{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T13:45:17Z","timestamp":1777297517578,"version":"3.51.4"},"reference-count":30,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,5,17]],"date-time":"2023-05-17T00:00:00Z","timestamp":1684281600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100005088","name":"Beijing Municipal Health Commission","doi-asserted-by":"publisher","award":["2020-1-1041"],"award-info":[{"award-number":["2020-1-1041"]}],"id":[{"id":"10.13039\/501100005088","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005088","name":"Beijing Municipal Health Commission","doi-asserted-by":"publisher","award":["DFL20191601"],"award-info":[{"award-number":["DFL20191601"]}],"id":[{"id":"10.13039\/501100005088","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005088","name":"Beijing Municipal Health Commission","doi-asserted-by":"publisher","award":["ZYLX202122"],"award-info":[{"award-number":["ZYLX202122"]}],"id":[{"id":"10.13039\/501100005088","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Infection and Public Health"],"published-print":{"date-parts":[[2023,8]]},"DOI":"10.1016\/j.jiph.2023.05.020","type":"journal-article","created":{"date-parts":[[2023,5,24]],"date-time":"2023-05-24T21:14:04Z","timestamp":1684962844000},"page":"1193-1200","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["Transmission and resistome of extremely drug-resistant tuberculosis in Beijing, China: A retrospective population-based epidemiological study"],"prefix":"10.1016","volume":"16","author":[{"given":"Haiping","family":"Guo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"An","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shanshan","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beichuan","family":"Ding","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhiguo","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Shu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuanyuan","family":"Shang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ken","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yufeng","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhongtan","family":"Xue","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weicong","family":"Ren","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junhua","family":"Pan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tao","family":"Luo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu","family":"Pang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jiph.2023.05.020_bib1","unstructured":"World Health Organization. Global tuberculosis report 2020. Geneva: WHO 2020. \u3008https:\/\/www.who.int\/tb\/publications\/gloable_report\/en\/\u3009."},{"key":"10.1016\/j.jiph.2023.05.020_bib2","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/S1473-3099(17)30703-X","article-title":"The global burden of tuberculosis: results from the Global Burden of Disease Study 2015","volume":"18","author":"Collaborators","year":"2018","journal-title":"Lancet Infect Dis"},{"issue":"Suppl 3","key":"10.1016\/j.jiph.2023.05.020_bib3","doi-asserted-by":"crossref","first-page":"S201","DOI":"10.1086\/651492","article-title":"HIV infection-associated tuberculosis: the epidemiology and the response","volume":"50","author":"Getahun","year":"2010","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.jiph.2023.05.020_bib4","doi-asserted-by":"crossref","first-page":"1830","DOI":"10.1016\/S0140-6736(10)60410-2","article-title":"Multidrug-resistant and extensively drug-resistant tuberculosis: a threat to global control of tuberculosis","volume":"375","author":"Gandhi","year":"2010","journal-title":"Lancet"},{"key":"10.1016\/j.jiph.2023.05.020_bib5","unstructured":"World Health Organization. Global tuberculosis report 2019. Geneva: WHO 2019. \u3008https:\/\/www.who.int\/tb\/publications\/global_report\/en\/\u3009."},{"key":"10.1016\/j.jiph.2023.05.020_bib6","doi-asserted-by":"crossref","first-page":"1377","DOI":"10.1016\/j.cmi.2019.03.022","article-title":"Role and value of whole genome sequencing in studying tuberculosis transmission","volume":"25","author":"Nikolayevskyy","year":"2019","journal-title":"Clin Microbiol Infect"},{"key":"10.1016\/j.jiph.2023.05.020_bib7","first-page":"4","article-title":"Large-scale whole genome sequencing of M. tuberculosis provides insights into transmission in a high prevalence area","author":"Guerra-Assuncao","year":"2015","journal-title":"Elife"},{"key":"10.1016\/j.jiph.2023.05.020_bib8","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/S1473-3099(16)30418-2","article-title":"Transmission of multidrug-resistant Mycobacterium tuberculosis in Shanghai, China: a retrospective observational study using whole-genome sequencing and epidemiological investigation","volume":"17","author":"Yang","year":"2017","journal-title":"Lancet Infect Dis"},{"key":"10.1016\/j.jiph.2023.05.020_bib9","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/S1473-3099(12)70277-3","article-title":"Whole-genome sequencing to delineate Mycobacterium tuberculosis outbreaks: a retrospective observational study","volume":"13","author":"Walker","year":"2013","journal-title":"Lancet Infect Dis"},{"key":"10.1016\/j.jiph.2023.05.020_bib10","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pmed.1003933","article-title":"Phylogeography and transmission of M. tuberculosis in Moldova: A prospective genomic analysis","volume":"19","author":"Yang","year":"2022","journal-title":"PLoS Med"},{"key":"10.1016\/j.jiph.2023.05.020_bib11","first-page":"52","article-title":"Extensively drug-resistant tuberculosis in South Africa: genomic evidence supporting transmission in communities","author":"Auld","year":"2018","journal-title":"Eur Respir J"},{"key":"10.1016\/j.jiph.2023.05.020_bib12","doi-asserted-by":"crossref","first-page":"2161","DOI":"10.1056\/NEJMoa1108789","article-title":"National survey of drug-resistant tuberculosis in China","volume":"366","author":"Zhao","year":"2012","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jiph.2023.05.020_bib13","article-title":"Would you like to leave Beijing, Shanghai, or Shenzhen? An empirical analysis of migration effect in China","volume":"13","author":"Liu","year":"2018","journal-title":"PLoS One"},{"key":"10.1016\/j.jiph.2023.05.020_bib14","article-title":"Genotypic diversity analysis of Mycobacterium tuberculosis strains collected from Beijing in 2009, using spoligotyping and VNTR typing","volume":"9","author":"Liu","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.jiph.2023.05.020_bib15","doi-asserted-by":"crossref","first-page":"457","DOI":"10.3201\/eid2503.180572","article-title":"Epidemiology of extrapulmonary tuberculosis among inpatients, China, 2008-2017","volume":"25","author":"Pang","year":"2019","journal-title":"Emerg Infect Dis"},{"key":"10.1016\/j.jiph.2023.05.020_bib16","doi-asserted-by":"crossref","first-page":"e3391","DOI":"10.1093\/cid\/ciaa1002","article-title":"Reduced Susceptibility of Mycobacterium tuberculosis to Bedaquiline During Antituberculosis Treatment and Its Correlation With Clinical Outcomes in China","volume":"73","author":"Liu","year":"2021","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.jiph.2023.05.020_bib17","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1111\/resp.13143","article-title":"Recent controversies about MDR and XDR-TB: Global implementation of the WHO shorter MDR-TB regimen and bedaquiline for all with MDR-TB?","volume":"23","author":"Dheda","year":"2018","journal-title":"Respirology"},{"key":"10.1016\/j.jiph.2023.05.020_bib18","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1016\/j.cmi.2017.11.015","article-title":"Prevalence, associated factors, outcomes and transmission of extensively drug-resistant tuberculosis among multidrug-resistant tuberculosis patients in Sao Paulo, Brazil: a cross-sectional study","volume":"24","author":"Gallo","year":"2018","journal-title":"Clin Microbiol Infect"},{"key":"10.1016\/j.jiph.2023.05.020_bib19","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1016\/S1473-3099(13)70128-2","article-title":"Transmission of multidrug-resistant tuberculosis in the USA: a cross-sectional study","volume":"13","author":"Moonan","year":"2013","journal-title":"Lancet Infect Dis"},{"key":"10.1016\/j.jiph.2023.05.020_bib20","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/S2213-2600(14)70027-X","article-title":"Assessment of Mycobacterium tuberculosis transmission in Oxfordshire, UK, 2007-12, with whole pathogen genome sequences: an observational study","volume":"2","author":"Walker","year":"2014","journal-title":"Lancet Respir Med"},{"key":"10.1016\/j.jiph.2023.05.020_bib21","unstructured":"WHO consolidated guidelines on tuberculosis. Module 3: diagnosis-rapid diagnostics for tuberculosis detection, 2021 update. Geneva: World Health Organization; 2021. Licence: CC BY-NC-SA 3.0 IGO."},{"key":"10.1016\/j.jiph.2023.05.020_bib22","doi-asserted-by":"crossref","first-page":"1724","DOI":"10.1093\/infdis\/jis601","article-title":"Dynamic population changes in Mycobacterium tuberculosis during acquisition and fixation of drug resistance in patients","volume":"206","author":"Sun","year":"2012","journal-title":"J Infect Dis"},{"key":"10.1016\/j.jiph.2023.05.020_bib23","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1128\/AAC.00964-09","article-title":"Selection of mutations to detect multidrug-resistant Mycobacterium tuberculosis strains in Shanghai, China","volume":"54","author":"Luo","year":"2010","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.jiph.2023.05.020_bib24","doi-asserted-by":"crossref","first-page":"491","DOI":"10.3201\/eid2303.161034","article-title":"pncA gene mutations associated with pyrazinamide resistance in drug-resistant Tuberculosis, South Africa and Georgia","volume":"23","author":"Allana","year":"2017","journal-title":"Emerg Infect Dis"},{"key":"10.1016\/j.jiph.2023.05.020_bib25","doi-asserted-by":"crossref","first-page":"510","DOI":"10.3201\/eid1703.101363","article-title":"Increasing drug resistance in extensively drug-resistant tuberculosis, South Africa","volume":"17","author":"Shah","year":"2011","journal-title":"Emerg Infect Dis"},{"key":"10.1016\/j.jiph.2023.05.020_bib26","series-title":"Technical manual for drug susceptibility testing of medicines used in the treatment of tuberculosis","year":"2018"},{"key":"10.1016\/j.jiph.2023.05.020_bib27","first-page":"57","article-title":"How well do routine molecular diagnostics detect rifampin heteroresistance in Mycobacterium tuberculosis?","author":"Ng","year":"2019","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.jiph.2023.05.020_bib28","doi-asserted-by":"crossref","first-page":"87","DOI":"10.2147\/IDR.S181259","article-title":"Additional benefits of GeneXpert MTB\/RIF assay for the detection of pulmonary tuberculosis patients with prior exposure to fluoroquinolones","volume":"12","author":"Tang","year":"2019","journal-title":"Infect Drug Resist"},{"key":"10.1016\/j.jiph.2023.05.020_bib29","first-page":"63","article-title":"Reactive oxygen species production is a major factor directing the postantibiotic effect of fluoroquinolones in streptococcus pneumoniae","author":"Garcia","year":"2019","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.jiph.2023.05.020_bib30","unstructured":"World Health Organization. Meeting report of the WHO expert consultation on the defnition of extensively drug-resistant tuberculosis, 27\u201329 October 2020. Geneva: WHO; 2021."}],"container-title":["Journal of Infection and Public Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1876034123001752?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1876034123001752?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T15:17:55Z","timestamp":1761751075000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1876034123001752"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8]]},"references-count":30,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2023,8]]}},"alternative-id":["S1876034123001752"],"URL":"https:\/\/doi.org\/10.1016\/j.jiph.2023.05.020","relation":{},"ISSN":["1876-0341"],"issn-type":[{"value":"1876-0341","type":"print"}],"subject":[],"published":{"date-parts":[[2023,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Transmission and resistome of extremely drug-resistant tuberculosis in Beijing, China: A retrospective population-based epidemiological study","name":"articletitle","label":"Article Title"},{"value":"Journal of Infection and Public Health","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jiph.2023.05.020","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Author(s). Published by Elsevier Ltd on behalf of King Saud Bin Abdulaziz University for Health Sciences.","name":"copyright","label":"Copyright"}]}}