{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T02:22:43Z","timestamp":1781144563947,"version":"3.54.1"},"reference-count":70,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100000852","name":"Henry Smith Charity","doi-asserted-by":"publisher","award":["20141464"],"award-info":[{"award-number":["20141464"]}],"id":[{"id":"10.13039\/501100000852","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the Mechanical Behavior of Biomedical Materials"],"published-print":{"date-parts":[[2021,6]]},"DOI":"10.1016\/j.jmbbm.2021.104458","type":"journal-article","created":{"date-parts":[[2021,3,18]],"date-time":"2021-03-18T16:22:15Z","timestamp":1616084535000},"page":"104458","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"special_numbering":"C","title":["Micro-mechanical damage of needle puncture on bovine annulus fibrosus fibrils studied using polarization-resolved Second Harmonic Generation(P-SHG) microscopy"],"prefix":"10.1016","volume":"118","author":[{"given":"J.-Y.","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.C.","family":"Mansfield","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Brasselet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Vergari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7403-185X","authenticated-orcid":false,"given":"J.R.","family":"Meakin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.P.","family":"Winlove","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jmbbm.2021.104458_bib1","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.cplett.2005.06.018","article-title":"Local orientational distribution of molecular monolayers probed by nonlinear microscopy","volume":"411","author":"Anceau","year":"2005","journal-title":"Chem. Phys. Lett."},{"key":"10.1016\/j.jmbbm.2021.104458_bib2","article-title":"Polarization dependence of aligned collagen tissues imaged with second harmonic generation microscopy","volume":"20","author":"\u00c1vila","year":"2015","journal-title":"J. Biomecial Optics"},{"key":"10.1016\/j.jmbbm.2021.104458_bib3","doi-asserted-by":"crossref","DOI":"10.1117\/1.JBO.17.8.080506","article-title":"Microscopic structural study of collagen aging in isolated fibrils using polarized second harmonic generation","volume":"17","author":"A\u00eft-Belkacem","year":"2012","journal-title":"J. Biomed. Opt."},{"key":"10.1016\/j.jmbbm.2021.104458_bib4","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1097\/00007632-199007000-00015","article-title":"Lumbar discography followed by computed tomography","volume":"15","author":"Bernard","year":"1990","journal-title":"Spine"},{"key":"10.1016\/j.jmbbm.2021.104458_bib5","doi-asserted-by":"crossref","first-page":"1339","DOI":"10.1089\/ten.tea.2009.0442","article-title":"Self-assembly of aligned tissue-engineered annulus fibrosus and intervertebral disc composite via collagen gel contraction","volume":"16","author":"Bowles","year":"2010","journal-title":"Tissue Eng."},{"key":"10.1016\/j.jmbbm.2021.104458_bib6","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1364\/AOP.3.000205","article-title":"Polarization-resolved nonlinear microscopy: application to structural molecular and biological imaging","volume":"3","author":"Brasselet","year":"2011","journal-title":"Adv. Opt Photon"},{"key":"10.1016\/j.jmbbm.2021.104458_bib7","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1007\/s00586-016-4560-y","article-title":"Staying connected: structural integration at the intervertebral disc-vertebra interface of human lumbar spines","volume":"26","author":"Brown","year":"2016","journal-title":"Eur. Spine J."},{"key":"10.1016\/j.jmbbm.2021.104458_bib8","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1046\/j.1469-7580.2002.00080.x","article-title":"Regional variations in the cellular matrix of the annulus fibrosus of the intervertebral disc","volume":"201","author":"Bruehlmann","year":"2002","journal-title":"J. Anat."},{"key":"10.1016\/j.jmbbm.2021.104458_bib9","doi-asserted-by":"crossref","DOI":"10.5772\/63493","article-title":"Second harmonic generation microscopy: a tool for quantitative analysis of tissues","author":"Bueno","year":"2016","journal-title":"Microsc. Anal.: Chap 5"},{"key":"10.1016\/j.jmbbm.2021.104458_bib10","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1021\/ac60315a005","article-title":"Bi-Gaussian fitting of skewed peaks","volume":"44","author":"Buys","year":"1972","journal-title":"Anal. Chem."},{"key":"10.1016\/j.jmbbm.2021.104458_bib11","doi-asserted-by":"crossref","first-page":"3224","DOI":"10.1021\/ac1032325","article-title":"Second harmonic generation imaging microscopy: applications to diseases diagnostics","volume":"83","author":"Campagnola","year":"2011","journal-title":"Anal. Chem."},{"key":"10.1016\/j.jmbbm.2021.104458_bib12","doi-asserted-by":"crossref","first-page":"2115","DOI":"10.1097\/01.brs.0000231436.30262.dd","article-title":"A gold standard evaluation of the \u201cdiscogenic pain\u201d diagnosis as determined by provocative discography","volume":"31","author":"Carragee","year":"2006","journal-title":"Spine"},{"key":"10.1016\/j.jmbbm.2021.104458_bib13","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1038\/nprot.2012.009","article-title":"Second harmonic generation microscopy for quantitative analysis of collagen fibrillar structure","volume":"7","author":"Chen","year":"2012","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.jmbbm.2021.104458_bib14","doi-asserted-by":"crossref","first-page":"S119","DOI":"10.1097\/01.bsd.0000127823.54485.3f","article-title":"Nucleoplasty with or without intradiscal electrothermal therapy (IDET) as a treatment for lumbar herniated disc","volume":"18","author":"Cohen","year":"2005","journal-title":"Spinal Discard Tech"},{"key":"10.1016\/j.jmbbm.2021.104458_bib15","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1007\/978-1-59259-993-6_2","article-title":"Second-harmonic imaging of collagen","volume":"319","author":"Cox","year":"2006","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.jmbbm.2021.104458_bib16","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/j.spinee.2015.06.051","article-title":"Does provocative discography cause clinically important injury to the lumbar intervertebral disc? A 10-year matched cohort study","volume":"16","author":"Cuellar","year":"2016","journal-title":"Spine J."},{"key":"10.1016\/j.jmbbm.2021.104458_bib17","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1021\/jp9046837","article-title":"Measurement of the second-order hyperpolarizability of the collagen triple helix and determination of its physical origin","volume":"113","author":"Deniset-Besseau","year":"2009","journal-title":"J. Phys. Chem. B"},{"key":"10.1016\/j.jmbbm.2021.104458_bib18","series-title":"Intervertebral Disc Visualization by Combined Two-Photon Excitation Fluorescence and Second-Harmonic Generation Microscopy (Master Dissertation)","author":"Dittmar","year":"2008"},{"key":"10.1016\/j.jmbbm.2021.104458_bib19","doi-asserted-by":"crossref","DOI":"10.1103\/PhysRevA.85.043829","article-title":"Generic model of the molecular orientational distribution probed by polarization-resolved second-harmonic generation","volume":"85","author":"Duboisset","year":"2012","journal-title":"Phys. Rev."},{"key":"10.1016\/j.jmbbm.2021.104458_bib20","first-page":"671","article-title":"Low back pain","volume":"81","author":"Ehrlich","year":"2003","journal-title":"Bull. World Health Organ."},{"key":"10.1016\/j.jmbbm.2021.104458_bib23","first-page":"1","article-title":"Cells and biomaterials for intervertebral disc regeneration","volume":"5","author":"Grad","year":"2010","journal-title":"Synthesis lectures on tissue engineering"},{"key":"10.1016\/j.jmbbm.2021.104458_bib24","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1471-2474-1-1","article-title":"Human disc cells in monolayer vs 3D culture: cell shape, division and matrix formation","volume":"1","author":"Gruber","year":"2000","journal-title":"BMC Muscoskel. Disord."},{"key":"10.1016\/j.jmbbm.2021.104458_bib25","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1080\/10520290310001593793","article-title":"Cell shape and gene expression in human intervertebral disc cells: in vitro tissue engineering studies","volume":"78","author":"Gruber","year":"2003","journal-title":"Biotech. Histochem."},{"key":"10.1016\/j.jmbbm.2021.104458_bib26","doi-asserted-by":"crossref","first-page":"11S","DOI":"10.1016\/S1529-9430(02)00563-6","volume":"3","author":"Guyer","year":"2003","journal-title":"Spine J."},{"key":"10.1016\/j.jmbbm.2021.104458_bib27","doi-asserted-by":"crossref","first-page":"226","DOI":"10.22203\/eCM.v022a18","article-title":"Collagen fibrillogenesis in the development of the annulus fibrosus of the intervertebral disc","volume":"22","author":"Hayes","year":"2011","journal-title":"Eur. Cell. Mater."},{"key":"10.1016\/j.jmbbm.2021.104458_bib28","first-page":"351","article-title":"Collagen fibril diameters and elastic fibres in the annulus fibrosus of human fetal intervertebral disc","volume":"133","author":"Hickey","year":"1981","journal-title":"J. Anat."},{"issue":"3","key":"10.1016\/j.jmbbm.2021.104458_bib29","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1097\/00007632-198205000-00007","article-title":"Aging changes in the macromolecular organization of the intervertebral disc: an X-ray diffraction and electron microscopic study","volume":"7","author":"Hickey","year":"1982","journal-title":"Spine"},{"key":"10.1016\/j.jmbbm.2021.104458_bib30","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1016\/j.spinee.2012.03.006","article-title":"Does needle injection cause disc degeneration? News in the continuing debate regarding pathophysiology associated with intradiscal injections","volume":"12","author":"Iatridis","year":"2012","journal-title":"Spine J."},{"key":"10.1016\/j.jmbbm.2021.104458_bib31","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1016\/j.jbiomech.2003.12.026","article-title":"Mechanisms for mechanical damage in the intervertebral disc annulus fibrosus","volume":"37","author":"Iatridis","year":"2004","journal-title":"J. Biomech."},{"key":"10.1016\/j.jmbbm.2021.104458_bib32","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1007\/s12195-009-0072-8","article-title":"Localized intervertebral disc injury leads to organ level changes in structure, cellularity, and biosynthesis","volume":"2","author":"Iatridis","year":"2009","journal-title":"Cell. Mol. Bioeng."},{"key":"10.1016\/j.jmbbm.2021.104458_bib33","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/j.spinee.2012.12.002","article-title":"Role of biomechanics in intervertebral disc degeneration and regenerative therapies: what needs repairing in the disc and what are promising biomaterials for its repair?","volume":"13","author":"Iatridis","year":"2013","journal-title":"Spine J."},{"key":"10.1016\/j.jmbbm.2021.104458_bib34","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1016\/j.ejrad.2015.01.018","article-title":"Spinal pain","volume":"84","author":"Izzo","year":"2015","journal-title":"Eur. J. Radiol."},{"key":"10.1016\/j.jmbbm.2021.104458_bib35","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1046\/j.1469-7580.2003.00249.x","article-title":"Human intervertebral disc cell morphology and cytoskeletal composition: a preliminary study of regional variations in health and disease","volume":"203","author":"Johnson","year":"2003","journal-title":"J. Anat."},{"key":"10.1016\/j.jmbbm.2021.104458_bib36","doi-asserted-by":"crossref","first-page":"1014","DOI":"10.1016\/j.spinee.2010.08.013","article-title":"The effect of needle size inducing degeneration in the rat caudal disc: evaluation using radiograph, magnetic resonance imaging, histology, and immunohistochemistry","volume":"10","author":"Keorochana","year":"2010","journal-title":"Spine J."},{"key":"10.1016\/j.jmbbm.2021.104458_bib37","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/0304-4165(82)90380-4","article-title":"X-ray diffraction demonstrates reorientation of collagen fibres in the annulus fibrosus during compression of the intervertebral disc","volume":"717","author":"Klein","year":"1982","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.jmbbm.2021.104458_bib38","doi-asserted-by":"crossref","first-page":"2198","DOI":"10.1097\/00007632-200110150-00009","article-title":"Acute biomechanical and histological intradiscal electrothermal therapy on human lumbar discs","volume":"20","author":"Kleinstueck","year":"2001","journal-title":"Spine"},{"key":"10.1016\/j.jmbbm.2021.104458_bib39","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.jmbbm.2016.04.033","article-title":"Qualitative and quantitative assessment of collagen and elastin in annulus fibrosus of the physiologic and scoliotic intervertebral discs","volume":"62","author":"Kobielarz","year":"2016","journal-title":"J Mech. Behav. Biomed. Mater."},{"key":"10.1016\/j.jmbbm.2021.104458_bib40","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1097\/BRS.0b013e3181624504","article-title":"Needle puncture injury affects intervertebral disc mechanics and biology in an organ culture model","volume":"33","author":"Korecki","year":"2008","journal-title":"Spine"},{"key":"10.1016\/j.jmbbm.2021.104458_bib41","doi-asserted-by":"crossref","first-page":"4504","DOI":"10.1529\/biophysj.107.114405","article-title":"Quantitative second harmonic generation imaging of the diseased state osteogenesis imperfecta: experiment and simulation","volume":"94","author":"Lacomb","year":"2008","journal-title":"Biophys. J."},{"key":"10.1016\/j.jmbbm.2021.104458_bib42","doi-asserted-by":"crossref","first-page":"1903","DOI":"10.1016\/j.jbiomech.2006.09.002","article-title":"Specimen size effect in the volumetric shrinkage of cancellous bone measured at two levels of dehydration","volume":"40","author":"Lievers","year":"2007","journal-title":"J. Biomech."},{"key":"10.1016\/j.jmbbm.2021.104458_bib43","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1016\/j.medengphy.2010.06.001","article-title":"Effects of dehydration-induced structural and material changes on the apparent modulus of cancellous bone","volume":"328","author":"Lievers","year":"2010","journal-title":"Med. Eng. Phys."},{"key":"10.1016\/j.jmbbm.2021.104458_bib44","doi-asserted-by":"crossref","first-page":"541","DOI":"10.36076\/ppj.2009\/12\/541","article-title":"Systematic Review of lumbar discography as a diagnostic test for chronic low back pain","volume":"12","author":"Manchikanti","year":"2009","journal-title":"Pain Physician"},{"issue":"4","key":"10.1016\/j.jmbbm.2021.104458_bib45","doi-asserted-by":"crossref","DOI":"10.1117\/1.2950318","article-title":"Collagen fiber arrangement in normal and diseased cartilage studied by polarization sensitive nonlinear microscopy","volume":"13","author":"Mansfield","year":"2008","journal-title":"J. Biomed. Opt."},{"key":"10.1016\/j.jmbbm.2021.104458_bib46","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1111\/j.1469-7580.2009.01149.x","article-title":"The elastin network: its relationship with collagen and cells in articular cartilage as visualized by multiphoton microscopy","volume":"215","author":"Mansfield","year":"2009","journal-title":"J. Anat."},{"key":"10.1016\/j.jmbbm.2021.104458_bib47","doi-asserted-by":"crossref","DOI":"10.1098\/rsif.2018.0611","article-title":"Collagen reorganization in cartilage under strain probed by polarization sensitive second harmonic generation microscopy","volume":"16","author":"Mansfield","year":"2019","journal-title":"J. R. Soc. Interface"},{"issue":"4","key":"10.1016\/j.jmbbm.2021.104458_bib48","doi-asserted-by":"crossref","first-page":"675","DOI":"10.2106\/00004623-197456040-00003","article-title":"The structural components of the intervertebral disc. A study of their contributions to the ability of the disc to withstand compressive forces","volume":"56","author":"Markolf","year":"1974","journal-title":"J Bone Joint Surg Am. Jun"},{"key":"10.1016\/j.jmbbm.2021.104458_bib49","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1097\/01.brs.0000148152.04401.20","article-title":"A novel rabbit model of mild, reproducible disc degeneration by an annulus needle puncture: correlation between the degree of disc injury and radiological and histological appearances of disc degeneration","volume":"30","author":"Masuda","year":"2005","journal-title":"Spine"},{"key":"10.1016\/j.jmbbm.2021.104458_bib50","first-page":"143","article-title":"What can biophotonics tell us about the 3D microstructure of articular cartilage?","volume":"5","author":"Matcher","year":"2015","journal-title":"Quant. Imag. Med. Surg."},{"key":"10.1016\/j.jmbbm.2021.104458_bib51","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1016\/j.spinee.2012.04.001","article-title":"Height and torsional stiffness are most sensitive to annular injury in large animal intervertebral discs","volume":"12","author":"Michalek","year":"2012","journal-title":"Spine J."},{"key":"10.1016\/j.jmbbm.2021.104458_bib52","doi-asserted-by":"crossref","first-page":"2110","DOI":"10.1007\/s00586-010-1473-z","article-title":"Needle puncture injury of the rat intervertebral disc affects torsional and compressive biomechanics differently","volume":"19","author":"Michalek","year":"2010","journal-title":"Eur. Spine J."},{"key":"10.1016\/j.jmbbm.2021.104458_bib53","doi-asserted-by":"crossref","first-page":"1098","DOI":"10.1016\/j.spinee.2010.09.015","article-title":"The effects of needle puncture injury on microscale shear strain in the intervertebral disc anulus fibrosus","volume":"10","author":"Michalet","year":"2010","journal-title":"Spine J."},{"key":"10.1016\/j.jmbbm.2021.104458_bib54","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1111\/j.1469-7580.2012.01537.x","article-title":"Characterization of the annulus fibrosus\u2013vertebral body interface: identification of new structural features","volume":"221","author":"Nosikova","year":"2012","journal-title":"J. Anat."},{"key":"10.1016\/j.jmbbm.2021.104458_bib55","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1111\/j.1469-7580.2012.01521.x","article-title":"Diversity of intervertebral disc cells: phenotype and function","volume":"221","author":"Pattappa","year":"2012","journal-title":"J. Anat."},{"key":"10.1016\/j.jmbbm.2021.104458_bib56","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1111\/j.1469-7580.2005.00467.x","article-title":"Intralamellar relationships within the collagenous architecture of the annulus fibrosus imaged in its fully hydrated state","volume":"207","author":"Pezowicz","year":"2005","journal-title":"J. Anat."},{"key":"10.1016\/j.jmbbm.2021.104458_bib57","doi-asserted-by":"crossref","first-page":"E134","DOI":"10.1097\/01.brs.0000155559.24555.fc","article-title":"Intradiscal electrothermal therapy can alter compressive stress distributions inside degenerated intervertebral discs","volume":"30","author":"Pollintine","year":"2005","journal-title":"Spine"},{"key":"10.1016\/j.jmbbm.2021.104458_bib58","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0214072","article-title":"Two-photon fluorescence and second harmonic generation characterization of extracellular matrix remodeling in post-injury murine temporomandibular joint osteoarthritis","volume":"14","author":"Reed","year":"2019","journal-title":"PloS One"},{"key":"10.1016\/j.jmbbm.2021.104458_bib59","doi-asserted-by":"crossref","DOI":"10.1117\/1.2812631","article-title":"Quantitative analysis of structural disorder in intervertebral disks using second harmonic generation imaging: comparison with morphometric analysis","volume":"12","author":"Reiser","year":"2007","journal-title":"J. Biomed. Opt."},{"key":"10.1016\/j.jmbbm.2021.104458_bib60","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1111\/j.1469-7580.2009.01076.x","article-title":"A microstructural investigation of intervertebral disc lamellar connectivity: detailed analysis of the translamellar bridges","volume":"214","author":"Schollum","year":"2007","journal-title":"J. Anat."},{"key":"10.1016\/j.jmbbm.2021.104458_bib61","doi-asserted-by":"crossref","first-page":"E132","DOI":"10.1097\/BRS.0000000000002278","article-title":"A microstructural investigation of disc disruption induced by low frequency cyclic loading","volume":"43","author":"Schollum","year":"2018","journal-title":"Spine"},{"key":"10.1016\/j.jmbbm.2021.104458_bib62","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1042\/bj2520313","article-title":"Proteoglycan-fibrillar collagen interactions","volume":"252","author":"Scott","year":"1988","journal-title":"Biochem. J."},{"key":"10.1016\/j.jmbbm.2021.104458_bib63","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1097\/01.brs.0000148048.15348.9b","article-title":"A slowly progressive and reproducible animal model of intervertebral disc degeneration characterized by MRI, X-ray, and histology","volume":"30","author":"Sobajima","year":"2005","journal-title":"Spine"},{"key":"10.1016\/j.jmbbm.2021.104458_bib64","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/j.actbio.2017.05.036","article-title":"The ultra-structure organization of the elastic network in the intra- and inter-lammellar matric of the intervertebral disc","volume":"58","author":"Tavakoli","year":"2017","journal-title":"Acta Biomater."},{"key":"10.1016\/j.jmbbm.2021.104458_bib65","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1016\/j.bpj.2013.10.044","article-title":"Differentiation of Col I and Col III isoforms in stromal models of ovarian cancer by analysis of second harmonic generation polarization and emission directionality","volume":"106","author":"Tilbury","year":"2014","journal-title":"Biophys. J."},{"key":"10.1016\/j.jmbbm.2021.104458_bib66","doi-asserted-by":"crossref","first-page":"37","DOI":"10.4103\/2152-7806.67107","article-title":"Intradiscal electrothermal therapy in the treatment of chronic low back pain: experience with 93 patients","volume":"1","author":"Tsou","year":"2010","journal-title":"Surg. Neurol."},{"key":"10.1016\/j.jmbbm.2021.104458_bib67","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.actbio.2016.04.002","article-title":"Lamellar and fibre bundle mechanics of the annulus fibrosus in bovine intervertebral disc","volume":"37","author":"Vergari","year":"2016","journal-title":"Acta Biomater."},{"key":"10.1016\/j.jmbbm.2021.104458_bib68","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1016\/j.actbio.2017.09.015","article-title":"The effects of needle damage on annulus fibrosus micromechanics","volume":"63","author":"Vergari","year":"2017","journal-title":"Acta Biomater."},{"key":"10.1016\/j.jmbbm.2021.104458_bib69","doi-asserted-by":"crossref","first-page":"1475","DOI":"10.1007\/s10237-017-0900-z","article-title":"Bovine and degenerated human annulus fibrosus: a microstructural and micromechanical comparison","volume":"16","author":"Vergari","year":"2017","journal-title":"Biomech. Model. Mechanobiol."},{"key":"10.1016\/j.jmbbm.2021.104458_bib70","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1016\/j.joca.2015.03.028","article-title":"Mechanics and biology in intervertebral disc degeneration: a vicious circle","volume":"23","author":"Vergroesen","year":"2015","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.jmbbm.2021.104458_bib71","series-title":"Anaesthesia and Intensive Care A-Z E-Book: an Encyclopedia of Principles and Practice. FRCA Study Guides","isbn-type":"print","author":"Yentis","year":"2013","ISBN":"https:\/\/id.crossref.org\/isbn\/9780702053757"},{"key":"10.1016\/j.jmbbm.2021.104458_bib72","doi-asserted-by":"crossref","first-page":"1134","DOI":"10.1016\/j.spinee.2013.02.010","article-title":"Intervertebral disc degeneration alters lumbar spine segmental stiffness in all modes of loading under a compressive follower load","volume":"13","author":"Zirbel","year":"2013","journal-title":"Spine J."}],"container-title":["Journal of the Mechanical Behavior of Biomedical Materials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1751616121001454?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1751616121001454?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T22:41:42Z","timestamp":1761691302000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1751616121001454"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6]]},"references-count":70,"alternative-id":["S1751616121001454"],"URL":"https:\/\/doi.org\/10.1016\/j.jmbbm.2021.104458","relation":{},"ISSN":["1751-6161"],"issn-type":[{"value":"1751-6161","type":"print"}],"subject":[],"published":{"date-parts":[[2021,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Micro-mechanical damage of needle puncture on bovine annulus fibrosus fibrils studied using polarization-resolved Second Harmonic Generation(P-SHG) microscopy","name":"articletitle","label":"Article Title"},{"value":"Journal of the Mechanical Behavior of Biomedical Materials","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jmbbm.2021.104458","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"104458"}}