{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T03:21:03Z","timestamp":1793762463544,"version":"4.6.1"},"reference-count":63,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,10,4]],"date-time":"2023-10-04T00:00:00Z","timestamp":1696377600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100022965","name":"Colciencias","doi-asserted-by":"publisher","award":["566-1-2014"],"award-info":[{"award-number":["566-1-2014"]}],"id":[{"id":"10.13039\/100022965","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005278","name":"Universidad de Antioquia","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005278","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007637","name":"Departamento Administrativo de Ciencia, Tecnolog\u00eda e Innovaci\u00f3n","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007637","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Insect Physiology"],"published-print":{"date-parts":[[2023,11]]},"DOI":"10.1016\/j.jinsphys.2023.104570","type":"journal-article","created":{"date-parts":[[2023,10,6]],"date-time":"2023-10-06T11:48:41Z","timestamp":1696592921000},"page":"104570","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":20,"special_numbering":"C","title":["The effects of female age on blood-feeding, insemination, sperm storage, and fertility in the dengue vector mosquito Aedes aegypti (Diptera: Culicidae)"],"prefix":"10.1016","volume":"150","author":[{"given":"Luis Felipe","family":"Ram\u00edrez-S\u00e1nchez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brenda Juliana","family":"Hern\u00e1ndez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pablo Andr\u00e9s","family":"Guzm\u00e1n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catalina","family":"Alfonso-Parra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7278-0646","authenticated-orcid":false,"given":"Frank W.","family":"Avila","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jinsphys.2023.104570_b0005","doi-asserted-by":"crossref","DOI":"10.3389\/fphys.2021.691221","article-title":"Male age influences re-mating incidence and sperm use in females of the dengue vector Aedes aegypti","volume":"12","author":"Agudelo","year":"2021","journal-title":"Front. Physiol."},{"key":"10.1016\/j.jinsphys.2023.104570_b0010","doi-asserted-by":"crossref","DOI":"10.3389\/fitd.2022.816556","article-title":"Putative degradation of non-stored sperm in the female reproductive tract of the dengue vector mosquito Aedes aegypti","volume":"3","author":"Agudelo","year":"2022","journal-title":"Front. Trop. Dis."},{"key":"10.1016\/j.jinsphys.2023.104570_b0015","doi-asserted-by":"crossref","first-page":"e0004451","DOI":"10.1371\/journal.pntd.0004451","article-title":"Mating-induced transcriptome changes in the reproductive tract of female Aedes aegypti","volume":"10","author":"Alfonso-Parra","year":"2016","journal-title":"PLoS Negl. Trop. Dis."},{"key":"10.1016\/j.jinsphys.2023.104570_b0020","doi-asserted-by":"crossref","first-page":"E49","DOI":"10.3390\/pathogens7020049","article-title":"Molecular responses to the zika virus in mosquitoes","volume":"7","author":"Alfonso-Parra","year":"2018","journal-title":"Pathogens"},{"key":"10.1016\/j.jinsphys.2023.104570_b0025","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.jinsphys.2014.07.004","article-title":"Synthesis, depletion and cell-type expression of a protein from the male accessory glands of the dengue vector mosquito Aedes aegypti","volume":"70","author":"Alfonso-Parra","year":"2014","journal-title":"J. Insect Physiol."},{"key":"10.1016\/j.jinsphys.2023.104570_b0030","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1242\/dev.015156","article-title":"The Sf1-related nuclear hormone receptor Hr39 regulates Drosophila female reproductive tract development and function","volume":"135","author":"Allen","year":"2008","journal-title":"Development"},{"key":"10.1016\/j.jinsphys.2023.104570_b0035","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1038\/s41564-019-0619-y","article-title":"Successive blood meals enhance virus dissemination within mosquitoes and increase transmission potential","volume":"5","author":"Armstrong","year":"2020","journal-title":"Nat. Microbiol."},{"key":"10.1016\/j.jinsphys.2023.104570_b0040","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1146\/annurev-ento-120709-144823","article-title":"Insect seminal fluid proteins: identification and function","volume":"56","author":"Avila","year":"2011","journal-title":"Annu. Rev. Entomol."},{"key":"10.1016\/j.jinsphys.2023.104570_b0045","doi-asserted-by":"crossref","first-page":"1","DOI":"10.18637\/jss.v067.i01","article-title":"Fitting linear mixed-effects models using lme4","volume":"67","author":"Bates","year":"2015","journal-title":"J. Stat. Softw."},{"key":"10.1016\/j.jinsphys.2023.104570_b0050","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1111\/j.2517-6161.1995.tb02031.x","article-title":"Controlling the false discovery rate: a practical and powerful approach to multiple testing","volume":"57","author":"Benjamini","year":"1995","journal-title":"J. R. Stat. Soc. Ser. B"},{"key":"10.1016\/j.jinsphys.2023.104570_b0055","doi-asserted-by":"crossref","first-page":"14899","DOI":"10.1038\/s41598-020-71904-z","article-title":"Mating and blood-feeding induce transcriptome changes in the spermathecae of the yellow fever mosquito Aedes aegypti","volume":"10","author":"Camargo","year":"2020","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jinsphys.2023.104570_b0060","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1186\/s40409-018-0162-y","article-title":"Yellow fever in Africa and the Americas: a historical and epidemiological perspective","volume":"24","author":"Chippaux","year":"2018","journal-title":"J. Venom. Anim. Toxins Incl. Trop. Dis."},{"key":"10.1016\/j.jinsphys.2023.104570_b0065","series-title":"Aedes Aegypti (L.), the Yellow Fever Mosquito. Its life history, bionomics, and structure","author":"Christophers","year":"1960"},{"key":"10.1016\/j.jinsphys.2023.104570_b0070","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.jinsphys.2014.03.006","article-title":"Male Aedes aegypti mosquitoes use JH III transferred during copulation to influence previtellogenic ovary physiology and affect the reproductive output of female mosquitoes","volume":"64","author":"Clifton","year":"2014","journal-title":"J. Insect Physiol."},{"key":"10.1016\/j.jinsphys.2023.104570_b0075","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/0531-5565(75)90011-X","article-title":"The variability between individuals as a measure of senescence: a study of the number of eggs laid and the percentage of hatched eggs in the case of Drosophila melanogaster","volume":"10","author":"David","year":"1975","journal-title":"Exp. Gerontol."},{"key":"10.1016\/j.jinsphys.2023.104570_b0080","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1186\/s13071-016-1734-8","article-title":"The importance of male body size on sperm uptake and usage, and female fecundity in Aedes aegypti and Aedes albopictus","volume":"9","author":"De Jesus","year":"2016","journal-title":"Parasit. Vectors"},{"key":"10.1016\/j.jinsphys.2023.104570_b0085","doi-asserted-by":"crossref","first-page":"780","DOI":"10.4269\/ajtmh.15-0893","article-title":"Polyandry depends on postmating time interval in the dengue vector Aedes aegypti","volume":"94","author":"Degner","year":"2016","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1016\/j.jinsphys.2023.104570_b0090","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1002\/mrd.22653","article-title":"A mosquito sperm\u2019s journey from male ejaculate to egg: mechanisms, molecules, and methods for exploration","volume":"83","author":"Degner","year":"2016","journal-title":"Mol. Reprod. Dev."},{"key":"10.1016\/j.jinsphys.2023.104570_b0095","doi-asserted-by":"crossref","DOI":"10.3390\/v15030636","article-title":"Biology and behaviour of Aedes aegypti in the human environment: opportunities for vector control of arbovirus transmission","volume":"15","author":"Facchinelli","year":"2023","journal-title":"Viruses"},{"key":"10.1016\/j.jinsphys.2023.104570_b0100","first-page":"20130428","article-title":"Age-dependent female responses to a male ejaculate signal alter demographic opportunities for selection","volume":"280","author":"Fricke","year":"2013","journal-title":"Proc. Biol. Sci."},{"key":"10.1016\/j.jinsphys.2023.104570_b0105","doi-asserted-by":"crossref","first-page":"16353","DOI":"10.1073\/pnas.1410488111","article-title":"Sexual transfer of the steroid hormone 20E induces the postmating switch in Anopheles gambiae","volume":"111","author":"Gabrieli","year":"2014","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.jinsphys.2023.104570_b0110","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1016\/j.arr.2005.04.001","article-title":"Functional senescence in Drosophila melanogaster","volume":"4","author":"Grotewiel","year":"2005","journal-title":"Ageing Res. Rev."},{"key":"10.1016\/j.jinsphys.2023.104570_b0115","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1017\/S0007485322000396","article-title":"Effect of delayed mating on reproductive performance and life-history parameters of dengue vector Aedes aegypti","volume":"113","author":"Gunathilaka","year":"2023","journal-title":"Bull. Entomol. Res."},{"key":"10.1016\/j.jinsphys.2023.104570_b0120","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/S0140-6736(14)60572-9","article-title":"Dengue","volume":"385","author":"Guzman","year":"2015","journal-title":"Lancet"},{"key":"10.1016\/j.jinsphys.2023.104570_b0125","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/0022-1910(72)90126-6","article-title":"Neuro-hormonal regulation of sexual receptivity in female Aedes aegypti","volume":"18","author":"Gwadz","year":"1972","journal-title":"J. Insect Physiol."},{"key":"10.1016\/j.jinsphys.2023.104570_b0130","first-page":"586","article-title":"Sexual receptivity in female Aedes aegypti","volume":"28","author":"Gwadz","year":"1968","journal-title":"Mosq. News"},{"key":"10.1016\/j.jinsphys.2023.104570_b0135","doi-asserted-by":"crossref","first-page":"201","DOI":"10.2307\/1540069","article-title":"Female sexual behavior as the mechanism rendering Aedes aegypti refractory to insemination","volume":"140","author":"Gwadz","year":"1971","journal-title":"Biol. Bull."},{"key":"10.1016\/j.jinsphys.2023.104570_b0140","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/0016-6480(71)90206-1","article-title":"Precocious sexual receptivity induced by a juvenile hormone analog in females of the yellow fever mosquito, Aedes aegypti","volume":"16","author":"Gwadz","year":"1971","journal-title":"Gen. Comp. Endocrinol."},{"key":"10.1016\/j.jinsphys.2023.104570_b0145","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1603\/0022-2585-38.3.411","article-title":"Why do female Aedes aegypti (Diptera: Culicidae) feed preferentially and frequently on human blood?","volume":"38","author":"Harrington","year":"2001","journal-title":"J. Med. Entomol."},{"key":"10.1016\/j.jinsphys.2023.104570_b0150","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.1093\/jme\/tjy040","article-title":"Age and body size infuence sperm quantity in male Aedes albopictus (Diptera: Culicidae) mosquitoes","volume":"55","author":"Hatala","year":"2018","journal-title":"J. Med. Entomol."},{"key":"10.1016\/j.jinsphys.2023.104570_b0155","doi-asserted-by":"crossref","first-page":"1307","DOI":"10.1016\/j.jinsphys.2012.07.003","article-title":"Duration and dose-dependency of female sexual receptivity responses to seminal fluid proteins in Aedes albopictus and Ae. aegypti mosquitoes","volume":"58","author":"Helinski","year":"2012","journal-title":"J. Insect Physiol."},{"key":"10.1016\/j.jinsphys.2023.104570_b0160","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1603\/ME10071","article-title":"Male mating history and body size influence female fecundity and longevity of the dengue vector Aedes aegypti","volume":"48","author":"Helinski","year":"2011","journal-title":"J. Med. Entomol."},{"key":"10.1016\/j.jinsphys.2023.104570_b0165","series-title":"Encyclopedia of Reproduction","first-page":"137","article-title":"Insect male reproductive glands and their products","author":"Hopkins","year":"2018"},{"key":"10.1016\/j.jinsphys.2023.104570_b0170","doi-asserted-by":"crossref","first-page":"1460","DOI":"10.4269\/ajtmh.1980.29.1460","article-title":"\u201cPhysiologically old\u201d mosquitoes are not necessarily old physiologically","volume":"29","author":"Klowden","year":"1980","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1016\/j.jinsphys.2023.104570_b0175","doi-asserted-by":"crossref","first-page":"e0009815","DOI":"10.1371\/journal.pntd.0009815","article-title":"The impact of mating and sugar feeding on blood-feeding physiology and behavior in the arbovirus vector mosquito Aedes aegypti","volume":"15","author":"League","year":"2021","journal-title":"PLoS Negl. Trop. Dis."},{"key":"10.1016\/j.jinsphys.2023.104570_b0180","article-title":"emmeans: estimated marginal means, aka least-squares means","author":"Lenth","year":"2023","journal-title":"[WWW Document]"},{"key":"10.1016\/j.jinsphys.2023.104570_b0185","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1093\/beheco\/arq193","article-title":"Male Drosophila melanogaster adjust ejaculate size based on female mating status, fecundity, and age","volume":"22","author":"Manier","year":"2011","journal-title":"Behav. Ecol."},{"key":"10.1016\/j.jinsphys.2023.104570_b0190","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/0003-3472(67)90006-1","article-title":"The control of sexual receptivity in female Drosophila","volume":"15","author":"Manning","year":"1967","journal-title":"Anim. Behav."},{"key":"10.1016\/j.jinsphys.2023.104570_b0195","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1038\/nature13964","article-title":"Evolution of mosquito preference for humans linked to an odorant receptor","volume":"515","author":"McBride","year":"2014","journal-title":"Nature"},{"key":"10.1016\/j.jinsphys.2023.104570_b0200","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1086\/722481","article-title":"Evolution of a mosquito\u2019s hatching behavior to match its human-provided habitat","volume":"201","author":"Metz","year":"2023","journal-title":"Am. Nat."},{"key":"10.1016\/j.jinsphys.2023.104570_b0205","doi-asserted-by":"crossref","first-page":"74","DOI":"10.3390\/insects10030074","article-title":"Physiological and environmental factors affecting the composition of the ejaculate in mosquitoes and other insects","volume":"10","author":"Meuti","year":"2019","journal-title":"Insects"},{"key":"10.1016\/j.jinsphys.2023.104570_b0210","doi-asserted-by":"crossref","first-page":"127","DOI":"10.4161\/19336934.2014.969144","article-title":"The song of the old mother: reproductive senescence in female drosophila","volume":"8","author":"Miller","year":"2014","journal-title":"Fly (Austin)."},{"key":"10.1016\/j.jinsphys.2023.104570_b0215","doi-asserted-by":"crossref","DOI":"10.3390\/insects13010069","article-title":"Effects of mating on gene expression in female insects: unifying the field","volume":"13","author":"Nanfack-Minkeu","year":"2022","journal-title":"Insects"},{"key":"10.1016\/j.jinsphys.2023.104570_b0220","doi-asserted-by":"crossref","DOI":"10.1101\/pdb.prot107954","article-title":"Determining the insemination status of aedes mosquitoes","author":"Parsana","year":"2022","journal-title":"Cold Spring Harb. Protoc."},{"key":"10.1016\/j.jinsphys.2023.104570_b0225","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1186\/s12864-020-6543-y","article-title":"Transcriptional profiling and physiological roles of Aedes aegypti spermathecal-related genes","volume":"21","author":"Pascini","year":"2020","journal-title":"BMC Genom."},{"key":"10.1016\/j.jinsphys.2023.104570_b0230","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1038\/s41586-022-04908-6","article-title":"A male steroid controls female sexual behaviour in the malaria mosquito","volume":"608","author":"Peng","year":"2022","journal-title":"Nature"},{"key":"10.1016\/j.jinsphys.2023.104570_b0235","doi-asserted-by":"crossref","first-page":"395","DOI":"10.4269\/ajtmh.2009.80.395","article-title":"Factors associated with male mating success of the dengue vector mosquito, Aedes aegypti","volume":"80","author":"Ponlawat","year":"2009","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1016\/j.jinsphys.2023.104570_b0240","series-title":"R: A language and environment for statistical computing","author":"R Core Team","year":"2022"},{"key":"10.1016\/j.jinsphys.2023.104570_b0245","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ibmb.2014.05.001","article-title":"Metabolic analysis reveals changes in the mevalonate and juvenile hormone synthesis pathways linked to the mosquito reproductive physiology","volume":"51","author":"Rivera-Perez","year":"2014","journal-title":"Insect Biochem. Mol. Biol."},{"key":"10.1016\/j.jinsphys.2023.104570_b0250","doi-asserted-by":"crossref","first-page":"e1000272","DOI":"10.1371\/journal.pbio.1000272","article-title":"Transglutaminase-mediated semen coagulation controls sperm storage in the malaria mosquito","volume":"7","author":"Rogers","year":"2009","journal-title":"PLoS Biol."},{"key":"10.1016\/j.jinsphys.2023.104570_b0255","doi-asserted-by":"crossref","first-page":"265","DOI":"10.2307\/2421604","article-title":"A study of mosquito behavior. an experimental laboratory study of the sexual behavior of Aedes aegypti (Linnaeus)","volume":"40","author":"Roth","year":"1948","journal-title":"Am. Midl. Nat."},{"key":"10.1016\/j.jinsphys.2023.104570_b0260","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.exger.2017.12.013","article-title":"The impact of ageing on male reproductive success in Drosophila melanogaster","volume":"103","author":"Ruhmann","year":"2018","journal-title":"Exp. Gerontol."},{"key":"10.1016\/j.jinsphys.2023.104570_b0265","doi-asserted-by":"crossref","first-page":"e1001192","DOI":"10.1371\/journal.pbio.1001192","article-title":"Sperm-storage defects and live birth in drosophila females lacking spermathecal secretory cells","volume":"9","author":"Schnakenberg","year":"2011","journal-title":"PLoS Biol."},{"key":"10.1016\/j.jinsphys.2023.104570_b0270","doi-asserted-by":"crossref","first-page":"5854","DOI":"10.1073\/pnas.1401715111","article-title":"Mating activates the heme peroxidase HPX15 in the sperm storage organ to ensure fertility in Anopheles gambiae","volume":"111","author":"Shaw","year":"2014","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.jinsphys.2023.104570_b0275","doi-asserted-by":"crossref","first-page":"1471","DOI":"10.1016\/0022-1910(69)90168-1","article-title":"Failure of effective insemination of young female Aedes aegypti mosquitoes","volume":"15","author":"Spielman","year":"1969","journal-title":"J. Insect Physiol."},{"key":"10.1016\/j.jinsphys.2023.104570_b0280","doi-asserted-by":"crossref","first-page":"1","DOI":"10.7554\/eLife.00415","article-title":"Ovulation in Drosophila is controlled by secretory cells of the female reproductive tract","volume":"2","author":"Sun","year":"2013","journal-title":"Elife"},{"key":"10.1016\/j.jinsphys.2023.104570_b0285","doi-asserted-by":"crossref","DOI":"10.1098\/rsbl.2018.0262","article-title":"Sexual attractiveness and reproductive performance in ageing females of a coccoid insect","volume":"14","author":"Tabata","year":"2018","journal-title":"Biol. Lett."},{"key":"10.1016\/j.jinsphys.2023.104570_b0290","doi-asserted-by":"crossref","DOI":"10.1016\/j.jinsphys.2021.104245","article-title":"Age-related changes in the reproductive potential of the Queensland fruit fly","volume":"131","author":"Tasnin","year":"2021","journal-title":"J. Insect Physiol."},{"key":"10.1016\/j.jinsphys.2023.104570_b0295","doi-asserted-by":"crossref","first-page":"6294","DOI":"10.1128\/JVI.00370-14","article-title":"High level of vector competence of Aedes aegypti and Aedes albopictus from ten American countries as a crucial factor in the spread of Chikungunya virus","volume":"88","author":"Vega-R\u00faa","year":"2014","journal-title":"J. Virol."},{"key":"10.1016\/j.jinsphys.2023.104570_b0300","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jinsphys.2018.05.001","article-title":"Male contributions during mating increase female survival in the disease vector mosquito Aedes aegypti","volume":"108","author":"Villarreal","year":"2018","journal-title":"J. Insect Physiol."},{"key":"10.1016\/j.jinsphys.2023.104570_b0305","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.ibmb.2016.08.003","article-title":"Determination of juvenile hormone titers by means of LC-MS\/MS\/MS and a juvenile hormone-responsive Gal4\/UAS system in Aedes aegypti mosquitoes","volume":"77","author":"Zhao","year":"2016","journal-title":"Insect Biochem. Mol. Biol."},{"key":"10.1016\/j.jinsphys.2023.104570_b0310","doi-asserted-by":"crossref","DOI":"10.3390\/insects12060529","article-title":"Factors influencing the reproductive ability of male bees: current knowledge and further directions","volume":"12","author":"Zhao","year":"2021","journal-title":"Insects"},{"key":"10.1016\/j.jinsphys.2023.104570_b0315","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1111\/j.1474-9726.2008.00379.x","article-title":"Age-related changes of germline stem cell activity, niche signaling activity and egg production in Drosophila","volume":"7","author":"Zhao","year":"2008","journal-title":"Aging Cell"}],"container-title":["Journal of Insect Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022191023000963?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022191023000963?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,19]],"date-time":"2025-09-19T16:53:27Z","timestamp":1758300807000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022191023000963"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11]]},"references-count":63,"alternative-id":["S0022191023000963"],"URL":"https:\/\/doi.org\/10.1016\/j.jinsphys.2023.104570","relation":{},"ISSN":["0022-1910"],"issn-type":[{"value":"0022-1910","type":"print"}],"subject":[],"published":{"date-parts":[[2023,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The effects of female age on blood-feeding, insemination, sperm storage, and fertility in the dengue vector mosquito Aedes aegypti (Diptera: Culicidae)","name":"articletitle","label":"Article Title"},{"value":"Journal of Insect Physiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jinsphys.2023.104570","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Author(s). Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"104570"}}