{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T02:23:49Z","timestamp":1787279029932,"version":"build-2736575974"},"reference-count":55,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jmig.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Minimally Invasive Gynecology"],"published-print":{"date-parts":[[2026,8]]},"DOI":"10.1016\/j.jmig.2026.03.028","type":"journal-article","created":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T19:00:47Z","timestamp":1774465247000},"page":"1086-1099","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Total Versus Sub-Total Hysterectomy: A Meta-Analysis of Randomized Controlled Trials"],"prefix":"10.1016","volume":"33","author":[{"given":"Giulia","family":"Bonavina","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gianluca","family":"Bonitta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-1382-1727","authenticated-orcid":false,"given":"Elena","family":"Puzzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Busnelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto","family":"Aiolfi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liliana","family":"Mereu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Massimo","family":"Candiani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"Bulfoni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jmig.2026.03.028_bib0001","article-title":"\u00dcber die Exstirpation des Uterus durch die Scheide","author":"Langenbeck","year":"1813","journal-title":"G\u00f6ttingen: Medizinisch-chirurgische Akademie"},{"key":"10.1016\/j.jmig.2026.03.028_bib0002","first-page":"248","article-title":"A simplified technique for abdominal panhysterectomy","volume":"48","author":"Richardson","year":"1929","journal-title":"Surg Gynecol Obstet"},{"key":"10.1016\/j.jmig.2026.03.028_bib0003","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.jmig.2013.08.001","article-title":"AAGL practice report: practice guidelines for laparoscopic subtotal\/supracervical hysterectomy (LSH)","volume":"21","year":"2014","journal-title":"J Minim Invasive Gynecol"},{"key":"10.1016\/j.jmig.2026.03.028_bib0004","series-title":"Laparoscopic uterine power morcellation in hysterectomy and myomectomy: FDA safety communication","year":"2014"},{"issue":"2","key":"10.1016\/j.jmig.2026.03.028_bib0005","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/j.ajog.2025.09.033","article-title":"Outcome of supracervical compared to total hysterectomy for emergency peripartum hemorrhage: a systematic review and meta-analysis","volume":"234","author":"Lucidi","year":"2026","journal-title":"Am J Obstet Gynecol"},{"issue":"4","key":"10.1016\/j.jmig.2026.03.028_bib0006","article-title":"Total versus subtotal hysterectomy for benign gynaecological conditions","author":"Lethaby","year":"2012","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.jmig.2026.03.028_bib0007","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1080\/00016340601024716","article-title":"Total or subtotal hysterectomy for benign uterine diseases? A meta-analysis","volume":"86","author":"Gimbel","year":"2007","journal-title":"Acta Obstet Gynecol Scand"},{"key":"10.1016\/j.jmig.2026.03.028_bib0008","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1016\/j.ajog.2007.09.033","article-title":"Postoperative urinary incontinence after total abdominal hysterectomy or supracervical hysterectomy: a metaanalysis","volume":"198","author":"Robert","year":"2008","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.jmig.2026.03.028_bib0009","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1007\/s00192-018-3811-3","article-title":"Pelvic floor symptoms 5 to 14 years after total versus subtotal hysterectomy for benign conditions: a systematic review and meta-analysis","volume":"30","author":"Aleixo","year":"2019","journal-title":"Int Urogynecol J"},{"key":"10.1016\/j.jmig.2026.03.028_bib0010","doi-asserted-by":"crossref","first-page":"n71","DOI":"10.1136\/bmj.n71","article-title":"The PRISMA 2020 statement: an updated guideline for reporting systematic reviews","volume":"372","author":"Page","year":"2021","journal-title":"BMJ"},{"key":"10.1016\/j.jmig.2026.03.028_bib0011","unstructured":"National Cancer Institute. NCI Dictionary of Cancer Terms. Bethesda (MD): National Cancer Institute; [cited 2025, Oct 13]. Available from: https:\/\/www.cancer.gov\/publications\/dictionaries\/cancer-terms"},{"key":"10.1016\/j.jmig.2026.03.028_bib0012","doi-asserted-by":"crossref","first-page":"1102","DOI":"10.1111\/1471-0528.13362","article-title":"Pain reduction after total laparoscopic hysterectomy and laparoscopic supracervical hysterectomy among women with dysmenorrhoea: a randomised controlled trial","volume":"122","author":"Berner","year":"2015","journal-title":"BJOG"},{"key":"10.1016\/j.jmig.2026.03.028_bib0013","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.ejogrb.2015.06.033","article-title":"Objective comparison of subtotal vs. total abdominal hysterectomy regarding pelvic organ prolapse and urinary incontinence: a randomized controlled trial with 14-year follow-up","volume":"193","author":"Andersen","year":"2015","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"issue":"12","key":"10.1016\/j.jmig.2026.03.028_bib0014","doi-asserted-by":"crossref","first-page":"1767","DOI":"10.1007\/s00192-015-2778-6","article-title":"Lower urinary tract symptoms after subtotal versus total abdominal hysterectomy: exploratory analyses from a randomized clinical trial with a 14-year follow-up","volume":"26","author":"Andersen","year":"2015","journal-title":"Int Urogynecol J"},{"issue":"6","key":"10.1016\/j.jmig.2026.03.028_bib0015","doi-asserted-by":"crossref","DOI":"10.1016\/j.ajog.2014.12.039","article-title":"Danish Hysterectomy Trial Group. Subtotal versus total abdominal hysterectomy: randomized clinical trial with 14-year questionnaire follow-up","volume":"212","author":"Andersen","year":"2015","journal-title":"Am J Obstet Gynecol"},{"issue":"6","key":"10.1016\/j.jmig.2026.03.028_bib0016","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1111\/1471-0528.12914","article-title":"Five-year follow up of a randomised controlled trial comparing subtotal with total abdominal hysterectomy","volume":"122","author":"Andersen","year":"2015","journal-title":"BJOG"},{"issue":"3","key":"10.1016\/j.jmig.2026.03.028_bib0017","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1016\/j.jmig.2013.01.003","article-title":"Laparoscopic supracervical hysterectomy performed with and without excision of the endocervix: a randomized controlled trial","volume":"20","author":"Berner","year":"2013","journal-title":"J Minim Invasive Gynecol"},{"issue":"12","key":"10.1016\/j.jmig.2026.03.028_bib0018","doi-asserted-by":"crossref","first-page":"1556","DOI":"10.1111\/1471-0528.12399","article-title":"Pelvic organ prolapse after subtotal and total hysterectomy: a long-term follow-up of an open randomised controlled multicentre study","volume":"120","author":"Persson","year":"2013","journal-title":"BJOG"},{"issue":"1","key":"10.1016\/j.jmig.2026.03.028_bib0019","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1097\/SPV.0b013e3181cec343","article-title":"Long-term outcomes of the total or supracervical hysterectomy (TOSH) trial","volume":"16","author":"Greer","year":"2010","journal-title":"Female Pelvic Med Reconstr Surg"},{"issue":"1","key":"10.1016\/j.jmig.2026.03.028_bib0020","doi-asserted-by":"crossref","first-page":"65","DOI":"10.3109\/00016340903353276","article-title":"A randomized trial comparing changes in sexual health and psychological well-being after subtotal and total hysterectomies","volume":"89","author":"Ellstr\u00f6m Engh","year":"2010","journal-title":"Acta Obstet Gynecol Scand"},{"issue":"2","key":"10.1016\/j.jmig.2026.03.028_bib0021","doi-asserted-by":"crossref","first-page":"176","DOI":"10.26719\/2010.16.2.176","article-title":"Outcomes of total versus subtotal abdominal hysterectomy","volume":"16","author":"Asnafi","year":"2010","journal-title":"East Mediterr Health J"},{"issue":"4","key":"10.1016\/j.jmig.2026.03.028_bib0022","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1111\/j.1471-0528.2009.02467.x","article-title":"A 1-year follow up of psychological wellbeing after subtotal and total hysterectomy\u2013a randomised study","volume":"117","author":"Persson","year":"2010","journal-title":"BJOG"},{"key":"10.1016\/j.jmig.2026.03.028_bib0023","first-page":"393","article-title":"Total versus subtotal laparoscopic hysterectomy: a comparative study in Arash Hospital","volume":"69","author":"Asgari","year":"2009","journal-title":"Tehran University Medical Journal"},{"issue":"5","key":"10.1016\/j.jmig.2026.03.028_bib0024","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1007\/s00404-008-0615-6","article-title":"Hysterectomy and women satisfaction: total versus subtotal technique","volume":"278","author":"Gorlero","year":"2008","journal-title":"Arch Gynecol Obstet"},{"issue":"6","key":"10.1016\/j.jmig.2026.03.028_bib0025","doi-asserted-by":"crossref","first-page":"1262","DOI":"10.1097\/AOG.0b013e31818f3bf5","article-title":"Removing the cervix at hysterectomy: an unnecessary intervention?","volume":"112","author":"Thakar","year":"2008","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.jmig.2026.03.028_bib0026","first-page":"1","article-title":"Laparascopic supracervical hysterectomy versus laparoscopic total hysterectomy: a prospective randomized study [Isterectomia sopracervicale laparoscopica versus isterectomia totale laparoscopica]","volume":"59","author":"Morelli","year":"2007","journal-title":"Minerva Ginecologica"},{"key":"10.1016\/j.jmig.2026.03.028_bib0027","first-page":"31","article-title":"Sexual satisfaction in total and subtotal abdominal hysterectomy: a randomized clinical trial","volume":"65","author":"Ghanbari","year":"2007","journal-title":"Tehran Univ Med J"},{"issue":"3","key":"10.1016\/j.jmig.2026.03.028_bib0028","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1111\/j.1743-6109.2006.00229.x","article-title":"The psychosocial outcomes of total and subtotal hysterectomy: a randomized controlled trial","volume":"3","author":"Flory","year":"2006","journal-title":"J Sex Med"},{"issue":"4","key":"10.1016\/j.jmig.2026.03.028_bib0029","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1007\/s00192-005-1291-8","article-title":"Lower urinary tract symptoms after total and subtotal hysterectomy: results of a randomized controlled trial","volume":"16","author":"Gimbel","year":"2005","journal-title":"Int Urogynecol J Pelvic Floor Dysfunct"},{"issue":"6","key":"10.1016\/j.jmig.2026.03.028_bib0030","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1097\/01.AOG.0000160428.81371.be","article-title":"Total or Supracervical Hysterectomy Research Group. Sexual functioning after total compared with supracervical hysterectomy: a randomized trial","volume":"105","author":"Kuppermann","year":"2005","journal-title":"Obstet Gynecol"},{"issue":"2","key":"10.1016\/j.jmig.2026.03.028_bib0031","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1111\/j.0001-6349.2004.00311.x","article-title":"Sexuality after total vs. subtotal hysterectomy","volume":"83","author":"Zobbe","year":"2004","journal-title":"Acta Obstet Gynecol Scand"},{"issue":"10","key":"10.1016\/j.jmig.2026.03.028_bib0032","doi-asserted-by":"crossref","first-page":"1115","DOI":"10.1111\/j.1471-0528.2004.00242.x","article-title":"Hysterectomy improves quality of life and decreases psychiatric symptoms: a prospective and randomised comparison of total versus subtotal hysterectomy","volume":"111","author":"Thakar","year":"2004","journal-title":"BJOG"},{"issue":"12","key":"10.1016\/j.jmig.2026.03.028_bib0033","first-page":"1088","article-title":"Randomised controlled trial of total compared with subtotal hysterectomy with one-year follow up results","volume":"110","author":"Gimbel","year":"2003","journal-title":"BJOG"},{"issue":"3","key":"10.1016\/j.jmig.2026.03.028_bib0034","first-page":"453","article-title":"A randomized comparison of total or supracervical hysterectomy: surgical complications and clinical outcomes","volume":"102","author":"Learman","year":"2003","journal-title":"Obstet Gynecol"},{"issue":"17","key":"10.1016\/j.jmig.2026.03.028_bib0035","doi-asserted-by":"crossref","first-page":"1318","DOI":"10.1056\/NEJMoa013336","article-title":"Outcomes after total versus subtotal abdominal hysterectomy","volume":"347","author":"Thakar","year":"2002","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jmig.2026.03.028_bib0036","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/S0002-9378(96)70243-0","article-title":"The standardization of terminology of female pelvic organ prolapse and pelvic floor dysfunction","volume":"175","author":"Bump","year":"1996","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.jmig.2026.03.028_bib0037","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1002\/nau.1930140206","article-title":"Short forms to assess life quality and symptom distress for urinary incontinence in women: the Incontinence Impact Questionnaire and the Urogenital Distress Inventory. Continence Program for Women Research Group","volume":"14","author":"Uebersax","year":"1995","journal-title":"Neurourol Urodyn"},{"key":"10.1016\/j.jmig.2026.03.028_bib0038","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1002\/nau.10052","article-title":"The standardisation of terminology of lower urinary tract function: report from the standardisation sub-committee of the International Continence Society","volume":"21","author":"Abrams","year":"2002","journal-title":"Neurourol Urodyn"},{"issue":"1","key":"10.1016\/j.jmig.2026.03.028_bib0039","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.ajog.2004.12.025","article-title":"Short forms of two condition-specific quality-of-life questionnaires for women with pelvic floor disorders (PFDI-20 and PFIQ-7)","volume":"193","author":"Barber","year":"2005","journal-title":"Am J Obstet Gynecol"},{"issue":"5","key":"10.1016\/j.jmig.2026.03.028_bib0040","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1007\/s11934-019-0888-2","article-title":"Patient-reported outcome measures (PROMs) in pelvic floor disorders","volume":"20","author":"Habashy","year":"2019","journal-title":"Curr Urol Rep"},{"key":"10.1016\/j.jmig.2026.03.028_bib0041","series-title":"Assessment of Quality of Life in Clinical Trials of Cardiovascular Therapies","first-page":"170","article-title":"The psychological general well-being (PGWB) index","author":"Dupuy","year":"1984"},{"issue":"6","key":"10.1016\/j.jmig.2026.03.028_bib0042","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1097\/00005650-199206000-00002","article-title":"The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection","volume":"30","author":"Ware","year":"1992","journal-title":"Med Care"},{"key":"10.1016\/j.jmig.2026.03.028_bib0043","doi-asserted-by":"crossref","first-page":"l4898","DOI":"10.1136\/bmj.l4898","article-title":"RoB 2: a revised tool for assessing risk of bias in randomised trials","volume":"366","author":"Sterne","year":"2019","journal-title":"BMJ"},{"issue":"7650","key":"10.1016\/j.jmig.2026.03.028_bib0044","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1136\/bmj.39489.470347.AD","article-title":"GRADE: an emerging consensus on rating quality of evidence and strength of recommendations","volume":"336","author":"Guyatt","year":"2008","journal-title":"BMJ"},{"issue":"6","key":"10.1016\/j.jmig.2026.03.028_bib0045","doi-asserted-by":"crossref","first-page":"1785","DOI":"10.1177\/0962280216669183","article-title":"Optimally estimating the sample mean from the sample size, median, mid-range, and\/or mid-quartile range","volume":"27","author":"Luo","year":"2018","journal-title":"Stat Methods Med Res"},{"key":"10.1016\/j.jmig.2026.03.028_bib0046","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1186\/1471-2288-14-135","article-title":"Estimating the sample mean and standard deviation from the sample size, median, range and\/or interquartile range","volume":"14","author":"Wan","year":"2014","journal-title":"BMC Med Res Methodol"},{"key":"10.1016\/j.jmig.2026.03.028_bib0047","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1186\/1471-2288-5-13","article-title":"Estimating the mean and variance from the median, range, and the size of a sample","volume":"5","author":"Hozo","year":"2005","journal-title":"BMC Med Res Methodol"},{"issue":"3","key":"10.1016\/j.jmig.2026.03.028_bib0048","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/0197-2456(86)90046-2","article-title":"Meta-analysis in clinical trials","volume":"7","author":"DerSimonian","year":"1986","journal-title":"Control Clin Trials"},{"issue":"32","key":"10.1016\/j.jmig.2026.03.028_bib0049","first-page":"5","article-title":"Statistical methods in cancer research. Volume I - The analysis of case-control studies","author":"Breslow","year":"1980","journal-title":"IARC Sci Publ"},{"issue":"2","key":"10.1016\/j.jmig.2026.03.028_bib0050","doi-asserted-by":"crossref","first-page":"224","DOI":"10.7326\/0003-4819-107-2-224","article-title":"Meta-analysis in clinical research","volume":"107","author":"L'Abb\u00e9","year":"1987","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.jmig.2026.03.028_bib0051","series-title":"Cochrane handbook for systematic reviews of interventions","author":"Higgins","year":"2019"},{"key":"10.1016\/j.jmig.2026.03.028_bib0052","article-title":"Choosing the route of hysterectomy for benign disease. Committee Opinion No. 701","volume":"129","year":"2017","journal-title":"Obstet Gynecol"},{"issue":"2","key":"10.1016\/j.jmig.2026.03.028_bib0053","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD004993.pub2","article-title":"Total versus subtotal hysterectomy for benign gynaecological conditions","author":"Lethaby","year":"2006","journal-title":"Cochrane Database Syst Rev"},{"issue":"10","key":"10.1016\/j.jmig.2026.03.028_bib0054","first-page":"1017","article-title":"Long term outcome following laparoscopic supracervical hysterectomy","volume":"108","author":"Okaro","year":"2001","journal-title":"BJOG"},{"key":"10.1016\/j.jmig.2026.03.028_bib0055","doi-asserted-by":"crossref","DOI":"10.1016\/j.pec.2024.108478","article-title":"A scoping review of decision regret in non-communicable diseases: The emerging roles of patient-clinician communication, psychological aspects, and medical outcomes","volume":"130","author":"Brera","year":"2025","journal-title":"Patient Educ Couns"}],"container-title":["Journal of Minimally Invasive Gynecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1553465026002013?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1553465026002013?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T01:40:21Z","timestamp":1787276421000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1553465026002013"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":55,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2026,8]]}},"alternative-id":["S1553465026002013"],"URL":"https:\/\/doi.org\/10.1016\/j.jmig.2026.03.028","relation":{},"ISSN":["1553-4650"],"issn-type":[{"value":"1553-4650","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Total Versus Sub-Total Hysterectomy: A Meta-Analysis of Randomized Controlled Trials","name":"articletitle","label":"Article Title"},{"value":"Journal of Minimally Invasive Gynecology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jmig.2026.03.028","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 AAGL. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}