{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T03:26:18Z","timestamp":1793762778562,"version":"4.6.1"},"reference-count":68,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,4,10]],"date-time":"2023-04-10T00:00:00Z","timestamp":1681084800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the Mechanical Behavior of Biomedical Materials"],"published-print":{"date-parts":[[2023,6]]},"DOI":"10.1016\/j.jmbbm.2023.105843","type":"journal-article","created":{"date-parts":[[2023,4,17]],"date-time":"2023-04-17T11:58:02Z","timestamp":1681732682000},"page":"105843","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"special_numbering":"C","title":["Physical confinement and cell proximity increase cell migration rates and invasiveness: A mathematical model of cancer cell invasion through flexible channels"],"prefix":"10.1016","volume":"142","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7077-0727","authenticated-orcid":false,"given":"Qiyao","family":"Peng","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2212-1711","authenticated-orcid":false,"given":"Fred J.","family":"Vermolen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9670-3418","authenticated-orcid":false,"given":"Daphne","family":"Weihs","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jmbbm.2023.105843_b1","doi-asserted-by":"crossref","first-page":"303","DOI":"10.7150\/ijbs.3.303","article-title":"The forces behind cell movement","author":"Ananthakrishnan","year":"2007","journal-title":"Int. J. Biol. Sci."},{"key":"10.1016\/j.jmbbm.2023.105843_b2","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1039\/c2fd00130f","article-title":"Cell friction","volume":"156","author":"Angelini","year":"2012","journal-title":"Faraday Discuss."},{"issue":"111","key":"10.1016\/j.jmbbm.2023.105843_b3","doi-asserted-by":"crossref","DOI":"10.1098\/rsif.2015.0343","article-title":"Morpho-elasticity of inflammatory fibrosis: the case of capsular contracture","volume":"12","author":"Ben Amar","year":"2015","journal-title":"J. R. Soc. Interface"},{"issue":"51","key":"10.1016\/j.jmbbm.2023.105843_b4","doi-asserted-by":"crossref","first-page":"20275","DOI":"10.1073\/pnas.1116814108","article-title":"Crawling cell locomotion revisited","volume":"108","author":"Bershadsky","year":"2011","journal-title":"Proc. Natl. Acad. Sci."},{"issue":"5","key":"10.1016\/j.jmbbm.2023.105843_b5","doi-asserted-by":"crossref","first-page":"1429","DOI":"10.1007\/s10237-018-1036-5","article-title":"A phenomenological model for cell and nucleus deformation during cancer metastasis","volume":"17","author":"Chen","year":"2018","journal-title":"Biomech. Model. Mechanobiol."},{"key":"10.1016\/j.jmbbm.2023.105843_b6","first-page":"1","article-title":"A model for cell migration in non-isotropic fibrin networks with an application to pancreatic tumor islets","author":"Chen","year":"2017","journal-title":"Biomech. Model. Mechanobiol."},{"issue":"12","key":"10.1016\/j.jmbbm.2023.105843_b7","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1038\/nnano.2007.388","article-title":"Nanomechanical analysis of cells from cancer patients","volume":"2","author":"Cross","year":"2007","journal-title":"Nature Nanotechnol."},{"key":"10.1016\/j.jmbbm.2023.105843_b8","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.jtbi.2018.09.008","article-title":"A coupled bulk-surface model for cell polarisation","volume":"481","author":"Cusseddu","year":"2019","journal-title":"J. Theoret. Biol."},{"issue":"1","key":"10.1016\/j.jmbbm.2023.105843_b9","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1146\/annurev.cb.04.110188.003245","article-title":"Chemotaxis in eukaryotic cells: A focus on leukocytes and dictyostelium","volume":"4","author":"Devreotes","year":"1988","journal-title":"Annu. Rev. Cell Biol."},{"issue":"1","key":"10.1016\/j.jmbbm.2023.105843_b10","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-018-23540-x","article-title":"Persistent random deformation model of cells crawling on a gel surface","volume":"8","author":"Ebata","year":"2018","journal-title":"Sci. Rep."},{"issue":"3","key":"10.1016\/j.jmbbm.2023.105843_b11","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1007\/s12013-012-9356-z","article-title":"Intracellular mechanics and activity of breast cancer cells correlate with metastatic potential","volume":"63","author":"Gal","year":"2012","journal-title":"Cell Biochem. Biophys."},{"issue":"9","key":"10.1016\/j.jmbbm.2023.105843_b12","doi-asserted-by":"crossref","first-page":"828","DOI":"10.1016\/j.medengphy.2016.05.014","article-title":"Cytoskeleton and plasma-membrane damage resulting from exposure to sustained deformations: A review of the mechanobiology of chronic wounds","volume":"38","author":"Gefen","year":"2016","journal-title":"Med. Eng. Phys."},{"key":"10.1016\/j.jmbbm.2023.105843_b13","series-title":"New Trends in the Physics and Mechanics of Biological Systems: Lecture Notes of the Les Houches Summer School: Volume 92, July 2009","first-page":"153","article-title":"Morphoelasticity: a theory of elastic growth","author":"Goriely","year":"2011"},{"issue":"5","key":"10.1016\/j.jmbbm.2023.105843_b14","doi-asserted-by":"crossref","first-page":"3689","DOI":"10.1529\/biophysj.104.045476","article-title":"Optical deformability as an inherent cell marker for testing malignant transformation and metastatic competence","volume":"88","author":"Guck","year":"2005","journal-title":"Biophys. J."},{"key":"10.1016\/j.jmbbm.2023.105843_b15","series-title":"Modelling of Some Biological Materials Using Continuum Mechanics","author":"Hall","year":"2008"},{"issue":"6","key":"10.1016\/j.jmbbm.2023.105843_b16","doi-asserted-by":"crossref","DOI":"10.1242\/jcs.214015","article-title":"How cells sense their own shape \u2013 mechanisms to probe cell geometry and their implications in cellular organization and function","volume":"131","author":"Haupt","year":"2018","journal-title":"J. Cell Sci."},{"issue":"4","key":"10.1016\/j.jmbbm.2023.105843_b17","doi-asserted-by":"crossref","first-page":"1177","DOI":"10.1007\/s10237-019-01136-2","article-title":"Modelling actin polymerization: the effect on confined cell migration","volume":"18","author":"Hervas-Raluy","year":"2019","journal-title":"Biomech. Model. Mechanobiol."},{"key":"10.1016\/j.jmbbm.2023.105843_b18","series-title":"Methods in Molecular Biology","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1007\/978-1-61779-207-6_28","article-title":"Cell migration in confinement: A micro-channel-based assay","author":"Heuz\u00e9","year":"2011"},{"key":"10.1016\/j.jmbbm.2023.105843_b19","series-title":"Methods in Cell Biology","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/B978-0-12-800281-0.00010-5","article-title":"Cell migration in confined environments","author":"Irimia","year":"2014"},{"issue":"12","key":"10.1016\/j.jmbbm.2023.105843_b20","doi-asserted-by":"crossref","first-page":"1393","DOI":"10.1038\/ncb1797","article-title":"Fluctuations of intracellular forces during cell protrusion","volume":"10","author":"Ji","year":"2008","journal-title":"Nature Cell Biol."},{"issue":"7194","key":"10.1016\/j.jmbbm.2023.105843_b21","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1038\/nature06952","article-title":"Mechanism of shape determination in motile cells","volume":"453","author":"Keren","year":"2008","journal-title":"Nature"},{"issue":"1","key":"10.1016\/j.jmbbm.2023.105843_b22","article-title":"A computational modeling of invadopodia protrusion into an extracellular matrix fiber network","volume":"12","author":"Kim","year":"2022","journal-title":"Sci. Rep."},{"issue":"10","key":"10.1016\/j.jmbbm.2023.105843_b23","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pcbi.1004535","article-title":"Cell invasion dynamics into a three dimensional extracellular matrix fibre network","volume":"11","author":"Kim","year":"2015","journal-title":"PLoS Comput. Biol."},{"key":"10.1016\/j.jmbbm.2023.105843_b24","series-title":"Biomedical Implications from Mathematical Models for the Simulation of Dermal Wound Healing","author":"Koppenol","year":"2017"},{"issue":"4","key":"10.1016\/j.jmbbm.2023.105843_b25","doi-asserted-by":"crossref","first-page":"1753","DOI":"10.1137\/130927619","article-title":"Optimal a priori error estimates for an elliptic problem with Dirac right-hand side","volume":"52","author":"K\u00f6ppl","year":"2014","journal-title":"SIAM J. Numer. Anal."},{"issue":"5","key":"10.1016\/j.jmbbm.2023.105843_b26","doi-asserted-by":"crossref","first-page":"1767","DOI":"10.1007\/s10237-021-01475-z","article-title":"Rapid, quantitative prediction of tumor invasiveness in non-melanoma skin cancers using mechanobiology-based assay","volume":"20","author":"Kortam","year":"2021","journal-title":"Biomech. Model. Mechanobiol."},{"issue":"1","key":"10.1016\/j.jmbbm.2023.105843_b27","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1146\/annurev-fluid-120710-101102","article-title":"The fluid mechanics of cancer and its therapy","volume":"45","author":"Koumoutsakos","year":"2013","journal-title":"Annu. Rev. Fluid Mech."},{"issue":"1779","key":"10.1016\/j.jmbbm.2023.105843_b28","doi-asserted-by":"crossref","DOI":"10.1098\/rstb.2018.0225","article-title":"Cell migration through three-dimensional confining pores: speed accelerations by deformation and recoil of the nucleus","volume":"374","author":"Krause","year":"2019","journal-title":"Philos. Trans. R. Soc. Lond. B Biol. Sci."},{"issue":"6","key":"10.1016\/j.jmbbm.2023.105843_b29","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1016\/j.tcb.2016.02.002","article-title":"Front\u2013rear polarization by mechanical cues: From single cells to tissues","volume":"26","author":"Ladoux","year":"2016","journal-title":"Trends Cell Biol."},{"issue":"5","key":"10.1016\/j.jmbbm.2023.105843_b30","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1007\/s10237-010-0271-1","article-title":"Modeling cell entry into a micro-channel","volume":"10","author":"Leong","year":"2010","journal-title":"Biomech. Model. Mechanobiol."},{"key":"10.1016\/j.jmbbm.2023.105843_b31","series-title":"Cell Polarity 1","first-page":"115","article-title":"Front-to-rear polarity in migrating cells","author":"Llense","year":"2015"},{"issue":"11","key":"10.1016\/j.jmbbm.2023.105843_b32","doi-asserted-by":"crossref","first-page":"1374","DOI":"10.1039\/c3ib40128f","article-title":"A serial micropipette microfluidic device with applications to cancer cell repeated deformation studies","volume":"5","author":"Mak","year":"2013","journal-title":"Integr. Biol."},{"issue":"3","key":"10.1016\/j.jmbbm.2023.105843_b33","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1039\/C2LC41117B","article-title":"Elucidating mechanical transition effects of invading cancer cells with a subnucleus-scaled microfluidic serial dimensional modulation device","volume":"13","author":"Mak","year":"2013","journal-title":"Lab Chip"},{"issue":"3","key":"10.1016\/j.jmbbm.2023.105843_b34","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1007\/s10237-016-0864-4","article-title":"Metastatic breast cancer cells adhere strongly on varying stiffness substrates, initially without adjusting their morphology","volume":"16","author":"Massalha","year":"2016","journal-title":"Biomech. Model. Mechanobiol."},{"issue":"12","key":"10.1016\/j.jmbbm.2023.105843_b35","doi-asserted-by":"crossref","first-page":"2846","DOI":"10.1007\/s10439-020-02547-4","article-title":"Rapid cancer diagnosis and early prognosis of metastatic risk based on mechanical invasiveness of sampled cells","volume":"48","author":"Merkher","year":"2020","journal-title":"Ann. Biomed. Eng."},{"issue":"6","key":"10.1016\/j.jmbbm.2023.105843_b36","doi-asserted-by":"crossref","first-page":"1399","DOI":"10.1007\/s10439-017-1814-8","article-title":"Proximity of metastatic cells enhances their mechanobiological invasiveness","volume":"45","author":"Merkher","year":"2017","journal-title":"Ann. Biomed. Eng."},{"issue":"3","key":"10.1016\/j.jmbbm.2023.105843_b37","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/S0092-8674(00)81281-7","article-title":"Actin-based cell motility and cell locomotion","volume":"84","author":"Mitchison","year":"1996","journal-title":"Cell"},{"issue":"17","key":"10.1016\/j.jmbbm.2023.105843_b38","doi-asserted-by":"crossref","first-page":"R762","DOI":"10.1016\/j.cub.2009.06.053","article-title":"The shape of motile cells","volume":"19","author":"Mogilner","year":"2009","journal-title":"Curr. Biol."},{"issue":"17","key":"10.1016\/j.jmbbm.2023.105843_b39","doi-asserted-by":"crossref","first-page":"R790","DOI":"10.1016\/j.cub.2009.07.029","article-title":"Biology and physics of cell shape changes in development","volume":"19","author":"Paluch","year":"2009","journal-title":"Curr. Biol."},{"issue":"2","key":"10.1016\/j.jmbbm.2023.105843_b40","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1038\/nrc.2016.123","article-title":"Cancer cell motility: lessons from migration in confined spaces","volume":"17","author":"Paul","year":"2016","journal-title":"Nat. Rev. Cancer"},{"issue":"3","key":"10.1016\/j.jmbbm.2023.105843_b41","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1007\/s10237-022-01568-3","article-title":"Comparison between a phenomenological approach and a morphoelasticity approach regarding the displacement of extracellular matrix","volume":"21","author":"Peng","year":"2022","journal-title":"Biomech. Model. Mechanobiol."},{"issue":"6","key":"10.1016\/j.jmbbm.2023.105843_b42","doi-asserted-by":"crossref","first-page":"2525","DOI":"10.1007\/s10237-020-01354-z","article-title":"Agent-based modelling and parameter sensitivity analysis with a finite-element method for skin contraction","volume":"19","author":"Peng","year":"2020","journal-title":"Biomech. Model. Mechanobiol."},{"key":"10.1016\/j.jmbbm.2023.105843_b43","doi-asserted-by":"crossref","DOI":"10.1016\/j.cam.2021.113892","article-title":"Numerical methods to compute stresses and displacements from cellular forces: Application to the contraction of tissue","volume":"404","author":"Peng","year":"2022","journal-title":"J. Comput. Appl. Math."},{"key":"10.1016\/j.jmbbm.2023.105843_b44","doi-asserted-by":"crossref","DOI":"10.1007\/s10237-021-01456-2","article-title":"A formalism for modelling traction forces and cell shape evolution during cell migration in various biomedical processes","author":"Peng","year":"2021","journal-title":"Biomech. Model. Mechanobiol."},{"key":"10.1016\/j.jmbbm.2023.105843_b45","series-title":"Handbook of Contact Mechanics: Exact Solutions of Axisymmetric Contact Problems","author":"Popov","year":"2019"},{"key":"10.1016\/j.jmbbm.2023.105843_b46","series-title":"Methods of Mathematical Oncology: Fusion of Mathematics and Biology","first-page":"124","article-title":"Multi-level mathematical models for cell migration in confined environments","author":"Preziosi","year":"2021"},{"key":"10.1016\/j.jmbbm.2023.105843_b47","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.coisb.2017.03.005","article-title":"Mechanisms of cell polarization","volume":"3","author":"Rappel","year":"2017","journal-title":"Curr. Opin. Syst. Biol."},{"key":"10.1016\/j.jmbbm.2023.105843_b48","series-title":"Advances in Experimental Medicine and Biology","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1007\/978-3-319-42023-3_5","article-title":"Circulating tumor cells: When a solid tumor meets a fluid microenvironment","author":"Rejniak","year":"2016"},{"issue":"12","key":"10.1016\/j.jmbbm.2023.105843_b49","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pcbi.1007459","article-title":"From energy to cellular forces in the cellular potts model: An algorithmic approach","volume":"15","author":"Rens","year":"2019","journal-title":"PLoS Comput. Biol."},{"issue":"8","key":"10.1016\/j.jmbbm.2023.105843_b50","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1038\/nrc3078","article-title":"Chemotaxis in cancer","volume":"11","author":"Roussos","year":"2011","journal-title":"Nat. Rev. Cancer"},{"issue":"7","key":"10.1016\/j.jmbbm.2023.105843_b51","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pcbi.1007213","article-title":"A computational framework for the morpho-elastic development of molluskan shells by surface and volume growth","volume":"15","author":"Rudraraju","year":"2019","journal-title":"PLoS Comput. Biol."},{"issue":"3","key":"10.1016\/j.jmbbm.2023.105843_b52","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1093\/imammb\/dqab009","article-title":"A mathematical framework for modelling 3D cell motility: applications to glioblastoma cell migration","volume":"38","author":"Scott","year":"2021","journal-title":"Math. Med. Biol."},{"issue":"2","key":"10.1016\/j.jmbbm.2023.105843_b53","doi-asserted-by":"crossref","first-page":"912","DOI":"10.1529\/biophysj.105.061150","article-title":"Cell motility as persistent random motion: Theories from experiments","volume":"89","author":"Selmeczi","year":"2005","journal-title":"Biophys. J."},{"key":"10.1016\/j.jmbbm.2023.105843_b54","unstructured":"Shapiro, S.S., 1990. How to Test Normality and Other Distributional Assumptions. Technical Report."},{"issue":"40","key":"10.1016\/j.jmbbm.2023.105843_b55","doi-asserted-by":"crossref","first-page":"14448","DOI":"10.1073\/pnas.1412197111","article-title":"Cellular memory in eukaryotic chemotaxis","volume":"111","author":"Skoge","year":"2014","journal-title":"Proc. Natl. Acad. Sci."},{"issue":"15","key":"10.1016\/j.jmbbm.2023.105843_b56","doi-asserted-by":"crossref","first-page":"5075","DOI":"10.1158\/0008-5472.CAN-11-0247","article-title":"Mechanical stiffness grades metastatic potential in patient tumor cells and in cancer cell lines","volume":"71","author":"Swaminathan","year":"2011","journal-title":"Cancer Res."},{"issue":"7","key":"10.1016\/j.jmbbm.2023.105843_b57","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0002648","article-title":"Functional analysis of spontaneous cell movement under different physiological conditions","volume":"3","author":"Takagi","year":"2008","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/j.jmbbm.2023.105843_b58","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.jbiomech.2004.11.006","article-title":"Determination of the Poisson's ratio of the cell: recovery properties of chondrocytes after release from complete micropipette aspiration","volume":"39","author":"Trickey","year":"2006","journal-title":"J. Biomech."},{"key":"10.1016\/j.jmbbm.2023.105843_b59","article-title":"Computational modeling reveals a vital role for proximity-driven additive and synergistic cell-cell interactions in increasing cancer invasiveness","author":"Tulchinsky","year":"2022","journal-title":"Acta Biomater."},{"issue":"1","key":"10.1016\/j.jmbbm.2023.105843_b60","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/S0960-9822(99)80042-6","article-title":"Self-polarization and directional motility of cytoplasm","volume":"9","author":"Verkhovsky","year":"1999","journal-title":"Curr. Biol."},{"issue":"2","key":"10.1016\/j.jmbbm.2023.105843_b61","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1007\/s10237-012-0400-0","article-title":"A phenomenological model for chemico-mechanically induced cell shape changes during migration and cell\u2013cell contacts","volume":"12","author":"Vermolen","year":"2012","journal-title":"Biomech. Model. Mechanobiol."},{"issue":"4","key":"10.1016\/j.jmbbm.2023.105843_b62","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a002980","article-title":"The signaling mechanisms underlying cell polarity and chemotaxis","volume":"1","author":"Wang","year":"2009","journal-title":"Cold Spring Harb. Perspect. Biol."},{"key":"10.1016\/j.jmbbm.2023.105843_b63","series-title":"An introduction to statistical analysis in research","author":"Weaver","year":"2017"},{"issue":"1","key":"10.1016\/j.jmbbm.2023.105843_b64","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1002\/cm.20041","article-title":"Effects of substrate stiffness on cell morphology, cytoskeletal structure, and adhesion","volume":"60","author":"Yeung","year":"2004","journal-title":"Cell Motil. Cytoskeleton"},{"issue":"6","key":"10.1016\/j.jmbbm.2023.105843_b65","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1038\/nphys1613","article-title":"Optimal matrix rigidity for stress-fibre polarization in stem cells","volume":"6","author":"Zemel","year":"2010","journal-title":"Nat. Phys."},{"issue":"1","key":"10.1016\/j.jmbbm.2023.105843_b66","doi-asserted-by":"crossref","first-page":"6529","DOI":"10.1038\/s41598-021-85640-5","article-title":"Morphodynamic signatures of MDA-MB-231 single cells and cell doublets undergoing invasion in confined microenvironments","volume":"11","author":"Zhang","year":"2021","journal-title":"Sci. Rep."},{"issue":"129","key":"10.1016\/j.jmbbm.2023.105843_b67","doi-asserted-by":"crossref","DOI":"10.1098\/rsif.2016.0959","article-title":"Dynamic cellular finite-element method for modelling large-scale cell migration and proliferation under the control of mechanical and biochemical cues: a study of re-epithelialization","volume":"14","author":"Zhao","year":"2017","journal-title":"J. R. Soc. Interface"},{"issue":"5","key":"10.1016\/j.jmbbm.2023.105843_b68","doi-asserted-by":"crossref","first-page":"1781","DOI":"10.1007\/s10237-020-01308-5","article-title":"Cell\u2013substrate mechanics guide collective cell migration through intercellular adhesion: a dynamic finite element cellular model","volume":"19","author":"Zhao","year":"2020","journal-title":"Biomech. Model. Mechanobiol."}],"container-title":["Journal of the Mechanical Behavior of Biomedical Materials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1751616123001960?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1751616123001960?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T22:49:16Z","timestamp":1761691756000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1751616123001960"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6]]},"references-count":68,"alternative-id":["S1751616123001960"],"URL":"https:\/\/doi.org\/10.1016\/j.jmbbm.2023.105843","relation":{},"ISSN":["1751-6161"],"issn-type":[{"value":"1751-6161","type":"print"}],"subject":[],"published":{"date-parts":[[2023,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Physical confinement and cell proximity increase cell migration rates and invasiveness: A mathematical model of cancer cell invasion through flexible channels","name":"articletitle","label":"Article Title"},{"value":"Journal of the Mechanical Behavior of Biomedical Materials","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jmbbm.2023.105843","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Author(s). Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"105843"}}