{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T01:58:44Z","timestamp":1792375124301,"version":"4.4.0"},"reference-count":59,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,8,1]],"date-time":"2018-08-01T00:00:00Z","timestamp":1533081600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,8,1]],"date-time":"2018-08-01T00:00:00Z","timestamp":1533081600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100005057","name":"National Tsing Hua University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005057","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["MOST105-2221-E-007-012-MY4"],"award-info":[{"award-number":["MOST105-2221-E-007-012-MY4"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["MOST103-2221-E-007-034-MY3"],"award-info":[{"award-number":["MOST103-2221-E-007-034-MY3"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the Mechanical Behavior of Biomedical Materials"],"published-print":{"date-parts":[[2018,8]]},"DOI":"10.1016\/j.jmbbm.2018.05.004","type":"journal-article","created":{"date-parts":[[2018,5,3]],"date-time":"2018-05-03T17:22:34Z","timestamp":1525368154000},"page":"54-63","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"special_numbering":"C","title":["Zebrafish as a model to study bone maturation: Nanoscale structural and mechanical characterization of age-related changes in the zebrafish vertebral column"],"prefix":"10.1016","volume":"84","author":[{"given":"Zhuo","family":"Chang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Po-Yu","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6022-0107","authenticated-orcid":false,"given":"Yung-Jen","family":"Chuang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Riaz","family":"Akhtar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jmbbm.2018.05.004_bib1","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1007\/BF00425881","article-title":"Energy-dispersive X-ray microanalysis of the bone mineral content in human trabecular bone: a comparison with ICPES and neutron activation analysis","volume":"55","author":"\u00c5kesson","year":"1994","journal-title":"Calcif. Tissue Int."},{"key":"10.1016\/j.jmbbm.2018.05.004_bib2","doi-asserted-by":"crossref","first-page":"1012","DOI":"10.1359\/jbmr.2003.18.6.1012","article-title":"Aging of microstructural compartments in human compact bone","volume":"18","author":"Akkus","year":"2003","journal-title":"J. Bone Miner. Res."},{"key":"10.1016\/j.jmbbm.2018.05.004_bib3","series-title":"The Human Odyssey: Navigating the Twelve Stages of Life","author":"Armstrong","year":"2007"},{"key":"10.1016\/j.jmbbm.2018.05.004_bib4","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1016\/j.ajhg.2012.02.026","article-title":"Attenuated BMP1 function compromises osteogenesis, leading to bone fragility in humans and zebrafish","volume":"90","author":"Asharani","year":"2012","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.jmbbm.2018.05.004_bib5","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1152\/physiolgenomics.2000.2.2.49","article-title":"Realizing the potential of zebrafish as a model for human disease","volume":"2","author":"Barut","year":"2000","journal-title":"Physiol. Genom."},{"key":"10.1016\/j.jmbbm.2018.05.004_bib6","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1111\/j.2517-6161.1995.tb02031.x","article-title":"Controlling the false discovery rate: a practical and powerful approach to multiple testing","author":"Benjamini","year":"1995","journal-title":"J. R. Stat. Soc. Ser. B (Methodol.)"},{"key":"10.1016\/j.jmbbm.2018.05.004_bib7","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1007\/s10741-016-9579-y","article-title":"Zebrafish models of cardiovascular disease","volume":"21","author":"Bournele","year":"2016","journal-title":"Heart Fail. Rev."},{"key":"10.1016\/j.jmbbm.2018.05.004_bib8","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1387\/ijdb.082615sb","article-title":"Zebrafish development and regeneration: new tools for biomedical research","volume":"53","author":"Brittijn","year":"2009","journal-title":"Int. J. Dev. Biol."},{"key":"10.1016\/j.jmbbm.2018.05.004_bib9","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1557\/jmr.2004.19.1.249","article-title":"Nanoindentation of bone: comparison of specimens tested in liquid and embedded in polymethylmethacrylate","volume":"19","author":"Bushby","year":"2004","journal-title":"J. Mater. Res."},{"key":"10.1016\/j.jmbbm.2018.05.004_bib10","doi-asserted-by":"crossref","DOI":"10.1101\/pdb.prot073411","article-title":"Manual hematoxylin and eosin staining of mouse tissue sections","volume":"2014","author":"Cardiff","year":"2014","journal-title":"Cold Spring Harb. Protoc."},{"key":"10.1016\/j.jmbbm.2018.05.004_bib11","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1007\/BF00296342","article-title":"An electron probe X-ray microanalytical study of bone mineral in osteogenesis imperfecta","volume":"56","author":"Cassella","year":"1995","journal-title":"Calcif. Tissue Int."},{"key":"10.1016\/j.jmbbm.2018.05.004_bib12","doi-asserted-by":"crossref","first-page":"1550074","DOI":"10.1142\/S0219519415500748","article-title":"Nanoindentation and ash content study of age dependent changes in porcine cortical bone","volume":"15","author":"Chittenden","year":"2015","journal-title":"J. Mech. Med. Biol."},{"key":"10.1016\/j.jmbbm.2018.05.004_bib13","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.mser.2007.04.001","article-title":"Self-assembly of mineralized collagen composites","volume":"57","author":"Cui","year":"2007","journal-title":"Mater. Sci. Eng.: R: Rep."},{"key":"10.1016\/j.jmbbm.2018.05.004_bib14","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1159\/000213580","article-title":"Age determination and longevity in fishes","volume":"40","author":"Das","year":"1994","journal-title":"Gerontology"},{"key":"10.1016\/j.jmbbm.2018.05.004_bib15","doi-asserted-by":"crossref","first-page":"1236","DOI":"10.1093\/gerona\/glt092","article-title":"Epidemiology of fracture risk with advancing age","volume":"68","author":"Ensrud","year":"2013","journal-title":"J. Gerontol. Ser. A: Biomed. Sci. Med. Sci."},{"key":"10.1016\/j.jmbbm.2018.05.004_bib16","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1359\/jbmr.2006.21.2.307","article-title":"Cortical and trabecular load sharing in the human vertebral body","volume":"21","author":"Eswaran","year":"2006","journal-title":"J. Bone Miner. Res."},{"key":"10.1016\/j.jmbbm.2018.05.004_bib17","doi-asserted-by":"crossref","first-page":"e34072","DOI":"10.1371\/journal.pone.0034072","article-title":"Swim-training changes the spatio-temporal dynamics of skeletogenesis in zebrafish larvae (Danio rerio)","volume":"7","author":"Fiaz","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.jmbbm.2018.05.004_bib18","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1016\/j.msec.2005.06.063","article-title":"Microstructural characteristics and nanomechanical properties across the thickness of the wild-type zebrafish skeletal bone","volume":"26","author":"Ge","year":"2006","journal-title":"Mater. Sci. Eng.: C"},{"key":"10.1016\/j.jmbbm.2018.05.004_bib19","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1016\/j.exger.2003.10.022","article-title":"Comparative aspects of zebrafish (Danio rerio) as a model for aging research","volume":"38","author":"Gerhard","year":"2003","journal-title":"Exp. Gerontol."},{"key":"10.1016\/j.jmbbm.2018.05.004_bib20","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.arr.2007.02.007","article-title":"Small laboratory fish as models for aging research","volume":"6","author":"Gerhard","year":"2007","journal-title":"Ageing Res. Rev."},{"key":"10.1016\/j.jmbbm.2018.05.004_bib21","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1016\/S0531-5565(02)00088-8","article-title":"Life spans and senescent phenotypes in two strains of Zebrafish (Danio rerio)","volume":"37","author":"Gerhard","year":"2002","journal-title":"Exp. Gerontol."},{"key":"10.1016\/j.jmbbm.2018.05.004_bib22","doi-asserted-by":"crossref","DOI":"10.1002\/jbmr.3231","article-title":"Immune suppressive and bone inhibitory effects of prednisolone in growing and regenerating zebrafish tissues","author":"Geurtzen","year":"2017","journal-title":"J. Bone Miner. Res."},{"key":"10.1016\/j.jmbbm.2018.05.004_bib23","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.exger.2013.11.013","article-title":"Zebrafish (Danio rerio) as a model for the study of aging and exercise: physical ability and trainability decrease with age","volume":"50","author":"Gilbert","year":"2014","journal-title":"Exp. Gerontol."},{"key":"10.1016\/j.jmbbm.2018.05.004_bib24","doi-asserted-by":"crossref","first-page":"531","DOI":"10.3233\/CBM-2011-0183","article-title":"Issues in collecting, processing and storing human tissues and associated information to support biomedical research","volume":"9","author":"Grizzle","year":"2011","journal-title":"Cancer Biomark."},{"key":"10.1016\/j.jmbbm.2018.05.004_bib25","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1016\/S0531-5565(03)00108-6","article-title":"The zebrafish as a vertebrate model of functional aging and very gradual senescence","volume":"38","author":"Kishi","year":"2003","journal-title":"Exp. Gerontol."},{"key":"10.1016\/j.jmbbm.2018.05.004_bib26","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1016\/j.devcel.2011.04.014","article-title":"Bone regenerates via dedifferentiation of osteoblasts in the zebrafish fin","volume":"20","author":"Knopf","year":"2011","journal-title":"Dev. Cell"},{"key":"10.1016\/j.jmbbm.2018.05.004_bib27","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1007\/s10867-011-9247-3","article-title":"Ca\/P concentration ratio at different sites of normal and osteoporotic rabbit bones evaluated by Auger and energy dispersive X-ray spectroscopy","volume":"38","author":"Kourkoumelis","year":"2012","journal-title":"J. Biol. Phys."},{"key":"10.1016\/j.jmbbm.2018.05.004_bib28","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1100\/tsw.2010.43","article-title":"Spectroscopic assessment of normal cortical bone: differences in relation to bone site and sex","volume":"10","author":"Kourkoumelis","year":"2010","journal-title":"Sci. World J."},{"key":"10.1016\/j.jmbbm.2018.05.004_bib29","first-page":"29","article-title":"Fish: a suitable system to model human bone disorders and discover drugs with osteogenic or osteotoxic activities","volume":"13","author":"Laiz\u00e9","year":"2014","journal-title":"Drug Discov. Today: Dis. Models"},{"key":"10.1016\/j.jmbbm.2018.05.004_bib30","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1359\/jbmr.2000.15.1.13","article-title":"Trabecular bone microarchitecture, bone mineral density, and vertebral fractures in male osteoporosis","volume":"15","author":"Legrand","year":"2000","journal-title":"J. Bone Miner. Res."},{"key":"10.1016\/j.jmbbm.2018.05.004_bib31","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1038\/nrg2091","article-title":"Animal models of human disease: zebrafish swim into view","volume":"8","author":"Lieschke","year":"2007","journal-title":"Nat. Rev. Genet."},{"key":"10.1016\/j.jmbbm.2018.05.004_bib32","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1007\/s002230001192","article-title":"Effect of fixation, soft-tissues, and scan projection on bone mineral measurements with dual energy X-ray absorptiometry (DXA)","volume":"68","author":"Lochm\u00fcller","year":"2001","journal-title":"Calcif. Tissue Int."},{"key":"10.1016\/j.jmbbm.2018.05.004_bib33","article-title":"A bone to pick with zebrafish","volume":"2","author":"Mackay","year":"2013","journal-title":"Bone Rep."},{"key":"10.1016\/j.jmbbm.2018.05.004_bib34","doi-asserted-by":"crossref","first-page":"12748","DOI":"10.1073\/pnas.0803354105","article-title":"Amorphous calcium phosphate is a major component of the forming fin bones of zebrafish: indications for an amorphous precursor phase","volume":"105","author":"Mahamid","year":"2008","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.jmbbm.2018.05.004_bib35","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/j.bone.2015.11.018","article-title":"Mechanical properties of cortical bone and their relationships with age, gender, composition and microindentation properties in the elderly","volume":"93","author":"Mirzaali","year":"2016","journal-title":"Bone"},{"key":"10.1016\/j.jmbbm.2018.05.004_bib36","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1093\/ilar.53.2.161","article-title":"Zebrafish breeding in the laboratory environment","volume":"53","author":"Nasiadka","year":"2012","journal-title":"ILAR J."},{"key":"10.1016\/j.jmbbm.2018.05.004_bib37","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1093\/toxsci\/55.1.171","article-title":"Modeling normal aging bone loss, with consideration of bone loss in osteoporosis","volume":"55","author":"O'Flaherty","year":"2000","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.jmbbm.2018.05.004_bib38","doi-asserted-by":"crossref","first-page":"942","DOI":"10.1016\/j.bone.2011.12.026","article-title":"Age-specific profiles of tissue-level composition and mechanical properties in murine cortical bone","volume":"50","author":"Raghavan","year":"2012","journal-title":"Bone"},{"key":"10.1016\/j.jmbbm.2018.05.004_bib39","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/S0021-9290(01)00199-3","article-title":"Microstructural elasticity and regional heterogeneity in human femoral bone of various ages examined by nano-indentation","volume":"35","author":"Rho","year":"2002","journal-title":"J. Biomech."},{"key":"10.1016\/j.jmbbm.2018.05.004_bib40","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1007\/PL00005829","article-title":"Abnormal mineral composition of osteogenesis imperfecta bone as determined by electron probe X-ray microanalysis on conventional and cryosections","volume":"65","author":"Sarathchandra","year":"1999","journal-title":"Calcif. Tissue Int."},{"key":"10.1016\/j.jmbbm.2018.05.004_bib41","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1002\/sca.4950020304","article-title":"The role of the buffer in the fixation of biological specimens for transmission and scanning electron microscopy","volume":"2","author":"Schiff","year":"1979","journal-title":"Scanning"},{"key":"10.1016\/j.jmbbm.2018.05.004_bib42","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1016\/S8756-3282(03)00060-7","article-title":"Co-dependence of calcium and phosphorus for growth and bone development under conditions of varying deficiency","volume":"32","author":"Shapiro","year":"2003","journal-title":"Bone"},{"key":"10.1016\/j.jmbbm.2018.05.004_bib43","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1146\/annurev.genom.3.031402.131506","article-title":"From zebrafish to human: modular medical models","volume":"3","author":"Shin","year":"2002","journal-title":"Annu. Rev. Genom. Hum. Genet."},{"key":"10.1016\/j.jmbbm.2018.05.004_bib44","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1111\/j.1439-0426.2010.01409.x","article-title":"Zebrafish as a unique model system in bone research: the power of genetics and in vivo imaging","volume":"26","author":"Spoorendonk","year":"2010","journal-title":"J. Appl. Ichthyol."},{"key":"10.1016\/j.jmbbm.2018.05.004_bib45","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1016\/j.diff.2012.05.005","article-title":"Zebrafish models in cardiac development and congenital heart birth defects","volume":"84","author":"Tu","year":"2012","journal-title":"Differentiation"},{"key":"10.1016\/j.jmbbm.2018.05.004_bib46","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1385\/BTER:93:1-3:63","article-title":"Calcium, phosphorus, calcium-phosphorus ratio in rib bone of healthy humans","volume":"93","author":"Tzaphlidou","year":"2003","journal-title":"Biol. Trace Elem. Res."},{"key":"10.1016\/j.jmbbm.2018.05.004_bib47","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.1111\/bcp.12408","article-title":"Zebrafish as model organisms for studying drug\u2010induced liver injury","volume":"78","author":"Vliegenthart","year":"2014","journal-title":"Br. J. Clin. Pharmacol."},{"key":"10.1016\/j.jmbbm.2018.05.004_bib48","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1007\/BF02441170","article-title":"Age-related changes in the density and tensile strength of human femoral cortical bone","volume":"27","author":"Wall","year":"1979","journal-title":"Calcif. Tissue Int."},{"key":"10.1016\/j.jmbbm.2018.05.004_bib49","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1016\/S0022-0248(03)01543-4","article-title":"Alterations in mineral properties of zebrafish skeletal bone induced by liliput dtc232 gene mutation","volume":"258","author":"Wang","year":"2003","journal-title":"J. Cryst. Growth"},{"key":"10.1016\/j.jmbbm.2018.05.004_bib50","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/j.jsb.2003.10.028","article-title":"Hierarchical structural comparisons of bones from wild-type and liliput dtc232 gene-mutated zebrafish","volume":"145","author":"Wang","year":"2004","journal-title":"J. Struct. Biol."},{"key":"10.1016\/j.jmbbm.2018.05.004_bib51","doi-asserted-by":"crossref","first-page":"4557","DOI":"10.1016\/S0142-9612(02)00201-6","article-title":"Variation of nanomechanical properties of bone by gene mutation in the zebrafish","volume":"23","author":"Wang","year":"2002","journal-title":"Biomaterials"},{"key":"10.1016\/j.jmbbm.2018.05.004_bib52","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1111\/joa.12480","article-title":"Functional bone histology of zebrafish reveals two types of endochondral ossification, different types of osteoblast clusters and a new bone type","volume":"229","author":"Weigele","year":"2016","journal-title":"J. Anat."},{"key":"10.1016\/j.jmbbm.2018.05.004_bib53","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1111\/joa.12480","article-title":"Functional bone histology of zebrafish reveals two types of endochondral ossification, different types of osteoblast clusters and a new bone type","volume":"229","author":"Weigele","year":"2016","journal-title":"J. Anat."},{"key":"10.1016\/j.jmbbm.2018.05.004_bib54","series-title":"The Zebrafish Book: A Guide for the Laboratory Use of Zebrafish (Danio rerio)","author":"Westerfield","year":"1995"},{"key":"10.1016\/j.jmbbm.2018.05.004_bib55","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1002\/jmor.1065","article-title":"Features of mono\u2010and multinucleated bone resorbing cells of the zebrafish Danio rerio and their contribution to skeletal development, remodeling, and growth","volume":"250","author":"Witten","year":"2001","journal-title":"J. Morphol."},{"key":"10.1016\/j.jmbbm.2018.05.004_bib56","doi-asserted-by":"crossref","first-page":"S-24","DOI":"10.1089\/zeb.2015.1208","article-title":"A sketch of the Taiwan zebrafish core facility","volume":"13","author":"You","year":"2016","journal-title":"Zebrafish"},{"key":"10.1016\/j.jmbbm.2018.05.004_bib57","doi-asserted-by":"crossref","first-page":"125703","DOI":"10.1088\/0957-0233\/22\/12\/125703","article-title":"The use of the PeakForce\u2122 quantitative nanomechanical mapping AFM-based method for high-resolution Young's modulus measurement of polymers","volume":"22","author":"Young","year":"2011","journal-title":"Meas. Sci. Technol."},{"key":"10.1016\/j.jmbbm.2018.05.004_bib58","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1016\/S0969-8043(02)00066-0","article-title":"Determination of calcium, phosphorus, and the calcium\/phosphorus ratio in cortical bone from the human femoral neck by neutron activation analysis","volume":"56","author":"Zaichick","year":"2002","journal-title":"Appl. Radiat. Isot."},{"key":"10.1016\/j.jmbbm.2018.05.004_bib59","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1016\/S8756-3282(02)00676-2","article-title":"Mechanical properties of skeletal bone in gene-mutated st\u00f6psel dtl28d and wild-type zebrafish (Danio rerio) measured by atomic force microscopy-based nanoindentation","volume":"30","author":"Zhang","year":"2002","journal-title":"Bone"}],"container-title":["Journal of the Mechanical Behavior of Biomedical Materials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1751616118301401?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1751616118301401?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T22:24:25Z","timestamp":1761690265000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1751616118301401"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,8]]},"references-count":59,"alternative-id":["S1751616118301401"],"URL":"https:\/\/doi.org\/10.1016\/j.jmbbm.2018.05.004","relation":{},"ISSN":["1751-6161"],"issn-type":[{"value":"1751-6161","type":"print"}],"subject":[],"published":{"date-parts":[[2018,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Zebrafish as a model to study bone maturation: Nanoscale structural and mechanical characterization of age-related changes in the zebrafish vertebral column","name":"articletitle","label":"Article Title"},{"value":"Journal of the Mechanical Behavior of Biomedical Materials","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jmbbm.2018.05.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}