{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T16:16:42Z","timestamp":1787242602875,"version":"build-2736575974"},"reference-count":47,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the Mechanical Behavior of Biomedical Materials"],"published-print":{"date-parts":[[2022,7]]},"DOI":"10.1016\/j.jmbbm.2022.105202","type":"journal-article","created":{"date-parts":[[2022,4,13]],"date-time":"2022-04-13T11:44:29Z","timestamp":1649850269000},"page":"105202","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"special_numbering":"C","title":["A finite element study on femoral locking compression plate design using genetic optimization method"],"prefix":"10.1016","volume":"131","author":[{"given":"R.","family":"Rostamian","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1709-3621","authenticated-orcid":false,"given":"M.","family":"Silani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1088-9814","authenticated-orcid":false,"given":"S.","family":"Ziaei-Rad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"Busse","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Qwamizadeh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Rabczuk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jmbbm.2022.105202_bib1","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1016\/j.injury.2006.08.058","article-title":"Biomechanical testing of the locking compression plate : when does the distance between bone and implant significantly reduce construct stability","volume":"38","author":"Ahmad","year":"2007","journal-title":"Injury"},{"key":"10.1016\/j.jmbbm.2022.105202_bib2","series-title":"3rd CIRP Conference on BioManufacturing","first-page":"202","article-title":"Topology Optimization to reduce the stress shielding effect for orthopedic applications","author":"Al-tamimi","year":"2017"},{"key":"10.1016\/j.jmbbm.2022.105202_bib3","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1016\/j.medengphy.2007.12.009","article-title":"Comparison of an inhomogeneous orthotropic and isotropic material models used for FE analyses","volume":"30","author":"Baca","year":"2008","journal-title":"Med. Eng. Phys."},{"key":"10.1016\/j.jmbbm.2022.105202_bib4","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1016\/S0021-9290(01)00040-9","article-title":"Hip forces and gait patterns from rountine activities","volume":"34","author":"Bergmann","year":"2001","journal-title":"J. Biomech."},{"key":"10.1016\/j.jmbbm.2022.105202_bib5","series-title":"Rockwood and Green's Fractures in Adults","author":"Bucholz","year":"2010"},{"key":"10.1016\/j.jmbbm.2022.105202_bib6","doi-asserted-by":"crossref","first-page":"1964","DOI":"10.2106\/00004623-200709000-00011","article-title":"Locking compression plate fixation of Vancouver type-B1 periprosthetic femoral fractures","volume":"89","author":"Buttaro","year":"2007","journal-title":"J. Bone Joint Surg. Am."},{"key":"10.1016\/j.jmbbm.2022.105202_bib7","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1243\/09544119JEIM670","article-title":"Computational investigations of mechanical failures of internal plate fixation","volume":"224","author":"Chen","year":"2010","journal-title":"Proc. Inst. Mech. Eng. H."},{"key":"10.1016\/j.jmbbm.2022.105202_bib8","first-page":"85","article-title":"Parametric design of patient-specific fixation plates for distal femur fractures","volume":"31","author":"Chen","year":"2018","journal-title":"J. Eng. Med."},{"key":"10.1016\/j.jmbbm.2022.105202_bib9","first-page":"502","article-title":"A novel computer-aided approach for parametric investigation of custom design of fracture fixation plates","volume":"7","author":"Chen","year":"2017","journal-title":"Comput. Math. Methods Med."},{"key":"10.1016\/j.jmbbm.2022.105202_bib10","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/S0021-9290(98)00153-5","article-title":"Magnitudes of local stress and strain along bony surfaces predict the course and type of fracture healing","volume":"32","author":"Claes","year":"1999","journal-title":"J. Biomech."},{"key":"10.1016\/j.jmbbm.2022.105202_bib11","doi-asserted-by":"crossref","first-page":"3319","DOI":"10.1098\/rsta.2008.0077","article-title":"Multiscale investigation of the functional properties of the human femur","volume":"366","author":"Cristofolini","year":"2008","journal-title":"Philos. Trans. R. Soc. A Math. Phys. Eng. Sci."},{"key":"10.1016\/j.jmbbm.2022.105202_bib12","author":"DePuy"},{"key":"10.1016\/j.jmbbm.2022.105202_bib13","unstructured":"Femur shaft [WWW Document], n.d. URL https:\/\/surgeryreference.aofoundation.org\/orthopedic-trauma\/adult-trauma\/femoral-shaft (accessed 7.15.21)."},{"key":"10.1016\/j.jmbbm.2022.105202_bib14","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1016\/j.medengphy.2010.11.013","article-title":"Assessment of function-graded materials as fracture fixation bone-plates under combined loading conditions using finite element modelling","volume":"33","author":"Fouad","year":"2011","journal-title":"Med. Eng. Phys."},{"key":"10.1016\/j.jmbbm.2022.105202_bib15","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.injury.2003.09.026","article-title":"Guidelines for the clinical application of the LCP","volume":"34","author":"Gautier","year":"2003","journal-title":"Injury"},{"key":"10.1016\/j.jmbbm.2022.105202_bib16","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1302\/0301-620X.67B4.4030869","article-title":"The influence of induced micromovement upon the healing of experimental tibial fractures","volume":"67","author":"Goodship","year":"1985","journal-title":"J. Bone Joint Surg. Br."},{"key":"10.1016\/j.jmbbm.2022.105202_bib17","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1299\/jbse.5.129","article-title":"A discussion on plating factors that affect stress shielding using finite element analysis","volume":"5","author":"Haase","year":"2010","journal-title":"J. Biomech. Sci. Eng."},{"key":"10.1016\/j.jmbbm.2022.105202_bib18","first-page":"581","article-title":"Preoperative planning in orthopedic trauma: benefits and contemporary uses","volume":"33","author":"Hak","year":"2010","journal-title":"Truma Updat"},{"key":"10.1016\/j.jmbbm.2022.105202_bib19","series-title":"Basic Biomechanics","author":"Hall","year":"2007"},{"key":"10.1016\/j.jmbbm.2022.105202_bib20","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1016\/j.medengphy.2007.05.006","article-title":"A modified method for assigning material properties to FE models of bones","volume":"30","author":"Helgason","year":"2008","journal-title":"Med. Eng. Phys."},{"key":"10.1016\/j.jmbbm.2022.105202_bib21","first-page":"491","article-title":"Applications of finite element methods and discrete particle swarm optimization algorithms in design of locked compression plates","volume":"9","author":"Hsu","year":"2012","journal-title":"Comput. Des."},{"key":"10.1016\/j.jmbbm.2022.105202_bib22","article-title":"Implicit modeling of screw threads for ef fi cient fi nite element analysis of complex bone-implant systems","volume":"1\u20139","author":"Inzana","year":"2016","journal-title":"J. Biomech."},{"key":"10.1016\/j.jmbbm.2022.105202_bib23","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/S0030-5898(20)32286-0","article-title":"Distal femoral fractures","volume":"1","author":"Johnson","year":"1987","journal-title":"Orthop. Clin. N. Am."},{"key":"10.1016\/j.jmbbm.2022.105202_bib24","first-page":"522","article-title":"Simulation-based particle swarm optimization and mechanical validation of screw position and number for the fixation stability of a femoral locking compression plate","volume":"20","author":"Lee","year":"2013","journal-title":"Med. Eng. Phys."},{"key":"10.1016\/j.jmbbm.2022.105202_bib25","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/j.injury.2014.10.060","article-title":"The biomechanical effect of bone quality and fracture topography on locking plate fixation in periprosthetic femoral fractures","volume":"46","author":"Leonidou","year":"2015","journal-title":"Injury"},{"key":"10.1016\/j.jmbbm.2022.105202_bib26","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.2106\/00004623-200606000-00007","article-title":"Three hundred and twenty-one periprosthetic femoral fractures","volume":"88-A","author":"Lindahl","year":"2006","journal-title":"J. Bone Jt. Surg."},{"key":"10.1016\/j.jmbbm.2022.105202_bib27","first-page":"26","article-title":"Risk factors for failure after treatment of a periprosthetic fracture of the femur","volume":"8","author":"Lindahl","year":"2000","journal-title":"J. Bone Jt. Surg."},{"key":"10.1016\/j.jmbbm.2022.105202_bib28","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1097\/BOT.0b013e3181be6720","article-title":"Locked plating of distal femur fractures leads to inconsistent and asymmetric callus formation","volume":"24","author":"Lujan","year":"2010","journal-title":"J. Orthop. Trauma"},{"key":"10.1016\/j.jmbbm.2022.105202_bib29","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1016\/j.clinbiomech.2007.08.004","article-title":"A review of locking compression plate biomechanics and their advantages as internal fixators in fracture healing","volume":"22","author":"Miller","year":"2007","journal-title":"Clin. Biomech."},{"key":"10.1016\/j.jmbbm.2022.105202_bib30","doi-asserted-by":"crossref","first-page":"3758","DOI":"10.3390\/jcm9113758","article-title":"High failure rates of locking compression plate osteosynthesis with transverse fracture around a well-fixed stem tip for periprosthetic femoral fracture","volume":"9","author":"Min","year":"2020","journal-title":"J. Clin. Med."},{"key":"10.1016\/j.jmbbm.2022.105202_bib31","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1002\/cplx.6130010108","article-title":"Genetic algorithms: an overview","volume":"1","author":"Mitchell","year":"1995","journal-title":"Complexity"},{"key":"10.1016\/j.jmbbm.2022.105202_bib32","unstructured":"Mixed Integer ga Optimization - MATLAB & Simulink - MathWorks Deutschland [WWW Document], n.d. URL https:\/\/de.mathworks.com\/help\/gads\/mixed-integer-optimization.html (accessed 7.6.21)."},{"key":"10.1016\/j.jmbbm.2022.105202_bib33","doi-asserted-by":"crossref","first-page":"590","DOI":"10.4236\/jbise.2015.89055","article-title":"The effects of bone screw configurations on the interfragmentary movement in a long bone fixed by a limited contact locking compression plate","volume":"8","author":"Nourisa","year":"2015","journal-title":"J. Biomed. Sci. Eng."},{"key":"10.1016\/j.jmbbm.2022.105202_bib34","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.advengsoft.2017.01.006","article-title":"Abaqus2Matlab : a suitable tool for finite element post-processing","volume":"105","author":"Papazafeiropoulos","year":"2017","journal-title":"Adv. Eng. Software"},{"key":"10.1016\/j.jmbbm.2022.105202_bib35","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1302\/0301-620X.84B8.0841093","article-title":"Evolution of the internal fixation of long bone fractures. The scientific basis of biological internal fixation: choosing a new balance between stability and biology","volume":"84","author":"Perren","year":"2002","journal-title":"J. Bone Joint Surg. Br."},{"key":"10.1016\/j.jmbbm.2022.105202_bib36","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1177\/0954411912467884","article-title":"Patient-specific finite element modeling of bones","volume":"227","author":"Poelert","year":"2013","journal-title":"J. Eng. Med."},{"key":"10.1016\/j.jmbbm.2022.105202_bib37","doi-asserted-by":"crossref","DOI":"10.1155\/2019\/5636528","article-title":"Finite element-and design of experiment-derived optimization of screw configurations and a locking plate for internal fixation system","volume":"2019","author":"Sheng","year":"2019","journal-title":"Comput. Math. Methods Med"},{"key":"10.1016\/j.jmbbm.2022.105202_bib38","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.injury.2003.09.021","article-title":"Biomechanical testing of the LCP \u2013 how can stability in locked internal fixators be controlled","volume":"34","author":"Stoffel","year":"2003","journal-title":"Injury"},{"key":"10.1016\/j.jmbbm.2022.105202_bib39","series-title":"Matec Web of Conferences","first-page":"4","article-title":"Screw layout optimization to solve fatigue fracture of femoral Ti alloy metal plate","author":"Tian","year":"2016"},{"key":"10.1016\/j.jmbbm.2022.105202_bib40","doi-asserted-by":"crossref","first-page":"2951","DOI":"10.1016\/j.jbiomech.2005.10.027","article-title":"Comparison of micro-level and continuum-level voxel models of the proximal femur","volume":"39","author":"Verhulp","year":"2006","journal-title":"J. Biomech."},{"key":"10.1016\/j.jmbbm.2022.105202_bib41","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1016\/S0268-0033(03)00072-X","article-title":"Experimental investigation of bone remodelling using composite femurs","volume":"18","author":"Waide","year":"2003","journal-title":"Clin. Biomech."},{"key":"10.1016\/j.jmbbm.2022.105202_bib42","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0115695","article-title":"Prediction of the time course of callus stiffness as a function of mechanical parameters in experimental rat fracture healing studies--a numerical study","volume":"9","author":"Wehner","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.jmbbm.2022.105202_bib43","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1371\/journal.pone.0033776","article-title":"Finite element analysis of osteosynthesis screw fixation in the bone stock : an appropriate method for automatic screw modelling","volume":"7","author":"Wieding","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.jmbbm.2022.105202_bib44","doi-asserted-by":"crossref","first-page":"842","DOI":"10.3844\/ajassp.2012.842.845","article-title":"The effect of the configuration of the screw fixation on the interfragmentary strain boonthum wongchai department of mechanical engineering , faculty of engineering at Si racha","volume":"9","author":"Wongchai","year":"2012","journal-title":"Am. J. Appl. Sci."},{"key":"10.1016\/j.jmbbm.2022.105202_bib45","doi-asserted-by":"crossref","first-page":"466","DOI":"10.3844\/jcssp.2011.466.470","article-title":"Stress prediction in the dynamic compression plate with changing the configuration of the screw fixation","volume":"7","author":"Wongchai","year":"2011","journal-title":"J. Comput. Sci."},{"key":"10.1016\/j.jmbbm.2022.105202_bib46","first-page":"8","article-title":"Clinical effect of locking compression plate via posterolateral approach in the treatment of distal femoral fractures : a new approach","author":"Xing","year":"2018","journal-title":"J. Orthop. Surg. Res."},{"key":"10.1016\/j.jmbbm.2022.105202_bib47","first-page":"1","article-title":"Iterative approach for 3D reconstruction of the femur from un-calibrated 2D radiographic images Kibeom","author":"Youn","year":"2017","journal-title":"Med. Eng. Phys."}],"container-title":["Journal of the Mechanical Behavior of Biomedical Materials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1751616122001205?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1751616122001205?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T22:44:20Z","timestamp":1761691460000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1751616122001205"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,7]]},"references-count":47,"alternative-id":["S1751616122001205"],"URL":"https:\/\/doi.org\/10.1016\/j.jmbbm.2022.105202","relation":{},"ISSN":["1751-6161"],"issn-type":[{"value":"1751-6161","type":"print"}],"subject":[],"published":{"date-parts":[[2022,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A finite element study on femoral locking compression plate design using genetic optimization method","name":"articletitle","label":"Article Title"},{"value":"Journal of the Mechanical Behavior of Biomedical Materials","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jmbbm.2022.105202","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"105202"}}