inorg. Biochem."},{"key":"10.1016\/j.jinorgbio.2026.113377_bb0045","doi-asserted-by":"crossref","first-page":"1579","DOI":"10.1007\/s00330-017-5065-8","volume":"28","author":"Dekkers","year":"2018","journal-title":"Eur. Radiol."},{"key":"10.1016\/j.jinorgbio.2026.113377_bb0050","doi-asserted-by":"crossref","first-page":"1104","DOI":"10.1093\/ndt\/gfk062","volume":"21","author":"Grobner","year":"2006","journal-title":"Nephrol. Dial. Transplant."},{"key":"10.1016\/j.jinorgbio.2026.113377_bb0055","first-page":"137","volume":"56","year":"2007","journal-title":"MMWR Morb. Mortal. Wkly. Rep."},{"key":"10.1016\/j.jinorgbio.2026.113377_bb0060","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1007\/s00247-007-0633-8","volume":"38","author":"Mendichovszky","year":"2008","journal-title":"Pediatr. Radiol."},{"key":"10.1016\/j.jinorgbio.2026.113377_bb0065","doi-asserted-by":"crossref","first-page":"1461","DOI":"10.4155\/fmc-2018-0608","volume":"11","author":"Botta","year":"2019","journal-title":"Future Med. Chem."},{"key":"10.1016\/j.jinorgbio.2026.113377_bb0070","doi-asserted-by":"crossref","first-page":"8431","DOI":"10.1016\/j.tet.2011.07.076","volume":"67","author":"Pan","year":"2011","journal-title":"Tetrahedron"},{"key":"10.1016\/j.jinorgbio.2026.113377_bb0075","doi-asserted-by":"crossref","first-page":"15548","DOI":"10.1021\/jacs.5b10748","volume":"137","author":"Gale","year":"2015","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.jinorgbio.2026.113377_bb0080","doi-asserted-by":"crossref","first-page":"3224","DOI":"10.1021\/ic9020756","volume":"49","author":"Draho\u0161","year":"2010","journal-title":"Inorg. Chem."},{"key":"10.1016\/j.jinorgbio.2026.113377_bb0085","doi-asserted-by":"crossref","first-page":"1975","DOI":"10.1002\/ejic.201101336","volume":"2012","author":"Draho\u0161","year":"2012","journal-title":"Eur. J. Inorg. Chem."},{"key":"10.1016\/j.jinorgbio.2026.113377_bb0090","doi-asserted-by":"crossref","first-page":"22212","DOI":"10.1021\/jacs.2c10108","volume":"144","author":"Ndiaye","year":"2022","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.jinorgbio.2026.113377_bb0095","doi-asserted-by":"crossref","first-page":"1134","DOI":"10.1021\/acs.inorgchem.0c03276","volume":"60","author":"Garda","year":"2021","journal-title":"Inorg. Chem."},{"key":"10.1016\/j.jinorgbio.2026.113377_bb0100","doi-asserted-by":"crossref","first-page":"1662","DOI":"10.1021\/jacs.9b09407","volume":"142","author":"Bot\u00e1r","year":"2020","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.jinorgbio.2026.113377_bb0105","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1002\/ejic.201501415","volume":"2016","author":"Forg\u00e1cs","year":"2016","journal-title":"Eur. J. Inorg. Chem."},{"key":"10.1016\/j.jinorgbio.2026.113377_bb0110","doi-asserted-by":"crossref","first-page":"3268","DOI":"10.1021\/ic302785m","volume":"52","author":"Rolla","year":"2013","journal-title":"Inorg. Chem."},{"key":"10.1016\/j.jinorgbio.2026.113377_bb0115","doi-asserted-by":"crossref","first-page":"15842","DOI":"10.1021\/acs.inorgchem.3c01234","volume":"62","author":"Freire","year":"2023","journal-title":"Inorg. Chem."},{"key":"10.1016\/j.jinorgbio.2026.113377_bb0120","doi-asserted-by":"crossref","first-page":"8261","DOI":"10.1021\/acs.jmedchem.4c00344","volume":"67","author":"To\u00e0n","year":"2024","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.jinorgbio.2026.113377_bb0125","doi-asserted-by":"crossref","first-page":"10893","DOI":"10.1021\/ic301369z","volume":"51","author":"Roca-Sabio","year":"2012","journal-title":"Inorg. Chem."},{"key":"10.1016\/j.jinorgbio.2026.113377_bb0130","unstructured":"See Supporting Information."},{"key":"10.1016\/j.jinorgbio.2026.113377_bb0135","doi-asserted-by":"crossref","DOI":"10.1016\/j.poly.2020.114961","volume":"195","author":"Konieczna","year":"2021","journal-title":"Polyhedron"},{"key":"10.1016\/j.jinorgbio.2026.113377_bb0140","doi-asserted-by":"crossref","first-page":"9923","DOI":"10.1039\/C7OB02508D","volume":"15","author":"Wessel","year":"2017","journal-title":"Org. Biomol. Chem."},{"key":"10.1016\/j.jinorgbio.2026.113377_bb0145","doi-asserted-by":"crossref","first-page":"14173","DOI":"10.1021\/acs.inorgchem.2c02364","volume":"61","author":"Uzal-Varela","year":"2022","journal-title":"Inorg. Chem."},{"key":"10.1016\/j.jinorgbio.2026.113377_bb0150","doi-asserted-by":"crossref","first-page":"3192","DOI":"10.1039\/jr9530003192","author":"Irving","year":"1953","journal-title":"J. Chem. Soc."},{"key":"10.1016\/j.jinorgbio.2026.113377_bb0155","unstructured":"M. Andreas, M. Wulff, WO2011073371A1 (2011)."},{"key":"10.1016\/j.jinorgbio.2026.113377_bb0160","doi-asserted-by":"crossref","first-page":"7360","DOI":"10.1021\/ja9906960","volume":"121","author":"Bock","year":"1999","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.jinorgbio.2026.113377_bb0165","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1039\/dt9770000588","author":"May","year":"1977","journal-title":"J. Chem. Soc. Dalton Trans."},{"key":"10.1016\/j.jinorgbio.2026.113377_bb0170","doi-asserted-by":"crossref","first-page":"12164","DOI":"10.1002\/chem.201800750","volume":"24","author":"Yates","year":"2018","journal-title":"Chem. A Eur. J."},{"key":"10.1016\/j.jinorgbio.2026.113377_bb0175","doi-asserted-by":"crossref","DOI":"10.3389\/fchem.2018.00232","volume":"6","author":"Garda","year":"2018","journal-title":"Front. Chem."},{"key":"10.1016\/j.jinorgbio.2026.113377_bb0180","doi-asserted-by":"crossref","first-page":"14178","DOI":"10.1021\/jacs.1c04963","volume":"143","author":"Palagi","year":"2021","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.jinorgbio.2026.113377_bb0185","doi-asserted-by":"crossref","first-page":"2603","DOI":"10.1021\/acs.inorgchem.1c03660","volume":"61","author":"Sokolow","year":"2022","journal-title":"Inorg. Chem."},{"key":"10.1016\/j.jinorgbio.2026.113377_bb0190","doi-asserted-by":"crossref","first-page":"3701","DOI":"10.1063\/1.450939","volume":"85","author":"Gotsis","year":"1986","journal-title":"J. Chem. Phys."},{"key":"10.1016\/j.jinorgbio.2026.113377_bb0195","doi-asserted-by":"crossref","first-page":"2390","DOI":"10.1021\/acs.inorgchem.0c03277","volume":"60","author":"Nizou","year":"2021","journal-title":"Inorg. Chem."},{"key":"10.1016\/j.jinorgbio.2026.113377_bb0200","doi-asserted-by":"crossref","first-page":"18600","DOI":"10.1021\/ja4094132","volume":"135","author":"Gale","year":"2013","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.jinorgbio.2026.113377_bb0205","doi-asserted-by":"crossref","first-page":"11242","DOI":"10.1021\/acs.jmedchem.4c00812","volume":"67","author":"Harriswangler","year":"2024","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.jinorgbio.2026.113377_bb0210","volume":"128","author":"Omweri","year":"2024","journal-title":"Nucl. Med. Biol."}],"container-title":["Journal of Inorganic Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0162013426001662?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0162013426001662?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T21:35:07Z","timestamp":1785879307000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0162013426001662"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":42,"alternative-id":["S0162013426001662"],"URL":"https:\/\/doi.org\/10.1016\/j.jinorgbio.2026.113377","relation":{"has-preprint":[{"id-type":"doi","id":"10.26434\/chemrxiv.15003384\/v1","asserted-by":"object"}]},"ISSN":["0162-0134"],"issn-type":[{"value":"0162-0134","type":"print"}],"subject":[],"published":{"date-parts":[[2026,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Mn(II) MRI contrast agents supported by unsymmetric pyridinophane-picolinate ligands","name":"articletitle","label":"Article Title"},{"value":"Journal of Inorganic Biochemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jinorgbio.2026.113377","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"113377"}}