{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T14:08:38Z","timestamp":1777644518139,"version":"3.51.4"},"reference-count":46,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["51901137"],"award-info":[{"award-number":["51901137"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["51735003"],"award-info":[{"award-number":["51735003"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the Mechanical Behavior of Biomedical Materials"],"published-print":{"date-parts":[[2025,1]]},"DOI":"10.1016\/j.jmbbm.2024.106790","type":"journal-article","created":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T05:00:19Z","timestamp":1730437219000},"page":"106790","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"special_numbering":"C","title":["Structural optimization and in vitro corrosion analysis of biodegradable Mg-Nd-Zn-Zr alloy clip"],"prefix":"10.1016","volume":"161","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-9730-1939","authenticated-orcid":false,"given":"Lin","family":"Mao","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-9376-4084","authenticated-orcid":false,"given":"Yujie","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-5480-6613","authenticated-orcid":false,"given":"Xin","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xue","family":"Cai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yilong","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wanwen","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jvxiao","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jian","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chengli","family":"Song","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jmbbm.2024.106790_bib1","doi-asserted-by":"crossref","DOI":"10.3389\/fsurg.2021.799442","article-title":"The development of laparoscopy\u2014a historical overview","volume":"8","author":"Alkatout","year":"2021","journal-title":"Front. Surg."},{"key":"10.1016\/j.jmbbm.2024.106790_bib2","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1308\/rcsann.2021.0264","article-title":"How should we secure the cystic duct during laparoscopic cholecystectomy? A UK-wide survey of clinical practice and systematic review of the literature with meta-analysis","volume":"104","author":"Arkle","year":"2022","journal-title":"annals"},{"key":"10.1016\/j.jmbbm.2024.106790_bib3","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1016\/j.jma.2020.08.002","article-title":"Review of Mg alloy corrosion rates","volume":"8","author":"Atrens","year":"2020","journal-title":"J. Magnesium Alloys"},{"key":"10.1016\/j.jmbbm.2024.106790_bib4","doi-asserted-by":"crossref","DOI":"10.1016\/j.corsci.2012.07.015","article-title":"Relationship between the corrosion behavior and the thermal characteristics and microstructure of Mg\u20130.5Ca\u2013xZn alloys","author":"Bakhsheshi-Rad","year":"2012","journal-title":"Corrosion Sci."},{"key":"10.1016\/j.jmbbm.2024.106790_bib5","doi-asserted-by":"crossref","DOI":"10.1016\/j.matdes.2013.06.055","article-title":"Mechanical and bio-corrosion properties of quaternary Mg\u2013Ca\u2013Mn\u2013Zn alloys compared with binary Mg\u2013Ca alloys","author":"Bakhsheshi-Rad","year":"2014","journal-title":"Mater. Des."},{"key":"10.1016\/j.jmbbm.2024.106790_bib6","doi-asserted-by":"crossref","DOI":"10.1016\/j.corsci.2022.110463","article-title":"A new look on the corrosion mechanism of magnesium: an EIS investigation at different pH","volume":"205","author":"Benbouzid","year":"2022","journal-title":"Corrosion Sci."},{"key":"10.1016\/j.jmbbm.2024.106790_bib7","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1016\/j.bbe.2020.02.003","article-title":"Biodegradable bone implants in orthopedic applications: a review","volume":"40","author":"Chandra","year":"2020","journal-title":"Biocybern. Biomed. Eng."},{"key":"10.1016\/j.jmbbm.2024.106790_bib8","doi-asserted-by":"crossref","unstructured":"Chen, X., Zhang, Jun, Chen, G., Xue, Y., Zhang, Jiajun, Liang, X., Lei, I.M., Lin, J., Xu, B.B., Liu, J., 2022. Hydrogel bioadhesives with extreme acid\u2010tolerance for gastric perforation repairing. Adv Funct Materials 32, 2202285. Cushing, H., n.d. Original Memoirs: The Control of Bleeding in Operations for Brain Tumors:.","DOI":"10.1002\/adfm.202270168"},{"key":"10.1016\/j.jmbbm.2024.106790_bib9","unstructured":"Delibegovi\u0107, S., Katica, M., Lati\u0107, F., Jaki\u0107-Razumovi\u0107, J., Koluh, A., Njoum, M.T., 2013, n.d. THE BIOCOMPATIBILITY OF TITANIUM CLIPS AFTER LAPAROSCOPIC APPENDECTOMY."},{"key":"10.1016\/j.jmbbm.2024.106790_bib10","first-page":"236","article-title":"In vitro and in vivo biocompatibility of Mg\u2013Zn\u2013Ca alloy operative clip","volume":"4","author":"Ding","year":"2019","journal-title":"Bioact. Mater."},{"key":"10.1016\/j.jmbbm.2024.106790_bib11","article-title":"Clarifying stress corrosion cracking behavior of biomedical Mg-Gd-Zn-Zr alloy","volume":"S2213956724002676","author":"Dong","year":"2024","journal-title":"J. Magnesium Alloys"},{"key":"10.1016\/j.jmbbm.2024.106790_bib12","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1016\/j.surg.2018.11.017","article-title":"Unfortunate adverse event resulting from clip migration after cholecystectomy","volume":"165","author":"Guilbaud","year":"2019","journal-title":"Surgery"},{"key":"10.1016\/j.jmbbm.2024.106790_bib13","doi-asserted-by":"crossref","DOI":"10.1016\/j.jmbbm.2021.104759","article-title":"The microstructure, mechanical properties, corrosion performance and biocompatibility of hydroxyapatite reinforced ZK61 magnesium-matrix biological composite","volume":"123","author":"Guo","year":"2021","journal-title":"J. Mech. Behav. Biomed. Mater."},{"key":"10.1016\/j.jmbbm.2024.106790_bib14","doi-asserted-by":"crossref","DOI":"10.1016\/j.jma.2018.04.003","article-title":"Fabrication of ultra-high strength magnesium alloys over 540 MPa with low alloying concentration by double continuously extrusion","author":"Huang","year":"2018","journal-title":"J. Magnesium Alloys"},{"key":"10.1016\/j.jmbbm.2024.106790_bib15","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1016\/j.actbio.2015.10.023","article-title":"Fabrication of a magnesium alloy with excellent ductility for biodegradable clips","volume":"29","author":"Ikeo","year":"2016","journal-title":"Acta Biomater."},{"key":"10.1016\/j.jmbbm.2024.106790_bib16","doi-asserted-by":"crossref","first-page":"1906","DOI":"10.1016\/j.jma.2023.05.011","article-title":"Stress corrosion cracking of magnesium alloys: a review","volume":"11","author":"Jiang","year":"2023","journal-title":"J. Magnesium Alloys"},{"key":"10.1016\/j.jmbbm.2024.106790_bib17","doi-asserted-by":"crossref","first-page":"1634","DOI":"10.1002\/jbm.a.36931","article-title":"Design of dental implants at materials level: an overview","volume":"108","author":"Jiang","year":"2020","journal-title":"J Biomedical Materials Res"},{"key":"10.1016\/j.jmbbm.2024.106790_bib18","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1016\/j.jmbbm.2017.09.032","article-title":"Bio-corrosion behavior and mechanical characteristics of magnesium-titania-hydroxyapatite nanocomposites coated by magnesium-oxide flakes and silicon for use as resorbable bone fixation material","volume":"77","author":"Khalajabadi","year":"2018","journal-title":"J. Mech. Behav. Biomed. Mater."},{"key":"10.1016\/j.jmbbm.2024.106790_bib19","doi-asserted-by":"crossref","first-page":"1574","DOI":"10.1016\/j.jbiomech.2004.07.022","article-title":"Cardiovascular stent design and vessel stresses: a finite element analysis","volume":"38","author":"Lally","year":"2005","journal-title":"J. Biomech."},{"key":"10.1016\/j.jmbbm.2024.106790_bib20","series-title":"Wounds: Biology and Management, Oxford Medical Publications","year":"1998"},{"key":"10.1016\/j.jmbbm.2024.106790_bib21","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1016\/j.actbio.2021.12.032","article-title":"In vitro and in vivo assessment of the effect of biodegradable magnesium alloys on osteogenesis","volume":"141","author":"Li","year":"2022","journal-title":"Acta Biomater."},{"key":"10.1016\/j.jmbbm.2024.106790_bib22","doi-asserted-by":"crossref","DOI":"10.1016\/j.pmatsci.2022.101011","article-title":"A review on the fatigue cracking of twin boundaries: crystallographic orientation and stacking fault energy","volume":"131","author":"Li","year":"2023","journal-title":"Prog. Mater. Sci."},{"key":"10.1016\/j.jmbbm.2024.106790_bib23","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1557\/mrs.2016.64","article-title":"Deformation twinning in hexagonal materials","volume":"41","author":"Liao","year":"2016","journal-title":"MRS Bull."},{"key":"10.1016\/j.jmbbm.2024.106790_bib24","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1080\/09506608.2022.2079367","article-title":"Biodegradable Mg-based alloys: biological implications and restorative opportunities","volume":"68","author":"Lin","year":"2023","journal-title":"Int. Mater. Rev."},{"key":"10.1016\/j.jmbbm.2024.106790_bib25","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.bioelechem.2019.05.001","article-title":"Fabrication of biodegradable HA\/Mg-Zn-Ca composites and the impact of heterogeneous microstructure on mechanical properties, in vitro degradation and cytocompatibility","volume":"129","author":"Liu","year":"2019","journal-title":"Bioelectrochemistry"},{"key":"10.1016\/j.jmbbm.2024.106790_bib26","doi-asserted-by":"crossref","first-page":"1","DOI":"10.4253\/wjge.v14.i1.1","article-title":"Safety considerations in laparoscopic surgery: a narrative review","volume":"14","author":"Madhok","year":"2022","journal-title":"WJGE"},{"key":"10.1016\/j.jmbbm.2024.106790_bib27","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1179\/imr.1993.38.3.138","article-title":"Corrosion of magnesium","volume":"38","author":"Makar","year":"1993","journal-title":"Int. Mater. Rev."},{"key":"10.1016\/j.jmbbm.2024.106790_bib28","doi-asserted-by":"crossref","first-page":"1979","DOI":"10.3390\/met12111979","article-title":"Structural optimization, fabrication, and corrosion behaviors of biodegradable Mg-Nd-Zn-Zr alloy hemostatic clip","volume":"12","author":"Mao","year":"2022","journal-title":"Metals"},{"key":"10.1016\/j.jmbbm.2024.106790_bib29","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.jallcom.2017.05.280","article-title":"Enhanced biocompatibility and long-term durability in vivo of Mg-Nd-Zn-Zr alloy for vascular stent application","volume":"720","author":"Mao","year":"2017","journal-title":"J. Alloys Compd."},{"key":"10.1016\/j.jmbbm.2024.106790_bib30","unstructured":"Nie, Y.-J., n.d. Effect of Ag Addition on Microstructure, Mechanical and Corrosion Properties of Mg\u2013Nd\u2013Zn\u2013Zr Alloy for Orthopedic Application."},{"key":"10.1016\/j.jmbbm.2024.106790_bib31","doi-asserted-by":"crossref","DOI":"10.18687\/LACCEI2022.1.1.792","article-title":"Developing trends in Mg alloys for biomedical implant applications","author":"Okafor","year":"2022"},{"key":"10.1016\/j.jmbbm.2024.106790_bib32","doi-asserted-by":"crossref","first-page":"3306","DOI":"10.1016\/j.jma.2022.10.025","article-title":"Corrosion in Mg-alloy biomedical implants- the strategies to reduce the impact of the corrosion inflammatory reaction and microbial activity","volume":"10","author":"Saha","year":"2022","journal-title":"J. Magnesium Alloys"},{"key":"10.1016\/j.jmbbm.2024.106790_bib33","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.actamat.2014.02.011","article-title":"Ductility improvement of Mg alloys by solid solution: ab initio modeling, synthesis and mechanical properties","volume":"70","author":"Sandl\u00f6bes","year":"2014","journal-title":"Acta Mater."},{"key":"10.1016\/j.jmbbm.2024.106790_bib34","doi-asserted-by":"crossref","first-page":"2498","DOI":"10.3390\/ma14102498","article-title":"Cardiovascular stents: a review of past, current, and emerging devices","volume":"14","author":"Scafa Udri\u0219te","year":"2021","journal-title":"Materials"},{"key":"10.1016\/j.jmbbm.2024.106790_bib35","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1016\/j.jma.2020.11.001","article-title":"Recent progress in in vivo studies and clinical applications of magnesium based biodegradable implants \u2013 a review","volume":"9","author":"Sekar","year":"2021","journal-title":"J. Magnesium Alloys"},{"key":"10.1016\/j.jmbbm.2024.106790_bib36","series-title":"The Use of Bipolar Cautery, Laparosonic Coagulating Shears, and Vascular Clips for Hemostasis of Small and Medium-Sized Vessels","author":"Spivak","year":"1998"},{"key":"10.1016\/j.jmbbm.2024.106790_bib37","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1016\/j.surfcoat.2013.10.051","article-title":"Electrochemical behavior of plasma electrolytic oxide coatings on rare earth element containing Mg alloys","volume":"236","author":"Tekin","year":"2013","journal-title":"Surf. Coating. Technol."},{"key":"10.1016\/j.jmbbm.2024.106790_bib38","doi-asserted-by":"crossref","first-page":"4653","DOI":"10.1007\/s00464-016-4778-0","article-title":"Vessel sealing comparison: old school is still hip","volume":"30","author":"Tharakan","year":"2016","journal-title":"Surg. Endosc."},{"key":"10.1016\/j.jmbbm.2024.106790_bib39","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.biomaterials.2018.07.018","article-title":"An innovative Mg\/Ti hybrid fixation system developed for fracture fixation and healing enhancement at load-bearing skeletal site","volume":"180","author":"Tian","year":"2018","journal-title":"Biomaterials"},{"key":"10.1016\/j.jmbbm.2024.106790_bib40","doi-asserted-by":"crossref","first-page":"1884","DOI":"10.1016\/j.jma.2021.06.024","article-title":"Biodegradable Mg alloys for orthopedic implants \u2013 a review","volume":"9","author":"Tsakiris","year":"2021","journal-title":"J. Magnesium Alloys"},{"key":"10.1016\/j.jmbbm.2024.106790_bib41","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ijfatigue.2015.11.010","article-title":"EBSD analysis of fatigue crack initiation behavior in coarse-grained AZ31 magnesium alloy","volume":"84","author":"Uematsu","year":"2016","journal-title":"Int. J. Fatig."},{"key":"10.1016\/j.jmbbm.2024.106790_bib42","doi-asserted-by":"crossref","first-page":"1553","DOI":"10.1016\/j.surg.2016.12.023","article-title":"Development of a new biodegradable operative clip made of a magnesium alloy: evaluation of its safety and tolerability for canine cholecystectomy","volume":"161","author":"Yoshida","year":"2017","journal-title":"Surgery"},{"key":"10.1016\/j.jmbbm.2024.106790_bib43","doi-asserted-by":"crossref","DOI":"10.1016\/j.msec.2020.111093","article-title":"In vitro and in vivo studies on the degradation and biosafety of Mg-Zn-Ca-Y alloy hemostatic clip with the carotid artery of SD rat model","volume":"115","author":"Yu","year":"2020","journal-title":"Mater. Sci. Eng. C"},{"key":"10.1016\/j.jmbbm.2024.106790_bib44","first-page":"385","article-title":"Controlled release of hydrogen by implantation of magnesium induces P53-mediated tumor cells apoptosis","volume":"9","author":"Zan","year":"2022","journal-title":"Bioact. Mater."},{"key":"10.1016\/j.jmbbm.2024.106790_bib45","first-page":"501","article-title":"Study on mechanical properties and degradation behavior of magnesium alloy vascular clip","volume":"14","author":"Zhang","year":"2023","journal-title":"J. Forensic Biomech."},{"key":"10.1016\/j.jmbbm.2024.106790_bib46","doi-asserted-by":"crossref","DOI":"10.1016\/j.msec.2020.110779","article-title":"Simultaneous enhancement of anti-corrosion, biocompatibility, and antimicrobial activities by hierarchically-structured brushite\/Ag3PO4-coated Mg-based scaffolds","volume":"111","author":"Zhang","year":"2020","journal-title":"Mater. Sci. Eng. C"}],"container-title":["Journal of the Mechanical Behavior of Biomedical Materials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1751616124004223?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1751616124004223?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T13:53:29Z","timestamp":1746107609000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1751616124004223"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":46,"alternative-id":["S1751616124004223"],"URL":"https:\/\/doi.org\/10.1016\/j.jmbbm.2024.106790","relation":{},"ISSN":["1751-6161"],"issn-type":[{"value":"1751-6161","type":"print"}],"subject":[],"published":{"date-parts":[[2025,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Structural optimization and in vitro corrosion analysis of biodegradable Mg-Nd-Zn-Zr alloy clip","name":"articletitle","label":"Article Title"},{"value":"Journal of the Mechanical Behavior of Biomedical Materials","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jmbbm.2024.106790","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"106790"}}