{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T06:15:47Z","timestamp":1784873747332,"version":"3.55.0"},"reference-count":66,"publisher":"Elsevier BV","issue":"24","license":[{"start":{"date-parts":[[2019,12,1]],"date-time":"2019-12-01T00:00:00Z","timestamp":1575158400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,12,1]],"date-time":"2019-12-01T00:00:00Z","timestamp":1575158400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100000057","name":"National Institute of General Medical Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000057","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Molecular Biology"],"published-print":{"date-parts":[[2019,12]]},"DOI":"10.1016\/j.jmb.2019.09.014","type":"journal-article","created":{"date-parts":[[2019,10,16]],"date-time":"2019-10-16T19:47:45Z","timestamp":1571255265000},"page":"5019-5031","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"title":["The Role of RNA in HIV-1 Vif-Mediated Degradation of APOBEC3H"],"prefix":"10.1016","volume":"431","author":[{"given":"Jiayi","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jordan T.","family":"Becker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ke","family":"Shi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kate V.","family":"Lauer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel J.","family":"Salamango","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideki","family":"Aihara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadine M.","family":"Shaban","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reuben S.","family":"Harris","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jmb.2019.09.014_bib1","doi-asserted-by":"crossref","first-page":"1220","DOI":"10.1016\/j.jmb.2013.10.033","article-title":"Multiple APOBEC3 restriction factors for HIV-1 and one Vif to rule them all","volume":"426","author":"Desimmie","year":"2014","journal-title":"J.\u00a0Mol. Biol."},{"key":"10.1016\/j.jmb.2019.09.014_bib2","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.virol.2015.03.012","article-title":"APOBECs and virus restriction","volume":"479","author":"Harris","year":"2015","journal-title":"Virology"},{"key":"10.1016\/j.jmb.2019.09.014_bib3","doi-asserted-by":"crossref","DOI":"10.1186\/s12977-017-0355-4","article-title":"A\u00a0conflict of interest: the evolutionary arms race between mammalian APOBEC3 and lentiviral Vif","volume":"14","author":"Nakano","year":"2017","journal-title":"Retrovirology"},{"key":"10.1016\/j.jmb.2019.09.014_bib4","doi-asserted-by":"crossref","first-page":"2009","DOI":"10.1016\/j.cub.2003.10.034","article-title":"The Vif protein of HIV triggers degradation of the human antiretroviral DNA deaminase APOBEC3G","volume":"13","author":"Conticello","year":"2003","journal-title":"Curr. Biol."},{"key":"10.1016\/j.jmb.2019.09.014_bib5","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/S0092-8674(03)00515-4","article-title":"Species-specific exclusion of APOBEC3G from HIV-1 virions by Vif","volume":"114","author":"Mariani","year":"2003","journal-title":"Cell"},{"key":"10.1016\/j.jmb.2019.09.014_bib6","doi-asserted-by":"crossref","first-page":"1398","DOI":"10.1038\/nm946","article-title":"HIV-1 Vif protein binds the editing enzyme APOBEC3G and induces its degradation","volume":"9","author":"Marin","year":"2003","journal-title":"Nat. Med."},{"key":"10.1016\/j.jmb.2019.09.014_bib7","doi-asserted-by":"crossref","first-page":"1404","DOI":"10.1038\/nm945","article-title":"The antiretroviral enzyme APOBEC3G is degraded by the proteasome in response to HIV-1 Vif","volume":"9","author":"Sheehy","year":"2003","journal-title":"Nat. Med."},{"key":"10.1016\/j.jmb.2019.09.014_bib8","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1016\/S1097-2765(03)00353-8","article-title":"HIV-1 Vif blocks the antiviral activity of APOBEC3G by impairing both its translation and intracellular stability","volume":"12","author":"Stopak","year":"2003","journal-title":"Mol. Cell"},{"key":"10.1016\/j.jmb.2019.09.014_bib9","doi-asserted-by":"crossref","first-page":"1056","DOI":"10.1126\/science.1089591","article-title":"Induction of APOBEC3G ubiquitination and degradation by an HIV-1 Vif-Cul5-SCF complex","volume":"302","author":"Yu","year":"2003","journal-title":"Science"},{"key":"10.1016\/j.jmb.2019.09.014_bib10","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1038\/nature10693","article-title":"Vif hijacks CBF-beta to degrade APOBEC3G and promote HIV-1 infection","volume":"481","author":"J\u00e4ger","year":"2011","journal-title":"Nature"},{"key":"10.1016\/j.jmb.2019.09.014_bib11","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1038\/nature10718","article-title":"T-cell differentiation factor CBF-beta regulates HIV-1 Vif-mediated evasion of host restriction","volume":"481","author":"Zhang","year":"2011","journal-title":"Nature"},{"key":"10.1016\/j.jmb.2019.09.014_bib12","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1128\/JVI.06082-11","article-title":"The activity spectrum of Vif from multiple HIV-1 subtypes against APOBEC3G, APOBEC3F, and APOBEC3H","volume":"86","author":"Binka","year":"2012","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.jmb.2019.09.014_bib13","doi-asserted-by":"crossref","first-page":"e1004761","DOI":"10.1371\/journal.pgen.1004761","article-title":"Natural polymorphisms in human APOBEC3H and HIV-1 Vif combine in primary T lymphocytes to affect viral G-to-A mutation levels and infectivity","volume":"10","author":"Refsland","year":"2014","journal-title":"PLoS Genet."},{"key":"10.1016\/j.jmb.2019.09.014_bib14","doi-asserted-by":"crossref","first-page":"1262","DOI":"10.1016\/j.jmb.2017.03.019","article-title":"Mapping region of human restriction factor APOBEC3H critical for interaction with HIV-1 Vif","volume":"429","author":"Nakashima","year":"2017","journal-title":"J.\u00a0Mol. Biol."},{"key":"10.1016\/j.jmb.2019.09.014_bib15","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1128\/JVI.01665-08","article-title":"Polymorphisms and splice variants influence the antiretroviral activity of human APOBEC3H","volume":"83","author":"Harari","year":"2009","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.jmb.2019.09.014_bib16","doi-asserted-by":"crossref","first-page":"1902","DOI":"10.1128\/JVI.01509-09","article-title":"A\u00a0single amino acid difference in human APOBEC3H variants determines HIV-1 Vif sensitivity","volume":"84","author":"Zhen","year":"2010","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.jmb.2019.09.014_bib17","doi-asserted-by":"crossref","first-page":"8197","DOI":"10.1128\/JVI.00624-11","article-title":"Polymorphism in human APOBEC3H affects a phenotype dominant for subcellular localization and antiviral activity","volume":"85","author":"Li","year":"2011","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.jmb.2019.09.014_bib18","doi-asserted-by":"crossref","first-page":"3142","DOI":"10.1128\/JVI.02049-10","article-title":"Analysis of human APOBEC3H haplotypes and anti-human immunodeficiency virus type 1 activity","volume":"85","author":"Wang","year":"2011","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.jmb.2019.09.014_bib19","doi-asserted-by":"crossref","first-page":"e02289","DOI":"10.1128\/JVI.02289-16","article-title":"The structural interface between HIV-1 Vif and human APOBEC3H","volume":"91","author":"Ooms","year":"2017","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.jmb.2019.09.014_bib20","doi-asserted-by":"crossref","first-page":"29105","DOI":"10.1074\/jbc.M601901200","article-title":"The anti-HIV-1 editing enzyme APOBEC3G binds HIV-1 RNA and messenger RNAs that shuttle between polysomes and stress granules","volume":"281","author":"Kozak","year":"2006","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.jmb.2019.09.014_bib21","doi-asserted-by":"crossref","first-page":"2165","DOI":"10.1128\/JVI.02287-06","article-title":"Antiviral protein APOBEC3G localizes to ribonucleoprotein complexes found in P bodies and stress granules","volume":"81","author":"Gallois-Montbrun","year":"2007","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.jmb.2019.09.014_bib22","doi-asserted-by":"crossref","first-page":"11047","DOI":"10.1128\/JVI.02070-13","article-title":"Mov10 and APOBEC3G localization to processing bodies is not required for virion incorporation and antiviral activity","volume":"87","author":"Izumi","year":"2013","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.jmb.2019.09.014_bib23","doi-asserted-by":"crossref","first-page":"11712","DOI":"10.1128\/JVI.00595-12","article-title":"HIV-1 replication and APOBEC3 antiviral activity are not regulated by P bodies","volume":"86","author":"Phalora","year":"2012","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.jmb.2019.09.014_bib24","doi-asserted-by":"crossref","first-page":"e00356","DOI":"10.1128\/MCB.00356-18","article-title":"APOBEC3H subcellular localization determinants define zipcode for targeting HIV-1 for restriction","volume":"38","author":"Salamango","year":"2018","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.jmb.2019.09.014_bib25","doi-asserted-by":"crossref","first-page":"9591","DOI":"10.1128\/JVI.02471-07","article-title":"Two regions within the amino-terminal half of APOBEC3G cooperate to determine cytoplasmic localization","volume":"82","author":"Stenglein","year":"2008","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.jmb.2019.09.014_bib26","doi-asserted-by":"crossref","first-page":"e41","DOI":"10.1371\/journal.ppat.0020041","article-title":"Human retroviral host restriction factors APOBEC3G and APOBEC3F localize to mRNA processing bodies","volume":"2","author":"Wichroski","year":"2006","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.jmb.2019.09.014_bib27","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.molcel.2017.12.010","article-title":"The antiviral and cancer genomic DNA deaminase APOBEC3H is regulated by an RNA-mediated dimerization mechanism","volume":"69","author":"Shaban","year":"2018","journal-title":"Mol. Cell"},{"key":"10.1016\/j.jmb.2019.09.014_bib28","doi-asserted-by":"crossref","first-page":"129","DOI":"10.3389\/fcimb.2019.00129","article-title":"Structural determinants of the APOBEC3G N-terminal domain for HIV-1 RNA association","volume":"9","author":"Fukuda","year":"2019","journal-title":"Front Cell Infect Microbiol."},{"key":"10.1016\/j.jmb.2019.09.014_bib29","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1038\/nsmb.3033","article-title":"Structure of the Vif-binding domain of the antiviral enzyme APOBEC3G","volume":"22","author":"Kouno","year":"2015","journal-title":"Nat. Struct. Mol. Biol."},{"key":"10.1016\/j.jmb.2019.09.014_bib30","doi-asserted-by":"crossref","first-page":"e1004609","DOI":"10.1371\/journal.ppat.1004609","article-title":"Promiscuous RNA binding ensures effective encapsidation of APOBEC3 proteins by HIV-1","volume":"11","author":"Apolonia","year":"2015","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.jmb.2019.09.014_bib31","doi-asserted-by":"crossref","first-page":"1228","DOI":"10.1261\/rna.964708","article-title":"Single-stranded RNA facilitates nucleocapsid: APOBEC3G complex formation","volume":"14","author":"Bogerd","year":"2008","journal-title":"RNA"},{"key":"10.1016\/j.jmb.2019.09.014_bib32","doi-asserted-by":"crossref","first-page":"33177","DOI":"10.1074\/jbc.M402062200","article-title":"The interaction between HIV-1 Gag and APOBEC3G","volume":"279","author":"Cen","year":"2004","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.jmb.2019.09.014_bib33","doi-asserted-by":"crossref","first-page":"3807","DOI":"10.1128\/JVI.02795-06","article-title":"Identification of amino acid residues in APOBEC3G required for regulation by human immunodeficiency virus type 1 Vif and virion encapsidation","volume":"81","author":"Huthoff","year":"2007","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.jmb.2019.09.014_bib34","doi-asserted-by":"crossref","first-page":"5870","DOI":"10.1128\/JVI.79.9.5870-5874.2005","article-title":"Viral RNA is required for the association of APOBEC3G with human immunodeficiency virus type 1 nucleoprotein complexes","volume":"79","author":"Khan","year":"2005","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.jmb.2019.09.014_bib35","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.virol.2004.08.006","article-title":"Specific packaging of APOBEC3G into HIV-1 virions is mediated by the nucleocapsid domain of the gag polyprotein precursor","volume":"328","author":"Schafer","year":"2004","journal-title":"Virology"},{"key":"10.1016\/j.jmb.2019.09.014_bib36","doi-asserted-by":"crossref","first-page":"35822","DOI":"10.1074\/jbc.M405761200","article-title":"Human apolipoprotein B mRNA-editing enzyme-catalytic polypeptide-like 3G (APOBEC3G) is incorporated into HIV-1 virions through interactions with viral and nonviral RNAs","volume":"279","author":"Svarovskaia","year":"2004","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.jmb.2019.09.014_bib37","doi-asserted-by":"crossref","first-page":"13112","DOI":"10.1128\/JVI.00892-07","article-title":"7SL RNA mediates virion packaging of the antiviral cytidine deaminase APOBEC3G","volume":"81","author":"Wang","year":"2007","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.jmb.2019.09.014_bib38","doi-asserted-by":"crossref","first-page":"1098","DOI":"10.1016\/j.jmb.2007.11.017","article-title":"Interaction with 7SL RNA but not with HIV-1 genomic RNA or P bodies is required for APOBEC3F virion packaging","volume":"375","author":"Wang","year":"2008","journal-title":"J.\u00a0Mol. Biol."},{"key":"10.1016\/j.jmb.2019.09.014_bib39","doi-asserted-by":"crossref","first-page":"e1005833","DOI":"10.1371\/journal.ppat.1005833","article-title":"The RNA binding specificity of human APOBEC3 proteins resembles that of HIV-1 nucleocapsid","volume":"12","author":"York","year":"2016","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.jmb.2019.09.014_bib40","doi-asserted-by":"crossref","first-page":"12058","DOI":"10.1128\/JVI.78.21.12058-12061.2004","article-title":"APOBEC3G incorporation into human immunodeficiency virus type 1 particles","volume":"78","author":"Zennou","year":"2004","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.jmb.2019.09.014_bib41","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.virol.2015.04.019","article-title":"RNA-binding residues in the N-terminus of APOBEC3G influence its DNA sequence specificity and retrovirus restriction efficiency","volume":"483","author":"B\u00e9langer","year":"2015","journal-title":"Virology"},{"key":"10.1016\/j.jmb.2019.09.014_bib42","doi-asserted-by":"crossref","first-page":"e1000231","DOI":"10.1371\/journal.ppat.1000231","article-title":"APOBEC3G inhibits elongation of HIV-1 reverse transcripts","volume":"4","author":"Bishop","year":"2008","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.jmb.2019.09.014_bib43","doi-asserted-by":"crossref","first-page":"1508","DOI":"10.1128\/JVI.02587-12","article-title":"Suppression of HIV-1 infection by APOBEC3 proteins in primary human CD4(+) T cells is associated with inhibition of processive reverse transcription as well as excessive cytidine deamination","volume":"87","author":"Gillick","year":"2013","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.jmb.2019.09.014_bib44","doi-asserted-by":"crossref","first-page":"7096","DOI":"10.1093\/nar\/gkm750","article-title":"Deaminase-independent inhibition of HIV-1 reverse transcription by APOBEC3G","volume":"35","author":"Iwatani","year":"2007","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.jmb.2019.09.014_bib45","doi-asserted-by":"crossref","first-page":"5881","DOI":"10.1128\/JVI.00062-14","article-title":"Quantification of deaminase activity-dependent and -independent restriction of HIV-1 replication mediated by APOBEC3F and APOBEC3G through experimental-mathematical investigation","volume":"88","author":"Kobayashi","year":"2014","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.jmb.2019.09.014_bib46","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1038\/s41467-017-00501-y","article-title":"Dimerization regulates both deaminase-dependent and deaminase-independent HIV-1 restriction by APOBEC3G","volume":"8","author":"Morse","year":"2017","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jmb.2019.09.014_bib47","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/j.cub.2004.12.068","article-title":"Antiviral function of APOBEC3G can be dissociated from cytidine deaminase activity","volume":"15","author":"Newman","year":"2005","journal-title":"Curr. Biol."},{"key":"10.1016\/j.jmb.2019.09.014_bib48","doi-asserted-by":"crossref","first-page":"7961","DOI":"10.1128\/JVI.00754-10","article-title":"The localization of APOBEC3H variants in HIV-1 virions determines their antiviral activity","volume":"84","author":"Ooms","year":"2010","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.jmb.2019.09.014_bib49","doi-asserted-by":"crossref","first-page":"10368","DOI":"10.1093\/nar\/gky676","article-title":"Structural basis of chimpanzee APOBEC3H dimerization stabilized by double-stranded RNA","volume":"46","author":"Matsuoka","year":"2018","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.jmb.2019.09.014_bib50","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1038\/s41467-017-01309-6","article-title":"APOBEC3H structure reveals an unusual mechanism of interaction with duplex RNA","volume":"8","author":"Bohn","year":"2017","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jmb.2019.09.014_bib51","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/j.chom.2013.09.006","article-title":"HIV-1 Vif adaptation to human APOBEC3H haplotypes","volume":"14","author":"Ooms","year":"2013","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.jmb.2019.09.014_bib52","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1128\/JVI.01344-09","article-title":"The range of human APOBEC3H sensitivity to lentiviral Vif proteins","volume":"84","author":"Li","year":"2010","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.jmb.2019.09.014_bib53","doi-asserted-by":"crossref","first-page":"12918","DOI":"10.1038\/ncomms12918","article-title":"The DNA cytosine deaminase APOBEC3H haplotype I likely contributes to breast and lung cancer mutagenesis","volume":"7","author":"Starrett","year":"2016","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jmb.2019.09.014_bib54","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1146\/annurev-biophys-051013-022846","article-title":"Split green fluorescent proteins: scope, limitations, and outlook","volume":"48","author":"Romei","year":"2019","journal-title":"Annu. Rev. Biophys."},{"key":"10.1016\/j.jmb.2019.09.014_bib55","doi-asserted-by":"crossref","first-page":"14013","DOI":"10.1038\/s41598-017-14459-w","article-title":"Split GFP technologies to structurally characterize and quantify functional biomolecular interactions of FTD-related proteins","volume":"7","author":"Foglieni","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jmb.2019.09.014_bib56","doi-asserted-by":"crossref","first-page":"17415","DOI":"10.1038\/s41598-017-17694-3","article-title":"Conformational switch regulates the DNA cytosine deaminase activity of human APOBEC3B","volume":"7","author":"Shi","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jmb.2019.09.014_bib57","doi-asserted-by":"crossref","first-page":"1296","DOI":"10.1016\/j.jmb.2013.12.014","article-title":"APOBEC3 multimerization correlates with HIV-1 packaging and restriction activity in living cells","volume":"426","author":"Li","year":"2014","journal-title":"J.\u00a0Mol. Biol."},{"key":"10.1016\/j.jmb.2019.09.014_bib58","doi-asserted-by":"crossref","first-page":"1890","DOI":"10.1038\/ncomms2883","article-title":"NMR structure of human restriction factor APOBEC3A reveals substrate binding and enzyme specificity","volume":"4","author":"Byeon","year":"2013","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jmb.2019.09.014_bib59","doi-asserted-by":"crossref","first-page":"15024","DOI":"10.1038\/ncomms15024","article-title":"Crystal structure of APOBEC3A bound to single-stranded DNA reveals structural basis for cytidine deamination and specificity","volume":"8","author":"Kouno","year":"2017","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jmb.2019.09.014_bib60","doi-asserted-by":"crossref","first-page":"e57744","DOI":"10.1371\/journal.pone.0057744","article-title":"The resistance of human APOBEC3H to HIV-1 NL4-3 molecular clone is determined by a single amino acid in Vif","volume":"8","author":"Ooms","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.jmb.2019.09.014_bib61","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1080\/15384101.2014.1000212","article-title":"Evolutionarily conserved pressure for the existence of distinct G2\/M cell cycle arrest and A3H inactivation functions in HIV-1 Vif","volume":"14","author":"Zhao","year":"2015","journal-title":"Cell Cycle"},{"key":"10.1016\/j.jmb.2019.09.014_bib62","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/s12977-014-0130-8","article-title":"Sequence and structural determinants of human APOBEC3H deaminase and anti-HIV-1 activities","volume":"12","author":"Mitra","year":"2015","journal-title":"Retrovirology"},{"key":"10.1016\/j.jmb.2019.09.014_bib63","doi-asserted-by":"crossref","first-page":"11046","DOI":"10.1038\/ncomms11046","article-title":"Versatile protein tagging in cells with split fluorescent protein","volume":"7","author":"Kamiyama","year":"2016","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jmb.2019.09.014_bib64","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1016\/j.cub.2008.04.073","article-title":"Evolution of HIV-1 isolates that use a novel Vif-independent mechanism to resist restriction by human APOBEC3G","volume":"18","author":"Hach\u00e9","year":"2008","journal-title":"Curr. Biol."},{"key":"10.1016\/j.jmb.2019.09.014_bib65","doi-asserted-by":"crossref","DOI":"10.1128\/JVI.02315-16","article-title":"Subcellular localization of HIV-1 gag-pol mRNAs regulates sites of virion assembly","volume":"91","author":"Becker","year":"2017","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.jmb.2019.09.014_bib66","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1038\/nmeth.2019","article-title":"Fiji: an open-source platform for biological-image analysis","volume":"9","author":"Schindelin","year":"2012","journal-title":"Nat. Methods"}],"container-title":["Journal of Molecular Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022283619305698?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022283619305698?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,19]],"date-time":"2025-09-19T21:29:39Z","timestamp":1758317379000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022283619305698"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12]]},"references-count":66,"journal-issue":{"issue":"24","published-print":{"date-parts":[[2019,12]]}},"alternative-id":["S0022283619305698"],"URL":"https:\/\/doi.org\/10.1016\/j.jmb.2019.09.014","relation":{},"ISSN":["0022-2836"],"issn-type":[{"value":"0022-2836","type":"print"}],"subject":[],"published":{"date-parts":[[2019,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The Role of RNA in HIV-1 Vif-Mediated Degradation of APOBEC3H","name":"articletitle","label":"Article Title"},{"value":"Journal of Molecular Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jmb.2019.09.014","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}