{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,25]],"date-time":"2026-10-25T04:03:15Z","timestamp":1792900995552,"version":"4.5.0"},"reference-count":105,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the Mechanical Behavior of Biomedical Materials"],"published-print":{"date-parts":[[2023,9]]},"DOI":"10.1016\/j.jmbbm.2023.105974","type":"journal-article","created":{"date-parts":[[2023,6,25]],"date-time":"2023-06-25T05:41:23Z","timestamp":1687671683000},"page":"105974","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":40,"special_numbering":"C","title":["An overview of the tribological and mechanical properties of PEEK and CFR-PEEK for use in total joint replacements"],"prefix":"10.1016","volume":"145","author":[{"given":"Sofia","family":"Arevalo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claire","family":"Arthurs","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria I. Echeverria","family":"Molina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa","family":"Pruitt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anurag","family":"Roy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jmbbm.2023.105974_b1","doi-asserted-by":"crossref","first-page":"3689","DOI":"10.1002\/jbm.a.35480","article-title":"Biomechanical and bioactivity concepts of polyetheretherketone composites for use in orthopedic implants - a review","volume":"103","author":"Abdullah","year":"2015","journal-title":"J. Biomed. Mater. Res. A"},{"issue":"5","key":"10.1016\/j.jmbbm.2023.105974_b2","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1002\/hed.23370","article-title":"Craniofacial bone reconstruction with bioactive fiber-reinforced composite implant","volume":"36","author":"Aitasalo","year":"2014","journal-title":"Head Neck"},{"key":"10.1016\/j.jmbbm.2023.105974_b3","series-title":"Standard Practice for Direct Contact Cell Culture Evaluation of Materials for Medical Devices","author":"American Society for Testing and Materials","year":"2012"},{"key":"10.1016\/j.jmbbm.2023.105974_b4","article-title":"Methods for detecting carcinogens and mutagens with the Salmonella\/mammalian-microsome mutagenicity test","volume":"31","author":"Ames","year":"1975","journal-title":"Mutat. Res.;(Netherlands)"},{"key":"10.1016\/j.jmbbm.2023.105974_b5","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.jmbbm.2015.08.026","article-title":"Effect of processing, sterilization and crosslinking on UHMWPE fatigue fracture and fatigue wear mechanisms in joint arthroplasty","volume":"53","author":"Ansari","year":"2016","journal-title":"J. Mech. Behav. Biomed. Mater."},{"key":"10.1016\/j.jmbbm.2023.105974_b6","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1097\/00003086-200010000-00003","article-title":"Alternate bearing surfaces in total joint arthroplasty: biologic considerations","volume":"379","author":"Archibeck","year":"2000","journal-title":"Clin. Orthop. Relat. Res."},{"key":"10.1016\/j.jmbbm.2023.105974_b7","doi-asserted-by":"crossref","DOI":"10.1016\/j.jmbbm.2020.104008","article-title":"Nanomechanical analysis of medical grade PEEK and carbon fiber-reinforced PEEK composites","volume":"111","author":"Arevalo","year":"2020","journal-title":"J. Mech. Behav. Biomed. Mater."},{"issue":"3\u20134","key":"10.1016\/j.jmbbm.2023.105974_b8","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1053\/j.sart.2006.09.002","article-title":"Ceramic materials in total joint arthroplasty","volume":"17","author":"Bal","year":"2006","journal-title":"Sem. Arthroplasty"},{"issue":"1","key":"10.1016\/j.jmbbm.2023.105974_b9","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/S1935-9810(07)70045-2","article-title":"Nubac disc arthroplasty: preclinical studies and preliminary safety and efficacy evaluations","volume":"1","author":"Bao","year":"2007","journal-title":"SAS J."},{"key":"10.1016\/j.jmbbm.2023.105974_b10","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1016\/0032-3861(83)90144-1","article-title":"The morphology of poly(aryl-ether-ether-ketone)","volume":"24","author":"Blundell","year":"1983","journal-title":"Polymer"},{"key":"10.1016\/j.jmbbm.2023.105974_b11","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1016\/j.jmbbm.2018.10.033","article-title":"Effect of carbon fiber type on monotonic and fatigue properties of orthopedic grade PEEK","volume":"90","author":"Bonnheim","year":"2019","journal-title":"J. Mech. Behav. Biomed. Mater."},{"key":"10.1016\/j.jmbbm.2023.105974_b12","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.jmbbm.2016.06.005","article-title":"Influence of contact pressure, cross-shear and counterface material on the wear of PEEK and CFR-PEEK for orthopaedic applications","volume":"63","author":"Brockett","year":"2016","journal-title":"J. Mech. Behav. Biomed. Mater."},{"key":"10.1016\/j.jmbbm.2023.105974_b13","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.wear.2016.12.010","article-title":"PEEK and CFR-PEEK as alternative bearing materials to UHMWPE in a fixed bearing total knee replacement: An experimental wear study","volume":"374\u2013375","author":"Brockett","year":"2017","journal-title":"Wear"},{"issue":"6","key":"10.1016\/j.jmbbm.2023.105974_b14","doi-asserted-by":"crossref","first-page":"1459","DOI":"10.1002\/jbm.b.32664","article-title":"Wear of ceramic-on-carbon fiber-reinforced poly-ether ether ketone hip replacements","volume":"100B","author":"Brockett","year":"2012","journal-title":"J. Biomed. Mater. Res. B Appl. Biomater."},{"issue":"2","key":"10.1016\/j.jmbbm.2023.105974_b15","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1002\/jbm.b.34136","article-title":"Wear properties of poly-ether-ether-ketone bearing combinations under zero and cross shear kinematics in total knee arthroplasty","volume":"107","author":"Chamberlain","year":"2019","journal-title":"J. Biomed. Mater. Res. B Appl. Biomater."},{"key":"10.1016\/j.jmbbm.2023.105974_b16","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1097\/00003086-199209000-00004","article-title":"Role of ceramic implants. Design and clinical issues with total hip prosthetic ceramic-to-ceramic bearings","volume":"282","author":"Clarke","year":"1992","journal-title":"Clin. Orthop. Relat. Res."},{"issue":"3","key":"10.1016\/j.jmbbm.2023.105974_b17","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/0010-4361(83)90012-5","article-title":"Environmental resistance of carbon fibre-reinforced polyether etherketone","volume":"14","author":"Cogswell","year":"1983","journal-title":"Composites"},{"issue":"3","key":"10.1016\/j.jmbbm.2023.105974_b18","first-page":"176","article-title":"Preliminary evaluation of titanium-coated PEEK dental implants.","volume":"21","author":"Cook","year":"1995","journal-title":"J. Oral Implantol."},{"issue":"6","key":"10.1016\/j.jmbbm.2023.105974_b19","doi-asserted-by":"crossref","first-page":"1264","DOI":"10.3390\/ma13061264","article-title":"Third body wear of UHMWPE-on-PEEK-OPTIMA\u2122","volume":"13","author":"Cowie","year":"2020","journal-title":"Materials"},{"issue":"3","key":"10.1016\/j.jmbbm.2023.105974_b20","doi-asserted-by":"crossref","first-page":"336","DOI":"10.3171\/2013.5.SPINE13166","article-title":"Epidural application of spinal instrumentation particulate wear debris: a comprehensive evaluation of neurotoxicity using an in vivo animal model","volume":"19","author":"Cunningham","year":"2013","journal-title":"J. Neurosurg. Spine"},{"key":"10.1016\/j.jmbbm.2023.105974_b21","doi-asserted-by":"crossref","DOI":"10.1016\/j.jbiomech.2021.110270","article-title":"Decreased stress shielding with a PEEK femoral total knee prosthesis measured in validated computational models","volume":"118","author":"de Ruiter","year":"2021","journal-title":"J. Biomech."},{"key":"10.1016\/j.jmbbm.2023.105974_b22","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1016\/j.compstruct.2016.11.070","article-title":"Dynamic mechanical properties of carbon fibre-reinforced PEEK composites in simulated body-fluid","volume":"161","author":"Dworak","year":"2017","journal-title":"Compos. Struct."},{"issue":"3","key":"10.1016\/j.jmbbm.2023.105974_b23","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1177\/0954411915576353","article-title":"Wear of PEEK-OPTIMA\u00ae and PEEK-OPTIMA\u00ae-Wear Performance articulating against highly cross-linked polyethylene","volume":"229","author":"East","year":"2015","journal-title":"Proc. Inst. Mech. Eng. H"},{"issue":"6","key":"10.1016\/j.jmbbm.2023.105974_b24","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1177\/0954411914538783","article-title":"The influence of nominal stress on wear factors of carbon fibre\u2013reinforced polyetheretherketone (PEEK-optima\u00ae Wear Performance) against zirconia toughened alumina (Biolox\u00aedelta ceramic)","volume":"228","author":"Evans","year":"2014","journal-title":"Proc. Inst. Mech. Eng. H"},{"key":"10.1016\/j.jmbbm.2023.105974_b25","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1016\/S0043-1648(99)00022-8","article-title":"On the friction and wear behaviour of PAN- and pitch-carbon fiber reinforced PEEK composites","volume":"225\u2013229","author":"Fl\u00f6ck","year":"1999","journal-title":"Wear"},{"issue":"1","key":"10.1016\/j.jmbbm.2023.105974_b26","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1002\/jor.1100120111","article-title":"In vivo inflammatory response to polymethylmethacrylate particulate debris: effect of size, morphology, and surface area","volume":"12","author":"Gelb","year":"1994","journal-title":"J. Orthop. Res."},{"issue":"8","key":"10.1016\/j.jmbbm.2023.105974_b27","doi-asserted-by":"crossref","first-page":"1550","DOI":"10.1016\/j.biomaterials.2005.09.010","article-title":"Fatigue crack propagation resistance of virgin and highly crosslinked, thermally treated ultra-high molecular weight polyethylene","volume":"27","author":"Gencur","year":"2006","journal-title":"Biomaterials"},{"issue":"5","key":"10.1016\/j.jmbbm.2023.105974_b28","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1002\/jor.1100120515","article-title":"Response of three murine macrophage populations to particulate debris: bone resorption in organ cultures","volume":"12","author":"Glant","year":"1994","journal-title":"J. Orthop. Res."},{"issue":"5","key":"10.1016\/j.jmbbm.2023.105974_b29","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1002\/1097-4636(200009)53:5<490::AID-JBM7>3.0.CO;2-7","article-title":"Effect of size and dose on bone resorption activity of macrophages by in vitro clinically relevant ultra high molecular weight polyethylene particles","volume":"53","author":"Green","year":"2000","journal-title":"J. Biomed. Mater. Res."},{"issue":"24","key":"10.1016\/j.jmbbm.2023.105974_b30","doi-asserted-by":"crossref","first-page":"2297","DOI":"10.1016\/S0142-9612(98)00140-9","article-title":"Polyethylene particles of a \u2018critical size\u2019are necessary for the induction of cytokines by macrophages in vitro","volume":"19","author":"Green","year":"1998","journal-title":"Biomaterials"},{"key":"10.1016\/j.jmbbm.2023.105974_b31","series-title":"Orthopaedic Proceedings, Vol. 96, No. SUPP_11","first-page":"223","article-title":"Evaluation of carbon-fibre-reinforced PEEK as material for intervertebral disc replacement","author":"Grupp","year":"2014"},{"issue":"9","key":"10.1016\/j.jmbbm.2023.105974_b32","doi-asserted-by":"crossref","first-page":"3601","DOI":"10.1016\/j.actbio.2010.04.003","article-title":"Biotribology of alternative bearing materials for unicompartmental knee arthroplasty","volume":"6","author":"Grupp","year":"2010","journal-title":"Acta Biomater."},{"issue":"2","key":"10.1016\/j.jmbbm.2023.105974_b33","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1002\/jbm.b.31974","article-title":"Macrophage reactivity to different polymers demonstrates particle size-and material-specific reactivity: PEEK-optima\u00ae particles versus UHMWPE particles in the submicron, micron, and 10 micron size ranges","volume":"100","author":"Hallab","year":"2012","journal-title":"J. Biomed. Mater. Res. B Appl. Biomater."},{"issue":"2","key":"10.1016\/j.jmbbm.2023.105974_b34","doi-asserted-by":"crossref","first-page":"758","DOI":"10.1002\/jbm.b.10068","article-title":"Biological response to wear debris generated in carbon based composites as potential bearing surfaces for artificial hip joints.","volume":"67","author":"Howling","year":"2003","journal-title":"J. Biomed. Mater. Res. B Appl. Biomater."},{"issue":"2","key":"10.1016\/j.jmbbm.2023.105974_b35","first-page":"177","article-title":"Comparison of the biological activity of grade GUR 1120 and GUR 415HP UHMWPE wear debris","volume":"12","author":"Ingram","year":"2002","journal-title":"Biomed. Mater. Eng."},{"issue":"2","key":"10.1016\/j.jmbbm.2023.105974_b36","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1002\/jbm.820260202","article-title":"Biological response to chopped-carbon-fiber-reinforced peek","volume":"26","author":"Jockisch","year":"1992","journal-title":"J. Biomed. Mater. Res."},{"issue":"3","key":"10.1016\/j.jmbbm.2023.105974_b37","first-page":"141","article-title":"The wear of two orthopaedic biopolymers against each other","volume":"3","author":"Joyce","year":"2005","journal-title":"J. Appl. Biomater. Biomech."},{"key":"10.1016\/j.jmbbm.2023.105974_b38","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.jmbbm.2019.05.022","article-title":"Wear behaviour of CFR PEEK articulated against CoCr under varying contact stresses: Low wear of CFR PEEK negated by wear of the CoCr counterface","volume":"97","author":"Kandemir","year":"2019","journal-title":"J. Mech. Behav. Biomed. Mater."},{"issue":"8","key":"10.1016\/j.jmbbm.2023.105974_b39","doi-asserted-by":"crossref","first-page":"1749","DOI":"10.1016\/S0142-9612(01)00300-3","article-title":"Polyetheretherketone\u2014cytotoxicity and mutagenicity in vitro","volume":"23","author":"Katzer","year":"2002","journal-title":"Biomaterials"},{"key":"10.1016\/j.jmbbm.2023.105974_b40","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1016\/S0021-9290(99)00041-X","article-title":"Correlation between pre-operative periprosthetic bone density and post-operative bone loss in THA can be explained by strain-adaptive remodeling","volume":"32","author":"Kerner","year":"1999","journal-title":"J. Biomech."},{"issue":"4","key":"10.1016\/j.jmbbm.2023.105974_b41","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1016\/j.ajoms.2013.04.006","article-title":"Severe infectious complications after PEEK-derived implant placement: report of three cases","volume":"26","author":"Khonsari","year":"2014","journal-title":"J. Oral Maxillofac. Surg. Med. Pathol."},{"key":"10.1016\/j.jmbbm.2023.105974_b42","series-title":"Advanced Engineering Materials III","first-page":"164","article-title":"Mechanical properties of carbon\/PEEK composites according to the fiber ply orientation and sizing removal of carbon fiber for artificial hip joint","volume":"750","author":"Kim","year":"2013"},{"key":"10.1016\/j.jmbbm.2023.105974_b43","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.msec.2019.02.082","article-title":"Total knee arthroplasty application of polyetheretherketone and carbon-fiber-reinforced polyetheretherketone: A review","volume":"100","author":"Koh","year":"2019","journal-title":"Mater. Sci. Eng. C"},{"issue":"17","key":"10.1016\/j.jmbbm.2023.105974_b44","doi-asserted-by":"crossref","first-page":"1386","DOI":"10.2106\/JBJS.N.01141","article-title":"Prevalence of total hip and knee replacement in the United States","volume":"97","author":"Kremers","year":"2015","journal-title":"J. Bone Joint Surg. [Am]"},{"key":"10.1016\/j.jmbbm.2023.105974_b45","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/0032-3861(86)90145-X","article-title":"Crystallization and morphology of poly(aryl-ether-ether-ketone)","volume":"27","author":"Kumar","year":"1986","journal-title":"Polymer"},{"issue":"1","key":"10.1016\/j.jmbbm.2023.105974_b46","doi-asserted-by":"crossref","DOI":"10.3390\/bioengineering5010018","article-title":"Effects of sterilization cycles on PEEK for medical device application","volume":"5","author":"Kumar","year":"2018","journal-title":"Bioengineering"},{"key":"10.1016\/j.jmbbm.2023.105974_b47","series-title":"UHMWPE Biomaterials Handbook: Ultra High Molecular Weight Polyethylene in Total Joint Replacement and Medical Devices","author":"Kurtz","year":"2009"},{"key":"10.1016\/j.jmbbm.2023.105974_b48","series-title":"An Overview of PEEK Biomaterials","first-page":"1","author":"Kurtz","year":"2012"},{"key":"10.1016\/j.jmbbm.2023.105974_b49","series-title":"Handbook of Polymer Applications in Medicine and Medical Devices","first-page":"231","article-title":"Applications of polyaryletheretherketone in spinal implants: Fusion and motion preservation","author":"Kurtz","year":"2012"},{"issue":"32","key":"10.1016\/j.jmbbm.2023.105974_b50","doi-asserted-by":"crossref","first-page":"4845","DOI":"10.1016\/j.biomaterials.2007.07.013","article-title":"PEEK biomaterials in trauma, orthopedic, and spinal implants","volume":"28","author":"Kurtz","year":"2007","journal-title":"Biomaterials"},{"issue":"7","key":"10.1016\/j.jmbbm.2023.105974_b51","first-page":"1487","article-title":"Prevalence of primary and revision total hip and knee arthroplasty in the United States from 1990 through 2002","volume":"87","author":"Kurtz","year":"2005","journal-title":"J. Bone Joint. Surg."},{"key":"10.1016\/j.jmbbm.2023.105974_b52","doi-asserted-by":"crossref","first-page":"2606","DOI":"10.1007\/s11999-009-0834-6","article-title":"Future Young patient demand for primary and revision joint replacement: National projections from 2010 to 2030","author":"Kurtz","year":"2009","journal-title":"Clin. Orthop."},{"issue":"4","key":"10.1016\/j.jmbbm.2023.105974_b53","doi-asserted-by":"crossref","first-page":"1729","DOI":"10.1007\/s10856-007-3256-6","article-title":"Pre-clinical studies to validate the MITCH PCR\u2122 Cup: a flexible and anatomically shaped acetabular component with novel bearing characteristics","volume":"19","author":"Latif","year":"2008","journal-title":"J. Mater. Sci., Mater. Med."},{"key":"10.1016\/j.jmbbm.2023.105974_b54","doi-asserted-by":"crossref","DOI":"10.4137\/CMAMD.S20354","article-title":"The use of carbon-fiber-reinforced (CFR) PEEK material in orthopedic implants: a systematic review","volume":"8","author":"Li","year":"2015","journal-title":"Clin. Med. Insights Arthritis Musculoskelet. Disord."},{"issue":"12","key":"10.1016\/j.jmbbm.2023.105974_b55","doi-asserted-by":"crossref","first-page":"2858","DOI":"10.3390\/polym12122858","article-title":"Polyetheretherketone and its composites for bone replacement and regeneration","volume":"12","author":"Liao","year":"2020","journal-title":"Polymers"},{"issue":"1","key":"10.1016\/j.jmbbm.2023.105974_b56","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1007\/s10856-013-5037-8","article-title":"Elevated cytokine expression of different PEEK wear particles compared to UHMWPE in vivo","volume":"25","author":"Lorber","year":"2014","journal-title":"J. Mater. Sci., Mater. Med."},{"issue":"4","key":"10.1016\/j.jmbbm.2023.105974_b57","first-page":"450","article-title":"Bioactive polyetheretherketone implant composites for hard tissue","volume":"29","author":"Lvhua","year":"2017","journal-title":"Prog. Chem."},{"key":"10.1016\/j.jmbbm.2023.105974_b58","doi-asserted-by":"crossref","DOI":"10.1016\/j.arabjc.2020.102977","article-title":"PEEK (polyether-ether-ketone) and its composite materials in orthopedic implantation","author":"Ma","year":"2021","journal-title":"Arab. J. Chem."},{"key":"10.1016\/j.jmbbm.2023.105974_b59","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1097\/01.blo.0000150309.48474.8b","article-title":"Metal-on-metal total hip arthroplasty: The concerns.","volume":"429","author":"MacDonald","year":"2004","journal-title":"Clin. Orthop. Relat. Res."},{"issue":"2","key":"10.1016\/j.jmbbm.2023.105974_b60","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1002\/1097-4636(200011)52:2<296::AID-JBM8>3.0.CO;2-9","article-title":"Evaluation of the response of primary human peripheral blood mononuclear phagocytes to challenge with in vitro generated clinically relevant UHMWPE particles of known size and dose","volume":"52","author":"Matthews","year":"2000","journal-title":"J. Biomed. Mater. Res."},{"issue":"3, 4","key":"10.1016\/j.jmbbm.2023.105974_b61","first-page":"229","article-title":"Comparison of the response of primary murine peritoneal macrophages and the U937 human histiocytic cell line to challenge with in vitro generated clinically relevant UHMWPE particles","volume":"10","author":"Matthews","year":"2000","journal-title":"Biomed. Mater. Eng."},{"key":"10.1016\/j.jmbbm.2023.105974_b62","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1016\/j.matlet.2016.09.005","article-title":"Mechanical and biological behavior of biomedical PEEK matrix composites: A focused review","volume":"185","author":"Monich","year":"2016","journal-title":"Mater. Lett."},{"issue":"13","key":"10.1016\/j.jmbbm.2023.105974_b63","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1016\/0142-9612(95)94906-2","article-title":"In vitro biocompatibility testing of polymers for orthopaedic implants using cultured fibroblasts and osteoblasts","volume":"16","author":"Morrison","year":"1995","journal-title":"Biomaterials"},{"issue":"2","key":"10.1016\/j.jmbbm.2023.105974_b64","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1002\/jbm.a.31310","article-title":"Amorphous and crystalline polyetheretherketone: Mechanical properties and tissue reactions during a 3-year follow-up","volume":"84","author":"Nieminen","year":"2008","journal-title":"J. Biomed. Mater. Res. A"},{"key":"10.1016\/j.jmbbm.2023.105974_b65","first-page":"P13","article-title":"Elemental and histological analysis of a retrieved peek composite-ceramic bearing couple, 28 months after implantation","volume":"18","author":"Pace","year":"2005","journal-title":"Trans. Int. Soc. Technol. Arthroplas. (ISTA)"},{"issue":"1","key":"10.1016\/j.jmbbm.2023.105974_b66","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.arth.2006.07.012","article-title":"Technical and histologic analysis of a retrieved carbon fiber\u2013reinforced poly-ether-ether-ketone composite alumina-bearing liner 28 months after implantation","volume":"23","author":"Pace","year":"2008","journal-title":"J. Arthroplast."},{"key":"10.1016\/j.jmbbm.2023.105974_b67","first-page":"2","article-title":"Primary total hip arthroplasty with carbon fibre reinforced poly-ether-ether-ketone composite acetabular cup component 36 months results","volume":"18","author":"Pace","year":"2005","journal-title":"Trans. Int. Soc. Technol. Arthroplasty (ISTA)"},{"issue":"2","key":"10.1016\/j.jmbbm.2023.105974_b68","first-page":"132","article-title":"Clinical trial of a new CF-PEEK acetabular insert in hip arthroplasty: P080","volume":"14","author":"Pace","year":"2004","journal-title":"Hip Int."},{"issue":"5","key":"10.1016\/j.jmbbm.2023.105974_b69","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1002\/jbm.820280514","article-title":"In vivo induction of macrophage Ia antigen (MHC class II) expression by biomedical polymers in the cage implant system","volume":"28","author":"Petillo","year":"1994","journal-title":"J. Biomed. Mater. Res."},{"key":"10.1016\/j.jmbbm.2023.105974_b70","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1007\/s00701-015-2363-2","article-title":"Paediatric cranial defect reconstruction using bioactive fibre-reinforced composite implant: early outcomes","volume":"157","author":"Piitulainen","year":"2015","journal-title":"Acta Neurochir."},{"key":"10.1016\/j.jmbbm.2023.105974_b71","series-title":"Alternative Bearing Surfaces in Total Joint Replacement","article-title":"Characterization of carbon fiber-reinforced PEEK composite for use as a bearing material in total hip replacements","author":"Polineni","year":"1998"},{"key":"10.1016\/j.jmbbm.2023.105974_b72","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.jmbbm.2015.10.030","article-title":"A glass fiber-reinforced composite\u2013bioactive glass cranioplasty implant: a case study of an early development stage implant removed due to a late infection","volume":"55","author":"Posti","year":"2016","journal-title":"J. Mech. Behav. Biomed. Mater."},{"key":"10.1016\/j.jmbbm.2023.105974_b73","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/j.jmbbm.2018.09.040","article-title":"Mechanical properties and cytotoxicity of hierarchical carbon fiber-reinforced poly (ether-ether-ketone) composites used as implant materials","volume":"89","author":"Qin","year":"2019","journal-title":"J. Mech. Behav. Biomed. Mater."},{"issue":"7","key":"10.1016\/j.jmbbm.2023.105974_b74","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1016\/S0883-5403(99)90035-9","article-title":"Cytokine response of human macrophage-like cells after contact with polyethylene and pure titanium particles","volume":"14","author":"Rader","year":"1999","journal-title":"J. Arthroplast."},{"issue":"4","key":"10.1016\/j.jmbbm.2023.105974_b75","doi-asserted-by":"crossref","first-page":"35","DOI":"10.3390\/dj5040035","article-title":"PEEK with reinforced materials and modifications for dental implant applications","volume":"5","author":"Rahmitasari","year":"2017","journal-title":"Dent. J."},{"key":"10.1016\/j.jmbbm.2023.105974_b76","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.polymdegradstab.2016.12.005","article-title":"Characterization of thermally annealed PEEK and CFR-PEEK composites: Structure-properties relationships","volume":"136","author":"Regis","year":"2017","journal-title":"Polym. Degrad. Stab."},{"key":"10.1016\/j.jmbbm.2023.105974_b77","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.wear.2018.05.005","article-title":"Wear behavior of medical grade PEEK and CFR PEEK under dry and bovine serum conditions","volume":"408\u2013409","author":"Regis","year":"2018","journal-title":"Wear"},{"key":"10.1016\/j.jmbbm.2023.105974_b78","series-title":"Morphology and Crystalline Architecture of Polyaryletherketones","first-page":"49","author":"Reitman","year":"2012"},{"issue":"4","key":"10.1016\/j.jmbbm.2023.105974_b79","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1002\/jbm.10159","article-title":"In vivo biocompatibility testing of peek polymer for a spinal implant system: a study in rabbits","volume":"62","author":"Rivard","year":"2002","journal-title":"J. Biomed. Mater. Res."},{"issue":"1","key":"10.1016\/j.jmbbm.2023.105974_b80","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s12306-015-0371-2","article-title":"Proximal humeral fracture fixation: multicenter study with carbon fiber peek plate","volume":"99","author":"Rotini","year":"2015","journal-title":"Musculoskelet. Surg."},{"issue":"8","key":"10.1016\/j.jmbbm.2023.105974_b81","doi-asserted-by":"crossref","first-page":"1282","DOI":"10.1016\/j.jse.2014.12.028","article-title":"Treatment of proximal humerus fractures with a CFR-PEEK plate: 2-year results of a prospective study and comparison to fixation with a conventional locking plate","volume":"24","author":"Schliemann","year":"2015","journal-title":"J. Shoulder Elb. Surg."},{"issue":"3","key":"10.1016\/j.jmbbm.2023.105974_b82","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1243\/09544119JEIM224","article-title":"The wear properties of CFR-PEEK-OPTIMA articulating against ceramic assessed on a multidirectional pin-on-plate machine","volume":"221","author":"Scholes","year":"2007","journal-title":"Proc. Inst. Mech. Eng. H"},{"issue":"1","key":"10.1016\/j.jmbbm.2023.105974_b83","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1007\/s10856-008-3558-3","article-title":"Wear studies on the likely performance of CFR-PEEK\/CoCrMo for use as artificial joint bearing materials","volume":"20","author":"Scholes","year":"2009","journal-title":"J. Mater. Sci., Mater. Med."},{"issue":"3","key":"10.1016\/j.jmbbm.2023.105974_b84","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1016\/j.wear.2009.08.023","article-title":"The wear performance of PEEK-OPTIMA based self-mating couples","volume":"268","author":"Scholes","year":"2010","journal-title":"Wear"},{"issue":"6","key":"10.1016\/j.jmbbm.2023.105974_b85","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1563\/AAID-JOI-D-11-00002","article-title":"PEEK dental implants: a review of the literature","volume":"39","author":"Schwitalla","year":"2013","journal-title":"J. Oral Implantol."},{"issue":"11","key":"10.1016\/j.jmbbm.2023.105974_b86","doi-asserted-by":"crossref","first-page":"1377","DOI":"10.1016\/j.dental.2015.08.151","article-title":"Flexural behavior of PEEK materials for dental application","volume":"31","author":"Schwitalla","year":"2015","journal-title":"Dent. Mater."},{"issue":"26","key":"10.1016\/j.jmbbm.2023.105974_b87","doi-asserted-by":"crossref","first-page":"4871","DOI":"10.1016\/S0142-9612(03)00403-4","article-title":"Use of a novel carbon fibre composite material for the femoral stem component of a THR system: in vitro biological assessment","volume":"24","author":"Scotchford","year":"2003","journal-title":"Biomaterials"},{"issue":"2","key":"10.1016\/j.jmbbm.2023.105974_b88","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1007\/BF00839070","article-title":"Methods for the evaluation of biocompatibility of soluble synthetic polymers which have potential for biomedical use: 1\u2014Use of the tetrazolium-based colorimetric assay (MTT) as a preliminary screen for evaluation of in vitro cytotoxicity","volume":"1","author":"Sgouras","year":"1990","journal-title":"J. Mater. Sci., Mater. Med."},{"issue":"1","key":"10.1016\/j.jmbbm.2023.105974_b89","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1002\/jbm.820280111","article-title":"Macrophage\/particle interactions: effect of size, composition and surface area","volume":"28","author":"Shanbhag","year":"1994","journal-title":"J. Biomed. Mater. Res."},{"issue":"5","key":"10.1016\/j.jmbbm.2023.105974_b90","doi-asserted-by":"crossref","first-page":"792","DOI":"10.1002\/jor.1100130520","article-title":"Human monocyte response to particulate biomaterials generated in vivo and in vitro","volume":"13","author":"Shanbhag","year":"1995","journal-title":"J. Orthop. Res."},{"key":"10.1016\/j.jmbbm.2023.105974_b91","series-title":"Sterilization Compatibility Overview \u2013 High-Performance Medical-Grade Plastics","author":"Solavy","year":"2017"},{"key":"10.1016\/j.jmbbm.2023.105974_b92","doi-asserted-by":"crossref","first-page":"2394","DOI":"10.1007\/s11999-016-4976-z","article-title":"The biologic response to polyetheretherketone (PEEK) wear particles in total joint replacement: a systematic review","volume":"474","author":"Stratton-Powell","year":"2016","journal-title":"Clin. Orthop. Relat. Res."},{"key":"10.1016\/j.jmbbm.2023.105974_b93","doi-asserted-by":"crossref","first-page":"646","DOI":"10.3109\/17453670903487008","article-title":"The association between metal allergy, total hip arthroplasty and revision","volume":"80","author":"Thyssen","year":"2009","journal-title":"Acta Orthop."},{"issue":"3","key":"10.1016\/j.jmbbm.2023.105974_b94","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1016\/j.biomaterials.2005.07.011","article-title":"Polyetheretherketone as a biomaterial for spinal applications","volume":"27","author":"Toth","year":"2006","journal-title":"Biomaterials"},{"issue":"11","key":"10.1016\/j.jmbbm.2023.105974_b95","doi-asserted-by":"crossref","first-page":"4296","DOI":"10.1016\/j.actbio.2010.06.002","article-title":"Inflammatory response against different carbon fiber-reinforced PEEK wear particles compared with UHMWPE in vivo","volume":"6","author":"Utzschneider","year":"2010","journal-title":"Acta Biomater."},{"key":"10.1016\/j.jmbbm.2023.105974_b96","doi-asserted-by":"crossref","DOI":"10.1016\/j.eurpolymj.2021.110295","article-title":"Developments of PEEK (polyetheretherketone) as a biomedical material: A focused review","author":"Verma","year":"2021","journal-title":"Eur. Polym. J."},{"issue":"2","key":"10.1016\/j.jmbbm.2023.105974_b97","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.orthres.2003.08.013","article-title":"The effectiveness of polyethylene versus titanium particles in inducing osteolysis in vivo","volume":"22","author":"von Knoch","year":"2004","journal-title":"J. Orthop. Res."},{"issue":"1\u20133","key":"10.1016\/j.jmbbm.2023.105974_b98","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/S0301-679X(98)00005-X","article-title":"Lubrication and wear of ultra-high molecular weight polyethylene in total joint replacements","volume":"31","author":"Wang","year":"1998","journal-title":"Tribol. Int."},{"key":"10.1016\/j.jmbbm.2023.105974_b99","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1016\/S0043-1648(99)00026-5","article-title":"Suitability and limitations of carbon fiber reinforced PEEK composites as bearing surfaces for total joint replacements","volume":"225\u2013229","author":"Wang","year":"1999","journal-title":"Wear"},{"issue":"2","key":"10.1016\/j.jmbbm.2023.105974_b100","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1520\/JTE11485J","article-title":"The significance of nonlinear motion in the wear screening of orthopaedic implant materials","volume":"25","author":"Wang","year":"1997","journal-title":"J. Test. Eval."},{"issue":"11","key":"10.1016\/j.jmbbm.2023.105974_b101","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1016\/S0301-679X(98)00088-7","article-title":"Carbon fiber reinforced polyether ether ketone composite as a bearing surface for total hip replacement","volume":"31","author":"Wang","year":"1998","journal-title":"Tribol. Int."},{"issue":"2","key":"10.1016\/j.jmbbm.2023.105974_b102","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1002\/jbm.820240207","article-title":"In vitro biocompatibility of polyetheretherketone and polysulfone composites","volume":"24","author":"Wenz","year":"1990","journal-title":"J. Biomed. Mater. Res."},{"issue":"2","key":"10.1016\/j.jmbbm.2023.105974_b103","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1007\/BF01728981","article-title":"Potential of polyetheretherketone (PEEK) and carbon-fibre-reinforced PEEK in medical applications","volume":"6","author":"Williams","year":"1987","journal-title":"J. Mater. Sci. Lett."},{"issue":"2","key":"10.1016\/j.jmbbm.2023.105974_b104","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1302\/0301-620X.93B2.25150","article-title":"Early metallosis-related failure after total knee replacement: a report of 15 cases","volume":"93","author":"Willis-Owen","year":"2011","journal-title":"J. Bone Joint Surg. [Br]"},{"key":"10.1016\/j.jmbbm.2023.105974_b105","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1097\/01.blo.0000150311.33227.b1","article-title":"Particles of all sizes provoke inflammatory responses in vivo.","volume":"433","author":"Zysk","year":"2005","journal-title":"Clin. Orthop. Relat. Res. (1976-2007)"}],"container-title":["Journal of the Mechanical Behavior of Biomedical Materials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1751616123003272?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1751616123003272?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,6,2]],"date-time":"2024-06-02T10:21:02Z","timestamp":1717323662000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1751616123003272"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9]]},"references-count":105,"alternative-id":["S1751616123003272"],"URL":"https:\/\/doi.org\/10.1016\/j.jmbbm.2023.105974","relation":{},"ISSN":["1751-6161"],"issn-type":[{"value":"1751-6161","type":"print"}],"subject":[],"published":{"date-parts":[[2023,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"An overview of the tribological and mechanical properties of PEEK and CFR-PEEK for use in total joint replacements","name":"articletitle","label":"Article Title"},{"value":"Journal of the Mechanical Behavior of Biomedical Materials","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jmbbm.2023.105974","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"105974"}}