{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T18:57:11Z","timestamp":1776884231415,"version":"3.51.2"},"reference-count":30,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T00:00:00Z","timestamp":1559347200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T00:00:00Z","timestamp":1559347200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,6,1]],"date-time":"2020-06-01T00:00:00Z","timestamp":1590969600000},"content-version":"vor","delay-in-days":366,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","journal-of-cardiology.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Cardiology"],"published-print":{"date-parts":[[2019,6]]},"DOI":"10.1016\/j.jjcc.2018.12.009","type":"journal-article","created":{"date-parts":[[2018,12,24]],"date-time":"2018-12-24T08:44:53Z","timestamp":1545641093000},"page":"470-478","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"title":["Bleeding and ischemic events during dual antiplatelet therapy after second-generation drug-eluting stent implantation in hemodialysis patients"],"prefix":"10.1016","volume":"73","author":[{"given":"Akiyoshi","family":"Shimizu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shinjo","family":"Sonoda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshitaka","family":"Muraoka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koshi","family":"Setoyama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Konosuke","family":"Inoue","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshiya","family":"Miura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reo","family":"Anai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshinori","family":"Sanuki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tetsu","family":"Miyamoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasushi","family":"Oginosawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuki","family":"Tsuda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masaru","family":"Araki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yutaka","family":"Otsuji","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jjcc.2018.12.009_bib0155","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.jcin.2013.09.008","volume":"7","author":"Valgimigli","year":"2014","journal-title":"JACC Cardiovasc Interv"},{"key":"10.1016\/j.jjcc.2018.12.009_bib0160","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1016\/j.jcin.2013.07.009","volume":"6","author":"Gada","year":"2013","journal-title":"JACC Cardiovasc Interv"},{"key":"10.1016\/j.jjcc.2018.12.009_bib0165","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1161\/CIRCULATIONAHA.108.808311","article-title":"Antiplatelet therapy and stent thrombosis after sirolimus-eluting stent implantation","volume":"119","author":"Kimura","year":"2009","journal-title":"Circulation"},{"key":"10.1016\/j.jjcc.2018.12.009_bib0170","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1007\/s12928-014-0306-0","article-title":"Primary percutaneous coronary intervention and bleeding risk in the era of drug-eluting stent: a long-term cohort study","volume":"30","author":"Tsuchida","year":"2015","journal-title":"Cardiovasc Interv Ther"},{"key":"10.1016\/j.jjcc.2018.12.009_bib0175","doi-asserted-by":"crossref","first-page":"1881","DOI":"10.1161\/CIRCULATIONAHA.116.023952","article-title":"A critical appraisal of aspirin in secondary prevention: is less more?","volume":"134","author":"Gargiulo","year":"2016","journal-title":"Circulation"},{"key":"10.1016\/j.jjcc.2018.12.009_bib0180","doi-asserted-by":"crossref","first-page":"2155","DOI":"10.1056\/NEJMoa1409312","article-title":"Twelve or 30 months of dual antiplatelet therapy after drug-eluting stents","volume":"371","author":"Mauri","year":"2014","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jjcc.2018.12.009_bib0185","doi-asserted-by":"crossref","first-page":"1735","DOI":"10.1001\/jama.2016.3775","article-title":"development and validation of a prediction rule for benefit and harm of dual antiplatelet therapy beyond 1 year after percutaneous coronary intervention","volume":"315","author":"Yeh","year":"2016","journal-title":"JAMA"},{"key":"10.1016\/j.jjcc.2018.12.009_bib0190","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1016\/S0140-6736(17)30397-5","article-title":"Derivation and validation of the predicting bleeding complications in patients undergoing stent implantation and subsequent dual antiplatelet therapy (PRECISE-DAPT) score: a pooled analysis of individual-patient datasets from clinical trials","volume":"389","author":"Costa","year":"2017","journal-title":"Lancet"},{"key":"10.1016\/j.jjcc.2018.12.009_bib0195","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1016\/j.jcin.2017.05.008","article-title":"DAPT duration after drug-eluting stent implantation: no news is good news","volume":"10","author":"Valgimigli","year":"2017","journal-title":"JACC Cardiovasc Interv"},{"key":"10.1016\/j.jjcc.2018.12.009_bib0200","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1016\/j.jjcc.2017.06.003","article-title":"Individualized antiplatelet therapy after drug-eluting stent deployment: Implication of clinical trials of different durations of dual antiplatelet therapy","volume":"70","author":"Nakamura","year":"2017","journal-title":"J Cardiol"},{"key":"10.1016\/j.jjcc.2018.12.009_bib0205","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.jjcc.2018.03.001","article-title":"Dual antiplatelet therapy after coronary stent implantation: Individualizing the optimal duration","volume":"72","author":"Lugo","year":"2018","journal-title":"J Cardiol"},{"key":"10.1016\/j.jjcc.2018.12.009_bib0210","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1007\/s00392-011-0347-7","article-title":"Impact of chronic kidney disease on the prognosis of patients undergoing percutaneous coronary interventions using drug-eluting stents","volume":"100","author":"Kaya","year":"2011","journal-title":"Clin Res Cardiol"},{"key":"10.1016\/j.jjcc.2018.12.009_bib0215","doi-asserted-by":"crossref","first-page":"262","DOI":"10.2215\/CJN.04430416","article-title":"Dual antiplatelet therapy and clinical outcomes after coronary drug-eluting stent implantation in patients on hemodialysis","volume":"12","author":"Chen","year":"2017","journal-title":"Clin J Am Soc Nephrol"},{"key":"10.1016\/j.jjcc.2018.12.009_bib0220","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.1016\/j.jacc.2015.06.1323","article-title":"Incidence, predictors, and impact of post-discharge bleeding after percutaneous coronary intervention","volume":"66","author":"G\u00e9n\u00e9reux","year":"2015","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jjcc.2018.12.009_bib0225","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1016\/j.jjcc.2016.05.017","article-title":"Frequency and predictors of bleeding events after 2nd generation drug-eluting stent implantation differ depending on time after implantation","volume":"69","author":"Honda","year":"2017","journal-title":"J Cardiol"},{"key":"10.1016\/j.jjcc.2018.12.009_bib0230","first-page":"E73","article-title":"Impact of chronic kidney disease on 2-year clinical outcomes in patients treated with 6-month or 24-month DAPT duration: An analysis from the PRODIGY trial","volume":"90","author":"Gargiulo","year":"2017","journal-title":"Catheter Cardiovasc Interv"},{"key":"10.1016\/j.jjcc.2018.12.009_bib0235","doi-asserted-by":"crossref","first-page":"445","DOI":"10.7326\/0003-4819-156-6-201203200-00007","article-title":"Effects of antiplatelet therapy on mortality and cardiovascular and bleeding outcomes in persons with chronic kidney disease: a systematic review and meta-analysis","volume":"156","author":"Palmer","year":"2012","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.jjcc.2018.12.009_bib0240","doi-asserted-by":"crossref","first-page":"2736","DOI":"10.1161\/CIRCULATIONAHA.110.009449","article-title":"Standardized bleeding definitions for cardiovascular clinical trials: a consensus report from the Bleeding Academic Research Consortium","volume":"123","author":"Mehran","year":"2011","journal-title":"Circulation"},{"key":"10.1016\/j.jjcc.2018.12.009_bib0245","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1007\/s12928-016-0447-4","article-title":"Impact of stent type and prolonged dual antiplatelet therapy on long-term clinical outcomes in hemodialysis patients with coronary artery disease","volume":"33","author":"Asami","year":"2018","journal-title":"Cardiovasc Interv Ther"},{"key":"10.1016\/j.jjcc.2018.12.009_bib0250","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1161\/01.STR.12.4.460","article-title":"Incidence of stroke in Shibata, Japan: 1976\u20131978","volume":"12","author":"Tanaka","year":"1981","journal-title":"Stroke"},{"key":"10.1016\/j.jjcc.2018.12.009_bib0255","article-title":"Gender and age differences in outcomes of patients with acute coronary syndromes referred for coronary angiography","author":"St\u00e4hli","year":"2018","journal-title":"Catheter Cardiovasc Interv"},{"key":"10.1016\/j.jjcc.2018.12.009_bib0260","doi-asserted-by":"crossref","first-page":"e005610","DOI":"10.1161\/JAHA.117.005610","article-title":"Cumulative exposure to high-sensitivity C-reactive protein predicts the risk of cardiovascular disease","volume":"6","author":"Wang","year":"2017","journal-title":"J Am Heart Assoc"},{"key":"10.1016\/j.jjcc.2018.12.009_bib0265","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1161\/CIRCULATIONAHA.106.628909","article-title":"Clinical relevance of C-reactive protein during follow-up of patients with acute coronary syndromes in the Aggrastat-to-Zocor Trial","volume":"114","author":"Stenvinkel","year":"2006","journal-title":"Circulation"},{"key":"10.1016\/j.jjcc.2018.12.009_bib0270","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1111\/j.0894-0959.2004.17603.x","article-title":"Serum albumin: relationship to inflammation and nutrition","volume":"17","author":"Don","year":"2004","journal-title":"Semin Dial"},{"key":"10.1016\/j.jjcc.2018.12.009_bib0275","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1253\/circj.CJ-17-0015","article-title":"Decreased serum albumin predicts bleeding events in patients on antiplatelet therapy after percutaneous coronary intervention","volume":"81","author":"Tatami","year":"2017","journal-title":"Circ J"},{"key":"10.1016\/j.jjcc.2018.12.009_bib0280","doi-asserted-by":"crossref","first-page":"900","DOI":"10.1016\/j.clnu.2015.06.003","article-title":"The impact of weight loss and low BMI on mortality of nursing home residents - Results from the nutritionDay in nursing homes","volume":"35","author":"Wirth","year":"2016","journal-title":"Clin Nutr"},{"key":"10.1016\/j.jjcc.2018.12.009_bib0285","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.ijcard.2016.09.004","article-title":"Impact of systolic blood pressure on hemorrhagic stroke in patients with coronary artery disease during anti-platelet therapy: The Japanese Coronary Artery Disease (JCAD) study","volume":"224","author":"Kai","year":"2016","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.jjcc.2018.12.009_bib0290","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1093\/ejcts\/ezx333","article-title":"2017 European Society of Cardiology (ESC) focused update on dual antiplatelet therapy in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS)","volume":"53","author":"Jeppsson","year":"2018","journal-title":"Eur J Cardiothorac Surg"},{"key":"10.1016\/j.jjcc.2018.12.009_bib0295","unstructured":"UMIN Clinical Trial Registry. www.umin.ac.jp\/ctr\/. Identifier: UMIN000019948."},{"key":"10.1016\/j.jjcc.2018.12.009_bib0300","unstructured":"UMIN Clinical Trial Registry. www.umin.ac.jp\/ctr\/. Identifier: UMIN000028023."}],"container-title":["Journal of Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0914508718303526?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0914508718303526?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T13:00:43Z","timestamp":1760274043000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0914508718303526"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6]]},"references-count":30,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2019,6]]}},"alternative-id":["S0914508718303526"],"URL":"https:\/\/doi.org\/10.1016\/j.jjcc.2018.12.009","relation":{},"ISSN":["0914-5087"],"issn-type":[{"value":"0914-5087","type":"print"}],"subject":[],"published":{"date-parts":[[2019,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Bleeding and ischemic events during dual antiplatelet therapy after second-generation drug-eluting stent implantation in hemodialysis patients","name":"articletitle","label":"Article Title"},{"value":"Journal of Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jjcc.2018.12.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Published by Elsevier Ltd on behalf of Japanese College of Cardiology.","name":"copyright","label":"Copyright"}]}}