{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T20:32:48Z","timestamp":1793305968609,"version":"4.5.0"},"reference-count":57,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T00:00:00Z","timestamp":1787961600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100009108","name":"Shandong University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009108","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010029","name":"Taishan Scholar Foundation of Shandong Province","doi-asserted-by":"publisher","award":["LQ"],"award-info":[{"award-number":["LQ"]}],"id":[{"id":"10.13039\/501100010029","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82200303"],"award-info":[{"award-number":["82200303"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82300313"],"award-info":[{"award-number":["82300313"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["U23A6011"],"award-info":[{"award-number":["U23A6011"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007129","name":"Natural Science Foundation of Shandong Province","doi-asserted-by":"publisher","award":["ZR2023MH003"],"award-info":[{"award-number":["ZR2023MH003"]}],"id":[{"id":"10.13039\/501100007129","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007129","name":"Natural Science Foundation of Shandong Province","doi-asserted-by":"publisher","award":["ZR2023QH424"],"award-info":[{"award-number":["ZR2023QH424"]}],"id":[{"id":"10.13039\/501100007129","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007129","name":"Natural Science Foundation of Shandong Province","doi-asserted-by":"publisher","award":["ZR2022QH056"],"award-info":[{"award-number":["ZR2022QH056"]}],"id":[{"id":"10.13039\/501100007129","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["jlr.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Lipid Research"],"published-print":{"date-parts":[[2026,10]]},"DOI":"10.1016\/j.jlr.2026.101135","type":"journal-article","created":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T23:58:21Z","timestamp":1788307101000},"page":"101135","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Lipoprotein(a) and the C-reactive protein-triglyceride-glucose index in relation to coronary lesion burden in patients with acute coronary syndrome"],"prefix":"10.1016","volume":"67","author":[{"given":"Pinpeng","family":"Xie","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhiyuan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chaosheng","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wanting","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weichun","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chungang","family":"Zhai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Qiao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0350-1383","authenticated-orcid":false,"given":"Wenqiang","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jlr.2026.101135_bib1","doi-asserted-by":"crossref","DOI":"10.1161\/CIR.0000000000001123","article-title":"Heart disease and stroke Statistics-2023 update: a report from the American Heart Association","volume":"147","author":"Tsao","year":"2023","journal-title":"Circulation"},{"key":"10.1016\/j.jlr.2026.101135_bib2","first-page":"2258","article-title":"Updated focused review of hematological, inflammatory, and lipid biomarkers in acute coronary syndrome","volume":"21","author":"Budzianowski","year":"2025","journal-title":"Arch. Med. Sci."},{"key":"10.1016\/j.jlr.2026.101135_bib3","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.atherosclerosis.2019.05.012","article-title":"A guide for Gensini score calculation","volume":"287","author":"Rampidis","year":"2019","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.jlr.2026.101135_bib4","doi-asserted-by":"crossref","first-page":"2347","DOI":"10.1016\/j.jcin.2023.07.043","article-title":"Complete percutaneous coronary revascularization in acute coronary syndromes with multivessel coronary disease: a systematic review","volume":"16","author":"Faro","year":"2023","journal-title":"JACC Cardiovasc. Interv."},{"key":"10.1016\/j.jlr.2026.101135_bib5","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1186\/s12933-024-02304-0","article-title":"Aggravating effect of abnormal low-density protein cholesterol level on coronary atherosclerotic plaque in type 2 diabetes mellitus patients assessed by coronary computed tomography angiography","volume":"23","author":"Jiang","year":"2024","journal-title":"Cardiovasc. Diabetol."},{"key":"10.1016\/j.jlr.2026.101135_bib6","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1016\/S2213-8587(17)30088-8","article-title":"Apolipoprotein(a) isoform size, lipoprotein(a) concentration, and coronary artery disease: a mendelian randomisation analysis","volume":"5","author":"Saleheen","year":"2017","journal-title":"Lancet Diabetes Endocrinol."},{"key":"10.1016\/j.jlr.2026.101135_bib7","doi-asserted-by":"crossref","first-page":"3925","DOI":"10.1093\/eurheartj\/ehac361","article-title":"Lipoprotein(a) in atherosclerotic cardiovascular disease and aortic stenosis: a European Atherosclerosis Society consensus statement","volume":"43","author":"Kronenberg","year":"2022","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.jlr.2026.101135_bib8","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1016\/j.jacc.2016.11.042","article-title":"A Test in context: lipoprotein(a): diagnosis, prognosis, controversies, and emerging therapies","volume":"69","author":"Tsimikas","year":"2017","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.jlr.2026.101135_bib9","doi-asserted-by":"crossref","first-page":"1551","DOI":"10.1002\/clc.23718","article-title":"Elevated serum lipoprotein(a) is significantly associated with angiographic progression of coronary artery disease","volume":"44","author":"Shui","year":"2021","journal-title":"Clin. Cardiol."},{"key":"10.1016\/j.jlr.2026.101135_bib10","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/j.jacc.2021.10.044","article-title":"Association of Lipoprotein(a) with atherosclerotic plaque progression","volume":"79","author":"Kaiser","year":"2022","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.jlr.2026.101135_bib11","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1186\/s12872-022-02870-9","article-title":"Neutrophils to high-density lipoprotein cholesterol ratio as a new prognostic marker in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention: a retrospective study","volume":"22","author":"Chen","year":"2022","journal-title":"BMC Cardiovasc. Disord."},{"key":"10.1016\/j.jlr.2026.101135_bib12","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1016\/j.hlc.2016.02.023","article-title":"Monocyte to HDL cholesterol ratio predicts coronary artery disease severity and future major cardiovascular adverse events in acute coronary syndrome","volume":"25","author":"Cetin","year":"2016","journal-title":"Heart Lung Circ."},{"key":"10.1016\/j.jlr.2026.101135_bib13","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1186\/s12944-024-02055-7","article-title":"The predictive value of the hs-CRP\/HDL-C ratio, an inflammation-lipid composite marker, for cardiovascular disease in middle-aged and elderly people: evidence from a large national cohort study","volume":"23","author":"Gao","year":"2024","journal-title":"Lipids Health Dis."},{"key":"10.1016\/j.jlr.2026.101135_bib14","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0335916","article-title":"The association between the C-reactive protein-triglyceride-glucose index and cardiovascular diseases: a cohort study using data from the China Health and Retirement Longitudinal Study 2011-2020","volume":"20","author":"Xu","year":"2025","journal-title":"PLoS One"},{"key":"10.1016\/j.jlr.2026.101135_bib15","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1186\/s12933-018-0762-4","article-title":"Association between insulin resistance and the development of cardiovascular disease","volume":"17","author":"Ormazabal","year":"2018","journal-title":"Cardiovasc. Diabetol."},{"key":"10.1016\/j.jlr.2026.101135_bib16","doi-asserted-by":"crossref","first-page":"3347","DOI":"10.1210\/jc.2010-0288","article-title":"The product of triglycerides and glucose, a simple measure of insulin sensitivity. Comparison with the euglycemic-hyperinsulinemic clamp","volume":"95","author":"Guerrero-Romero","year":"2010","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.jlr.2026.101135_bib17","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1056\/NEJMoa1707914","article-title":"Antiinflammatory therapy with canakinumab for atherosclerotic disease","volume":"377","author":"Ridker","year":"2017","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.jlr.2026.101135_bib18","article-title":"Association of C reactive protein triglyceride glucose index with mortality in coronary heart disease and type 2 diabetes from NHANES data","volume":"15","author":"Tang","year":"2025","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jlr.2026.101135_bib19","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1186\/s12933-025-02960-w","article-title":"The relationship between C-reactive protein-triglyceride-glucose index and cardiovascular disease: insights from the China health and retirement longitudinal study (CHARLS)","volume":"24","author":"Zhang","year":"2025","journal-title":"Cardiovasc. Diabetol."},{"key":"10.1016\/j.jlr.2026.101135_bib20","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1016\/j.jacc.2021.07.016","article-title":"High-Sensitivity C-Reactive protein modifies the cardiovascular risk of Lipoprotein(a): Multi-Ethnic Study of atherosclerosis","volume":"78","author":"Zhang","year":"2021","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.jlr.2026.101135_bib21","doi-asserted-by":"crossref","first-page":"2000","DOI":"10.1016\/j.jacc.2025.08.101","article-title":"Association of Lipoprotein(a) and Interleukin-6 with cardiovascular risk: MESA and UK biobank","volume":"86","author":"Bhatia","year":"2025","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.jlr.2026.101135_bib22","doi-asserted-by":"crossref","DOI":"10.1016\/j.jacadv.2024.101409","article-title":"Association of Lipoprotein(a) with major adverse cardiovascular events across hs-CRP: a systematic review and meta-analysis","volume":"3","author":"Alebna","year":"2024","journal-title":"JACC Adv."},{"key":"10.1016\/j.jlr.2026.101135_bib23","doi-asserted-by":"crossref","first-page":"1156","DOI":"10.1136\/heartjnl-2017-311198","article-title":"Machine learning in cardiovascular medicine: are we there yet?","volume":"104","author":"Shameer","year":"2018","journal-title":"Heart"},{"key":"10.1016\/j.jlr.2026.101135_bib24","doi-asserted-by":"crossref","DOI":"10.1093\/bib\/bbad236","article-title":"Explainable AI for bioinformatics: methods, tools and applications","volume":"24","author":"Karim","year":"2023","journal-title":"Brief. Bioinform."},{"key":"10.1016\/j.jlr.2026.101135_bib25","doi-asserted-by":"crossref","first-page":"3720","DOI":"10.1093\/eurheartj\/ehad191","article-title":"2023 ESC Guidelines for the management of acute coronary syndromes","volume":"44","author":"Byrne","year":"2023","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.jlr.2026.101135_bib26","doi-asserted-by":"crossref","first-page":"868","DOI":"10.1038\/nature01323","article-title":"Inflammation in atherosclerosis","volume":"420","author":"Libby","year":"2002","journal-title":"Nature"},{"key":"10.1016\/j.jlr.2026.101135_bib27","doi-asserted-by":"crossref","first-page":"e308","DOI":"10.1016\/j.jacl.2024.03.001","article-title":"A focused update to the 2019 NLA scientific statement on use of lipoprotein(a) in clinical practice","volume":"18","author":"Koschinsky","year":"2024","journal-title":"J. Clin. Lipidol."},{"key":"10.1016\/j.jlr.2026.101135_bib28","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1016\/j.jacl.2019.04.010","article-title":"Use of lipoprotein(a) in clinical practice: a biomarker whose time has come. A scientific statement from the National Lipid Association","volume":"13","author":"Wilson","year":"2019","journal-title":"J. Clin. Lipidol."},{"key":"10.1016\/j.jlr.2026.101135_bib29","doi-asserted-by":"crossref","first-page":"C74","DOI":"10.1093\/eurheartjsupp\/suad010","article-title":"Acute coronary syndromes and multivessel coronary artery disease","volume":"25","author":"Zimbardo","year":"2023","journal-title":"Eur. Heart J. Suppl."},{"key":"10.1016\/j.jlr.2026.101135_bib30","doi-asserted-by":"crossref","first-page":"4359","DOI":"10.1093\/eurheartj\/ehaf190","article-title":"2025 focused update of the 2019 ESC\/EAS Guidelines for the management of dyslipidaemias","volume":"46","author":"Mach","year":"2025","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.jlr.2026.101135_bib31","doi-asserted-by":"crossref","first-page":"3227","DOI":"10.1093\/eurheartj\/ehab484","article-title":"2021 ESC Guidelines on cardiovascular disease prevention in clinical practice","volume":"42","author":"Visseren","year":"2021","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.jlr.2026.101135_bib32","article-title":"SCAI expert consensus statement on the management of calcified coronary lesions","volume":"3","author":"Riley","year":"2024","journal-title":"J. Soc. Cardiovasc. Angiogr Interv."},{"key":"10.1016\/j.jlr.2026.101135_bib33","article-title":"2021 ACC\/AHA\/SCAI Guideline for coronary artery revascularization: a report of the American college of Cardiology\/American Heart Association Joint Committee on clinical practice Guidelines","volume":"145","author":"Lawton","year":"2021","journal-title":"Circulation"},{"key":"10.1016\/j.jlr.2026.101135_bib34","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1253\/circj.CJ-12-0205","article-title":"Defining the coronary slow flow phenomenon","volume":"76","author":"Beltrame","year":"2012","journal-title":"Circ. J."},{"key":"10.1016\/j.jlr.2026.101135_bib35","article-title":"SCAI expert consensus statement on management of In-Stent restenosis and stent thrombosis","volume":"2","author":"Klein","year":"2023","journal-title":"J. Soc. Cardiovasc. Angiogr Interv."},{"key":"10.1016\/j.jlr.2026.101135_bib36","doi-asserted-by":"crossref","first-page":"1","DOI":"10.18637\/jss.v033.i01","article-title":"Regularization paths for generalized Linear models via coordinate descent","volume":"33","author":"Friedman","year":"2010","journal-title":"J. Stat. Softw."},{"key":"10.1016\/j.jlr.2026.101135_bib37","doi-asserted-by":"crossref","first-page":"2087","DOI":"10.1056\/NEJMoa2405182","article-title":"Inflammation, cholesterol, Lipoprotein(a), and 30-Year cardiovascular outcomes in women","volume":"391","author":"Ridker","year":"2024","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.jlr.2026.101135_bib38","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1161\/CIRCULATIONAHA.124.069556","article-title":"Independence of lipoprotein(a) and low-density lipoprotein cholesterol-mediated cardiovascular risk: a participant-level meta-analysis","volume":"151","author":"Bhatia","year":"2024","journal-title":"Circulation"},{"key":"10.1016\/j.jlr.2026.101135_bib39","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1161\/CIRCULATIONAHA.116.020838","article-title":"Oxidized phospholipids on lipoprotein(a) elicit arterial wall inflammation and an inflammatory monocyte response in humans","volume":"134","author":"van der Valk","year":"2016","journal-title":"Circulation"},{"key":"10.1016\/j.jlr.2026.101135_bib40","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1038\/s41569-018-0153-2","article-title":"Oxidized phospholipids as a unifying theory for lipoprotein(a) and cardiovascular disease","volume":"16","author":"Boffa","year":"2019","journal-title":"Nat. Rev. Cardiol."},{"key":"10.1016\/j.jlr.2026.101135_bib41","doi-asserted-by":"crossref","first-page":"1255","DOI":"10.1016\/S0140-6736(24)01308-4","article-title":"Lipoprotein(a) and cardiovascular disease","volume":"404","author":"Nordestgaard","year":"2024","journal-title":"Lancet"},{"key":"10.1016\/j.jlr.2026.101135_bib42","doi-asserted-by":"crossref","first-page":"1485","DOI":"10.1161\/ATVBAHA.124.319483","article-title":"Lipoprotein(a) in the year 2024: a look back and a look ahead","volume":"44","author":"Tsimikas","year":"2024","journal-title":"Arterioscler Thromb. Vasc. Biol."},{"key":"10.1016\/j.jlr.2026.101135_bib43","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1093\/eurjpc\/zwae007","article-title":"Impact of elevated lipoprotein(a) on coronary artery disease phenotype and severity","volume":"31","author":"Leistner","year":"2024","journal-title":"Eur. J. Prev. Cardiol."},{"key":"10.1016\/j.jlr.2026.101135_bib44","article-title":"Role of LipoprotEin(a) in CardiovascuLar diseases and premature acute coronary syndromes (RELACS study): impact of Lipoprotein(a) levels on the premature coronary event and the severity of coronary artery disease","volume":"35","author":"Cesaro","year":"2024","journal-title":"Nutr. Metab. Cardiovasc. Dis."},{"key":"10.1016\/j.jlr.2026.101135_bib45","doi-asserted-by":"crossref","DOI":"10.3389\/fcvm.2025.1669234","article-title":"Value of lipoprotein(a) in predicting severity of coronary artery stenosis in patients with chronic coronary artery disease: a cross-sectional study in Vietnam","volume":"12","author":"Phan","year":"2025","journal-title":"Front. Cardiovasc. Med."},{"key":"10.1016\/j.jlr.2026.101135_bib46","doi-asserted-by":"crossref","first-page":"1743","DOI":"10.1016\/j.jacc.2024.03.367","article-title":"Association of Lipoprotein(a) levels with myocardial infarction in patients with low-attenuation plaque","volume":"83","author":"Yu","year":"2024","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.jlr.2026.101135_bib47","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1186\/s13098-025-01882-7","article-title":"Association between different dimensions of the C-reactive protein-triglyceride-glucose index and future cardiovascular disease risk in individuals with cardiovascular-kidney-metabolic syndrome stages 0-3: a nationwide cohort study","volume":"17","author":"Chen","year":"2025","journal-title":"Diabetol. Metab. Syndr."},{"key":"10.1016\/j.jlr.2026.101135_bib48","doi-asserted-by":"crossref","DOI":"10.3389\/fcvm.2023.1213177","article-title":"Monocyte and macrophage foam cells in diabetes-accelerated atherosclerosis","volume":"10","author":"Cervantes","year":"2023","journal-title":"Front. Cardiovasc. Med."},{"key":"10.1016\/j.jlr.2026.101135_bib49","doi-asserted-by":"crossref","first-page":"1687","DOI":"10.1007\/s40200-024-01482-8","article-title":"Modification macrophage to foam cells in atherosclerosis disease: some factors stimulate or inhibit this process","volume":"23","author":"Saki","year":"2024","journal-title":"J. Diabetes Metab. Disord."},{"key":"10.1016\/j.jlr.2026.101135_bib50","doi-asserted-by":"crossref","first-page":"2057","DOI":"10.1161\/01.CIR.94.9.2057","article-title":"Fibrinolytic factors and the risk of myocardial infarction or sudden death in patients with angina pectoris. ECAT Study Group. European Concerted Action on Thrombosis and Disabilities","volume":"94","author":"Juhan-Vague","year":"1996","journal-title":"Circulation"},{"key":"10.1016\/j.jlr.2026.101135_bib51","doi-asserted-by":"crossref","first-page":"2518","DOI":"10.1056\/NEJMoa0902604","article-title":"Genetic variants associated with Lp(a) lipoprotein level and coronary disease","volume":"361","author":"Clarke","year":"2009","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.jlr.2026.101135_bib52","doi-asserted-by":"crossref","first-page":"2331","DOI":"10.1001\/jama.2009.801","article-title":"Genetically elevated lipoprotein(a) and increased risk of myocardial infarction","volume":"301","author":"Kamstrup","year":"2009","journal-title":"JAMA"},{"key":"10.1016\/j.jlr.2026.101135_bib53","doi-asserted-by":"crossref","first-page":"2262","DOI":"10.1093\/eurheartj\/ehaa171","article-title":"Potent lipoprotein(a) lowering following apolipoprotein(a) antisense treatment reduces the pro-inflammatory activation of circulating monocytes in patients with elevated lipoprotein(a)","volume":"41","author":"Stiekema","year":"2020","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.jlr.2026.101135_bib54","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1056\/NEJMoa1809798","article-title":"Low-Dose methotrexate for the prevention of atherosclerotic events","volume":"380","author":"Ridker","year":"2018","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.jlr.2026.101135_bib55","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1186\/s12933-025-02848-9","article-title":"C-reactive protein-triglyceride glucose index in evaluating cardiovascular disease and all-cause mortality incidence among individuals across stages 0-3 of cardiovascular-kidney-metabolic syndrome: a nationwide prospective cohort study","volume":"24","author":"Ou","year":"2025","journal-title":"Cardiovasc. Diabetol."},{"key":"10.1016\/j.jlr.2026.101135_bib56","doi-asserted-by":"crossref","first-page":"1855","DOI":"10.1056\/NEJMoa2211023","article-title":"Small interfering RNA to reduce Lipoprotein(a) in cardiovascular disease","volume":"387","author":"O'Donoghue","year":"2022","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.jlr.2026.101135_bib57","doi-asserted-by":"crossref","first-page":"1606","DOI":"10.1161\/CIR.0000000000001184","article-title":"Cardiovascular-kidney-metabolic health: a presidential advisory from the American Heart Association","volume":"148","author":"Ndumele","year":"2023","journal-title":"Circulation"}],"container-title":["Journal of Lipid Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022227526001653?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022227526001653?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T20:20:05Z","timestamp":1793305205000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022227526001653"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":57,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2026,10]]}},"alternative-id":["S0022227526001653"],"URL":"https:\/\/doi.org\/10.1016\/j.jlr.2026.101135","relation":{},"ISSN":["0022-2275"],"issn-type":[{"value":"0022-2275","type":"print"}],"subject":[],"published":{"date-parts":[[2026,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Lipoprotein(a) and the C-reactive protein-triglyceride-glucose index in relation to coronary lesion burden in patients with acute coronary syndrome","name":"articletitle","label":"Article Title"},{"value":"Journal of Lipid Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jlr.2026.101135","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Inc on behalf of American Society for Biochemistry and Molecular Biology.","name":"copyright","label":"Copyright"}],"article-number":"101135"}}