{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,6]],"date-time":"2026-04-06T22:38:09Z","timestamp":1775515089241,"version":"3.50.1"},"reference-count":91,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2017,4,1]],"date-time":"2017-04-01T00:00:00Z","timestamp":1491004800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"NIH-NHLBI K99\/R00","award":["HL107744"],"award-info":[{"award-number":["HL107744"]}]},{"name":"NIH-NHLBI K99\/R00","award":["HL128457"],"award-info":[{"award-number":["HL128457"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Molecular Biology"],"published-print":{"date-parts":[[2017,4]]},"DOI":"10.1016\/j.jmb.2017.02.012","type":"journal-article","created":{"date-parts":[[2017,2,24]],"date-time":"2017-02-24T07:31:45Z","timestamp":1487921505000},"page":"1045-1066","source":"Crossref","is-referenced-by-count":26,"title":["Cullin E3 Ligase Activity Is Required for Myoblast Differentiation"],"prefix":"10.1016","volume":"429","author":[{"given":"Jordan","family":"Blondelle","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paige","family":"Shapiro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea A.","family":"Domenighetti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9361-6602","authenticated-orcid":false,"given":"Stephan","family":"Lange","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jmb.2017.02.012_bb0005","doi-asserted-by":"crossref","first-page":"1645","DOI":"10.1002\/cphy.c130009","article-title":"Mechanisms modulating skeletal muscle phenotype","volume":"3","author":"Blaauw","year":"2013","journal-title":"Compr. Physiol."},{"key":"10.1016\/j.jmb.2017.02.012_bb0010","doi-asserted-by":"crossref","first-page":"2121","DOI":"10.1016\/j.biocel.2013.04.023","article-title":"Protein breakdown in muscle wasting: role of autophagy\u2013lysosome and ubiquitin-proteasome","volume":"45","author":"Sandri","year":"2013","journal-title":"Int. J. Biochem. Cell Biol."},{"key":"10.1016\/j.jmb.2017.02.012_bb0015","first-page":"245","article-title":"Cardiac cytoarchitecture: how to maintain a working heart\u2014waste disposal and recycling in cardiomyocytes","author":"Blondelle","year":"2015"},{"key":"10.1016\/j.jmb.2017.02.012_bb0020","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1038\/nature02263","article-title":"Protein degradation and protection against misfolded or damaged proteins","volume":"426","author":"Goldberg","year":"2003","journal-title":"Nature"},{"key":"10.1016\/j.jmb.2017.02.012_bb0025","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1242\/dmm.010389","article-title":"Cellular and molecular mechanisms of muscle atrophy","volume":"6","author":"Bonaldo","year":"2013","journal-title":"Dis. Model. Mech."},{"key":"10.1016\/j.jmb.2017.02.012_bb0030","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1186\/1747-1028-3-7","article-title":"Cullin\u2013RING ubiquitin ligases: global regulation and activation cycles","volume":"3","author":"Bosu","year":"2008","journal-title":"Cell Div."},{"key":"10.1016\/j.jmb.2017.02.012_bb0035","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1038\/nrm1547","article-title":"Function and regulation of cullin\u2013RING ubiquitin ligases","volume":"6","author":"Petroski","year":"2005","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.jmb.2017.02.012_bb0040","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1038\/cr.2013.44","article-title":"Genetically engineered mouse models for functional studies of SKP1-CUL1-F-box-protein (SCF) E3 ubiquitin ligases","volume":"23","author":"Zhou","year":"2013","journal-title":"Cell Res."},{"key":"10.1016\/j.jmb.2017.02.012_bb0045","doi-asserted-by":"crossref","first-page":"28,557","DOI":"10.1074\/jbc.272.45.28557","article-title":"Characterization of NEDD8, a developmentally down-regulated ubiquitin-like protein","volume":"272","author":"Kamitani","year":"1997","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.jmb.2017.02.012_bb0050","doi-asserted-by":"crossref","first-page":"1704","DOI":"10.1126\/science.1065874","article-title":"Identification of ubiquitin ligases required for skeletal muscle atrophy","volume":"294","author":"Bodine","year":"2001","journal-title":"Science"},{"key":"10.1016\/j.jmb.2017.02.012_bb0055","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/2044-5040-4-11","article-title":"Kelch proteins: emerging roles in skeletal muscle development and diseases","volume":"4","author":"Gupta","year":"2014","journal-title":"Skelet. Muscle"},{"key":"10.1016\/j.jmb.2017.02.012_bb0060","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1177\/1947601910382899","article-title":"Cullins and cancer","volume":"1","author":"Lee","year":"2010","journal-title":"Genes Cancer"},{"key":"10.1016\/j.jmb.2017.02.012_bb0065","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1016\/j.tibs.2009.07.002","article-title":"CRL4s: the CUL4-RING E3 ubiquitin ligases","volume":"34","author":"Jackson","year":"2009","journal-title":"Trends Biochem. Sci."},{"key":"10.1016\/j.jmb.2017.02.012_bb0070","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1038\/nature07884","article-title":"An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer","volume":"458","author":"Soucy","year":"2009","journal-title":"Nature"},{"key":"10.1016\/j.jmb.2017.02.012_bb0075","doi-asserted-by":"crossref","first-page":"2069","DOI":"10.1093\/emboj\/19.9.2069","article-title":"Targeted disruption of Skp2 results in accumulation of cyclin E and p27(Kip1), polyploidy and centrosome overduplication","volume":"19","author":"Nakayama","year":"2000","journal-title":"EMBO J."},{"key":"10.1016\/j.jmb.2017.02.012_bb0080","doi-asserted-by":"crossref","first-page":"2375","DOI":"10.1101\/gad.13.18.2375","article-title":"Cullin-3 targets cyclin E for ubiquitination and controls S phase in mammalian cells","volume":"13","author":"Singer","year":"1999","journal-title":"Genes Dev."},{"key":"10.1016\/j.jmb.2017.02.012_bb0085","doi-asserted-by":"crossref","first-page":"3215","DOI":"10.2174\/13816128113199990300","article-title":"Cullin\u2013RING ligases as attractive anti-cancer targets","volume":"19","author":"Zhao","year":"2013","journal-title":"Curr. Pharm. Des."},{"key":"10.1016\/j.jmb.2017.02.012_bb0090","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1158\/1078-0432.CCR-15-1237","article-title":"Phase I study of the novel investigational NEDD8-activating enzyme inhibitor Pevonedistat (MLN4924) in patients with relapsed\/refractory multiple myeloma or lymphoma","volume":"22","author":"Shah","year":"2016","journal-title":"Clin. Cancer Res."},{"key":"10.1016\/j.jmb.2017.02.012_bb0095","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1158\/1078-0432.CCR-15-1338","article-title":"Phase I study of the investigational NEDD8-activating enzyme inhibitor Pevonedistat (TAK-924\/MLN4924) in patients with advanced solid tumors","volume":"22","author":"Sarantopoulos","year":"2016","journal-title":"Clin. Cancer Res."},{"key":"10.1016\/j.jmb.2017.02.012_bb0100","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1038\/nrc3829","article-title":"Cancer cachexia: understanding the molecular basis","volume":"14","author":"Argiles","year":"2014","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.jmb.2017.02.012_bb0105","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1097\/00000441-193211000-00002","article-title":"The immediate causes of death in cancer","volume":"184","author":"Warren","year":"1932","journal-title":"Am. J. Med. Sci."},{"key":"10.1016\/j.jmb.2017.02.012_bb0110","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1016\/j.clnu.2007.03.011","article-title":"Pathophysiology of cancer cachexia: much more than host\u2013tumour interaction?","volume":"26","author":"Skipworth","year":"2007","journal-title":"Clin. Nutr."},{"key":"10.1016\/j.jmb.2017.02.012_bb0115","doi-asserted-by":"crossref","first-page":"4821","DOI":"10.1172\/JCI68523","article-title":"NF-kappaB-mediated Pax7 dysregulation in the muscle microenvironment promotes cancer cachexia","volume":"123","author":"He","year":"2013","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.jmb.2017.02.012_bb0120","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1016\/S1470-2045(08)70153-0","article-title":"Prevalence and clinical implications of sarcopenic obesity in patients with solid tumours of the respiratory and gastrointestinal tracts: a population-based study","volume":"9","author":"Prado","year":"2008","journal-title":"The Lancet Oncology"},{"key":"10.1016\/j.jmb.2017.02.012_bb0125","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/S1470-2045(10)70218-7","article-title":"Definition and classification of cancer cachexia: an international consensus","volume":"12","author":"Fearon","year":"2011","journal-title":"Lancet Oncol."},{"key":"10.1016\/j.jmb.2017.02.012_bb0130","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1104\/pp.111.176677","article-title":"MLN4924 is an efficient inhibitor of NEDD8 conjugation in plants","volume":"156","author":"Hakenjos","year":"2011","journal-title":"Plant Physiol."},{"key":"10.1016\/j.jmb.2017.02.012_bb0135","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1038\/270725a0","article-title":"Serial passaging and differentiation of myogenic cells isolated from dystrophic mouse muscle","volume":"270","author":"Yaffe","year":"1977","journal-title":"Nature"},{"key":"10.1016\/j.jmb.2017.02.012_bb0140","doi-asserted-by":"crossref","first-page":"e13039","DOI":"10.1371\/journal.pone.0013039","article-title":"Simple and high yielding method for preparing tissue specific extracellular matrix coatings for cell culture","volume":"5","author":"DeQuach","year":"2010","journal-title":"PLoS One"},{"key":"10.1016\/j.jmb.2017.02.012_bb0145","article-title":"Identification and validation of quantitative PCR reference genes suitable for normalizing expression in normal and dystrophic cell culture models of myogenesis","volume":"6","author":"Hildyard","year":"2014","journal-title":"PLoS Curr."},{"key":"10.1016\/j.jmb.2017.02.012_bb0150","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1242\/dev.109.1.139","article-title":"Fusion between myoblasts and adult muscle fibers promotes remodeling of fibers into myotubes in vitro","volume":"109","author":"Hinterberger","year":"1990","journal-title":"Development"},{"key":"10.1016\/j.jmb.2017.02.012_bb0155","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1016\/0092-8674(86)90707-5","article-title":"Developmental progression of myosin gene expression in cultured muscle cells","volume":"46","author":"Silberstein","year":"1986","journal-title":"Cell"},{"key":"10.1016\/j.jmb.2017.02.012_bb0160","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1242\/jeb.132.1.223","article-title":"Identification of agrin in electric organ extracts and localization of agrin-like molecules in muscle and central nervous system","volume":"132","author":"Smith","year":"1987","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.jmb.2017.02.012_bb0165","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1016\/j.ccr.2012.02.009","article-title":"Treatment-emergent mutations in NAEbeta confer resistance to the NEDD8-activating enzyme inhibitor MLN4924","volume":"21","author":"Milhollen","year":"2012","journal-title":"Cancer Cell"},{"key":"10.1016\/j.jmb.2017.02.012_bb0170","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1111\/bjh.13323","article-title":"Pevonedistat (MLN4924), a first-in-class NEDD8-activating enzyme inhibitor, in patients with acute myeloid leukaemia and myelodysplastic syndromes: a phase 1 study","volume":"169","author":"Swords","year":"2015","journal-title":"Br. J. Haematol."},{"key":"10.1016\/j.jmb.2017.02.012_bb0175","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1517\/14728222.2011.550877","article-title":"Targeting protein neddylation: a novel therapeutic strategy for the treatment of cancer","volume":"15","author":"Wang","year":"2011","journal-title":"Expert Opin. Ther. Targets"},{"key":"10.1016\/j.jmb.2017.02.012_bb0180","doi-asserted-by":"crossref","first-page":"1578","DOI":"10.1038\/cr.2011.90","article-title":"The methyl-CpG-binding protein CIBZ suppresses myogenic differentiation by directly inhibiting myogenin expression","volume":"21","author":"Oikawa","year":"2011","journal-title":"Cell Res."},{"key":"10.1016\/j.jmb.2017.02.012_bb0185","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1016\/S1097-2765(03)00341-1","article-title":"BTB\/POZ domain proteins are putative substrate adaptors for cullin 3 ubiquitin ligases","volume":"12","author":"Geyer","year":"2003","journal-title":"Mol. Cell"},{"key":"10.1016\/j.jmb.2017.02.012_bb0190","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1038\/nature01985","article-title":"BTB proteins are substrate-specific adaptors in an SCF-like modular ubiquitin ligase containing CUL-3","volume":"425","author":"Xu","year":"2003","journal-title":"Nature"},{"key":"10.1016\/j.jmb.2017.02.012_bb0195","doi-asserted-by":"crossref","first-page":"26,448","DOI":"10.1074\/jbc.M500373200","article-title":"Ubiquitin-proteasome-mediated degradation, intracellular localization, and protein synthesis of MyoD and Id1 during muscle differentiation","volume":"280","author":"Sun","year":"2005","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.jmb.2017.02.012_bb0200","doi-asserted-by":"crossref","first-page":"e1003398","DOI":"10.1371\/journal.pgen.1003398","article-title":"Dynamic circadian protein-protein interaction networks predict temporal organization of cellular functions","volume":"9","author":"Wallach","year":"2013","journal-title":"PLoS Genet."},{"key":"10.1016\/j.jmb.2017.02.012_bb0205","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1006\/bbrc.1999.0289","article-title":"IkappaBalpha ubiquitination is catalyzed by an SCF-like complex containing Skp1, cullin-1, and two F-box\/WD40-repeat proteins, betaTrCP1 and betaTrCP2","volume":"256","author":"Suzuki","year":"1999","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.jmb.2017.02.012_bb0210","doi-asserted-by":"crossref","first-page":"14,242","DOI":"10.1074\/jbc.M802257200","article-title":"Down-regulation of CIBZ, a novel substrate of caspase-3, induces apoptosis","volume":"283","author":"Oikawa","year":"2008","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.jmb.2017.02.012_bb0215","doi-asserted-by":"crossref","first-page":"52,643","DOI":"10.1074\/jbc.M409188200","article-title":"Sharp-1\/DEC2 inhibits skeletal muscle differentiation through repression of myogenic transcription factors","volume":"279","author":"Azmi","year":"2004","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.jmb.2017.02.012_bb0220","doi-asserted-by":"crossref","first-page":"1177","DOI":"10.1369\/jhc.6R6995.2006","article-title":"The skeletal muscle satellite cell: the stem cell that came in from the cold","volume":"54","author":"Zammit","year":"2006","journal-title":"J. Histochem. Cytochem."},{"key":"10.1016\/j.jmb.2017.02.012_bb0225","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.1369\/0022155411426780","article-title":"The skeletal muscle satellite cell: still young and fascinating at 50","volume":"59","author":"Yablonka-Reuveni","year":"2011","journal-title":"J. Histochem. Cytochem."},{"key":"10.1016\/j.jmb.2017.02.012_bb0230","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1083\/jcb.200701027","article-title":"Necdin mediates skeletal muscle regeneration by promoting myoblast survival and differentiation","volume":"179","author":"Deponti","year":"2007","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.jmb.2017.02.012_bb0235","doi-asserted-by":"crossref","first-page":"2623","DOI":"10.1091\/mbc.E12-01-0055","article-title":"UNC-89 (obscurin) binds to MEL-26, a BTB-domain protein, and affects the function of MEI-1 (katanin) in striated muscle of Caenorhabditis elegans","volume":"23","author":"Wilson","year":"2012","journal-title":"Mol. Biol. Cell"},{"key":"10.1016\/j.jmb.2017.02.012_bb0240","doi-asserted-by":"crossref","first-page":"2490","DOI":"10.1091\/mbc.E12-01-0052","article-title":"Obscurin and KCTD6 regulate cullin-dependent small ankyrin-1 (sAnk1.5) protein turnover","volume":"23","author":"Lange","year":"2012","journal-title":"Mol. Biol. Cell"},{"key":"10.1016\/j.jmb.2017.02.012_bb0245","doi-asserted-by":"crossref","first-page":"25,057","DOI":"10.1074\/jbc.M010378200","article-title":"Positive and negative regulation of myogenic differentiation of C2C12 cells by isoforms of the multiple homeodomain zinc finger transcription factor ATBF1","volume":"276","author":"Berry","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.jmb.2017.02.012_bb0250","doi-asserted-by":"crossref","first-page":"1658","DOI":"10.1038\/cdd.2016.56","article-title":"MicroRNA-17-92 regulates myoblast proliferation and differentiation by targeting the ENH1\/Id1 signaling axis","volume":"23","author":"Qiu","year":"2016","journal-title":"Cell Death Differ."},{"key":"10.1016\/j.jmb.2017.02.012_bb0255","doi-asserted-by":"crossref","first-page":"19,785","DOI":"10.1074\/jbc.272.32.19785","article-title":"Differential interactions of id proteins with basic-helix-loop-helix transcription factors","volume":"272","author":"Langlands","year":"1997","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.jmb.2017.02.012_bb0260","doi-asserted-by":"crossref","first-page":"23,498","DOI":"10.1074\/jbc.M110.206003","article-title":"Teashirt-3, a novel regulator of muscle differentiation, associates with BRG1-associated factor 57 (BAF57) to inhibit myogenin gene expression","volume":"286","author":"Faralli","year":"2011","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.jmb.2017.02.012_bb0265","doi-asserted-by":"crossref","first-page":"1249","DOI":"10.1074\/jbc.M109.046441","article-title":"The notch effector Hey1 associates with myogenic target genes to repress myogenesis","volume":"285","author":"Buas","year":"2010","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.jmb.2017.02.012_bb0270","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1186\/1471-2121-11-64","article-title":"HMGA1 down-regulation is crucial for chromatin composition and a gene expression profile permitting myogenic differentiation","volume":"11","author":"Brocher","year":"2010","journal-title":"BMC Cell Biol."},{"key":"10.1016\/j.jmb.2017.02.012_bb0275","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1016\/j.bbrc.2004.10.090","article-title":"Regulation of Rb gene expression by an MBD2-interacting zinc finger protein MIZF during myogenic differentiation","volume":"325","author":"Sekimata","year":"2004","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.jmb.2017.02.012_bb0280","doi-asserted-by":"crossref","first-page":"3765","DOI":"10.1091\/mbc.E14-04-0895","article-title":"The RNA-binding protein Staufen1 impairs myogenic differentiation via a c-myc-dependent mechanism","volume":"25","author":"Ravel-Chapuis","year":"2014","journal-title":"Mol. Biol. Cell"},{"key":"10.1016\/j.jmb.2017.02.012_bb0285","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/j.yexcr.2015.06.009","article-title":"JAZF1 promotes proliferation of C2C12 cells, but retards their myogenic differentiation through transcriptional repression of MEF2C and MRF4 implications for the role of Jazf1 variants in oncogenesis and type 2 diabetes","volume":"336","author":"Yuasa","year":"2015","journal-title":"Exp. Cell Res."},{"key":"10.1016\/j.jmb.2017.02.012_bb0290","doi-asserted-by":"crossref","first-page":"5329","DOI":"10.1242\/jcs.105239","article-title":"Foxk1 promotes cell proliferation and represses myogenic differentiation by regulating Foxo4 and Mef2","volume":"125","author":"Shi","year":"2012","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.jmb.2017.02.012_bb0295","doi-asserted-by":"crossref","first-page":"e0126808","DOI":"10.1371\/journal.pone.0126808","article-title":"Cullin 3 recognition is not a universal property among KCTD proteins","volume":"10","author":"Smaldone","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.jmb.2017.02.012_bb0300","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.jmb.2015.08.019","article-title":"Structural insights into KCTD protein assembly and Cullin3 recognition","volume":"428","author":"Ji","year":"2016","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.jmb.2017.02.012_bb0305","doi-asserted-by":"crossref","first-page":"1338","DOI":"10.1002\/ijc.22025","article-title":"Silencing of the UCHL1 gene in human colorectal and ovarian cancers","volume":"119","author":"Okochi-Takada","year":"2006","journal-title":"Int. J. Cancer"},{"key":"10.1016\/j.jmb.2017.02.012_bb0310","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1002\/pmic.200700261","article-title":"Proteome analysis of differentiating human myoblasts by dialysis-assisted two-dimensional gel electrophoresis (DAGE)","volume":"8","author":"Gonnet","year":"2008","journal-title":"Proteomics"},{"key":"10.1016\/j.jmb.2017.02.012_bb0315","doi-asserted-by":"crossref","first-page":"2986","DOI":"10.1096\/fj.12-204495","article-title":"Upregulation of proteasome activity in muscle RING finger 1-null mice following denervation","volume":"26","author":"Gomes","year":"2012","journal-title":"FASEB J."},{"key":"10.1016\/j.jmb.2017.02.012_bb0320","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1111\/nan.12168","article-title":"Increased levels of UCHL1 are a compensatory response to disrupted ubiquitin homeostasis in spinal muscular atrophy and do not represent a viable therapeutic target","volume":"40","author":"Powis","year":"2014","journal-title":"Neuropathol. Appl. Neurobiol."},{"key":"10.1016\/j.jmb.2017.02.012_bb0325","doi-asserted-by":"crossref","first-page":"1636","DOI":"10.1073\/pnas.0911516107","article-title":"Ubiquitin carboxyl-terminal hydrolase L1 is required for maintaining the structure and function of the neuromuscular junction","volume":"107","author":"Chen","year":"2010","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.jmb.2017.02.012_bb0330","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1242\/dev.068353","article-title":"Myoblast fusion: lessons from flies and mice","volume":"139","author":"Abmayr","year":"2012","journal-title":"Development"},{"key":"10.1016\/j.jmb.2017.02.012_bb0335","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.ydbio.2009.10.024","article-title":"Myoblast fusion: when it takes more to make one","volume":"341","author":"Rochlin","year":"2010","journal-title":"Dev. Biol."},{"key":"10.1016\/j.jmb.2017.02.012_bb0340","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1083\/jcb.132.4.657","article-title":"Myogenin expression, cell cycle withdrawal, and phenotypic differentiation are temporally separable events that precede cell fusion upon myogenesis","volume":"132","author":"Andres","year":"1996","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.jmb.2017.02.012_bb0345","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1038\/nature12343","article-title":"Myomaker is a membrane activator of myoblast fusion and muscle formation","volume":"499","author":"Millay","year":"2013","journal-title":"Nature"},{"key":"10.1016\/j.jmb.2017.02.012_bb0350","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1152\/physrev.00033.2014","article-title":"Mechanisms regulating neuromuscular junction development and function and causes of muscle wasting","volume":"95","author":"Tintignac","year":"2015","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.jmb.2017.02.012_bb0355","doi-asserted-by":"crossref","first-page":"12,564","DOI":"10.1073\/pnas.0914191107","article-title":"Loss of human Greatwall results in G2 arrest and multiple mitotic defects due to deregulation of the cyclin B-Cdc2\/PP2A balance","volume":"107","author":"Burgess","year":"2010","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.jmb.2017.02.012_bb0360","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1083\/jcb.99.2.615","article-title":"Components of torpedo electric organ and muscle that cause aggregation of acetylcholine receptors on cultured muscle cells","volume":"99","author":"Godfrey","year":"1984","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.jmb.2017.02.012_bb0365","doi-asserted-by":"crossref","first-page":"8195","DOI":"10.1074\/jbc.M808230200","article-title":"Control of rapsyn stability by the CUL-3-containing E3 ligase complex","volume":"284","author":"Nam","year":"2009","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.jmb.2017.02.012_bb0370","doi-asserted-by":"crossref","first-page":"2413","DOI":"10.1523\/JNEUROSCI.3226-13.2014","article-title":"Coronin 6 regulates acetylcholine receptor clustering through modulating receptor anchorage to actin cytoskeleton","volume":"34","author":"Chen","year":"2014","journal-title":"J. Neurosci."},{"key":"10.1016\/j.jmb.2017.02.012_bb0375","doi-asserted-by":"crossref","first-page":"3281","DOI":"10.1111\/febs.12309","article-title":"Endosomal trafficking of the receptor tyrosine kinase MuSK proceeds via clathrin-dependent pathways, Arf6 and actin","volume":"280","author":"Luiskandl","year":"2013","journal-title":"FEBS J."},{"key":"10.1016\/j.jmb.2017.02.012_bb0380","doi-asserted-by":"crossref","first-page":"e8478","DOI":"10.1371\/journal.pone.0008478","article-title":"The function of cortactin in the clustering of acetylcholine receptors at the vertebrate neuromuscular junction","volume":"4","author":"Madhavan","year":"2009","journal-title":"PLoS One"},{"key":"10.1016\/j.jmb.2017.02.012_bb0385","doi-asserted-by":"crossref","first-page":"1321","DOI":"10.1083\/jcb.150.6.1321","article-title":"The actin-driven movement and formation of acetylcholine receptor clusters","volume":"150","author":"Dai","year":"2000","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.jmb.2017.02.012_bb0390","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1083\/jcb.99.1.148","article-title":"Role of the cytoskeleton in the formation, stabilization, and removal of acetylcholine receptor clusters in cultured muscle cells","volume":"99","author":"Connolly","year":"1984","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.jmb.2017.02.012_bb0395","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1083\/jcb.90.3.789","article-title":"Cytoplasmic actin in postsynaptic structures at the neuromuscular junction","volume":"90","author":"Hall","year":"1981","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.jmb.2017.02.012_bb0400","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1007\/s11010-014-2309-7","article-title":"Cullin 4A and 4B ubiquitin ligases interact with gamma-tubulin and induce its polyubiquitination","volume":"401","author":"Thirunavukarasou","year":"2015","journal-title":"Mol. Cell. Biochem."},{"key":"10.1016\/j.jmb.2017.02.012_bb0405","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1016\/j.molcel.2014.03.047","article-title":"The 3M complex maintains microtubule and genome integrity","volume":"54","author":"Yan","year":"2014","journal-title":"Mol. Cell"},{"key":"10.1016\/j.jmb.2017.02.012_bb0410","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1016\/j.devcel.2010.10.013","article-title":"CRL2(LRR-1) targets a CDK inhibitor for cell cycle control in C. elegans and actin-based motility regulation in human cells","volume":"19","author":"Starostina","year":"2010","journal-title":"Dev. Cell"},{"key":"10.1016\/j.jmb.2017.02.012_bb0415","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1083\/jcb.200909017","article-title":"Drosophila Kelch functions with cullin-3 to organize the ring canal actin cytoskeleton","volume":"188","author":"Hudson","year":"2010","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.jmb.2017.02.012_bb0420","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1016\/j.molcel.2009.09.004","article-title":"Cullin mediates degradation of RhoA through evolutionarily conserved BTB adaptors to control actin cytoskeleton structure and cell movement","volume":"35","author":"Chen","year":"2009","journal-title":"Mol. Cell"},{"key":"10.1016\/j.jmb.2017.02.012_bb0425","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1038\/nrd4432","article-title":"SCF ubiquitin ligase-targeted therapies","volume":"13","author":"Skaar","year":"2014","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.jmb.2017.02.012_bb0430","first-page":"12","article-title":"Recent advances in SCF ubiquitin ligase complex: clinical implications","volume":"2016","author":"Zheng","year":"1866","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.jmb.2017.02.012_bb0435","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.ccr.2011.01.002","article-title":"NEDD8 pathways in cancer, sine quibus non","volume":"19","author":"Watson","year":"2011","journal-title":"Cancer Cell"},{"key":"10.1016\/j.jmb.2017.02.012_bb0440","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1093\/hmg\/ddt412","article-title":"Loss of FHL1 induces an age-dependent skeletal muscle myopathy associated with myofibrillar and intermyofibrillar disorganization in mice","volume":"23","author":"Domenighetti","year":"2014","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.jmb.2017.02.012_bb0445","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1111\/dmcn.12027","article-title":"Reduced satellite cell population may lead to contractures in children with cerebral palsy","volume":"55","author":"Smith","year":"2013","journal-title":"Dev. Med. Child Neurol."},{"key":"10.1016\/j.jmb.2017.02.012_bb0450","doi-asserted-by":"crossref","first-page":"12,120","DOI":"10.1038\/ncomms12120","article-title":"MLP and CARP are linked to chronic PKCalpha signalling in dilated cardiomyopathy","volume":"7","author":"Lange","year":"2016","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jmb.2017.02.012_bb0455","series-title":"ImageJ","author":"Rasband","year":"1997"}],"container-title":["Journal of Molecular Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022283617300888?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022283617300888?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,7,24]],"date-time":"2022-07-24T18:34:45Z","timestamp":1658687685000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022283617300888"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,4]]},"references-count":91,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2017,4]]}},"alternative-id":["S0022283617300888"],"URL":"https:\/\/doi.org\/10.1016\/j.jmb.2017.02.012","relation":{},"ISSN":["0022-2836"],"issn-type":[{"value":"0022-2836","type":"print"}],"subject":[],"published":{"date-parts":[[2017,4]]}}}