{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T00:31:14Z","timestamp":1786494674380,"version":"build-2736575974"},"reference-count":67,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the Mechanical Behavior of Biomedical Materials"],"published-print":{"date-parts":[[2022,5]]},"DOI":"10.1016\/j.jmbbm.2022.105131","type":"journal-article","created":{"date-parts":[[2022,2,14]],"date-time":"2022-02-14T12:26:47Z","timestamp":1644841607000},"page":"105131","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":20,"special_numbering":"C","title":["Mechanical characterization of articular cartilage degraded combinedly with MMP-1 and MMP-9"],"prefix":"10.1016","volume":"129","author":[{"given":"Allison","family":"Mixon","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6434-5679","authenticated-orcid":false,"given":"Ahmed Suparno","family":"Bahar-Moni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3265-7579","authenticated-orcid":false,"given":"Tanvir R.","family":"Faisal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jmbbm.2022.105131_bib1","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1002\/jor.1100120306","article-title":"Comparative study of the intrinsic mechanical properties of the human acetabular and femoral head cartilage","volume":"12","author":"Athanasiou","year":"1994","journal-title":"J. Orthop. Res."},{"key":"10.1016\/j.jmbbm.2022.105131_bib2","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1002\/jor.1100090304","article-title":"Interspecies comparisons of in situ intrinsic mechanical properties of distal femoral cartilage","volume":"9","author":"Athanasiou","year":"1991","journal-title":"J. Orthop. Res."},{"key":"10.1016\/j.jmbbm.2022.105131_bib3","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/S0014-5793(01)02204-9","article-title":"Membrane type 1 matrix metalloproteinase and gelatinase A synergistically degrade type 1 collagen in a cell model","volume":"491","author":"Atkinson","year":"2001","journal-title":"FEBS Lett."},{"key":"10.1016\/j.jmbbm.2022.105131_bib4","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1016\/j.jbiomech.2005.02.018","article-title":"Indentation testing of human articular cartilage: effects of probe tip geometry and indentation depth on intra-tissue strain","volume":"39","author":"Bae","year":"2006","journal-title":"J. Biomech."},{"key":"10.1016\/j.jmbbm.2022.105131_bib5","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.joca.2006.06.007","article-title":"Indentation probing of human articular cartilage: effect on chondrocyte viability","volume":"15","author":"Bae","year":"2007","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.jmbbm.2022.105131_bib6","doi-asserted-by":"crossref","first-page":"1534","DOI":"10.1172\/JCI119316","article-title":"Enhanced cleavage of type II collagen by collagenases in osteoarthritic articular cartilage","volume":"99","author":"Billinghurst","year":"1997","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.jmbbm.2022.105131_bib7","doi-asserted-by":"crossref","DOI":"10.1186\/2042-6410-4-4","article-title":"Addressing the gaps: sex differences in osteoarthritis of the knee","volume":"4","author":"Boyan","year":"2013","journal-title":"Biol. Sex Differ."},{"key":"10.1016\/j.jmbbm.2022.105131_bib8","first-page":"487","article-title":"Articular cartilage: degeneration and osteoarthritis, repair, regeneration, and transplantation","volume":"47","author":"Buckwalter","year":"1998","journal-title":"Instr. Course Lect."},{"key":"10.1016\/j.jmbbm.2022.105131_bib9","doi-asserted-by":"crossref","first-page":"529","DOI":"10.2741\/1817","article-title":"Matrix metalloproteinases: role in arthritis","volume":"11","author":"Burrage","year":"2006","journal-title":"Front. Biosci."},{"key":"10.1016\/j.jmbbm.2022.105131_bib10","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1179\/his.1998.21.1.49","article-title":"Decalcification of bone: literature review and practical study of various decalcifying agents. Methods, and their effects on bone histology","volume":"21","author":"Callis","year":"1998","journal-title":"J. Histotechnol."},{"key":"10.1016\/j.jmbbm.2022.105131_bib11","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1007\/s00441-009-0887-6","article-title":"Proteinases involved in matrix turnover during cartilage and bone breakdown","volume":"339","author":"Cawston","year":"2009","journal-title":"Cell Tissue Res."},{"key":"10.1016\/j.jmbbm.2022.105131_bib12","doi-asserted-by":"crossref","DOI":"10.1115\/1.4000991","article-title":"Effects of refrigeration and freezing on the electromechanical and biomechanical properties of articular cartilage","volume":"132","author":"Changoor","year":"2010","journal-title":"J. Biomech. Eng."},{"key":"10.1016\/j.jmbbm.2022.105131_bib13","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0024029","article-title":"Diffusion of MMPs on the surface of collagen fibrils: the mobile cell surface\u2013collagen substratum interface","volume":"6","author":"Collier","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.jmbbm.2022.105131_bib14","series-title":"Overview of MMP Biology and Gene Associations in Human Diseases","author":"Djurj","year":"2017"},{"key":"10.1016\/j.jmbbm.2022.105131_bib15","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/ar792","article-title":"The triterpenoid CDDO inhibits expression of matrix metalloproteinase-1, matrix metalloproteinase-13 and Bcl-3 in primary human chondrocytes","volume":"5","author":"Elliott","year":"2003","journal-title":"Arthritis Res. Ther."},{"key":"10.1016\/j.jmbbm.2022.105131_bib16","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1152\/jappl.1963.18.2.393","article-title":"Nature of \"imperfect\" elasticity of articular cartilage","volume":"18","author":"Elmore","year":"1963","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.jmbbm.2022.105131_bib17","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1007\/s10237-018-01112-2","article-title":"The effect of fibrillar degradation on the mechanics of articular cartilage: a computational model","volume":"18","author":"Faisal","year":"2019","journal-title":"Biomech. Model. Mechanobiol."},{"key":"10.1016\/j.jmbbm.2022.105131_bib18","doi-asserted-by":"crossref","first-page":"1861","DOI":"10.1002\/term.2936","article-title":"A comparison study of different decellularization treatments on bovine articular cartilage","volume":"13","author":"Ghassemi","year":"2019","journal-title":"J Tissue Eng Regen Med"},{"key":"10.1016\/j.jmbbm.2022.105131_bib72","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1016\/j.jbiomech.2013.11.050","article-title":"An in vitro model for the pathological degradation of articular cartilage in osteoarthritis","volume":"47","author":"Grenier","year":"2014","journal-title":"J. Biomech."},{"key":"10.1016\/j.jmbbm.2022.105131_bib21","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1186\/1471-2474-13-126","article-title":"Matrix metalloproteinase protein expression profiles cannot distinguish between normal and early osteoarthritic synovial fluid","volume":"13","author":"Heard","year":"2012","journal-title":"BMC Muscoskel. Disord."},{"key":"10.1016\/j.jmbbm.2022.105131_bib22","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1016\/0304-4165(73)90093-7","article-title":"The tensile properties of the cartilage of human femoral condyles related to the content of collagen and glycosaminoglycans","volume":"297","author":"Kempson","year":"1973","journal-title":"Biochim. Biophys. Acta Gen. Subj."},{"key":"10.1016\/j.jmbbm.2022.105131_bib23","series-title":"Adult Articular Cartilage. Pitman Medical, Tunbridge Wells","article-title":"Mechanical properties of articular cartilage","author":"Kempson","year":"1979"},{"key":"10.1016\/j.jmbbm.2022.105131_bib24","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1016\/0021-9290(71)90049-2","article-title":"Patterns of cartilage stiffness on normal and degenerate human femoral heads","volume":"4","author":"Kempson","year":"1971","journal-title":"J. Biomech."},{"key":"10.1016\/j.jmbbm.2022.105131_bib25","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1002\/jor.1100070406","article-title":"The effect of cryopreservation on the biomechanical behavior of bovine articular cartilage","volume":"7","author":"Kiefer","year":"1989","journal-title":"J. Orthop. Res."},{"key":"10.1016\/j.jmbbm.2022.105131_bib26","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1016\/j.joca.2004.12.003","article-title":"Human articular chondrocytes exhibit sexual dimorphism in their responses to 17\u03b2-estradiol","volume":"13","author":"Kinney","year":"2005","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.jmbbm.2022.105131_bib27","doi-asserted-by":"crossref","first-page":"17124","DOI":"10.1074\/jbc.271.29.17124","article-title":"Cellular mechanisms for human procollagenase-3 (MMP-13) activation: evidence that MT1-MMP (MMP-14) and gelatinase A (MMP-2) are able to generate active enzyme","volume":"271","author":"Kn\u00e4uper","year":"1996","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.jmbbm.2022.105131_bib28","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1016\/S0021-9290(02)00052-0","article-title":"Comparison of the equilibrium response of articular cartilage in unconfined compression, confined compression and indentation","volume":"35","author":"Korhonen","year":"2002","journal-title":"J. Biomech."},{"key":"10.1016\/j.jmbbm.2022.105131_bib29","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1016\/j.joca.2012.11.008","article-title":"Knee joint loading during gait in healthy controls and individuals with knee osteoarthritis","volume":"21","author":"Kumar","year":"2013","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.jmbbm.2022.105131_bib30","first-page":"133","article-title":"Biomechanical properties of knee articular cartilage","volume":"40","author":"Laasanen","year":"2003","journal-title":"Biorheology"},{"key":"10.1016\/j.jmbbm.2022.105131_bib31","doi-asserted-by":"crossref","first-page":"1076","DOI":"10.3390\/cells9051076","article-title":"Structure and function of human matrix metalloproteinases","volume":"9","author":"Laronha","year":"2020","journal-title":"Cells"},{"key":"10.1016\/j.jmbbm.2022.105131_bib32","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1183\/09031936.00146510","article-title":"Biological role of matrix metalloproteinases: a critical balance","volume":"38","author":"L\u00f6ffek","year":"2011","journal-title":"Eur. Respir. J."},{"key":"10.1016\/j.jmbbm.2022.105131_bib33","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.jbiomech.2015.12.016","article-title":"Alterations in knee contact forces and centers in stance phase of gait: a detailed lower extremity musculoskeletal model","volume":"49","author":"Marouane","year":"2016","journal-title":"J. Biomech."},{"key":"10.1016\/j.jmbbm.2022.105131_bib34","doi-asserted-by":"crossref","first-page":"116786","DOI":"10.1016\/j.lfs.2019.116786","article-title":"The role of matrix metalloproteinases in osteoarthritis pathogenesis: an updated review","volume":"234","author":"Mehana","year":"2019","journal-title":"Life Sci."},{"key":"10.1016\/j.jmbbm.2022.105131_bib35","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0187583","article-title":"Medial knee loading is altered in subjects with early osteoarthritis during gait but not during step-up-and-over task","volume":"12","author":"Meireles","year":"2017","journal-title":"PLoS One"},{"key":"10.1016\/j.jmbbm.2022.105131_bib36","doi-asserted-by":"crossref","first-page":"14409","DOI":"10.1038\/s41598-021-93744-1","article-title":"An in vitro investigation to understand the synergistic role of MMPs-1 and 9 on articular cartilage biomechanical properties","volume":"11","author":"Mixon","year":"2021","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jmbbm.2022.105131_bib37","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1016\/j.ceb.2004.07.010","article-title":"Regulation of matrix biology by matrix metalloproteinases","volume":"16","author":"Mott","year":"2004","journal-title":"Curr. Opin. Cell Biol."},{"key":"10.1016\/j.jmbbm.2022.105131_bib38","doi-asserted-by":"crossref","first-page":"iv44","DOI":"10.1136\/ard.2005.042465","article-title":"What are the roles of metalloproteinases in cartilage and bone damage?","volume":"64","author":"Murphy","year":"2005","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.jmbbm.2022.105131_bib39","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1016\/j.cardiores.2005.12.002","article-title":"Structure and function of matrix metalloproteinases and TIMPs","volume":"69","author":"Nagase","year":"2006","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.jmbbm.2022.105131_bib40","doi-asserted-by":"crossref","first-page":"44","DOI":"10.3109\/03008207.2015.1099636","article-title":"Association study of MMP8 gene in osteoarthritis","volume":"57","author":"N\u00e4kki","year":"2016","journal-title":"Connect. Tissue Res."},{"key":"10.1016\/j.jmbbm.2022.105131_bib41","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0224231","article-title":"An ex vivo tissue model of cartilage degradation suggests that cartilage state can be determined from secreted key protein patterns","volume":"14","author":"Neidlin","year":"2019","journal-title":"PLoS One"},{"key":"10.1016\/j.jmbbm.2022.105131_bib42","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1136\/ard.57.4.237","article-title":"Articular cartilage superficial zone collagen birefringence reduced and cartilage thickness increased before surface fibrillation in experimental osteoarthritis","volume":"57","author":"Panula","year":"1998","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.jmbbm.2022.105131_bib43","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1089\/ten.tec.2019.0116","article-title":"A systematic review and guide to mechanical testing for articular cartilage tissue engineering","volume":"25","author":"Patel","year":"2019","journal-title":"Tissue Eng. C Methods"},{"key":"10.1016\/j.jmbbm.2022.105131_bib44","doi-asserted-by":"crossref","first-page":"3406","DOI":"10.1016\/j.jbiomech.2015.05.032","article-title":"The distribution of superficial zone protein (SZP)\/lubricin\/PRG4 and boundary mode frictional properties of the bovine diarthrodial joint","volume":"48","author":"Peng","year":"2015","journal-title":"J. Biomech."},{"key":"10.1016\/j.jmbbm.2022.105131_bib45","series-title":"Arthritis and Allied Conditions: a Textbook of Rheumatology","first-page":"226","article-title":"Cartilage in health and disease","author":"Pool","year":"2001"},{"key":"10.1016\/j.jmbbm.2022.105131_bib73","doi-asserted-by":"crossref","first-page":"1809","DOI":"10.1007\/s10237-019-01178-6","article-title":"Effect of collagenase-gelatinase ratio on the mechanical properties of a collagen fibril: a combined Monte Carlo-molecular dynamics study","volume":"18","author":"Powell","year":"2019","journal-title":"Biomech. Model. Mechanobiol."},{"key":"10.1016\/j.jmbbm.2022.105131_bib48","doi-asserted-by":"crossref","first-page":"109304","DOI":"10.1016\/j.jbiomech.2019.07.048","article-title":"Compressive fatigue and endurance of juvenile bovine articular cartilage explants","volume":"95","author":"Riemenschneider","year":"2019","journal-title":"J. Biomech."},{"key":"10.1016\/j.jmbbm.2022.105131_bib49","doi-asserted-by":"crossref","first-page":"4895050","DOI":"10.1155\/2016\/4895050","article-title":"A tale of two joints: the role of matrix metalloproteases in cartilage biology","volume":"2016","author":"Rose","year":"2016","journal-title":"Dis. Markers"},{"key":"10.1016\/j.jmbbm.2022.105131_bib50","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0011043","article-title":"Direct visualization of protease action on collagen triple helical structure","volume":"5","author":"Rosenblum","year":"2010","journal-title":"PLoS One"},{"key":"10.1016\/j.jmbbm.2022.105131_bib51","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1016\/j.ultrasmedbio.2004.03.005","article-title":"Ultrasonic quantitation of superficial degradation of articular cartilage","volume":"30","author":"Saarakkala","year":"2004","journal-title":"Ultrasound Med. Biol."},{"key":"10.1016\/j.jmbbm.2022.105131_bib52","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1016\/j.cub.2012.04.012","article-title":"Single-molecule tracking of collagenase on native type I collagen fibrils reveals degradation mechanism","volume":"22","author":"Sarkar","year":"2012","journal-title":"Curr. Biol."},{"key":"10.1016\/j.jmbbm.2022.105131_bib53","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1002\/jor.1100080307","article-title":"Effects of proteoglycan extraction on the tensile behavior of articular cartilage","volume":"8","author":"Schmidt","year":"1990","journal-title":"J. Orthop. Res."},{"key":"10.1016\/j.jmbbm.2022.105131_bib54","doi-asserted-by":"crossref","first-page":"S113","DOI":"10.1016\/j.joca.2010.05.026","article-title":"Basic methods in histopathology of joint tissues","volume":"18","author":"Schmitz","year":"2010","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.jmbbm.2022.105131_bib55","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1111\/j.1440-1827.2010.02547.x","article-title":"Matrix metalloproteinases, a disintegrin and metalloproteinases, and a disintegrin and metalloproteinases with thrombospondin motifs in non\u2010neoplastic diseases","volume":"60","author":"Shiomi","year":"2010","journal-title":"Pathol. Int."},{"key":"10.1016\/j.jmbbm.2022.105131_bib56","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1038\/nrm2821","article-title":"Regulation of cell signalling by uPAR","volume":"11","author":"Smith","year":"2010","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.jmbbm.2022.105131_bib57","doi-asserted-by":"crossref","first-page":"D704","DOI":"10.2741\/A388","article-title":"Degradative enzymes in osteoarthritis","volume":"4","author":"Smith","year":"1999","journal-title":"Front. Biosci."},{"key":"10.1016\/j.jmbbm.2022.105131_bib58","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41467-017-01868-8","article-title":"Estrogen-related receptor \u03b3 causes osteoarthritis by upregulating extracellular matrix-degrading enzymes","volume":"8","author":"Son","year":"2017","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jmbbm.2022.105131_bib59","doi-asserted-by":"crossref","first-page":"24","DOI":"10.2174\/1874312901206010024","article-title":"Histological examination of collagen and proteoglycan changes in osteoarthritic menisci","volume":"6","author":"Sun","year":"2012","journal-title":"Open Rheumatol. J."},{"key":"10.1016\/j.jmbbm.2022.105131_bib60","series-title":"The Effect of Mechanical Stress on the Stiffness of Articular Cartilage and its Role in the Aetiology of Osteoarthrosis","author":"Swann","year":"1988"},{"key":"10.1016\/j.jmbbm.2022.105131_bib61","first-page":"1","article-title":"Freeze-thaw treatment effects on the dynamic mechanical properties of articular cartilage","volume":"11","author":"Szarko","year":"2010","journal-title":"BMC Muscoskel. Disord."},{"key":"10.1016\/j.jmbbm.2022.105131_bib62","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1136\/ard.2004.022434","article-title":"MMP protein and activity levels in synovial fluid from patients with joint injury, inflammatory arthritis, and osteoarthritis","volume":"64","author":"Tchetverikov","year":"2005","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.jmbbm.2022.105131_bib63","doi-asserted-by":"crossref","first-page":"281","DOI":"10.3109\/03008200109016842","article-title":"Collagen-binding domain of a Clostridium histolyticum collagenase exhibits a broad substrate spectrum both in vitro and in vivo","volume":"42","author":"Toyoshima","year":"2001","journal-title":"Connect. Tissue Res."},{"key":"10.1016\/j.jmbbm.2022.105131_bib64","doi-asserted-by":"crossref","first-page":"2723","DOI":"10.1088\/0031-9155\/44\/11\/303","article-title":"Characterization of enzymatically induced degradation of articular cartilage using high frequency ultrasound","volume":"44","author":"T\u00f6yr\u00e4s","year":"1999","journal-title":"Phys. Med. Biol."},{"key":"10.1016\/j.jmbbm.2022.105131_bib65","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.bbapap.2011.06.020","article-title":"Proteases involved in cartilage matrix degradation in osteoarthritis","volume":"1824","author":"Troeberg","year":"2012","journal-title":"Biochim. Biophys. Acta Protein Proteonomics"},{"key":"10.1016\/j.jmbbm.2022.105131_bib66","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.1016\/j.ultrasmedbio.2007.12.006","article-title":"Real-time ultrasonic assessment of progressive proteoglycan depletion in articular cartilage","volume":"34","author":"Wang","year":"2008","journal-title":"Ultrasound Med. Biol."},{"key":"10.1016\/j.jmbbm.2022.105131_bib67","doi-asserted-by":"crossref","first-page":"954","DOI":"10.2106\/00004623-197254050-00002","article-title":"An ultrastructural study of osteoarthritic changes in the articular cartilage of human knees","volume":"54","author":"Weiss","year":"1972","journal-title":"JBJS"},{"key":"10.1016\/j.jmbbm.2022.105131_bib68","doi-asserted-by":"crossref","first-page":"2159","DOI":"10.1159\/000479991","article-title":"Kr\u00fcppel-like factor 2 regulates degradation of type II collagen by suppressing the expression of matrix metalloproteinase (MMP)-13","volume":"42","author":"Yuan","year":"2017","journal-title":"Cell. Physiol. Biochem."},{"key":"10.1016\/j.jmbbm.2022.105131_bib69","doi-asserted-by":"crossref","first-page":"14811","DOI":"10.4238\/2015.November.18.46","article-title":"High MMP-1, MMP-2, and MMP-9 protein levels in osteoarthritis","volume":"14","author":"Zeng","year":"2015","journal-title":"Genet. Mol. Res."}],"container-title":["Journal of the Mechanical Behavior of Biomedical Materials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1751616122000558?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1751616122000558?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T22:43:08Z","timestamp":1761691388000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1751616122000558"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5]]},"references-count":67,"alternative-id":["S1751616122000558"],"URL":"https:\/\/doi.org\/10.1016\/j.jmbbm.2022.105131","relation":{},"ISSN":["1751-6161"],"issn-type":[{"value":"1751-6161","type":"print"}],"subject":[],"published":{"date-parts":[[2022,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Mechanical characterization of articular cartilage degraded combinedly with MMP-1 and MMP-9","name":"articletitle","label":"Article Title"},{"value":"Journal of the Mechanical Behavior of Biomedical Materials","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jmbbm.2022.105131","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"105131"}}