{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T11:21:41Z","timestamp":1773660101214,"version":"3.50.1"},"reference-count":21,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Molecular Graphics and Modelling"],"published-print":{"date-parts":[[2023,11]]},"DOI":"10.1016\/j.jmgm.2023.108572","type":"journal-article","created":{"date-parts":[[2023,7,21]],"date-time":"2023-07-21T03:04:42Z","timestamp":1689908682000},"page":"108572","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Structural dynamics of moonlighting intrinsically disordered proteins - A black box in multiple sclerosis"],"prefix":"10.1016","volume":"124","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8264-9476","authenticated-orcid":false,"given":"L.","family":"Ramya","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Helina Hilda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jmgm.2023.108572_bib1","series-title":"Basic Neurochemistry: Molecular, Cellular and Medical Aspects","article-title":"Characteristic composition of myelin","author":"Morell","year":"1999"},{"issue":"4","key":"10.1016\/j.jmgm.2023.108572_bib2","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/j.autrev.2009.08.002","article-title":"The myelin-associated oligodendrocytic basic protein (MOBP) as a relevant primary target autoantigen in multiple sclerosis","volume":"9","author":"Kaushansky","year":"2010","journal-title":"Autoimmun. Rev."},{"issue":"8","key":"10.1016\/j.jmgm.2023.108572_bib3","doi-asserted-by":"crossref","first-page":"1845","DOI":"10.1007\/s11064-016-1920-2","article-title":"Myelin basic protein citrullination in multiple sclerosis: a potential therapeutic target for pathology","volume":"41","author":"Yang","year":"2016","journal-title":"Neurochem. Res."},{"key":"10.1016\/j.jmgm.2023.108572_bib4","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1007\/s00726-021-03111-7","article-title":"Multiple sclerosis and myelin basic protein: insights into protein disorder and disease","volume":"54","author":"Martinsen","year":"2022","journal-title":"Amino Acids"},{"key":"10.1016\/j.jmgm.2023.108572_bib5","doi-asserted-by":"crossref","first-page":"1426","DOI":"10.4049\/jimmunol.173.2.1426","article-title":"The myelin-associated oligodendrocytic basic protein region MOBP15-36 encompasses the immunodominant major encephalitogenic epitope(s) for SJL\/J mice and predicted epitope(s) for multiple sclerosis-associated HLA-DRB1\u204e1501","volume":"173","author":"de Rosbo","year":"2004","journal-title":"J. Immunol."},{"key":"10.1016\/j.jmgm.2023.108572_bib6","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1039\/b900658n","article-title":"Moonlighting proteins--an update","volume":"5","author":"Jeffery","year":"2009","journal-title":"Mol. Biosyst."},{"key":"10.1016\/j.jmgm.2023.108572_bib7","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1002\/bies.201100191","article-title":"Moonlighting is mainstream: paradigm adjustment required","volume":"34","author":"Copley","year":"2012","journal-title":"Bioessays"},{"key":"10.1016\/j.jmgm.2023.108572_bib8","doi-asserted-by":"crossref","first-page":"D640","DOI":"10.1093\/nar\/gkx1043","article-title":"MoonProt 2.0: an expansion and update of the moonlighting proteins database","volume":"46","author":"Chen","year":"2018","journal-title":"Nucleic Acids Res."},{"issue":"1\u201318","key":"10.1016\/j.jmgm.2023.108572_bib9","doi-asserted-by":"crossref","first-page":"3440","DOI":"10.3390\/molecules25153440","article-title":"Moonlighting proteins in the fuzzy logic of cellular metabolism","volume":"25","author":"Liu","year":"2020","journal-title":"Molecules"},{"key":"10.1016\/j.jmgm.2023.108572_bib10","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1002\/prot.25590","article-title":"High-throughput prediction of disordered moonlighting regions in protein sequences","volume":"86","author":"Meng","year":"2018","journal-title":"Proteins"},{"issue":"34","key":"10.1016\/j.jmgm.2023.108572_bib11","doi-asserted-by":"crossref","first-page":"16856","DOI":"10.1073\/pnas.1821309116","article-title":"Distance-based protein folding powered by deep learning","volume":"116","author":"Xu","year":"2019","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.jmgm.2023.108572_bib12","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1107\/S0021889892009944","article-title":"Procheck - a program to check the stereochemical quality of protein structures","volume":"26","author":"Laskowski","year":"1993","journal-title":"J. Appl. Crystallogr."},{"key":"10.1016\/j.jmgm.2023.108572_bib13","series-title":"AMBER 2018","author":"Case","year":"2018"},{"key":"10.1016\/j.jmgm.2023.108572_bib14","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1063\/1.445869","article-title":"Comparison of simple potential functions for simulating liquid water","volume":"79","author":"Jorgensen","year":"1983","journal-title":"J. Chem. Phys."},{"issue":"8","key":"10.1016\/j.jmgm.2023.108572_bib15","doi-asserted-by":"crossref","first-page":"3696","DOI":"10.1021\/acs.jctc.5b00255","article-title":"ff14SB: Improving the accuracy of protein side chain and backbone parameters from ff99SB","volume":"11","author":"Maier","year":"2015","journal-title":"J Chem Theory Comput"},{"issue":"7","key":"10.1016\/j.jmgm.2023.108572_bib16","doi-asserted-by":"crossref","first-page":"3084","DOI":"10.1021\/ct400341p","article-title":"PTRAJ and CPPTRAJ: software for processing and analysis of molecular dynamics trajectory data","volume":"9","author":"Roe","year":"2013","journal-title":"J Chem Theory Comput"},{"issue":"40","key":"10.1016\/j.jmgm.2023.108572_bib17","doi-asserted-by":"crossref","first-page":"D370","DOI":"10.1093\/nar\/gkr703","article-title":"OPM database and PPM web server: resources for positioning of proteins in membranes","volume":"2","author":"Lomize","year":"2012","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.jmgm.2023.108572_bib18","doi-asserted-by":"crossref","first-page":"1997","DOI":"10.1002\/jcc.23702","article-title":"CHARMM-GUI membrane builder toward realistic biological membrane simulations","volume":"35","author":"Wu","year":"2014","journal-title":"J. Comput. Chem."},{"key":"10.1016\/j.jmgm.2023.108572_bib19","doi-asserted-by":"crossref","first-page":"8000","DOI":"10.1038\/s41598-019-44318-9","article-title":"Role of lipid composition on the structural and mechanical features of axonal membranes: a molecular simulation study","volume":"9","author":"Saeedimasine","year":"2019","journal-title":"Sci. Rep."},{"issue":"1","key":"10.1016\/j.jmgm.2023.108572_bib20","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1038\/nmeth.4067","article-title":"CHARMM36m: an improved force field for folded and intrinsically disordered proteins","volume":"14","author":"Huang","year":"2017","journal-title":"Nat. Methods"},{"key":"10.1016\/j.jmgm.2023.108572_bib21","doi-asserted-by":"crossref","first-page":"1781","DOI":"10.1002\/jcc.20289","article-title":"Scalable molecular dynamics with NAMD","volume":"26","author":"Phillips","year":"2005","journal-title":"J. Comput. Chem."}],"container-title":["Journal of Molecular Graphics and Modelling"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1093326323001705?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1093326323001705?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T21:16:12Z","timestamp":1761081372000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1093326323001705"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11]]},"references-count":21,"alternative-id":["S1093326323001705"],"URL":"https:\/\/doi.org\/10.1016\/j.jmgm.2023.108572","relation":{},"ISSN":["1093-3263"],"issn-type":[{"value":"1093-3263","type":"print"}],"subject":[],"published":{"date-parts":[[2023,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Structural dynamics of moonlighting intrinsically disordered proteins - A black box in multiple sclerosis","name":"articletitle","label":"Article Title"},{"value":"Journal of Molecular Graphics and Modelling","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jmgm.2023.108572","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"108572"}}