{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T17:14:08Z","timestamp":1782234848903,"version":"3.54.5"},"reference-count":17,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2014,10,1]],"date-time":"2014-10-01T00:00:00Z","timestamp":1412121600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,10,1]],"date-time":"2014-10-01T00:00:00Z","timestamp":1412121600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2016,1,27]],"date-time":"2016-01-27T00:00:00Z","timestamp":1453852800000},"content-version":"vor","delay-in-days":483,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"name":"Board of Doctoral Education at Karolinska Institutet"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Microbiology, Immunology and Infection"],"published-print":{"date-parts":[[2014,10]]},"DOI":"10.1016\/j.jmii.2013.03.009","type":"journal-article","created":{"date-parts":[[2013,5,31]],"date-time":"2013-05-31T22:06:23Z","timestamp":1370037983000},"page":"418-421","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"title":["Incidence of human herpesvirus 6 in clinical samples from Swedish patients with demyelinating diseases"],"prefix":"10.1016","volume":"47","author":[{"given":"Rasmus","family":"Gustafsson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renate","family":"Reitsma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annelie","family":"Str\u00e5lfors","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Lindholm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rayomand","family":"Press","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Fogdell-Hahn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jmii.2013.03.009_bib1","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1126\/science.2876520","article-title":"Isolation of a new virus, HBLV, in patients with lymphoproliferative disorders","volume":"234","author":"Salahuddin","year":"1986","journal-title":"Science"},{"key":"10.1016\/j.jmii.2013.03.009_bib2","doi-asserted-by":"crossref","first-page":"1394","DOI":"10.1038\/nm1297-1394","article-title":"Association of human herpes virus 6 (HHV-6) with multiple sclerosis: increased IgM response to HHV-6 early antigen and detection of serum HHV-6 DNA","volume":"3","author":"Soldan","year":"1997","journal-title":"Nat Med"},{"key":"10.1016\/j.jmii.2013.03.009_bib3","doi-asserted-by":"crossref","first-page":"1365","DOI":"10.1086\/368172","article-title":"Human herpesvirus 6 genome and antigen in acute multiple sclerosis lesions","volume":"187","author":"Goodman","year":"2003","journal-title":"J Infect Dis"},{"key":"10.1016\/j.jmii.2013.03.009_bib4","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/j.jcv.2006.12.003","article-title":"Simultaneous Guillain\u2013Barre syndrome and active human herpesvirus 6 infection in the central nervous system","volume":"38","author":"Galvan","year":"2007","journal-title":"J Clin Virol"},{"key":"10.1016\/j.jmii.2013.03.009_bib5","doi-asserted-by":"crossref","first-page":"1523","DOI":"10.1001\/archneur.61.10.1523","article-title":"Relapsing\u2013remitting multiple sclerosis and human herpesvirus 6 active infection","volume":"61","author":"Alvarez-Lafuente","year":"2004","journal-title":"Arch Neurol"},{"key":"10.1016\/j.jmii.2013.03.009_bib6","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1177\/1352458511428081","article-title":"Anti-HHV-6 IgG titer significantly predicts subsequent relapse risk in multiple sclerosis","volume":"18","author":"Simpson","year":"2012","journal-title":"Mult Scler"},{"key":"10.1016\/j.jmii.2013.03.009_bib7","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1159\/000079936","article-title":"Beta-interferon treatment reduces human herpesvirus-6 viral load in multiple sclerosis relapses but not in remission","volume":"52","author":"Alvarez-Lafuente","year":"2004","journal-title":"Eur Neurol"},{"key":"10.1016\/j.jmii.2013.03.009_bib8","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1136\/jnnp.2007.122549","article-title":"In\u00a0vivo bioactivity of interferon beta in multiple sclerosis patients with neutralizing antibodies is titer dependent","volume":"79","author":"Sominanda","year":"2008","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.jmii.2013.03.009_bib9","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1002\/ana.1032","article-title":"Recommended diagnostic criteria for multiple sclerosis: guidelines from the International Panel on the diagnosis of multiple sclerosis","volume":"50","author":"McDonald","year":"2001","journal-title":"Ann Neurol"},{"key":"10.1016\/j.jmii.2013.03.009_bib10","doi-asserted-by":"crossref","first-page":"1653","DOI":"10.1016\/S0140-6736(05)67665-9","article-title":"Guillain\u2013Barre syndrome","volume":"366","author":"Hughes","year":"2005","journal-title":"Lancet"},{"key":"10.1016\/j.jmii.2013.03.009_bib11","doi-asserted-by":"crossref","first-page":"S21","DOI":"10.1002\/ana.410270707","article-title":"Assessment of current diagnostic criteria for Guillain\u2013Barre syndrome","volume":"27","author":"Asbury","year":"1990","journal-title":"Ann Neurol"},{"key":"10.1016\/j.jmii.2013.03.009_bib12","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1212\/WNL.41.5.617","article-title":"Research criteria for diagnosis of chronic inflammatory demyelinating polyneuropathy (CIDP). Report from an Ad Hoc Subcommittee of the American Academy of Neurology AIDS Task Force","volume":"41","year":"1991","journal-title":"Neurology"},{"key":"10.1016\/j.jmii.2013.03.009_bib13","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1111\/j.0105-2896.2005.00240.x","article-title":"Multiple sclerosis","volume":"204","author":"Hafler","year":"2005","journal-title":"Immunol Rev"},{"key":"10.1016\/j.jmii.2013.03.009_bib14","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.jim.2006.12.012","article-title":"Development and validation of a real time PCR-based bioassay for quantification of neutralizing antibodies against human interferon-beta","volume":"321","author":"Bertolotto","year":"2007","journal-title":"J Immunol Methods"},{"key":"10.1016\/j.jmii.2013.03.009_bib15","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1093\/infdis\/171.2.273","article-title":"Detection of human herpesvirus 6 in plasma of children with primary infection and immunosuppressed patients by polymerase chain reaction","volume":"171","author":"Secchiero","year":"1995","journal-title":"J Infect Dis"},{"key":"10.1016\/j.jmii.2013.03.009_bib16","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1007\/BF01538827","article-title":"Human herpesvirus 6 and human herpesvirus 7 infections in renal transplant recipients and healthy adults in Turkey","volume":"136","author":"Yalcin","year":"1994","journal-title":"Arch Virol"},{"key":"10.1016\/j.jmii.2013.03.009_bib17","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1086\/317651","article-title":"Human herpesvirus 6A DNA is detected frequently in plasma but rarely in peripheral blood leukocytes of patients after bone marrow transplantation","volume":"183","author":"Nitsche","year":"2001","journal-title":"J Infect Dis"}],"container-title":["Journal of Microbiology, Immunology and Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1684118213000625?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1684118213000625?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T13:18:58Z","timestamp":1761657538000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1684118213000625"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,10]]},"references-count":17,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2014,10]]}},"alternative-id":["S1684118213000625"],"URL":"https:\/\/doi.org\/10.1016\/j.jmii.2013.03.009","relation":{},"ISSN":["1684-1182"],"issn-type":[{"value":"1684-1182","type":"print"}],"subject":[],"published":{"date-parts":[[2014,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Incidence of human herpesvirus 6 in clinical samples from Swedish patients with demyelinating diseases","name":"articletitle","label":"Article Title"},{"value":"Journal of Microbiology, Immunology and Infection","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jmii.2013.03.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Published by Elsevier Taiwan LLC.","name":"copyright","label":"Copyright"}]}}