{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T12:05:55Z","timestamp":1790683555153,"version":"4.1.0"},"reference-count":63,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,5,2]],"date-time":"2021-05-02T00:00:00Z","timestamp":1619913600000},"content-version":"vor","delay-in-days":121,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","award":["PJT 153113"],"award-info":[{"award-number":["PJT 153113"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["jlr.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Lipid Research"],"published-print":{"date-parts":[[2021]]},"DOI":"10.1016\/j.jlr.2021.100085","type":"journal-article","created":{"date-parts":[[2021,5,5]],"date-time":"2021-05-05T15:24:44Z","timestamp":1620228284000},"page":"100085","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":23,"special_numbering":"C","title":["Sar1b mutant mice recapitulate gastrointestinal abnormalities associated with chylomicron retention disease"],"prefix":"10.1016","volume":"62","author":[{"given":"Nickolas","family":"Auclair","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alain T.","family":"San\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lena","family":"Ahmarani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathalie","family":"Patey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8977-3629","authenticated-orcid":false,"given":"Jean-Fran\u00e7ois","family":"Beaulieu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noel","family":"Peretti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Schohraya","family":"Spahis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9983-7027","authenticated-orcid":false,"given":"Emile","family":"Levy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jlr.2021.100085_bib1","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1194\/jlr.R052415","article-title":"Insights from human congenital disorders of intestinal lipid metabolism","volume":"56","author":"Levy","year":"2015","journal-title":"J.\u00a0Lipid Res."},{"key":"10.1016\/j.jlr.2021.100085_bib2","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1016\/0016-5085(87)90133-8","article-title":"Malabsorption, hypocholesterolemia, and fat-filled enterocytes with increased intestinal apoprotein B. Chylomicron retention disease","volume":"92","author":"Roy","year":"1987","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jlr.2021.100085_bib3","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1016\/0016-5085(88)90471-4","article-title":"Chylomicron retention disease","volume":"94","author":"Bouma","year":"1988","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jlr.2021.100085_bib4","doi-asserted-by":"crossref","first-page":"D320","DOI":"10.2741\/Hussain","article-title":"Signposts in the assembly of chylomicrons","volume":"6","author":"Hussain","year":"2001","journal-title":"Front. Biosci."},{"key":"10.1016\/j.jlr.2021.100085_bib5","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1097\/01.mol.0000169347.53568.5a","article-title":"Intestinal lipoprotein assembly","volume":"16","author":"Hussain","year":"2005","journal-title":"Curr. Opin. Lipidol."},{"key":"10.1016\/j.jlr.2021.100085_bib6","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1038\/ng1145","article-title":"Mutations in a Sar1 GTPase of COPII vesicles are associated with lipid absorption disorders","volume":"34","author":"Jones","year":"2003","journal-title":"Nat. Genet."},{"key":"10.1016\/j.jlr.2021.100085_bib7","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.ymgme.2009.02.003","article-title":"Chylomicron retention disease: a long term study of two cohorts","volume":"97","author":"Peretti","year":"2009","journal-title":"Mol. Genet. Metab."},{"key":"10.1016\/j.jlr.2021.100085_bib8","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1242\/jcs.00215","article-title":"COPII proteins are required for Golgi fusion but not for endoplasmic reticulum budding of the pre-chylomicron transport vesicle","volume":"116","author":"Siddiqi","year":"2003","journal-title":"J.\u00a0Cell Sci."},{"key":"10.1016\/j.jlr.2021.100085_bib9","doi-asserted-by":"crossref","first-page":"10178","DOI":"10.1074\/jbc.M111.327247","article-title":"Phosphorylation of Sar1b protein releases liver fatty acid-binding protein from multiprotein complex in intestinal cytosol enabling it to bind to endoplasmic reticulum (ER) and bud the pre-chylomicron transport vesicle","volume":"287","author":"Siddiqi","year":"2012","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.jlr.2021.100085_bib10","doi-asserted-by":"crossref","first-page":"17974","DOI":"10.1074\/jbc.M610765200","article-title":"Liver fatty acid-binding protein initiates budding of pre-chylomicron transport vesicles from intestinal endoplasmic reticulum","volume":"282","author":"Neeli","year":"2007","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.jlr.2021.100085_bib11","doi-asserted-by":"crossref","first-page":"G659","DOI":"10.1152\/ajpgi.00228.2015","article-title":"Control of chylomicron export from the intestine","volume":"310","author":"Mansbach","year":"2016","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol."},{"key":"10.1016\/j.jlr.2021.100085_bib12","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.ymgme.2007.08.120","article-title":"Anderson or chylomicron retention disease: molecular impact of five mutations in the SAR1B gene on the structure and the functionality of Sar1b protein","volume":"93","author":"Charcosset","year":"2008","journal-title":"Mol. Genet. Metab."},{"key":"10.1016\/j.jlr.2021.100085_bib13","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1111\/j.1399-0004.2008.01069.x","article-title":"Anderson's disease (chylomicron retention disease): a new mutation in the SARA2 gene associated with muscular and cardiac abnormalities","volume":"74","author":"Silvain","year":"2008","journal-title":"Clin. Genet."},{"key":"10.1016\/j.jlr.2021.100085_bib14","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1097\/MPG.0b013e318183188f","article-title":"Novel missense mutations of SAR1B gene in an infant with chylomicron retention disease","volume":"48","author":"Treepongkaruna","year":"2009","journal-title":"J.\u00a0Pediatr. Gastroenterol. Nutr."},{"key":"10.1016\/j.jlr.2021.100085_bib15","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1750-1172-6-1","article-title":"Molecular analysis and intestinal expression of SAR1 genes and proteins in Anderson's disease (Chylomicron retention disease)","volume":"6","author":"Georges","year":"2011","journal-title":"Orphanet J. Rare Dis."},{"key":"10.1016\/j.jlr.2021.100085_bib16","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.gene.2012.09.117","article-title":"Novel mutations in SAR1B and MTTP genes in Tunisian children with chylomicron retention disease and abetalipoproteinemia","volume":"512","author":"Magnolo","year":"2013","journal-title":"Gene"},{"key":"10.1016\/j.jlr.2021.100085_bib17","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1152\/physrev.2001.81.1.153","article-title":"Small GTP-binding proteins","volume":"81","author":"Takai","year":"2001","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.jlr.2021.100085_bib18","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1016\/j.jacl.2019.05.013","article-title":"Novel mutations of SAR1B gene in four children with chylomicron retention disease","volume":"13","author":"Simone","year":"2019","journal-title":"J.\u00a0Clin. Lipidol."},{"key":"10.1016\/j.jlr.2021.100085_bib19","doi-asserted-by":"crossref","first-page":"2243","DOI":"10.1161\/ATVBAHA.117.310121","article-title":"Understanding chylomicron retention disease through Sar1b Gtpase gene disruption: insight from cell culture","volume":"37","author":"Sane","year":"2017","journal-title":"Arterioscler Thromb. Vasc. Biol."},{"key":"10.1016\/j.jlr.2021.100085_bib20","doi-asserted-by":"crossref","first-page":"4244","DOI":"10.1074\/jbc.M113.479980","article-title":"The endoplasmic reticulum coat protein II transport machinery coordinates cellular lipid secretion and cholesterol biosynthesis","volume":"289","author":"Fryer","year":"2014","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.jlr.2021.100085_bib21","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1007\/s00109-014-1247-x","article-title":"Animal model of Sar1b deficiency presents lipid absorption deficits similar to Anderson disease","volume":"93","author":"Levic","year":"2015","journal-title":"J.\u00a0Mol. Med. (Berl)"},{"key":"10.1016\/j.jlr.2021.100085_bib22","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/j.neuroscience.2020.09.044","article-title":"Inhibition of Sar1b, the gene implicated in chylomicron retention disease, impairs migration and morphogenesis of developing cortical neurons","volume":"449","author":"Li","year":"2020","journal-title":"Neuroscience"},{"key":"10.1016\/j.jlr.2021.100085_bib23","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1016\/S0022-2275(20)38593-X","article-title":"Intestinal apoB synthesis, lipids, and lipoproteins in chylomicron retention disease","volume":"28","author":"Levy","year":"1987","journal-title":"J.\u00a0Lipid Res."},{"key":"10.1016\/j.jlr.2021.100085_bib24","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.cca.2015.10.033","article-title":"Update on the molecular biology of dyslipidemias","volume":"454","author":"Ramasamy","year":"2016","journal-title":"Clin. Chim. Acta"},{"key":"10.1016\/j.jlr.2021.100085_bib25","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1016\/j.jnutbio.2014.01.004","article-title":"Sar1b transgenic male mice are more susceptible to high-fat diet-induced obesity, insulin insensitivity and intestinal chylomicron overproduction","volume":"25","author":"Levy","year":"2014","journal-title":"J.\u00a0Nutr. Biochem."},{"key":"10.1016\/j.jlr.2021.100085_bib26","doi-asserted-by":"crossref","first-page":"265","DOI":"10.3109\/00365517609055259","article-title":"Precipitation of plasma lipoproteins by PEG-6000 and its evaluation with electrophoresis and ultracentrifugation","volume":"36","author":"Vikari","year":"1976","journal-title":"Scand. J. Clin. Lab. Invest."},{"key":"10.1016\/j.jlr.2021.100085_bib27","doi-asserted-by":"crossref","first-page":"1755","DOI":"10.1194\/jlr.RA119000119","article-title":"SAR1B GTPase is necessary to protect intestinal cells from disorders of lipid homeostasis, oxidative stress, and inflammation","volume":"60","author":"Sane","year":"2019","journal-title":"J.\u00a0Lipid Res."},{"key":"10.1016\/j.jlr.2021.100085_bib28","doi-asserted-by":"crossref","first-page":"738","DOI":"10.5301\/jn.5000053","article-title":"C57BL\/6 and 129\/Sv mice: genetic difference to renal ischemia-reperfusion","volume":"25","author":"Lu","year":"2012","journal-title":"J.\u00a0Nephrol."},{"key":"10.1016\/j.jlr.2021.100085_bib29","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1177\/0300985813478213","article-title":"Salmonella enterica causes more severe inflammatory disease in C57\/BL6 Nramp1G169 mice than Sv129S6 mice","volume":"50","author":"Brown","year":"2013","journal-title":"Vet. Pathol."},{"key":"10.1016\/j.jlr.2021.100085_bib30","doi-asserted-by":"crossref","first-page":"371","DOI":"10.3389\/fphar.2020.00371","article-title":"Treatment with lipopolysaccharide induces distinct changes in metabolite profile and body weight in 129Sv and Bl6 mouse strains","volume":"11","author":"Piirsalu","year":"2020","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.jlr.2021.100085_bib31","doi-asserted-by":"crossref","first-page":"8686","DOI":"10.1073\/pnas.95.15.8686","article-title":"Knockout of the abetalipoproteinemia gene in mice: reduced lipoprotein secretion in heterozygotes and embryonic lethality in homozygotes","volume":"95","author":"Raabe","year":"1998","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.jlr.2021.100085_bib32","doi-asserted-by":"crossref","first-page":"2152","DOI":"10.1172\/JCI118269","article-title":"apo B gene knockout in mice results in embryonic lethality in homozygotes and neural tube defects, male infertility, and reduced HDL cholesterol ester and apo A-I transport rates in heterozygotes","volume":"96","author":"Huang","year":"1995","journal-title":"J.\u00a0Clin. Invest."},{"key":"10.1016\/j.jlr.2021.100085_bib33","doi-asserted-by":"crossref","first-page":"2389","DOI":"10.1073\/pnas.90.6.2389","article-title":"Targeted modification of the apolipoprotein B gene results in hypobetalipoproteinemia and developmental abnormalities in mice","volume":"90","author":"Homanics","year":"1993","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.jlr.2021.100085_bib34","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/S0168-9525(00)89008-3","article-title":"Death before birth: clues from gene knockouts and mutations","volume":"11","author":"Copp","year":"1995","journal-title":"Trends Genet."},{"key":"10.1016\/j.jlr.2021.100085_bib35","doi-asserted-by":"crossref","first-page":"1774","DOI":"10.1073\/pnas.92.5.1774","article-title":"Knockout of the mouse apolipoprotein B gene results in embryonic lethality in homozygotes and protection against diet-induced hypercholesterolemia in heterozygotes","volume":"92","author":"Farese","year":"1995","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.jlr.2021.100085_bib36","doi-asserted-by":"crossref","DOI":"10.1242\/bio.057232","article-title":"Ctdp1 deficiency leads to early embryonic lethality in mice and defects in cell cycle progression in MEFs","volume":"10","author":"Qiao","year":"2021","journal-title":"Biol. Open"},{"key":"10.1016\/j.jlr.2021.100085_bib37","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1152\/physrev.00040.2007","article-title":"Interpreting neonatal lethal phenotypes in mouse mutants: insights into gene function and human diseases","volume":"89","author":"Turgeon","year":"2009","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.jlr.2021.100085_bib38","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1093\/hmg\/8.5.723","article-title":"Embryonic lethality and vascular defects in mice lacking the Notch ligand Jagged1","volume":"8","author":"Xue","year":"1999","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.jlr.2021.100085_bib39","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1186\/1471-2164-14-568","article-title":"Global expression profiling reveals genetic programs underlying the developmental divergence between mouse and human embryogenesis","volume":"14","author":"Xue","year":"2013","journal-title":"BMC Genomics"},{"key":"10.1016\/j.jlr.2021.100085_bib40","first-page":"223","article-title":"Oestrogen excretion in mares in relation to various reproductive states","volume":"Suppl","author":"Hillman","year":"1975","journal-title":"J.\u00a0Reprod. Fertil."},{"key":"10.1016\/j.jlr.2021.100085_bib41","doi-asserted-by":"crossref","first-page":"1967","DOI":"10.1016\/S0022-2275(20)32420-2","article-title":"Apolipoprotein B-related gene expression and ultrastructural characteristics of lipoprotein secretion in mouse yolk sac during embryonic development","volume":"40","author":"Terasawa","year":"1999","journal-title":"J.\u00a0Lipid Res."},{"key":"10.1016\/j.jlr.2021.100085_bib42","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/S0022-2275(20)37621-5","article-title":"A\u00a0novel function for apolipoprotein B: lipoprotein synthesis in the yolk sac is critical for maternal-fetal lipid transport in mice","volume":"37","author":"Farese","year":"1996","journal-title":"J.\u00a0Lipid Res."},{"key":"10.1016\/j.jlr.2021.100085_bib43","doi-asserted-by":"crossref","first-page":"55271","DOI":"10.1074\/jbc.M411404200","article-title":"Human placenta secretes apolipoprotein B-100-containing lipoproteins","volume":"279","author":"Madsen","year":"2004","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.jlr.2021.100085_bib44","first-page":"59","article-title":"Maternal lipid metabolism and placental lipid transfer","volume":"65 Suppl 3","author":"Herrera","year":"2006","journal-title":"Horm. Res."},{"key":"10.1016\/j.jlr.2021.100085_bib45","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1002\/1520-7560(200005\/06)16:3<202::AID-DMRR116>3.0.CO;2-#","article-title":"Lipid metabolism in the fetus and the newborn","volume":"16","author":"Herrera","year":"2000","journal-title":"Diabetes Metab. Res. Rev."},{"key":"10.1016\/j.jlr.2021.100085_bib46","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1042\/BCJ20160582","article-title":"The evolving role of ubiquitin modification in endoplasmic reticulum-associated degradation","volume":"474","author":"Preston","year":"2017","journal-title":"Biochem. J."},{"key":"10.1016\/j.jlr.2021.100085_bib47","doi-asserted-by":"crossref","first-page":"3171","DOI":"10.1083\/jcb.201906047","article-title":"Protein quality control in the secretory pathway","volume":"218","author":"Sun","year":"2019","journal-title":"J.\u00a0Cell Biol."},{"key":"10.1016\/j.jlr.2021.100085_bib48","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.ceb.2018.04.004","article-title":"Mechanistic insights into ER-associated protein degradation","volume":"53","author":"Wu","year":"2018","journal-title":"Curr. Opin. Cell Biol."},{"key":"10.1016\/j.jlr.2021.100085_bib49","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0026206","article-title":"Endoplasmic reticulum quality control is involved in the mechanism of endoglin-mediated hereditary haemorrhagic telangiectasia","volume":"6","author":"Ali","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.jlr.2021.100085_bib50","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1007\/s11010-012-1496-3","article-title":"Retention in the endoplasmic reticulum is the underlying mechanism of some hereditary haemorrhagic telangiectasia type 2 ALK1 missense mutations","volume":"373","author":"Hume","year":"2013","journal-title":"Mol. Cell Biochem"},{"key":"10.1016\/j.jlr.2021.100085_bib51","doi-asserted-by":"crossref","first-page":"2684","DOI":"10.1172\/JCI31330","article-title":"A\u00a0homozygous missense mutation in human KLOTHO causes severe tumoral calcinosis","volume":"117","author":"Ichikawa","year":"2007","journal-title":"J.\u00a0Clin. Invest."},{"key":"10.1016\/j.jlr.2021.100085_bib52","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1042\/BSR20120046","article-title":"Protein instability and functional defects caused by mutations of dihydro-orotate dehydrogenase in Miller syndrome patients","volume":"32","author":"Fang","year":"2012","journal-title":"Biosci. Rep."},{"key":"10.1016\/j.jlr.2021.100085_bib53","first-page":"330","article-title":"[A severely disturbed lipid profile]","volume":"62","author":"Mignard","year":"2004","journal-title":"Ann. Biol. Clin. (Paris)"},{"key":"10.1016\/j.jlr.2021.100085_bib54","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0049159","article-title":"Intestine-specific Mttp deletion decreases mortality and prevents sepsis-induced intestinal injury in a murine model of Pseudomonas aeruginosa pneumonia","volume":"7","author":"Dominguez","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.jlr.2021.100085_bib55","doi-asserted-by":"crossref","first-page":"30432","DOI":"10.1074\/jbc.M113.501247","article-title":"Lipid absorption defects in intestine-specific microsomal triglyceride transfer protein and ATP-binding cassette transporter A1-deficient mice","volume":"288","author":"Iqbal","year":"2013","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.jlr.2021.100085_bib56","article-title":"Intestine-specific Mttp deletion increases the severity of experimental colitis and leads to greater tumor burden in a model of colitis associated cancer","volume":"8","author":"Xie","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.jlr.2021.100085_bib57","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1186\/1750-1172-5-24","article-title":"Guidelines for the diagnosis and management of chylomicron retention disease based on a review of the literature and the experience of two centers","volume":"5","author":"Peretti","year":"2010","journal-title":"Orphanet J. Rare Dis."},{"key":"10.1016\/j.jlr.2021.100085_bib58","doi-asserted-by":"crossref","first-page":"27799","DOI":"10.1038\/srep27799","article-title":"Bax Inhibitor-1 regulates hepatic lipid accumulation via ApoB secretion","volume":"6","author":"Lee","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jlr.2021.100085_bib59","doi-asserted-by":"crossref","first-page":"1377","DOI":"10.1152\/physrev.00050.2006","article-title":"In and out of the ER: protein folding, quality control, degradation, and related human diseases","volume":"87","author":"Hebert","year":"2007","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.jlr.2021.100085_bib60","doi-asserted-by":"crossref","first-page":"2561","DOI":"10.1161\/ATVBAHA.112.300135","article-title":"High density lipoprotein biogenesis, cholesterol efflux, and immune cell function","volume":"32","author":"Sorci-Thomas","year":"2012","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.jlr.2021.100085_bib61","doi-asserted-by":"crossref","first-page":"2813","DOI":"10.1161\/ATVBAHA.112.300133","article-title":"High-density lipoprotein function, dysfunction, and reverse cholesterol transport","volume":"32","author":"Fisher","year":"2012","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.jlr.2021.100085_bib62","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1161\/01.ATV.20.5.1309","article-title":"In\u00a0vivo metabolism of ApoB, ApoA-I, and VLDL triglycerides in a form of hypobetalipoproteinemia not linked to the ApoB gene","volume":"20","author":"Elias","year":"2000","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.jlr.2021.100085_bib63","doi-asserted-by":"crossref","first-page":"1809","DOI":"10.1016\/S0022-2275(20)39776-5","article-title":"In\u00a0vivo metabolism of apolipoproteins A-I and E in patients with abetalipoproteinemia: implications for the roles of apolipoproteins B and E in HDL metabolism","volume":"35","author":"Ikewaki","year":"1994","journal-title":"J.\u00a0Lipid Res."}],"container-title":["Journal of Lipid Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022227521000675?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022227521000675?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,2,17]],"date-time":"2022-02-17T10:01:04Z","timestamp":1645092064000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022227521000675"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021]]},"references-count":63,"alternative-id":["S0022227521000675"],"URL":"https:\/\/doi.org\/10.1016\/j.jlr.2021.100085","relation":{},"ISSN":["0022-2275"],"issn-type":[{"value":"0022-2275","type":"print"}],"subject":[],"published":{"date-parts":[[2021]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Sar1b mutant mice recapitulate gastrointestinal abnormalities associated with chylomicron retention disease","name":"articletitle","label":"Article Title"},{"value":"Journal of Lipid Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jlr.2021.100085","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 The Authors. Published by Elsevier Inc on behalf of American Society for Biochemistry and Molecular Biology.","name":"copyright","label":"Copyright"}],"article-number":"100085"}}