{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T18:57:59Z","timestamp":1788029879915,"version":"build-2784847793"},"reference-count":58,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,3,19]],"date-time":"2024-03-19T00:00:00Z","timestamp":1710806400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002383","name":"King Saud University","doi-asserted-by":"publisher","award":["RSPD2024R1035"],"award-info":[{"award-number":["RSPD2024R1035"]}],"id":[{"id":"10.13039\/501100002383","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Infection and Public Health"],"published-print":{"date-parts":[[2024,5]]},"DOI":"10.1016\/j.jiph.2024.03.023","type":"journal-article","created":{"date-parts":[[2024,3,22]],"date-time":"2024-03-22T06:50:08Z","timestamp":1711090208000},"page":"906-917","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"title":["Levofloxacin loaded chitosan and poly-lactic-co-glycolic acid nano-particles against resistant bacteria: Synthesis, characterization and antibacterial activity"],"prefix":"10.1016","volume":"17","author":[{"given":"Rabia","family":"Hayee","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehwish","family":"Iqtedar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norah A.","family":"Albekairi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdulrahman","family":"Alshammari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mauhammad Atif","family":"Makhdoom","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad","family":"Islam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadeem","family":"Ahmed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad Fawad","family":"Rasool","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chen","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hamid","family":"Saeed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.jiph.2024.03.023_bib1","first-page":"1879","article-title":"Antibiotic prescribing trends in patients with upper respiratory tract infections reporting to tertiary care hospitals of Lahore","volume":"33","author":"Ullah","year":"2020","journal-title":"Pak J Pharm Sci"},{"issue":"2","key":"10.1016\/j.jiph.2024.03.023_bib2","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.jconrel.2011.07.002","article-title":"Nanoantibiotics\u201d: a new paradigm for treating infectious diseases using nanomaterials in the antibiotics resistant era","volume":"156","author":"Huh","year":"2011","journal-title":"J Control Release"},{"issue":"1","key":"10.1016\/j.jiph.2024.03.023_bib3","first-page":"262","article-title":"Efficacy and safety of levofloxacin in the outpatient treatment of exacerbation of chronic obstructive pulmonary disease: levofloxacin 750 mg vs. levofloxacin 500 mg","volume":"4","author":"Minov","year":"2020","journal-title":"Eur J Respir Med"},{"key":"10.1016\/j.jiph.2024.03.023_bib4","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.phpro.2011.11.026","article-title":"Optimized preparation of levofloxacin-loaded chitosan nanoparticles by ionotropic gelation","volume":"22","author":"Guan","year":"2011","journal-title":"Phys Procedia"},{"issue":"5","key":"10.1016\/j.jiph.2024.03.023_bib5","first-page":"1041","article-title":"In vitro synergistic effect of ciprofloxacin with aminoglycosides against multidrug resistant-Pseudomonas aeruginosa","volume":"26","author":"Firdous","year":"2013","journal-title":"Pak J Pharm Sci"},{"issue":"12","key":"10.1016\/j.jiph.2024.03.023_bib6","doi-asserted-by":"crossref","first-page":"1368","DOI":"10.1016\/S1473-3099(18)30483-3","article-title":"Outbreak investigation of ceftriaxone-resistant Salmonella enterica serotype typhi and its risk factors among the general population in Hyderabad, Pakistan: a matched case-control study","volume":"18","author":"Qamar","year":"2018","journal-title":"Lancet Infect Dis"},{"issue":"2","key":"10.1016\/j.jiph.2024.03.023_bib7","doi-asserted-by":"crossref","first-page":"57","DOI":"10.3390\/pharmaceutics11020057","article-title":"Optimized preparation of levofloxacin loaded polymeric nanoparticles","volume":"11","author":"L\u00f3pez-L\u00f3pez","year":"2019","journal-title":"Pharmaceutics"},{"issue":"2","key":"10.1016\/j.jiph.2024.03.023_bib8","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.jsps.2011.01.004","article-title":"Preparation of a novel floating ring capsule-type dosage form for stomach specific delivery","volume":"19","author":"Mouzam","year":"2011","journal-title":"Saudi Pharm J"},{"issue":"3","key":"10.1016\/j.jiph.2024.03.023_bib9","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/j.jconrel.2009.06.020","article-title":"A biodegradable filament for controlled drug delivery","volume":"139","author":"Mack","year":"2009","journal-title":"J Control Release"},{"issue":"1","key":"10.1016\/j.jiph.2024.03.023_bib10","first-page":"20","article-title":"Preparation of levofloxacin-chitosan sustained-release microsphere","volume":"32","author":"Qian","year":"2004","journal-title":"J Zheijiang Univ Tech"},{"issue":"1","key":"10.1016\/j.jiph.2024.03.023_bib11","doi-asserted-by":"crossref","first-page":"41","DOI":"10.4155\/tde.14.91","article-title":"PLGA: a unique polymer for drug delivery","volume":"6","author":"Kapoor","year":"2015","journal-title":"Ther Deliv"},{"issue":"3","key":"10.1016\/j.jiph.2024.03.023_bib12","doi-asserted-by":"crossref","first-page":"235","DOI":"10.3390\/polym10030235","article-title":"Chitosan based self-assembled nanoparticles in drug delivery","volume":"10","author":"Qui\u00f1ones","year":"2018","journal-title":"Polymers"},{"key":"10.1016\/j.jiph.2024.03.023_bib13","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1016\/j.ijbiomac.2017.11.170","article-title":"Formulation and optimization of levofloxacin loaded chitosan nanoparticle for ocular delivery: In-vitro characterization, ocular tolerance and antibacterial activity","volume":"108","author":"Ameeduzzafar","year":"2018","journal-title":"Int J Biol Macromol"},{"issue":"8","key":"10.1016\/j.jiph.2024.03.023_bib14","doi-asserted-by":"crossref","first-page":"1114","DOI":"10.2174\/1567201814666170316113432","article-title":"Gold nanoparticles conjugated levofloxacin: for improved antibacterial activity over levofloxacin alone","volume":"14","author":"Bagga","year":"2017","journal-title":"Curr Drug Deliv"},{"issue":"6","key":"10.1016\/j.jiph.2024.03.023_bib15","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.3390\/pharmaceutics14061275","article-title":"PLGA carriers for controlled release of levofloxacin in anti-tuberculosis therapy","volume":"14","author":"Antonov","year":"2022","journal-title":"Pharmaceutics"},{"issue":"1","key":"10.1016\/j.jiph.2024.03.023_bib16","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1007\/s10876-022-02232-7","article-title":"Bioactive luteolin entrapped chitosan-PLGA nanoparticles: formulation optimization to in-vivo preclinical evaluation.","volume":"34","author":"Zafar","year":"2023","journal-title":"J Clust Sci"},{"key":"10.1016\/j.jiph.2024.03.023_bib17","article-title":"Development of forskolin and rutin-loaded polymeric nanoparticles for enhancement of topical ocular delivery: optimization, in-vitro, ex-vivo, and toxicity evaluation.","volume":"82","author":"Dahiya","year":"2023","journal-title":"J Drug Deliv Sci Tech"},{"key":"10.1016\/j.jiph.2024.03.023_bib18","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1016\/j.ijbiomac.2018.04.122","article-title":"Chitosan coated PLGA nanoparticles amplify the ocular hypotensive effect of forskolin: statistical design, characterization and in vivo studies.","volume":"116","author":"Khan","year":"2018","journal-title":"Int J Biol Macromol"},{"issue":"8","key":"10.1016\/j.jiph.2024.03.023_bib19","doi-asserted-by":"crossref","first-page":"1719","DOI":"10.3390\/pharmaceutics14081719","article-title":"Moringa concanensis-mediated synthesis and characterizations of ciprofloxacin encapsulated into Ag\/TiO2\/Fe2O3\/CS nanocomposite: a therapeutic solution against multidrug resistant E. coli strains of livestock infectious diseases","volume":"14","author":"Zafar","year":"2022","journal-title":"Pharmaceutics"},{"issue":"11","key":"10.1016\/j.jiph.2024.03.023_bib20","doi-asserted-by":"crossref","first-page":"3152","DOI":"10.3390\/nano11113152","article-title":"Ciprofloxacin-loaded gold nanoparticles against antimicrobial resistance: an in vivo assessment","volume":"11","author":"Nawaz","year":"2021","journal-title":"Nanomaterials"},{"issue":"7","key":"10.1016\/j.jiph.2024.03.023_bib21","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.3390\/medicina59071215","article-title":"Antibiotic susceptibility surveillance in the Punjab province of Pakistan: findings and implications","volume":"59","author":"Saleem","year":"2023","journal-title":"Medicina"},{"key":"10.1016\/j.jiph.2024.03.023_bib22","unstructured":"Institute for Health Metrices and Evaluation. The burden of antimicrobial resistance (AMR) in Pakistan. 2019. https:\/\/www.healthdata.org\/sites\/default\/files\/files\/Projects\/GRAM\/Pakistan_0.pdf (Accessed 7 March 2024)."},{"issue":"7","key":"10.1016\/j.jiph.2024.03.023_bib23","doi-asserted-by":"crossref","first-page":"14","DOI":"10.22159\/ijpps.2019v11i7.33375","article-title":"Chitosan nanoparticles as drug delivery system for cephalexin and its antimicrobial activity against multiidrug resistent bacteria","volume":"11","author":"Elassal","year":"2019","journal-title":"Int J Pharm Pharm Sci"},{"issue":"2","key":"10.1016\/j.jiph.2024.03.023_bib24","doi-asserted-by":"crossref","first-page":"114","DOI":"10.4103\/0973-8398.84552","article-title":"Formulation and characterization of levofloxacin-loaded biodegradable nanoparticles","volume":"5","author":"Gevariya","year":"2014","journal-title":"Asian J Pharm"},{"issue":"2","key":"10.1016\/j.jiph.2024.03.023_bib25","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.ijpharm.2015.10.057","article-title":"Double emulsion solvent evaporation techniques used for drug encapsulation","volume":"496","author":"Iqbal","year":"2015","journal-title":"Int J Pharm"},{"issue":"1","key":"10.1016\/j.jiph.2024.03.023_bib26","doi-asserted-by":"crossref","first-page":"1","DOI":"10.4103\/1735-5362.199041","article-title":"Development of a nanoprecipitation method for the entrapment of a very water soluble drug into Eudragit RL nanoparticles","volume":"12","author":"Salatin","year":"2017","journal-title":"Res Pharm Sci"},{"issue":"9","key":"10.1016\/j.jiph.2024.03.023_bib27","first-page":"168","article-title":"A key approach on dissolution of pharmaceutical dosage forms","volume":"6","author":"Hasan","year":"2017","journal-title":"Pharm Innov J"},{"key":"10.1016\/j.jiph.2024.03.023_bib28","article-title":"A review of in vitro drug release test methods for nano-sized dosage forms.","volume":"2014","author":"D\u2019Souza","year":"2014","journal-title":"Adv Pharm"},{"issue":"3","key":"10.1016\/j.jiph.2024.03.023_bib29","first-page":"80","article-title":"Prevalence and antimicrobial susceptibility patterns of bloodstream isolates at Jordan hospital intensive care unit: three years experience","volume":"18","author":"Wadi","year":"2011","journal-title":"J R Med Serv"},{"issue":"03","key":"10.1016\/j.jiph.2024.03.023_bib30","doi-asserted-by":"crossref","first-page":"299","DOI":"10.4103\/JLP.JLP_118_17","article-title":"Direct identification and susceptibility testing of Gram-negative bacilli from turbid urine samples using VITEK2","volume":"10","author":"Angaali","year":"2018","journal-title":"J Lab Physicians"},{"key":"10.1016\/j.jiph.2024.03.023_bib31","unstructured":"Hudzicki J. Kirby-Bauer disk diffusion susceptibility test protocol. American Society for Microbiology, 2009. https:\/\/asm.org\/protocols\/kirby-bauer-disk-diffusion-susceptibility-test-pro (Accessed 6 March 2024)."},{"issue":"11","key":"10.1016\/j.jiph.2024.03.023_bib32","first-page":"624","article-title":"Preparation, standardization of antibiotic discs and study of resistance pattern for first-line antibiotics in isolates from clinical samples","volume":"1","author":"Vineetha","year":"2015","journal-title":"Int J Appl Res"},{"issue":"10","key":"10.1016\/j.jiph.2024.03.023_bib33","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s11051-015-3191-2","article-title":"Synthesis, characterization, and cytotoxicity in human erythrocytes of multifunctional, magnetic, and luminescent nanocrystalline rare earth fluorides","volume":"17","author":"Grzyb","year":"2015","journal-title":"J Nanopart Res"},{"issue":"4","key":"10.1016\/j.jiph.2024.03.023_bib34","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1007\/s12247-016-9252-y","article-title":"Improved lung concentration of levofloxacin by targeted gelatin microspheres: In vivo pharmacokinetic evaluation of intake rate, targeting efficacy parameters and peak concentration ratio in albino mice.","volume":"11","author":"Ramaiah","year":"2016","journal-title":"J Pharm Innov"},{"issue":"18","key":"10.1016\/j.jiph.2024.03.023_bib35","doi-asserted-by":"crossref","first-page":"2870","DOI":"10.1080\/01496395.2018.1489845","article-title":"Chitosan nanoparticles extracted from shrimp shells, application for removal of Fe (II) and Mn (II) from aqueous phases","volume":"53","author":"Ali","year":"2018","journal-title":"Sep Sci Technol"},{"key":"10.1016\/j.jiph.2024.03.023_bib36","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1590\/s2175-97902022e20484","article-title":"Antibiotic susceptibility patterns of bacterial isolates of patients with upper respiratory tract infections","volume":"58","author":"Ullah","year":"2022","journal-title":"Braz J Pharm Sci"},{"key":"10.1016\/j.jiph.2024.03.023_bib37","doi-asserted-by":"crossref","DOI":"10.3389\/fchem.2021.687660","article-title":"Nanoantibiotics: functions and properties at the nanoscale to combat antibiotic resistance","volume":"9","author":"Mamun","year":"2021","journal-title":"Front Chem"},{"issue":"48","key":"10.1016\/j.jiph.2024.03.023_bib38","article-title":"Gram\u2010negative bacteria targeting mediated by carbohydrate\u2013carbohydrate interactions induced by surface\u2010modified nanoparticles","volume":"29","author":"Capeletti","year":"2019","journal-title":"Adv Funct Mater"},{"issue":"6","key":"10.1016\/j.jiph.2024.03.023_bib39","doi-asserted-by":"crossref","first-page":"2165","DOI":"10.1002\/jps.23087","article-title":"Optimization, in vitro \u2013in vivo evaluation, and short-term tolerability of novel levofloxacin-loaded PLGA nanoparticle formulation.","volume":"101","author":"Kumar","year":"2012","journal-title":"J Pharm Sci"},{"issue":"3","key":"10.1016\/j.jiph.2024.03.023_bib40","doi-asserted-by":"crossref","first-page":"21","DOI":"10.3390\/jfb7030021","article-title":"pH-responsive PLGA nanoparticle for controlled payload delivery of diclofenac sodium","volume":"7","author":"Khanal","year":"2016","journal-title":"J Funct Biomater"},{"issue":"2","key":"10.1016\/j.jiph.2024.03.023_bib41","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.flm.2018.07.003","article-title":"Synthesis of chitosan nanoparticles by TPP and their potential mosquito larvicidal application","volume":"2","author":"Anand","year":"2018","journal-title":"Front Lab Med"},{"key":"10.1016\/j.jiph.2024.03.023_bib42","doi-asserted-by":"crossref","first-page":"4","DOI":"10.3389\/fbioe.2020.00004","article-title":"Stable chitosan-based nanoparticles using polyphosphoric acid or hexametaphosphate for tandem ionotropic\/covalent crosslinking and subsequent investigation as novel vehicles for drug delivery","volume":"8","author":"Saeed","year":"2020","journal-title":"Front Bioeng Biotechnol"},{"issue":"1","key":"10.1016\/j.jiph.2024.03.023_bib43","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1080\/15685551.2022.2054117","article-title":"Synthesis and evaluation of chitosan based controlled release nanoparticles for the delivery of ticagrelor","volume":"25","author":"Shahid","year":"2022","journal-title":"Des Monomers Polym"},{"key":"10.1016\/j.jiph.2024.03.023_bib44","article-title":"Alphastatin-loaded chitosan nanoparticle preparation and its antiangiogenic effect on lung carcinoma","volume":"2019","author":"Zhang","year":"2019","journal-title":"Int J Polyem Sci"},{"issue":"3","key":"10.1016\/j.jiph.2024.03.023_bib45","doi-asserted-by":"crossref","DOI":"10.1128\/AAC.02134-16","article-title":"Population pharmacokinetics and pharmacodynamics of levofloxacin in acutely hospitalized older patients with various degrees of renal function","volume":"61","author":"Cojutti","year":"2017","journal-title":"Antimicrob Agent Chemother"},{"issue":"12","key":"10.1016\/j.jiph.2024.03.023_bib46","doi-asserted-by":"crossref","first-page":"306","DOI":"10.22317\/jcms.12201704","article-title":"Effect of formulation parameters on the size of PLGA nanoparticles encapsulating bovine serum albumin: a response surface methodology","volume":"3","author":"Adebileje","year":"2017","journal-title":"J Conte Med Sci"},{"issue":"8","key":"10.1016\/j.jiph.2024.03.023_bib47","doi-asserted-by":"crossref","first-page":"4218","DOI":"10.1039\/C9RA10857B","article-title":"PLGA nanoparticle preparations by emulsification and nanoprecipitation techniques: effects of formulation parameters","volume":"10","author":"Hern\u00e1ndez-Giottonini","year":"2020","journal-title":"RSC Adv"},{"issue":"4","key":"10.1016\/j.jiph.2024.03.023_bib48","doi-asserted-by":"crossref","first-page":"403","DOI":"10.2478\/acph-2014-0032","article-title":"The influence of different formulations and process parameters during the preparation of drug-loaded PLGA microspheres evaluated by multivariate data analysis","volume":"64","author":"Vyslou\u017eil","year":"2014","journal-title":"Acta Pharm"},{"issue":"1","key":"10.1016\/j.jiph.2024.03.023_bib49","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/S0168-3659(02)00127-X","article-title":"Residual polyvinyl alcohol associated with poly (D, L-lactide-co-glycolide) nanoparticles affects their physical properties and cellular uptake","volume":"82","author":"Sahoo","year":"2002","journal-title":"J Control Release"},{"issue":"8","key":"10.1016\/j.jiph.2024.03.023_bib50","first-page":"717","article-title":"In vitro physicochemical characterization and short term in vivo tolerability study of ethionamide loaded PLGA nanoparticles: potentially effective agent for multidrug resistant tuberculosis.","volume":"28","author":"Kumar","year":"2011","journal-title":"J Micro"},{"key":"10.1016\/j.jiph.2024.03.023_bib51","doi-asserted-by":"crossref","first-page":"2891","DOI":"10.2147\/IJN.S380656","article-title":"Antiviral activity of chitosan nanoparticles encapsulating curcumin against hepatitis C virus genotype 4a in human hepatoma cell lines","volume":"17","author":"Loutfy","year":"2022","journal-title":"Int J Nanomed"},{"issue":"4","key":"10.1016\/j.jiph.2024.03.023_bib52","doi-asserted-by":"crossref","first-page":"53","DOI":"10.3390\/pharmaceutics9040053","article-title":"An overview of chitosan nanoparticles and its application in non-parenteral drug delivery","volume":"9","author":"Mohammed","year":"2017","journal-title":"Pharmaceutics"},{"issue":"1","key":"10.1016\/j.jiph.2024.03.023_bib53","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2021.e08674","article-title":"Drug release study of the chitosan-based nanoparticles","volume":"8","author":"Herdiana","year":"2022","journal-title":"Heliyon"},{"issue":"1","key":"10.1016\/j.jiph.2024.03.023_bib54","doi-asserted-by":"crossref","first-page":"31996","DOI":"10.3402\/nano.v7.31996","article-title":"Synthesis of protein-coated biocompatible methotrexate-loaded PLA-PEG-PLA nanoparticles for breast cancer treatment","volume":"7","author":"Massadeh","year":"2016","journal-title":"Nano Rev Exp"},{"issue":"3","key":"10.1016\/j.jiph.2024.03.023_bib55","doi-asserted-by":"crossref","first-page":"341","DOI":"10.5650\/jos.ess20299","article-title":"Effects of polyvinyl alcohol on drug release from nanocomposite particles using poly (L-lactide-co-glycolide)","volume":"70","author":"Takeuchi","year":"2021","journal-title":"J Ole Sci"},{"issue":"4","key":"10.1016\/j.jiph.2024.03.023_bib56","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/S1359-0286(02)00117-1","article-title":"Biodegradable nanoparticles for drug delivery and targeting","volume":"6","author":"Hans","year":"2002","journal-title":"Curr Opin Solid State Mater Sci"},{"issue":"12","key":"10.1016\/j.jiph.2024.03.023_bib57","doi-asserted-by":"crossref","first-page":"3282","DOI":"10.3390\/biomedicines10123282","article-title":"Bioengineered ciprofloxacin-loaded chitosan nanoparticles for the treatment of bovine mastitis","volume":"10","author":"Yadav","year":"2022","journal-title":"Biomedicines"},{"key":"10.1016\/j.jiph.2024.03.023_bib58","doi-asserted-by":"crossref","first-page":"1597","DOI":"10.1007\/s11095-010-0142-6","article-title":"Antibacterial efficacy of inhalable levofloxacin-loaded polymeric nanoparticles against E. coli biofilm cells: the effect of antibiotic release profile","volume":"27","author":"Cheow","year":"2010","journal-title":"Pharm Res"}],"container-title":["Journal of Infection and Public Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S187603412400100X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S187603412400100X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,4,28]],"date-time":"2024-04-28T08:14:23Z","timestamp":1714292063000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S187603412400100X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5]]},"references-count":58,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2024,5]]}},"alternative-id":["S187603412400100X"],"URL":"https:\/\/doi.org\/10.1016\/j.jiph.2024.03.023","relation":{},"ISSN":["1876-0341"],"issn-type":[{"value":"1876-0341","type":"print"}],"subject":[],"published":{"date-parts":[[2024,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Levofloxacin loaded chitosan and poly-lactic-co-glycolic acid nano-particles against resistant bacteria: Synthesis, characterization and antibacterial activity","name":"articletitle","label":"Article Title"},{"value":"Journal of Infection and Public Health","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jiph.2024.03.023","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Author(s). Published by Elsevier Ltd on behalf of King Saud Bin Abdulaziz University for Health Sciences.","name":"copyright","label":"Copyright"}]}}