{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,6]],"date-time":"2026-09-06T05:16:36Z","timestamp":1788671796850,"version":"build-2803163510"},"reference-count":25,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31972332"],"award-info":[{"award-number":["31972332"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Invertebrate Pathology"],"published-print":{"date-parts":[[2026,11]]},"DOI":"10.1016\/j.jip.2026.108709","type":"journal-article","created":{"date-parts":[[2026,7,18]],"date-time":"2026-07-18T15:15:16Z","timestamp":1784387716000},"page":"108709","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Dual regulatory roles of the zinc cluster transcription factor MrFTRP1 in development, stress tolerance, and virulence of Metarhizium robertsii"],"prefix":"10.1016","volume":"219","author":[{"given":"Chentian","family":"Jiang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Youmin","family":"Tong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lili","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/j.jip.2026.108709_bb0005","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1007\/s11103-015-0413-z","article-title":"Fungi with multifunctional lifestyles: endophytic insect pathogenic fungi","volume":"90","author":"Barelli","year":"2016","journal-title":"Plant Mol. Biol."},{"issue":"4","key":"10.1016\/j.jip.2026.108709_bb0010","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1099\/mic.0.2006\/002105-0","article-title":"A regulator of a G protein signalling (RGS) gene, cag8, from the insect-pathogenic fungus Metarhizium anisopliae is involved in conidiation, virulence and hydrophobin synthesis","volume":"153","author":"Fang","year":"2007","journal-title":"Microbiology (Reading)"},{"key":"10.1016\/j.jip.2026.108709_bb0015","doi-asserted-by":"crossref","DOI":"10.1016\/j.pestbp.2025.106856","article-title":"Regulatory roles of three Zn(II)2Cys6 cluster-coding genes in insect pathogenicity and environmental fitness of Beauveria bassiana","volume":"217","author":"Feng","year":"2026","journal-title":"Pestic. Biochem. Physiol."},{"issue":"7","key":"10.1016\/j.jip.2026.108709_bb0020","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1006516","article-title":"Tpc1 is an important Zn(II)2Cys6 transcriptional regulator required for polarized growth and virulence in the rice blast fungus","volume":"13","author":"Galhano","year":"2017","journal-title":"PLoS Pathog."},{"issue":"1","key":"10.1016\/j.jip.2026.108709_bb0025","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1001264","article-title":"Genome sequencing and comparative transcriptomics of the model entomopathogenic fungi Metarhizium anisopliae and M. acridum","volume":"7","author":"Gao","year":"2011","journal-title":"PLoS Genet."},{"issue":"1","key":"10.1016\/j.jip.2026.108709_bb0030","doi-asserted-by":"crossref","DOI":"10.1038\/s41467-017-01756-1","article-title":"Alternative transcription start site selection in Mr-OPY2 controls lifestyle transitions in the fungus Metarhizium robertsii","volume":"8","author":"Guo","year":"2017","journal-title":"Nat. Commun."},{"issue":"13","key":"10.1016\/j.jip.2026.108709_bb0035","doi-asserted-by":"crossref","first-page":"8218","DOI":"10.1074\/jbc.M114.630939","article-title":"Basic leucine zipper (bZIP) domain transcription factor MBZ1 regulates cell wall integrity, spore adherence, and virulence in Metarhizium robertsii","volume":"290","author":"Huang","year":"2015","journal-title":"J. Biol. Chem."},{"issue":"6","key":"10.1016\/j.jip.2026.108709_bb0040","doi-asserted-by":"crossref","DOI":"10.1016\/j.funbio.2025.101636","article-title":"The transcription factor MrbHLH2 significantly affects stress resistance and insect virulence in Metarhizium robertsii","volume":"129","author":"Kong","year":"2025","journal-title":"Fungal Biol."},{"key":"10.1016\/j.jip.2026.108709_bb0045","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.fgb.2013.02.008","article-title":"Insight into the transcriptional regulation of Msn2 required for conidiation, multi-stress responses and virulence of two entomopathogenic fungi","volume":"54","author":"Liu","year":"2013","journal-title":"Fungal Genet. Biol."},{"issue":"5","key":"10.1016\/j.jip.2026.108709_bb0050","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1007\/s11427-022-2238-8","article-title":"Promotion of Arabidopsis immune responses by a rhizosphere fungus via supply of pipecolic acid to plants and selective augment of phytoalexins","volume":"66","author":"Luo","year":"2023","journal-title":"Sci. China Life Sci."},{"issue":"3","key":"10.1016\/j.jip.2026.108709_bb0055","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1128\/MMBR.00015-06","article-title":"A fungal family of transcriptional regulators: the zinc cluster proteins","volume":"70","author":"MacPherson","year":"2006","journal-title":"Microbiol. Mol. Biol. Rev."},{"key":"10.1016\/j.jip.2026.108709_bb0060","doi-asserted-by":"crossref","DOI":"10.1016\/j.fgb.2019.103244","article-title":"MrSt12 implicated in the regulation of transcription factor AFTF1 by Fus3-MAPK during cuticle penetration by the entomopathogenic fungus Metarhizium robertsii","volume":"131","author":"Meng","year":"2019","journal-title":"Fungal Genet. Biol."},{"issue":"10","key":"10.1016\/j.jip.2026.108709_bb0065","doi-asserted-by":"crossref","first-page":"6229","DOI":"10.1002\/ps.8961","article-title":"Dissecting the multifaceted influence of the MrBHLH1 transcription factor on development, stress response, and virulence in Metarhizium robertsii","volume":"81","author":"Qu","year":"2025","journal-title":"Pest Manag. Sci."},{"key":"10.1016\/j.jip.2026.108709_bb0070","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0065-2164(04)54001-7","article-title":"Metarhizium spp., cosmopolitan insect-pathogenic fungi: mycological aspects","volume":"54","author":"Roberts","year":"2004","journal-title":"Adv. Appl. Microbiol."},{"key":"10.1016\/j.jip.2026.108709_bb0075","doi-asserted-by":"crossref","DOI":"10.3389\/fgene.2017.00053","article-title":"Transcription factors in Fungi: TFome dynamics, three major families, and dual-specificity TFs","volume":"8","author":"Shelest","year":"2017","journal-title":"Front. Genet."},{"key":"10.1016\/j.jip.2026.108709_bb0080","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1146\/annurev-ento-031616-035509","article-title":"Insect pathogenic fungi: genomics, molecular interactions, and genetic improvements","volume":"62","author":"Wang","year":"2017","journal-title":"Annu. Rev. Entomol."},{"issue":"10","key":"10.1016\/j.jip.2026.108709_bb0085","doi-asserted-by":"crossref","first-page":"4215","DOI":"10.1007\/s00253-017-8197-5","article-title":"DNA methyltransferases contribute to the fungal development, stress tolerance and virulence of the entomopathogenic fungus Metarhizium robertsii","volume":"101","author":"Wang","year":"2017","journal-title":"Appl. Microbiol. Biotechnol."},{"issue":"1","key":"10.1016\/j.jip.2026.108709_bb0090","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1016\/j.fmre.2024.02.003","article-title":"Accumulation of the spontaneous and random mutations is causative of fungal culture degeneration","volume":"6","author":"Wang","year":"2024","journal-title":"Fundam. Res."},{"issue":"2","key":"10.1016\/j.jip.2026.108709_bb0095","doi-asserted-by":"crossref","DOI":"10.1128\/Spectrum.00823-21","article-title":"Mr-AbaA regulates conidiation by interacting with the promoter regions of both Mr-veA and Mr-wetA in Metarhizium robertsii","volume":"9","author":"Wu","year":"2021","journal-title":"Microbiol. Spectrum"},{"key":"10.1016\/j.jip.2026.108709_bb0100","doi-asserted-by":"crossref","DOI":"10.1016\/j.jip.2026.108558","article-title":"MrBZIP, a MrWETA-interacting transcription factor, mediates oxidative and heat stress tolerance in conidia of Metarhizium robertsii","volume":"216","author":"Wu","year":"2026","journal-title":"J. Invertebr. Pathol."},{"key":"10.1016\/j.jip.2026.108709_bb0105","article-title":"The APSES gene MrStuA regulates sporulation in Metarhizium robertsii","volume":"9","author":"Yang","year":"2018","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.jip.2026.108709_bb0110","doi-asserted-by":"crossref","DOI":"10.1016\/j.jip.2024.108071","article-title":"The homeobox transcription factor MrHOX7 contributes to stress tolerance and virulence in the entomopathogenic fungus Metarhizium robertsii","volume":"203","author":"Yang","year":"2024","journal-title":"J. Invertebr. Pathol."},{"issue":"8","key":"10.1016\/j.jip.2026.108709_bb0115","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pbio.3001360","article-title":"A novel cascade allows Metarhizium robertsii to distinguish cuticle and hemocoel microenvironments during infection of insects","volume":"19","author":"Zhang","year":"2021","journal-title":"PLoS Biol."},{"issue":"10","key":"10.1016\/j.jip.2026.108709_bb0120","doi-asserted-by":"crossref","DOI":"10.3390\/jof8101110","article-title":"Roles of BrlA and AbaA in mediating asexual and insect pathogenic lifecycles of Metarhizium robertsii","volume":"8","author":"Zhang","year":"2022","journal-title":"J Fungi."},{"issue":"2","key":"10.1016\/j.jip.2026.108709_bb0125","doi-asserted-by":"crossref","DOI":"10.1128\/spectrum.00070-23","article-title":"Essential role of WetA, but no role of VosA, in asexual development, conidial maturation and insect pathogenicity of Metarhizium robertsii","volume":"11","author":"Zhang","year":"2023","journal-title":"Microbiol. Spectrum"}],"container-title":["Journal of Invertebrate Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022201126001850?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022201126001850?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,6]],"date-time":"2026-09-06T04:58:08Z","timestamp":1788670688000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022201126001850"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,11]]},"references-count":25,"alternative-id":["S0022201126001850"],"URL":"https:\/\/doi.org\/10.1016\/j.jip.2026.108709","relation":{},"ISSN":["0022-2011"],"issn-type":[{"value":"0022-2011","type":"print"}],"subject":[],"published":{"date-parts":[[2026,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Dual regulatory roles of the zinc cluster transcription factor MrFTRP1 in development, stress tolerance, and virulence of Metarhizium robertsii","name":"articletitle","label":"Article Title"},{"value":"Journal of Invertebrate Pathology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jip.2026.108709","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"108709"}}