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Dis."},{"key":"10.1016\/j.jinsphys.2021.104268_b0325","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1046\/j.1461-0248.2002.00380.x","article-title":"Dissecting adaptive clinal variation: markers, inversions and size\/stress associations in Drosophila melanogaster from a central field population","volume":"5","author":"Weeks","year":"2002","journal-title":"Ecol. Lett."},{"key":"10.1016\/j.jinsphys.2021.104268_b0330","doi-asserted-by":"crossref","unstructured":"Wigglesworth, V.B., 1972. The Circulatory System and Associated Tissues, in: The Principles of Insect Physiology. Springer Netherlands, pp. 411\u2013475. https:\/\/doi.org\/10.1007\/978-94-009-5973-6_10.","DOI":"10.1007\/978-94-009-5973-6_10"},{"key":"10.1016\/j.jinsphys.2021.104268_b0335","doi-asserted-by":"crossref","unstructured":"W\u00f3jtowicz, I., Jab\u0142o\u0144ska, J., Zmojdzian, M., Taghli-Lamallem, O., Renaud, Y., Junion, G., Daczewska, M., Huelsmann, S., Jagla, K., Jagla, T., 2015. Drosophila small heat shock protein CryAB ensures structural integrity of developing muscles, and proper muscle and heart performance. Dev. 142, 994\u20131005. https:\/\/doi.org\/10.1242\/dev.115352.","DOI":"10.1242\/dev.115352"},{"key":"10.1016\/j.jinsphys.2021.104268_b0340","doi-asserted-by":"crossref","unstructured":"Yan, Y., Hillyer, J.F., 2020. The immune and circulatory systems are functionally integrated across insect evolution. Science Advances 6, eabb3164. https:\/\/doi.org\/10.1126\/sciadv.abb3164.","DOI":"10.1126\/sciadv.abb3164"},{"key":"10.1016\/j.jinsphys.2021.104268_b0345","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1186\/s40659-015-0054-3","article-title":"Transcriptome responses to heat and cold-stress in ladybirds (Cryptolaemus montrouzieri Mulasnt) analyzed by deep-sequencing","volume":"48","author":"Zhang","year":"2015","journal-title":"Biol. Res."},{"key":"10.1016\/j.jinsphys.2021.104268_b0350","doi-asserted-by":"crossref","first-page":"663","DOI":"10.3892\/ijmm.2020.4631","article-title":"TRAP1 attenuates H9C2 myocardial cell injury induced by extracellular acidification via the inhibition of MPTP opening","volume":"46","author":"Zhang","year":"2020","journal-title":"Int. J. Mol. Med."},{"issue":"7","key":"10.1016\/j.jinsphys.2021.104268_b0355","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1007\/s00360-016-0997-x","article-title":"Modulatory effects on Drosophila larva hearts: room temperature, acute and chronic cold stress","volume":"186","author":"Zhu","year":"2016","journal-title":"J. Comp. Physiol. B Biochem. Syst. Environ. 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