{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T18:03:18Z","timestamp":1775844198020,"version":"3.50.1"},"reference-count":29,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2013,2,1]],"date-time":"2013-02-01T00:00:00Z","timestamp":1359676800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,2,1]],"date-time":"2013-02-01T00:00:00Z","timestamp":1359676800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2014,2,1]],"date-time":"2014-02-01T00:00:00Z","timestamp":1391212800000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","journal-of-cardiology.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Cardiology"],"published-print":{"date-parts":[[2013,2]]},"DOI":"10.1016\/j.jjcc.2012.08.023","type":"journal-article","created":{"date-parts":[[2012,11,16]],"date-time":"2012-11-16T00:00:23Z","timestamp":1353024023000},"page":"144-148","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":26,"title":["Uric acid and high sensitive C-reactive protein are associated with subclinical thoracic aortic atherosclerosis"],"prefix":"10.1016","volume":"61","author":[{"given":"Mustafa","family":"G\u00fcr","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Durmu\u015f Y\u0131ld\u0131ray","family":"\u015eahin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zafer","family":"Elbasan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G\u00fclhan Y\u00fcksel","family":"Kalkan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ali","family":"Y\u0131ld\u0131z","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zekeriya","family":"Kaya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bet\u00fcl","family":"\u00d6zaltun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Murat","family":"\u00c7ayl\u0131","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jjcc.2012.08.023_bib0005","doi-asserted-by":"crossref","first-page":"1791","DOI":"10.1172\/JCI42344","article-title":"Uric acid transport and disease","volume":"120","author":"So","year":"2010","journal-title":"J Clin Invest"},{"key":"10.1016\/j.jjcc.2012.08.023_bib0010","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1097\/HJH.0b013e3282f240bf","article-title":"Uric acid stimulates vascular smooth muscle cell proliferation and oxidative stress via the vascular renin\u2013angiotensin system","volume":"26","author":"Corry","year":"2008","journal-title":"J Hypertens"},{"key":"10.1016\/j.jjcc.2012.08.023_bib0015","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1194\/jlr.M200407-JLR200","article-title":"Prooxidant and antioxidant properties of human serum ultrafiltrates toward LDL: important role of uric acid","volume":"44","author":"Patterson","year":"2003","journal-title":"J Lipid Res"},{"key":"10.1016\/j.jjcc.2012.08.023_bib0020","doi-asserted-by":"crossref","first-page":"7","DOI":"10.7326\/0003-4819-131-1-199907060-00003","article-title":"Serum uric acid and risk for cardiovascular disease and death: the Framingham Heart Study","volume":"131","author":"Culleton","year":"1999","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.jjcc.2012.08.023_bib0025","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jjcc.2011.11.001","article-title":"Biochemical markers in heart failure","volume":"59","author":"Sato","year":"2012","journal-title":"J Cardiol"},{"key":"10.1016\/j.jjcc.2012.08.023_bib0030","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1056\/NEJM199901073400103","article-title":"Carotid artery intima and media thickness as a risk factor of myocardial infarction and stroke in older adults","volume":"340","author":"O\u2019Leary","year":"1999","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jjcc.2012.08.023_bib0035","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.atherosclerosis.2007.03.008","article-title":"Uric acid level and its association with carotid intima\u2013media thickness in patients with hypertension","volume":"197","author":"Tavil","year":"2008","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.jjcc.2012.08.023_bib0040","doi-asserted-by":"crossref","first-page":"1276","DOI":"10.1111\/j.1742-1241.2005.00621.x","article-title":"Relationship of serum uric acid to measures of endothelial function and atherosclerosis in healthy adults","volume":"59","author":"Erdogan","year":"2005","journal-title":"Int J Clin Pract"},{"key":"10.1016\/j.jjcc.2012.08.023_bib0045","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/j.atherosclerosis.2004.10.012","article-title":"Interrelation between the extent of atherosclerosis in the thoracic aorta, carotid intima\u2013media thickness and the extent of coronary artery disease","volume":"179","author":"Rohani","year":"2005","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.jjcc.2012.08.023_bib0050","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.1016\/S0735-1097(02)01748-5","article-title":"Evaluation of carotid artery and aortic intima\u2013media thickness measurements for exclusion of significant coronary atherosclerosis in patients scheduled for heart valve surgery","volume":"39","author":"Belhassen","year":"2002","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jjcc.2012.08.023_bib0055","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.jpeds.2009.08.036","article-title":"Aortic intima media thickness is an early marker of atherosclerosis in children with type 1 diabetes mellitus","volume":"156","author":"Harrington","year":"2010","journal-title":"J Pediatr"},{"key":"10.1016\/j.jjcc.2012.08.023_bib0060","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/0002-9149(76)90491-4","article-title":"Problems in echocardiographic volume determinations: echocardiographic\u2013angiographic correlations in the presence of absence of asynergy","volume":"37","author":"Teichholz","year":"1976","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.jjcc.2012.08.023_bib0065","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/j.atherosclerosis.2009.09.013","article-title":"Relationship between common carotid intima\u2013media thickness and thoracic aortic calcification: the Multi-Ethnic Study of Atherosclerosis","volume":"209","author":"Takasu","year":"2010","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.jjcc.2012.08.023_bib0070","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1006\/jmcc.1998.0843","article-title":"Endothelial dysfunction in human disease","volume":"31","author":"Drexler","year":"1999","journal-title":"J Mol Cell Cardiol"},{"key":"10.1016\/j.jjcc.2012.08.023_bib0075","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1097\/00005344-199903000-00012","article-title":"Acute simultaneous stimulation of nitric oxide and oxygen radicals by angiotensin II in humans in vivo","volume":"33","author":"Dijkhorst-Oei","year":"1999","journal-title":"J Cardiovasc Pharmacol"},{"key":"10.1016\/j.jjcc.2012.08.023_bib0080","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.semnephrol.2004.09.007","article-title":"Uric acid as a mediator of endothelial dysfunction, inflammation, and vascular disease","volume":"25","author":"Kanellis","year":"2005","journal-title":"Semin Nephrol"},{"key":"10.1016\/j.jjcc.2012.08.023_bib0085","doi-asserted-by":"crossref","first-page":"1739","DOI":"10.1111\/j.1523-1755.2005.00273.x","article-title":"Hyperuricemia induces endothelial dysfunction","volume":"67","author":"Khosla","year":"2005","journal-title":"Kidney Int"},{"key":"10.1016\/j.jjcc.2012.08.023_bib0090","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.jjcc.2012.01.013","article-title":"The relationships among hyperuricemia, endothelial dysfunction, and cardiovascular diseases: molecular mechanisms and clinical implications","volume":"59","author":"Puddu","year":"2012","journal-title":"J Cardiol"},{"key":"10.1016\/j.jjcc.2012.08.023_bib0095","doi-asserted-by":"crossref","first-page":"6858","DOI":"10.1073\/pnas.78.11.6858","article-title":"Uric acid provides an antioxidant defense in humans against oxidant- and radical-caused aging and cancer: a hypothesis","volume":"78","author":"Ames","year":"1981","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.jjcc.2012.08.023_bib0100","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.1093\/ajcn\/54.6.1129s","article-title":"Serum urate as an antioxidant for ascorbic acid","volume":"54","author":"Sevanian","year":"1991","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.jjcc.2012.08.023_bib0105","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1111\/j.1540-8175.2006.00194.x","article-title":"Relationship between plasma total antioxidant capacity and thoracic aortic intima\u2013media thickness","volume":"23","author":"Demirbag","year":"2006","journal-title":"Echocardiography"},{"key":"10.1016\/j.jjcc.2012.08.023_bib0110","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.mrfmmm.2007.01.011","article-title":"Lymphocyte DNA damage is associated with increased aortic intima\u2013media thickness","volume":"617","author":"Gur","year":"2007","journal-title":"Mutat Res"},{"key":"10.1016\/j.jjcc.2012.08.023_bib0115","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1056\/NEJM199901143400207","article-title":"Atherosclerosis\u2014an inflamatory disease","volume":"340","author":"Ross","year":"1999","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jjcc.2012.08.023_bib0120","doi-asserted-by":"crossref","first-page":"836","DOI":"10.1056\/NEJM200003233421202","article-title":"C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women","volume":"342","author":"Ridker","year":"2000","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jjcc.2012.08.023_bib0150","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1016\/j.jjcc.2012.03.006","article-title":"Comparison of inflammatory markers between diabetic and nondiabetic ST segment elevation myocardial infarction","volume":"60","author":"Heo","year":"2012","journal-title":"J Cardiol"},{"key":"10.1016\/j.jjcc.2012.08.023_bib0130","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1253\/jcj.56.592","article-title":"Advances in transesophageal echocardiography for the evaluation of atherosclerotic lesions in thoracic aorta\u2014the effects of hypertension, hypercholesterolemia, and aging on atherosclerotic lesions","volume":"56","author":"Matsuzaki","year":"1992","journal-title":"Jpn Circ J"},{"key":"10.1016\/j.jjcc.2012.08.023_bib0135","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1016\/S0002-9149(99)00389-6","article-title":"Relation between low-density lipoprotein cholesterol and thoracic aortic atherosclerosis","volume":"84","author":"Tribouilloy","year":"1999","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.jjcc.2012.08.023_bib0140","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1016\/0002-8703(94)90122-8","article-title":"Evaluation of thoracic aortic atherosclerosis by transesophageal echocardiography","volume":"127","author":"Nishino","year":"1994","journal-title":"Am Heart J"},{"key":"10.1016\/j.jjcc.2012.08.023_bib0145","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1016\/j.amjcard.2005.10.021","article-title":"Association of body mass index, metabolic syndrome, and leukocyte count","volume":"97","author":"Desai","year":"2005","journal-title":"Am J Cardiol"}],"container-title":["Journal of Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0914508712002638?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0914508712002638?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T12:51:12Z","timestamp":1760273472000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0914508712002638"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,2]]},"references-count":29,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2013,2]]}},"alternative-id":["S0914508712002638"],"URL":"https:\/\/doi.org\/10.1016\/j.jjcc.2012.08.023","relation":{},"ISSN":["0914-5087"],"issn-type":[{"value":"0914-5087","type":"print"}],"subject":[],"published":{"date-parts":[[2013,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Uric acid and high sensitive C-reactive protein are associated with subclinical thoracic aortic atherosclerosis","name":"articletitle","label":"Article Title"},{"value":"Journal of Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jjcc.2012.08.023","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2012 Japanese College of Cardiology. Published by Elsevier Ireland Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}