{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T00:18:57Z","timestamp":1787962737284,"version":"build-2784847793"},"reference-count":40,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2018,6,1]],"date-time":"2018-06-01T00:00:00Z","timestamp":1527811200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,6,1]],"date-time":"2018-06-01T00:00:00Z","timestamp":1527811200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2017,9,5]],"date-time":"2017-09-05T00:00:00Z","timestamp":1504569600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"name":"Ministry of Science and Technology","award":["MOST 105-2314-B-002 -139 -MY3"],"award-info":[{"award-number":["MOST 105-2314-B-002 -139 -MY3"]}]},{"name":"Ministry of Science and Technology","award":["105-2320-B-002 -016"],"award-info":[{"award-number":["105-2320-B-002 -016"]}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Microbiology, Immunology and Infection"],"published-print":{"date-parts":[[2018,6]]},"DOI":"10.1016\/j.jmii.2017.08.012","type":"journal-article","created":{"date-parts":[[2017,9,6]],"date-time":"2017-09-06T17:44:35Z","timestamp":1504719875000},"page":"321-331","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"title":["The prevention of coronary arterial abnormalities in Kawasaki disease: A\u00a0meta-analysis of the corticosteroid effectiveness"],"prefix":"10.1016","volume":"51","author":[{"given":"Tsung-Ju","family":"Yang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming-Tai","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun-Yi","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jong-Min","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ping-Ing","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li-Min","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mei-Hwan","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luan-Yin","family":"Chang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jmii.2017.08.012_bib1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jmii.2014.11.001","article-title":"Intravenous immunoglobulin, pharmacogenomics, and Kawasaki disease","volume":"49","author":"Kuo","year":"2016","journal-title":"J Microbiol Immunol Infect"},{"key":"10.1016\/j.jmii.2017.08.012_bib2","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1007\/s00246-014-1016-1","article-title":"Epidemiology of immunoglobulin resistant Kawasaki disease: results from a large, national database","volume":"36","author":"Moffett","year":"2015","journal-title":"Pediatr Cardiol"},{"key":"10.1016\/j.jmii.2017.08.012_bib3","doi-asserted-by":"crossref","first-page":"216","DOI":"10.2188\/jea.JE20110126","article-title":"Epidemiologic features of Kawasaki disease in Japan: results of the 2009\u20132010 nationwide survey","volume":"22","author":"Nakamura","year":"2012","journal-title":"J Epidemiol"},{"key":"10.1016\/j.jmii.2017.08.012_bib4","doi-asserted-by":"crossref","first-page":"2747","DOI":"10.1161\/01.CIR.0000145143.19711.78","article-title":"Diagnosis, treatment, and long-term management of Kawasaki disease: a statement for health professionals from the Committee on Rheumatic Fever, Endocarditis and Kawasaki Disease, Council on Cardiovascular Disease in the Young, American Heart Association","volume":"110","author":"Newburger","year":"2004","journal-title":"Circulation"},{"key":"10.1016\/j.jmii.2017.08.012_bib5","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1542\/peds.96.6.1057","article-title":"The prevention of coronary artery aneurysm in Kawasaki disease: a meta-analysis on the efficacy of aspirin and immunoglobulin treatment","volume":"96","author":"Durongpisitkul","year":"1995","journal-title":"Pediatrics"},{"key":"10.1016\/j.jmii.2017.08.012_bib6","doi-asserted-by":"crossref","first-page":"888","DOI":"10.1016\/S0022-3476(97)70038-6","article-title":"Prevalence of coronary artery abnormalities in Kawasaki disease is highly dependent on gamma globulin dose but independent of salicylate dose","volume":"131","author":"Terai","year":"1997","journal-title":"J Pediatr"},{"key":"10.1016\/j.jmii.2017.08.012_bib7","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1542\/peds.63.2.175","article-title":"Kawasaki disease: effect of treatment on coronary artery involvement","volume":"63","author":"Kato","year":"1979","journal-title":"Pediatrics"},{"key":"10.1016\/j.jmii.2017.08.012_bib8","doi-asserted-by":"crossref","first-page":"1613","DOI":"10.1016\/S0140-6736(11)61930-2","article-title":"Efficacy of immunoglobulin plus prednisolone for prevention of coronary artery abnormalities in severe Kawasaki disease (RAISE study): a randomised, open-label, blinded-endpoints trial","volume":"379","author":"Kobayashi","year":"2012","journal-title":"Lancet"},{"key":"10.1016\/j.jmii.2017.08.012_bib9","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1111\/ped.12317","article-title":"Guidelines for medical treatment of acute Kawasaki disease: report of the Research Committee of the Japanese Society of Pediatric Cardiology and Cardiac Surgery (2012 revised version)","volume":"56","author":"Saji","year":"2014","journal-title":"Pediatr Int"},{"key":"10.1016\/j.jmii.2017.08.012_bib10","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1056\/NEJMoa061235","article-title":"Randomized trial of pulsed corticosteroid therapy for primary treatment of Kawasaki disease","volume":"356","author":"Newburger","year":"2007","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jmii.2017.08.012_bib11","doi-asserted-by":"crossref","first-page":"b2700","DOI":"10.1136\/bmj.b2700","article-title":"The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate healthcare interventions: explanation and elaboration","volume":"339","author":"Liberati","year":"2009","journal-title":"BMJ"},{"key":"10.1016\/j.jmii.2017.08.012_bib12","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1136\/bmj.315.7109.629","article-title":"Bias in meta-analysis detected by a simple, graphical test","volume":"315","author":"Egger","year":"1997","journal-title":"BMJ"},{"key":"10.1016\/j.jmii.2017.08.012_bib13","doi-asserted-by":"crossref","first-page":"3443","DOI":"10.1002\/sim.2380","article-title":"A modified test for small-study effects in meta-analyses of controlled trials with binary endpoints","volume":"25","author":"Harbord","year":"2006","journal-title":"Stat Med"},{"key":"10.1016\/j.jmii.2017.08.012_bib14","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1001\/jama.295.6.676","article-title":"Comparison of two methods to detect publication bias in meta-analysis","volume":"295","author":"Peters","year":"2006","journal-title":"JAMA"},{"key":"10.1016\/j.jmii.2017.08.012_bib15","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1136\/bmj.327.7414.557","article-title":"Measuring inconsistency in meta-analyses","volume":"327","author":"Higgins","year":"2003","journal-title":"BMJ"},{"key":"10.1016\/j.jmii.2017.08.012_bib16","first-page":"719","article-title":"Statistical aspects of the analysis of data from retrospective studies of disease","volume":"22","author":"Mantel","year":"1959","journal-title":"J Natl Cancer Inst"},{"key":"10.1016\/j.jmii.2017.08.012_bib17","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/0197-2456(86)90046-2","article-title":"Meta-analysis in clinical trials","volume":"7","author":"DerSimonian","year":"1986","journal-title":"Control Clin Trials"},{"key":"10.1016\/j.jmii.2017.08.012_bib18","doi-asserted-by":"crossref","first-page":"1156","DOI":"10.1001\/jamapediatrics.2016.2055","article-title":"Coronary artery complication in Kawasaki disease and the importance of early intervention : a systematic review and meta-analysis","volume":"170","author":"Chen","year":"2016","journal-title":"JAMA Pediatr"},{"key":"10.1016\/j.jmii.2017.08.012_bib19","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1016\/j.jpeds.2013.01.022","article-title":"Efficacy of intravenous immunoglobulin combined with prednisolone following resistance to initial intravenous immunoglobulin treatment of acute Kawasaki disease","volume":"163","author":"Kobayashi","year":"2013","journal-title":"J Pediatr"},{"key":"10.1016\/j.jmii.2017.08.012_bib20","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1016\/S0022-3476(99)70169-1","article-title":"Corticosteroids in the treatment of the acute phase of Kawasaki disease","volume":"135","author":"Shinohara","year":"1999","journal-title":"J Pediatr"},{"key":"10.1016\/j.jmii.2017.08.012_bib21","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1016\/j.jpeds.2010.10.031","article-title":"Evaluation of Kawasaki disease risk-scoring systems for intravenous immunoglobulin resistance","volume":"158","author":"Sleeper","year":"2011","journal-title":"J Pediatr"},{"key":"10.1016\/j.jmii.2017.08.012_bib22","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.jmii.2013.06.005","article-title":"Clinical manifestations of Kawasaki disease shock syndrome: a case-control study","volume":"48","author":"Chen","year":"2015","journal-title":"J Microbiol Immunol Infect"},{"key":"10.1016\/j.jmii.2017.08.012_bib23","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1046\/j.1442-200x.2001.01373.x","article-title":"Re-treatment for immune globulin-resistant Kawasaki disease: a comparative study of additional immune globulin and steroid pulse therapy","volume":"43","author":"Hashino","year":"2001","journal-title":"Pediatr Int"},{"key":"10.1016\/j.jmii.2017.08.012_bib24","series-title":"Research committee on Kawasaki disease","author":"Kamiya","year":"1984"},{"key":"10.1016\/j.jmii.2017.08.012_bib25","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1067\/S0022-3476(03)00387-1","article-title":"Effect of corticosteroids in addition to intravenous gamma globulin therapy on serum cytokine levels in the acute phase of Kawasaki disease in children","volume":"143","author":"Okada","year":"2003","journal-title":"J Pediatr"},{"key":"10.1016\/j.jmii.2017.08.012_bib26","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1067\/mpd.2003.191","article-title":"Corticosteroids in the initial treatment of Kawasaki disease: report of a randomized trial","volume":"142","author":"Sundel","year":"2003","journal-title":"J Pediatr"},{"key":"10.1016\/j.jmii.2017.08.012_bib27","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1016\/S0022-3476(98)70229-X","article-title":"Coronary artery dimensions may be misclassified as normal in Kawasaki disease","volume":"133","author":"de Zorzi","year":"1998","journal-title":"J Pediatr"},{"key":"10.1016\/j.jmii.2017.08.012_bib28","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1007\/s00431-003-1386-5","article-title":"Efficacy of intravenous immune globulin therapy combined with dexamethasone for the initial treatment of acute Kawasaki disease","volume":"163","author":"Jibiki","year":"2004","journal-title":"Eur J Pediatr"},{"key":"10.1016\/j.jmii.2017.08.012_bib29","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1016\/j.jpeds.2006.05.025","article-title":"A multicenter prospective randomized trial of corticosteroids in primary therapy for Kawasaki disease: clinical course and coronary artery outcome","volume":"149","author":"Inoue","year":"2006","journal-title":"J Pediatr"},{"key":"10.1016\/j.jmii.2017.08.012_bib30","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1136\/adc.2007.126144","article-title":"Effects of steroid pulse therapy on immunoglobulin-resistant Kawasaki disease","volume":"93","author":"Furukawa","year":"2008","journal-title":"Arch Dis Child"},{"key":"10.1016\/j.jmii.2017.08.012_bib31","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1007\/s00431-007-0642-5","article-title":"Effects of methylprednisolone pulse on cytokine levels in Kawasaki disease patients unresponsive to intravenous immunoglobulin","volume":"167","author":"Miura","year":"2008","journal-title":"Eur J Pediatr"},{"key":"10.1016\/j.jmii.2017.08.012_bib32","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1097\/INF.0b013e3181950b64","article-title":"Risk stratification in the decision to include prednisolone with intravenous immunoglobulin in primary therapy of Kawasaki disease","volume":"28","author":"Kobayashi","year":"2009","journal-title":"Pediatr Infect Dis J"},{"key":"10.1016\/j.jmii.2017.08.012_bib33","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1007\/s00431-008-0727-9","article-title":"Pulse methylprednisolone with gammaglobulin as an initial treatment for acute Kawasaki disease","volume":"168","author":"Okada","year":"2009","journal-title":"Eur J Pediatr"},{"key":"10.1016\/j.jmii.2017.08.012_bib34","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.jjcc.2008.08.002","article-title":"The strategy of immune globulin resistant Kawasaki disease: a comparative study of additional immune globulin and steroid pulse therapy","volume":"53","author":"Ogata","year":"2009","journal-title":"J Cardiol"},{"key":"10.1016\/j.jmii.2017.08.012_bib35","doi-asserted-by":"crossref","first-page":"e17","DOI":"10.1542\/peds.2011-0148","article-title":"Corticosteroid pulse combination therapy for refractory Kawasaki disease: a randomized trial","volume":"129","author":"Ogata","year":"2012","journal-title":"Pediatrics"},{"key":"10.1016\/j.jmii.2017.08.012_bib36","doi-asserted-by":"crossref","first-page":"1260","DOI":"10.3349\/ymj.2014.55.5.1260","article-title":"Clinical outcomes of initial dexamethasone treatment combined with a single high dose of intravenous immunoglobulin for primary treatment of Kawasaki disease","volume":"55","author":"Lim","year":"2014","journal-title":"Yonsei Med J"},{"key":"10.1016\/j.jmii.2017.08.012_bib37","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1007\/s00246-012-0589-9","article-title":"Steroid pulse therapy for children with intravenous immunoglobulin therapy-resistant Kawasaki disease: a prospective study","volume":"34","author":"Teraguchi","year":"2013","journal-title":"Pediatr Cardiol"},{"key":"10.1016\/j.jmii.2017.08.012_bib38","doi-asserted-by":"crossref","first-page":"922","DOI":"10.4103\/0366-6999.179801","article-title":"Corticosteroid therapy might be associated with the development of coronary aneurysm in children with Kawasaki disease","volume":"129","author":"Zhao","year":"2016","journal-title":"Chin Med J"},{"key":"10.1016\/j.jmii.2017.08.012_bib39","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.ijcard.2016.03.017","article-title":"Coronary artery lesions and the increasing incidence of Kawasaki disease resistant to initial immunoglobulin","volume":"214","author":"Kibata","year":"2016","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.jmii.2017.08.012_bib40","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1038\/ng.2220","article-title":"A genome-wide association study identifies three new risk loci for Kawasaki disease","volume":"44","author":"Onouchi","year":"2012","journal-title":"Nat Genet"}],"container-title":["Journal of Microbiology, Immunology and Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1684118217301950?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1684118217301950?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T13:22:57Z","timestamp":1761657777000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1684118217301950"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,6]]},"references-count":40,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2018,6]]}},"alternative-id":["S1684118217301950"],"URL":"https:\/\/doi.org\/10.1016\/j.jmii.2017.08.012","relation":{},"ISSN":["1684-1182"],"issn-type":[{"value":"1684-1182","type":"print"}],"subject":[],"published":{"date-parts":[[2018,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The prevention of coronary arterial abnormalities in Kawasaki disease: A\u00a0meta-analysis of the corticosteroid effectiveness","name":"articletitle","label":"Article Title"},{"value":"Journal of Microbiology, Immunology and Infection","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jmii.2017.08.012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Taiwan Society of Microbiology. Published by Elsevier Taiwan LLC.","name":"copyright","label":"Copyright"}]}}