{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T01:58:31Z","timestamp":1768442311072,"version":"3.49.0"},"reference-count":51,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,8,21]],"date-time":"2025-08-21T00:00:00Z","timestamp":1755734400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Infection and Public Health"],"published-print":{"date-parts":[[2025,10]]},"DOI":"10.1016\/j.jiph.2025.102941","type":"journal-article","created":{"date-parts":[[2025,8,24]],"date-time":"2025-08-24T05:34:24Z","timestamp":1756013664000},"page":"102941","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["The outcomes of cryptococcal disease in HIV-positive individuals following COVID-19 infection: A systematic review and meta-analysis"],"prefix":"10.1016","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7361-5271","authenticated-orcid":false,"given":"Israa Abdullah","family":"Malli","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah Ali","family":"Alqhtani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hannah Ghazi","family":"Abid","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Norah Ali","family":"Alqhtani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-1188-6555","authenticated-orcid":false,"given":"Ghaida Essa","family":"Alharbi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lamar Hassan","family":"Aboaljadiel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roza Khalid","family":"Alharbi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tala Habib","family":"Aletani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taif Mohammed","family":"Alamri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jiph.2025.102941_bib1","series-title":"StatPearls","article-title":"Acquired immune deficiency syndrome","author":"Waymack","year":"2025"},{"issue":"4","key":"10.1016\/j.jiph.2025.102941_bib2","doi-asserted-by":"crossref","first-page":"ofac097","DOI":"10.1093\/ofid\/ofac097","article-title":"Economic burden of fungal diseases in the United States","volume":"9","author":"Benedict","year":"2022","journal-title":"Open Forum Infect Dis"},{"key":"10.1016\/j.jiph.2025.102941_bib3","series-title":"WHO fungal priority pathogens list to guide research, development and public health action","author":"Organization","year":"2022"},{"key":"10.1016\/j.jiph.2025.102941_bib4","unstructured":"Organization, W.H. HIV and AIDS. 2024 [cited 2024 May 11]; Available from: https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/hiv-aids."},{"issue":"1","key":"10.1016\/j.jiph.2025.102941_bib5","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.tips.2021.10.004","article-title":"Update and latest advances in antiretroviral therapy","volume":"43","author":"Men\u00e9ndez-Arias","year":"2022","journal-title":"Trends Pharmacol Sci"},{"issue":"10","key":"10.1016\/j.jiph.2025.102941_bib6","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1258\/ijsa.2010.010182","article-title":"An update on cryptococcus among HIV-infected patients","volume":"21","author":"Warkentien","year":"2010","journal-title":"Int J STD AIDS"},{"key":"10.1016\/j.jiph.2025.102941_bib7","series-title":"Guidelines for diagnosing, preventing and managing cryptococcal disease among adults, adolescents and children living with HIV","author":"Organization","year":"2022"},{"issue":"12","key":"10.1016\/j.jiph.2025.102941_bib8","doi-asserted-by":"crossref","first-page":"1748","DOI":"10.1016\/S1473-3099(22)00499-6","article-title":"The global burden of HIV-associated cryptococcal infection in adults in 2020: a modelling analysis","volume":"22","author":"Rajasingham","year":"2022","journal-title":"Lancet Infect Dis"},{"issue":"4","key":"10.1016\/j.jiph.2025.102941_bib9","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1097\/QAD.0b013e328322ffc3","article-title":"The burden of HIV-associated cryptococcal disease","volume":"23","author":"Harrison","year":"2009","journal-title":"Aids"},{"issue":"1","key":"10.1016\/j.jiph.2025.102941_bib10","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/j.idc.2015.10.006","article-title":"Cryptococcosis","volume":"30","author":"Maziarz","year":"2016","journal-title":"Infect Dis Clin North Am"},{"issue":"8","key":"10.1016\/j.jiph.2025.102941_bib11","doi-asserted-by":"crossref","DOI":"10.3390\/v16081333","article-title":"Trends in Clinico-Epidemiological profile and outcomes of patients with HIV-Associated cryptococcal meningitis in Shanghai, China, 2013-2023","volume":"16","author":"Zhao","year":"2024","journal-title":"Viruses"},{"key":"10.1016\/j.jiph.2025.102941_bib12","series-title":"StatPearls","article-title":"Cryptococcus","author":"Mada","year":"2025"},{"key":"10.1016\/j.jiph.2025.102941_bib13","doi-asserted-by":"crossref","DOI":"10.3390\/pathogens12111303","article-title":"Cryptococcal meningoencephalitis in phenotypically normal patients","volume":"12","author":"Cumagun","year":"2023","journal-title":"Pathogens"},{"issue":"2","key":"10.1016\/j.jiph.2025.102941_bib14","doi-asserted-by":"crossref","first-page":"270","DOI":"10.4269\/ajtmh.23-0457","article-title":"Case report: cryptococcal meningitis in a previously immunocompetent patient with coronavirus disease 2019","volume":"110","author":"Kim","year":"2024","journal-title":"Am J Trop Med Hyg"},{"issue":"8","key":"10.1016\/j.jiph.2025.102941_bib15","doi-asserted-by":"crossref","first-page":"ofad420","DOI":"10.1093\/ofid\/ofad420","article-title":"Cryptococcal meningitis in young, immunocompetent patients: a Single-Center retrospective case series and review of the literature","volume":"10","author":"Stack","year":"2023","journal-title":"Open Forum Infect Dis"},{"key":"10.1016\/j.jiph.2025.102941_bib16","series-title":"StatPearls","article-title":"Cryptococcus","author":"MU","year":"2025"},{"key":"10.1016\/j.jiph.2025.102941_bib17","first-page":"5597473","article-title":"Cryptococcus neoformans meningoencephalitis in an immunocompetent patient after COVID-19 infection","volume":"2021","author":"Ghanem","year":"2021","journal-title":"Case Rep Infect Dis"},{"issue":"4","key":"10.1016\/j.jiph.2025.102941_bib18","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1007\/s15010-022-01805-y","article-title":"COVID-19-associated cryptococcus infection (CACI): a review of literature and clinical pearls","volume":"50","author":"Regalla","year":"2022","journal-title":"Infection"},{"key":"10.1016\/j.jiph.2025.102941_bib19","series-title":"StatPearls","article-title":"Features, evaluation, and treatment of coronavirus (COVID-19)","author":"Cascella","year":"2025"},{"issue":"15","key":"10.1016\/j.jiph.2025.102941_bib20","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1093\/cid\/ciaa248","article-title":"Dysregulation of immune response in patients with coronavirus 2019 (COVID-19) in Wuhan, China","volume":"71","author":"Qin","year":"2020","journal-title":"Clin Infect Dis"},{"issue":"2","key":"10.1016\/j.jiph.2025.102941_bib21","doi-asserted-by":"crossref","DOI":"10.3390\/v13020202","article-title":"COVID-19: a review on the novel coronavirus disease evolution, transmission, detection, control and prevention","volume":"13","author":"Sharma","year":"2021","journal-title":"Viruses"},{"key":"10.1016\/j.jiph.2025.102941_bib22","doi-asserted-by":"crossref","first-page":"4167","DOI":"10.2147\/IDR.S335711","article-title":"COVID-19, HIV-Associated cryptococcal meningitis, disseminated tuberculosis and acute ischaemic stroke: a fatal foursome","volume":"14","author":"Bongomin","year":"2021","journal-title":"Infect Drug Resist"},{"issue":"13","key":"10.1016\/j.jiph.2025.102941_bib23","doi-asserted-by":"crossref","first-page":"1320","DOI":"10.1177\/0956462420957528","article-title":"Hospital-acquired SARS-CoV-2 pneumonia in a person living with HIV","volume":"31","author":"Chiappe Gonzalez","year":"2020","journal-title":"Int J STD AIDS"},{"key":"10.1016\/j.jiph.2025.102941_bib24","series-title":"Global Tuberculosis Report","author":"Organization","year":"2023"},{"issue":"3","key":"10.1016\/j.jiph.2025.102941_bib25","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1007\/s10238-021-00751-7","article-title":"COVID-19-associated opportunistic infections: a snapshot on the current reports","volume":"22","author":"Abdoli","year":"2022","journal-title":"Clin Exp Med"},{"key":"10.1016\/j.jiph.2025.102941_bib26","doi-asserted-by":"crossref","first-page":"n71","DOI":"10.1136\/bmj.n71","article-title":"The PRISMA 2020 statement: an updated guideline for reporting systematic reviews","volume":"372","author":"Page","year":"2021","journal-title":"Bmj"},{"issue":"1","key":"10.1016\/j.jiph.2025.102941_bib27","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1186\/s13643-016-0384-4","article-title":"Rayyan\u2014a web and mobile app for systematic reviews","volume":"5","author":"Ouzzani","year":"2016","journal-title":"Syst Rev"},{"key":"10.1016\/j.jiph.2025.102941_bib28","author":"Wells","year":"2014","journal-title":"NewctleOtt Scale (NOS) Assess Qual Nonrandomised Stud MetaAnal"},{"issue":"1","key":"10.1016\/j.jiph.2025.102941_bib29","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1002\/jrsm.1411","article-title":"Risk-of-bias VISualization (robvis): an R package and shiny web app for visualizing risk-of-bias assessments","volume":"12","author":"McGuinness","year":"2021","journal-title":"Res Synth Methods"},{"issue":"8","key":"10.1016\/j.jiph.2025.102941_bib30","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1111\/myc.13476","article-title":"Cryptococcosis among hospitalised patients with COVID-19: a multicentre research network study","volume":"65","author":"Chastain","year":"2022","journal-title":"Mycoses"},{"issue":"11","key":"10.1016\/j.jiph.2025.102941_bib31","doi-asserted-by":"crossref","DOI":"10.3390\/jof8111234","article-title":"Characteristics and outcomes of cryptococcosis among patients with and without COVID-19","volume":"8","author":"Chastain","year":"2022","journal-title":"J Fungi"},{"issue":"Sp. 1","key":"10.1016\/j.jiph.2025.102941_bib32","doi-asserted-by":"crossref","first-page":"206","DOI":"10.7705\/biomedica.6872","article-title":"Meningeal cryptococcosis and SARS-CoV-2 infection in people living with HIV\/AIDS","volume":"43","author":"Messina","year":"2023","journal-title":"Biomedica"},{"issue":"105","key":"10.1016\/j.jiph.2025.102941_bib33","article-title":"Infecciones f\u00fangicas en pacientes con COVID-19","volume":"29","author":"Messina","year":"2021","journal-title":"ASEI"},{"issue":"3","key":"10.1016\/j.jiph.2025.102941_bib34","article-title":"Profile of newly diagnosed patients with HIV infection in North-Eastern Romania","volume":"59","author":"Loghin","year":"2023","journal-title":"Med (Kaunas)"},{"issue":"2","key":"10.1016\/j.jiph.2025.102941_bib35","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1093\/cid\/ciad551","article-title":"Description of cryptococcosis following SARS-CoV-2 infection: a disease survey through the mycosis study group education and research consortium (MSG-19)","volume":"78","author":"Walker","year":"2024","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.jiph.2025.102941_bib36","unstructured":"Collaboration, C., Review Manager (RevMan) [Computer program]. 2024, The Nordic Cochrane Centre, The Cochrane Collaboration: Copenhagen."},{"issue":"7414","key":"10.1016\/j.jiph.2025.102941_bib37","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1136\/bmj.327.7414.557","article-title":"Measuring inconsistency in meta-analyses","volume":"327","author":"Higgins","year":"2003","journal-title":"Bmj"},{"key":"10.1016\/j.jiph.2025.102941_bib38","author":"MapChart","year":"2024","journal-title":"MapChart Creat Your Own Cust Map"},{"key":"10.1016\/j.jiph.2025.102941_bib39","article-title":"Comprehensive meta-analysis (version 4.0) [computer software]","author":"Borenstein","year":"2024","journal-title":"Biostat Englewood NJ"},{"issue":"1","key":"10.1016\/j.jiph.2025.102941_bib40","doi-asserted-by":"crossref","first-page":"71","DOI":"10.3201\/eid0401.980109","article-title":"What makes cryptococcus neoformans a pathogen?","volume":"4","author":"Buchanan","year":"1998","journal-title":"Emerg Infect Dis"},{"issue":"9","key":"10.1016\/j.jiph.2025.102941_bib41","doi-asserted-by":"crossref","DOI":"10.3390\/microorganisms11092326","article-title":"Diagnosis and outcomes of fungal Co-Infections in COVID-19 infections: a retrospective study","volume":"11","author":"Swaney","year":"2023","journal-title":"Microorganisms"},{"issue":"5","key":"10.1016\/j.jiph.2025.102941_bib42","doi-asserted-by":"crossref","first-page":"2971","DOI":"10.1002\/jmv.26828","article-title":"Clinical characteristics and outcomes of COVID-19 in people living with HIV in Belgium: a multicenter, retrospective cohort","volume":"93","author":"Nasreddine","year":"2021","journal-title":"J Med Virol"},{"key":"10.1016\/j.jiph.2025.102941_bib43","doi-asserted-by":"crossref","first-page":"3991","DOI":"10.2147\/IDR.S277899","article-title":"HIV and SARS-CoV-2 Co-Infection: what are the risks?","volume":"14","author":"Squillace","year":"2021","journal-title":"Infect Drug Resist"},{"issue":"7","key":"10.1016\/j.jiph.2025.102941_bib44","doi-asserted-by":"crossref","DOI":"10.3390\/jof7070545","article-title":"Risk factors for fungal co-Infections in critically ill COVID-19 patients, with a focus on immunosuppressants","volume":"7","author":"Ezeokoli","year":"2021","journal-title":"J Fungi"},{"key":"10.1016\/j.jiph.2025.102941_bib45","doi-asserted-by":"crossref","first-page":"1339911","DOI":"10.3389\/ffunb.2024.1339911","article-title":"Healthcare-associated fungal infections and emerging pathogens during the COVID-19 pandemic","volume":"5","author":"Shah","year":"2024","journal-title":"Front Fungal Biol"},{"issue":"9","key":"10.1016\/j.jiph.2025.102941_bib46","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0292062","article-title":"Using laboratory data to assess the impact of coronavirus (COVID-19) on reflex cryptococcal antigenaemia (CrAg) testing in South Africa","volume":"18","author":"Cassim","year":"2023","journal-title":"PLoS One"},{"key":"10.1016\/j.jiph.2025.102941_bib47","article-title":"Missed opportunities to identify cryptococcosis in COVID-19 patients: a case report and literature review","volume":"9","author":"Chastain","year":"2022","journal-title":"Ther Adv Infect Dis"},{"issue":"1","key":"10.1016\/j.jiph.2025.102941_bib48","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgph.0001313","article-title":"A multicenter survey of asymptomatic cryptococcal antigenemia among patients with advanced HIV disease in Nigeria","volume":"3","author":"Oladele","year":"2023","journal-title":"PLOS Glob Public Health"},{"issue":"8","key":"10.1016\/j.jiph.2025.102941_bib49","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1016\/j.cmi.2023.04.016","article-title":"Impact of prior cryptococcal antigen screening on in-hospital mortality in cryptococcal meningitis or fungaemia among HIV-seropositive individuals in South Africa: a cross-sectional observational study","volume":"29","author":"Paccoud","year":"2023","journal-title":"Clin Microbiol Infect"},{"issue":"10","key":"10.1016\/j.jiph.2025.102941_bib50","doi-asserted-by":"crossref","first-page":"1719","DOI":"10.3201\/eid2110.150249","article-title":"Cluster of cryptococcus neoformans infections in intensive care unit, Arkansas, USA, 2013","volume":"21","author":"Vallabhaneni","year":"2015","journal-title":"Emerg Infect Dis"},{"issue":"7","key":"10.1016\/j.jiph.2025.102941_bib51","doi-asserted-by":"crossref","first-page":"e250","DOI":"10.1093\/cid\/ciac724","article-title":"Infectious diseases society of america guidelines on the treatment and management of patients with COVID-19 (September 2022)","volume":"78","author":"Bhimraj","year":"2024","journal-title":"Clin Infect Dis"}],"container-title":["Journal of Infection and Public Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1876034125002904?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1876034125002904?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,3]],"date-time":"2025-09-03T20:56:40Z","timestamp":1756933000000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1876034125002904"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10]]},"references-count":51,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2025,10]]}},"alternative-id":["S1876034125002904"],"URL":"https:\/\/doi.org\/10.1016\/j.jiph.2025.102941","relation":{},"ISSN":["1876-0341"],"issn-type":[{"value":"1876-0341","type":"print"}],"subject":[],"published":{"date-parts":[[2025,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The outcomes of cryptococcal disease in HIV-positive individuals following COVID-19 infection: A systematic review and meta-analysis","name":"articletitle","label":"Article Title"},{"value":"Journal of Infection and Public Health","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jiph.2025.102941","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Ltd on behalf of King Saud Bin Abdulaziz University for Health Sciences.","name":"copyright","label":"Copyright"}],"article-number":"102941"}}