{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T08:00:15Z","timestamp":1791273615085,"version":"4.1.0"},"reference-count":38,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2012,12,1]],"date-time":"2012-12-01T00:00:00Z","timestamp":1354320000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2012,12,1]],"date-time":"2012-12-01T00:00:00Z","timestamp":1354320000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2013,12,1]],"date-time":"2013-12-01T00:00:00Z","timestamp":1385856000000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"name":"Ministry of Health of P.R. China","award":["WKJ2011-2-014"],"award-info":[{"award-number":["WKJ2011-2-014"]}]},{"name":"Health Bureau of Zhejiang Province","award":["11-CX01"],"award-info":[{"award-number":["11-CX01"]}]},{"name":"Zhejiang Provincial Key Disciplinary Fields of Geriatrics Program"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","journal-of-cardiology.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Cardiology"],"published-print":{"date-parts":[[2012,12]]},"DOI":"10.1016\/j.jjcc.2012.08.003","type":"journal-article","created":{"date-parts":[[2012,9,1]],"date-time":"2012-09-01T13:32:45Z","timestamp":1346506365000},"page":"495-502","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":205,"title":["Therapeutic effect of forest bathing on human hypertension in the elderly"],"prefix":"10.1016","volume":"60","author":[{"given":"Gen-Xiang","family":"Mao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong-Bao","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao-Guang","family":"Lan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhi-Hua","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhuo-Mei","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ya-Zhen","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xi-Lian","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuan-Dong","family":"Lv","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guo-Fu","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Yan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jjcc.2012.08.003_bib0005","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1177\/147323000603400204","article-title":"The effects of exercise in forest and urban environments on sympathetic nervous activity of normal young adults","volume":"34","author":"Yamaguchi","year":"2006","journal-title":"J Int Med Res"},{"key":"10.1016\/j.jjcc.2012.08.003_bib0010","first-page":"187","article-title":"Urban versus rural environment\u2014any differences in aeroallergens sensitization in an allergic population of Cova da Beira, Portugal?","volume":"37","author":"Loureiro","year":"2005","journal-title":"Eur Ann Allergy Clin Immunol"},{"issue":"Suppl. 2","key":"10.1016\/j.jjcc.2012.08.003_bib0015","first-page":"S27","article-title":"Effects of phytoncides on blood pressure under restraint stress in SHRSP","volume":"31","author":"Kawakami","year":"2004","journal-title":"Clin Exp Pharmacol Physiol"},{"key":"10.1016\/j.jjcc.2012.08.003_bib0020","first-page":"116","article-title":"Air pollution as noxious environmental factor in the development of cardiovascular disease","volume":"67","author":"Hassing","year":"2009","journal-title":"Neth J Med"},{"key":"10.1016\/j.jjcc.2012.08.003_bib0025","doi-asserted-by":"crossref","first-page":"1919","DOI":"10.1289\/ehp.0900589","article-title":"Traffic-related air pollution, oxidative stress genes, and asthma (ECHRS)","volume":"117","author":"Castro-Giner","year":"2009","journal-title":"Environ Health Perspect"},{"key":"10.1016\/j.jjcc.2012.08.003_bib0030","doi-asserted-by":"crossref","first-page":"2755","DOI":"10.1161\/CIRCULATIONAHA.109.893461","article-title":"Cardiovascular effects of ambient particulate air pollution exposure","volume":"121","author":"Sun","year":"2010","journal-title":"Circulation"},{"key":"10.1016\/j.jjcc.2012.08.003_bib0035","doi-asserted-by":"crossref","first-page":"1706","DOI":"10.1289\/ehp.1103564","article-title":"Long-term urban particulate air pollution, traffic noise, and arterial blood pressure","volume":"119","author":"Fuks","year":"2011","journal-title":"Environ Health Perspect"},{"key":"10.1016\/j.jjcc.2012.08.003_bib0040","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1476-069X-10-92","article-title":"Exposure to road traffic and railway noise and associations with blood pressure and self-reported hypertension: a cohort study","volume":"10","author":"Sorensen","year":"2011","journal-title":"Environ Health"},{"key":"10.1016\/j.jjcc.2012.08.003_bib0045","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.jjcc.2011.11.002","article-title":"Ghrelin and cardiovascular diseases","volume":"59","author":"Kishimoto","year":"2012","journal-title":"J Cardiol"},{"key":"10.1016\/j.jjcc.2012.08.003_bib0050","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1007\/s12199-009-0091-z","article-title":"Trends in research related to \u201cShinrin-yoku\u201d (taking in the forest atmosphere or forest bathing) in Japan","volume":"15","author":"Tsunetsugu","year":"2010","journal-title":"Environ Health Prev Med"},{"key":"10.1016\/j.jjcc.2012.08.003_bib0055","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.puhe.2010.09.005","article-title":"Effect of forest bathing on physiological and psychological responses in young Japanese male subjects","volume":"125","author":"Lee","year":"2011","journal-title":"Public Health"},{"key":"10.1016\/j.jjcc.2012.08.003_bib0060","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1007\/s12199-008-0068-3","article-title":"Effect of forest bathing trips on human immune function","volume":"15","author":"Li","year":"2010","journal-title":"Environ Health Prev Med"},{"key":"10.1016\/j.jjcc.2012.08.003_bib0065","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1177\/03946320070200S202","article-title":"Forest bathing enhances human natural killer activity and expression of anti-cancer proteins","volume":"20","author":"Li","year":"2007","journal-title":"Int J Immunopathol Pharmacol"},{"key":"10.1016\/j.jjcc.2012.08.003_bib0070","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1097\/00005053-197910000-00004","article-title":"Profile of Mood States: the factors and their physiological correlates","volume":"167","author":"Pollock","year":"1979","journal-title":"J Nerv Ment Dis"},{"key":"10.1016\/j.jjcc.2012.08.003_bib0075","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1631\/jzus.B1001003","article-title":"Effect of enalapril on plasma homocysteine levels in patients with essential hypertension","volume":"11","author":"Fan","year":"2010","journal-title":"J Zhejiang Univ Sci B"},{"key":"10.1016\/j.jjcc.2012.08.003_bib0080","doi-asserted-by":"crossref","first-page":"13","DOI":"10.33549\/physiolres.931525","article-title":"The role of renin\u2013angiotensin system in prothrombotic state in essential hypertension","volume":"59","author":"Remkova","year":"2010","journal-title":"Physiol Res"},{"key":"10.1016\/j.jjcc.2012.08.003_bib0085","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1007\/s11906-011-0239-2","article-title":"Disorders of blood pressure regulation-role of catecholamine biosynthesis, release, and metabolism","volume":"14","author":"Currie","year":"2012","journal-title":"Curr Hypertens Rep"},{"key":"10.1016\/j.jjcc.2012.08.003_bib0090","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1146\/annurev.physiol.61.1.391","article-title":"Pathophysiology of endothelin in the cardiovascular system","volume":"61","author":"Miyauchi","year":"1999","journal-title":"Annu Rev Physiol"},{"key":"10.1016\/j.jjcc.2012.08.003_bib0095","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1161\/HYPERTENSIONAHA.111.173328","article-title":"Interleukin 6 underlies angiotensin II-induced hypertension and chronic renal damage","volume":"59","author":"Zhang","year":"2012","journal-title":"Hypertension"},{"key":"10.1016\/j.jjcc.2012.08.003_bib0100","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1007\/s10067-011-1921-0","article-title":"Managing cardiovascular risk in patients with chronic inflammatory diseases","volume":"31","author":"Haraoui","year":"2012","journal-title":"Clin Rheumatol"},{"key":"10.1016\/j.jjcc.2012.08.003_bib0105","doi-asserted-by":"crossref","first-page":"365","DOI":"10.2190\/PM.41.4.f","article-title":"Anxiety disorders, hypertension, and cardiovascular risk: a review","volume":"41","author":"Player","year":"2011","journal-title":"Int J Psychiatry Med"},{"key":"10.1016\/j.jjcc.2012.08.003_bib0110","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1016\/j.intimp.2007.06.012","article-title":"Angiotensin II-induced vasodilation via type 2 receptor: role of bradykinin and nitric oxide","volume":"8","author":"Yayama","year":"2008","journal-title":"Int Immunopharmacol"},{"key":"10.1016\/j.jjcc.2012.08.003_bib0115","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1007\/s10571-009-9368-4","article-title":"Anti-inflammatory effects of angiotensin receptor blockers in the brain and the periphery","volume":"29","author":"Benicky","year":"2009","journal-title":"Cell Mol Neurobiol"},{"key":"10.1016\/j.jjcc.2012.08.003_bib0120","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1016\/S1357-2725(02)00271-6","article-title":"Inflammation and angiotensin II","volume":"35","author":"Suzuki","year":"2003","journal-title":"Int J Biochem Cell Biol"},{"key":"10.1016\/j.jjcc.2012.08.003_bib0125","first-page":"RA194","article-title":"Angiotensin II and vascular inflammation","volume":"11","author":"Cheng","year":"2005","journal-title":"Med Sci Monit"},{"key":"10.1016\/j.jjcc.2012.08.003_bib0130","first-page":"152","article-title":"Inflammation in hypertension","volume":"15","author":"Savoia","year":"2006","journal-title":"Curr Opin Nephrol Hypertens"},{"key":"10.1016\/j.jjcc.2012.08.003_bib0135","doi-asserted-by":"crossref","first-page":"R1092","DOI":"10.1152\/ajpregu.00700.2002","article-title":"ANG II is involved in the LPS-induced production of proinflammatory cytokines in dehydrated rats","volume":"284","author":"Miyoshi","year":"2003","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"10.1016\/j.jjcc.2012.08.003_bib0140","doi-asserted-by":"crossref","first-page":"1927","DOI":"10.1089\/ars.2010.3721","article-title":"Mechanisms of cardiovascular remodeling in hyperhomocysteinemia","volume":"15","author":"Steed","year":"2011","journal-title":"Antioxid Redox Signal"},{"key":"10.1016\/j.jjcc.2012.08.003_bib0145","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1016\/j.phrs.2011.03.003","article-title":"The role of endothelin-1 in the pathogenesis of pulmonary arterial hypertension","volume":"63","author":"Shao","year":"2011","journal-title":"Pharmacol Res"},{"key":"10.1016\/j.jjcc.2012.08.003_bib0150","first-page":"38","article-title":"Effects of short-term forest bathing on human health in a broad-leaved evergreen forest in Zhejiang Province, China","volume":"25","author":"Mao","year":"2012","journal-title":"Biomed Environ Sci"},{"key":"10.1016\/j.jjcc.2012.08.003_bib0155","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1159\/000328696","article-title":"Endothelin in renal inflammation and hypertension","volume":"172","author":"Saleh","year":"2011","journal-title":"Contrib Nephrol"},{"key":"10.1016\/j.jjcc.2012.08.003_bib0160","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1007\/s004840050066","article-title":"The effect of exposure to negative air ions on the recovery of physiological responses after moderate endurance exercise","volume":"41","author":"Ryushi","year":"1998","journal-title":"Int J Biometeorol"},{"key":"10.1016\/j.jjcc.2012.08.003_bib0165","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1097\/JOM.0b013e3181ceff7a","article-title":"Effect of air pollution on blood pressure, blood lipids, and blood sugar: a population-based approach","volume":"52","author":"Chuang","year":"2010","journal-title":"J Occup Environ Med"},{"key":"10.1016\/j.jjcc.2012.08.003_bib0170","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1097\/EDE.0b013e3182452f1d","article-title":"Short-term effects of air pollution on pulse pressure among nonsmoking adults","volume":"23","author":"Chen","year":"2012","journal-title":"Epidemiology"},{"key":"10.1016\/j.jjcc.2012.08.003_bib0175","doi-asserted-by":"crossref","first-page":"963","DOI":"10.3109\/08958378.2010.503322","article-title":"Cardiac oxidative stress and dysfunction by fine concentrated ambient particles (CAPs) are mediated by angiotensin-II","volume":"22","author":"Ghelfi","year":"2005","journal-title":"Inhal Toxicol"},{"key":"10.1016\/j.jjcc.2012.08.003_bib0180","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1289\/ehp.7736","article-title":"Pollutant particles produce vasoconstriction and enhance MAPK signaling via angiotensin type I receptor","volume":"113","author":"Li","year":"2005","journal-title":"Environ Health Perspect"},{"key":"10.1016\/j.jjcc.2012.08.003_bib0185","doi-asserted-by":"crossref","first-page":"234","DOI":"10.4103\/1463-1741.80160","article-title":"Cardiovascular effects of environmental noise: research in Austria","volume":"13","author":"Lercher","year":"2011","journal-title":"Noise Health"},{"key":"10.1016\/j.jjcc.2012.08.003_bib0190","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.jjcc.2011.12.006","article-title":"Heart failure as an autonomic nervous system dysfunction","volume":"59","author":"Kishi","year":"2012","journal-title":"J Cardiol"}],"container-title":["Journal of Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0914508712001852?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0914508712001852?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T12:50:32Z","timestamp":1760273432000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0914508712001852"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,12]]},"references-count":38,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2012,12]]}},"alternative-id":["S0914508712001852"],"URL":"https:\/\/doi.org\/10.1016\/j.jjcc.2012.08.003","relation":{},"ISSN":["0914-5087"],"issn-type":[{"value":"0914-5087","type":"print"}],"subject":[],"published":{"date-parts":[[2012,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Therapeutic effect of forest bathing on human hypertension in the elderly","name":"articletitle","label":"Article Title"},{"value":"Journal of Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jjcc.2012.08.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2012 Japanese College of Cardiology. Published by Elsevier Ireland Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}