{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T20:53:13Z","timestamp":1761166393321,"version":"build-2065373602"},"reference-count":27,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["16K11525"],"award-info":[{"award-number":["16K11525"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Molecular Graphics and Modelling"],"published-print":{"date-parts":[[2018,1]]},"DOI":"10.1016\/j.jmgm.2017.11.013","type":"journal-article","created":{"date-parts":[[2017,11,28]],"date-time":"2017-11-28T22:30:22Z","timestamp":1511908222000},"page":"185-191","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Structural comparison among the 2013\u20132017 avian influenza A H5N6 hemagglutinin proteins: A computational study with epidemiological implications"],"prefix":"10.1016","volume":"79","author":[{"given":"Marni E.","family":"Cueno","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Izuho","family":"Suzuki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shiori","family":"Shimotomai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takuma","family":"Yokoyama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kai","family":"Nagahisa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenichi","family":"Imai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jmgm.2017.11.013_bib0005","doi-asserted-by":"crossref","first-page":"1805","DOI":"10.1099\/vir.0.2008\/002469-0","article-title":"Positive selection at the receptor-binding site of haemagglutinin H5 in viral sequences derived from human tissues","volume":"89","author":"Kongchanagul","year":"2008","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.jmgm.2017.11.013_bib0010","first-page":"1","article-title":"Evolutionary dynamics of N-glycosylation sites of influenza virus hemagglutinin","author":"Cherry","year":"2009","journal-title":"PLoS Curr."},{"key":"10.1016\/j.jmgm.2017.11.013_bib0015","doi-asserted-by":"crossref","first-page":"e1001211","DOI":"10.1371\/journal.ppat.1001211","article-title":"Glycosylation focuses sequence variation in the influenza A virus H1 hemagglutinin globular domain","volume":"6","author":"Das","year":"2010","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.jmgm.2017.11.013_bib0020","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1038\/23974","article-title":"Structure of the haemagglutinin-esterase-fusion glycoprotein of influenza C virus","volume":"396","author":"Rosenthal","year":"1998","journal-title":"Nature"},{"key":"10.1016\/j.jmgm.2017.11.013_bib0025","doi-asserted-by":"crossref","first-page":"e18664","DOI":"10.1371\/journal.pone.0018664","article-title":"Rapid estimation of binding activity of influenza virus hemagglutinin to human and avian receptors","volume":"6","author":"Cao","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.jmgm.2017.11.013_bib0030","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1126\/science.1178258","article-title":"Hemagglutinin receptor binding avidity drives influenza A virus antigenic drift","volume":"326","author":"Hensley","year":"2009","journal-title":"Science"},{"key":"10.1016\/j.jmgm.2017.11.013_bib0035","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1038\/srep00200","article-title":"Networks link antigenic and receptor-binding sites of influenza hemagglutinin: mechanistic insight into fitter strain propagation","volume":"1","author":"Soundararajan","year":"2011","journal-title":"Sci. Rep."},{"issue":"6","key":"10.1016\/j.jmgm.2017.11.013_bib0040","first-page":"29888","article-title":"Novel avian influenza A (H5N6) viruses isolated in migratory waterfowl before the first human case reported in China","volume":"2016","author":"Bi","year":"2014","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jmgm.2017.11.013_bib0045","doi-asserted-by":"crossref","first-page":"44410","DOI":"10.1038\/srep44410","article-title":"Highly pathogenic H5N6 influenza A viruses recovered from wild birds in Guangdong, southern China, 2014\u20132015","volume":"7","author":"Kang","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jmgm.2017.11.013_bib0050","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1007\/s12288-015-0550-1","article-title":"Anemia and thrombocytopenia in new H5N6 influenza: existed or not?","volume":"32","author":"Joob","year":"2015","journal-title":"Indian J. Hematol. Blood Transfus."},{"key":"10.1016\/j.jmgm.2017.11.013_bib0055","doi-asserted-by":"crossref","first-page":"e50","DOI":"10.1038\/emi.2017.38","article-title":"Human infections with novel reassortant H5N6 avian influenza viruses in China","volume":"6","author":"Zhang","year":"2017","journal-title":"Emerg. Microbes Infect."},{"key":"10.1016\/j.jmgm.2017.11.013_bib0060","first-page":"260","article-title":"Genetic characterization of continually evolving highly pathogenic H5N6 influenza viruses in China, 2012\u20132016","volume":"8","author":"Li","year":"2017","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.jmgm.2017.11.013_bib0065","doi-asserted-by":"crossref","first-page":"W590","DOI":"10.1093\/nar\/gkh477","article-title":"SuperPose: a simple server for sophisticated structural superposition","volume":"32","author":"Maiti","year":"2004","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.jmgm.2017.11.013_bib0070","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1038\/289366a0","article-title":"Structure of the haemagglutinin membrane glycoprotein of influenza virus at 3A resolution","volume":"289","author":"Wilson","year":"1981","journal-title":"Nature"},{"key":"10.1016\/j.jmgm.2017.11.013_bib0075","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1038\/nprot.2009.2","article-title":"Protein structure prediction on the Web: a case study using the Phyre server","volume":"4","author":"Kelley","year":"2009","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.jmgm.2017.11.013_bib0080","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1093\/bioinformatics\/16.4.404","article-title":"The PSIPRED protein structure prediction server","volume":"16","author":"McGuffin","year":"2000","journal-title":"Bioinformatics"},{"key":"10.1016\/j.jmgm.2017.11.013_bib0085","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1002\/prot.10082","article-title":"Improving the prediction of protein secondary structure in three and eight classes using recurrent neural networks and profiles","volume":"47","author":"Pollastri","year":"2002","journal-title":"Proteins"},{"key":"10.1016\/j.jmgm.2017.11.013_bib0090","doi-asserted-by":"crossref","first-page":"W197","DOI":"10.1093\/nar\/gkn238","article-title":"The Jpred 3 secondary structure prediction server","volume":"36","author":"Cole","year":"2008","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.jmgm.2017.11.013_bib0095","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1002\/prot.21688","article-title":"Exploring the extremes of sequence\/structure space with ensemble fold recognition in the program Phyre","volume":"70","author":"Bennett-Lovsey","year":"2008","journal-title":"Proteins"},{"key":"10.1016\/j.jmgm.2017.11.013_bib0100","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1002\/bmb.2006.494034042644","article-title":"Biomolecules in the computer: jmol to the rescue","volume":"34","author":"Herraez","year":"2006","journal-title":"Biochem. Mol. Biol. Educ."},{"key":"10.1016\/j.jmgm.2017.11.013_bib0105","doi-asserted-by":"crossref","first-page":"1278","DOI":"10.1093\/bioinformatics\/bts139","article-title":"MDWeb and MDMoby: an integrated web-based platform for molecular dynamics simulations","volume":"28","author":"Hospital","year":"2012","journal-title":"Bioinformatics"},{"key":"10.1016\/j.jmgm.2017.11.013_bib0110","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1002\/prot.21715","article-title":"QMEAN: a comprehensive scoring function for model quality assessment","volume":"71","author":"Benkert","year":"2008","journal-title":"Proteins"},{"key":"10.1016\/j.jmgm.2017.11.013_bib0115","doi-asserted-by":"crossref","first-page":"W510","DOI":"10.1093\/nar\/gkp322","article-title":"QMEAN server for protein model quality estimation","volume":"37","author":"Benkert","year":"2009","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.jmgm.2017.11.013_bib0120","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1016\/j.str.2006.06.005","article-title":"Outcome of a workshop on archiving structural models of biological macromolecules","volume":"14","author":"Berman","year":"2006","journal-title":"Structure"},{"key":"10.1016\/j.jmgm.2017.11.013_bib0125","doi-asserted-by":"crossref","first-page":"8590","DOI":"10.1021\/acs.jpcb.6b02655","article-title":"Microsecond molecular dynamics simulations of influenza neuraminidase suggest a mechanism for the increased virulence of stalk-Deletion mutants","volume":"120","author":"Durrant","year":"2016","journal-title":"J. Phys. Chem. B"},{"key":"10.1016\/j.jmgm.2017.11.013_bib0130","doi-asserted-by":"crossref","first-page":"1239","DOI":"10.1016\/S0022-2836(03)00021-4","article-title":"An orientation-dependent hydrogen bonding potential improves prediction of specificity and structure for proteins and protein\u2013protein complexes","volume":"326","author":"Kortemme","year":"2003","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.jmgm.2017.11.013_bib0135","doi-asserted-by":"crossref","first-page":"1415","DOI":"10.1110\/ps.4890102","article-title":"An improved hydrogen bond potential: impact on medium resolution protein structures","volume":"11","author":"Fabiola","year":"2002","journal-title":"Protein Sci."}],"container-title":["Journal of Molecular Graphics and Modelling"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1093326317305843?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1093326317305843?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T20:57:27Z","timestamp":1761080247000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1093326317305843"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,1]]},"references-count":27,"alternative-id":["S1093326317305843"],"URL":"https:\/\/doi.org\/10.1016\/j.jmgm.2017.11.013","relation":{},"ISSN":["1093-3263"],"issn-type":[{"type":"print","value":"1093-3263"}],"subject":[],"published":{"date-parts":[[2018,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Structural comparison among the 2013\u20132017 avian influenza A H5N6 hemagglutinin proteins: A computational study with epidemiological implications","name":"articletitle","label":"Article Title"},{"value":"Journal of Molecular Graphics and Modelling","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jmgm.2017.11.013","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}