{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T20:46:27Z","timestamp":1786653987852,"version":"build-2736575974"},"reference-count":34,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T00:00:00Z","timestamp":1785196800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004606","name":"Chang Gung Medical Foundation","doi-asserted-by":"publisher","award":["CMRPG3N0901"],"award-info":[{"award-number":["CMRPG3N0901"]}],"id":[{"id":"10.13039\/501100004606","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004606","name":"Chang Gung Medical Foundation","doi-asserted-by":"publisher","award":["CMRPG3N0902"],"award-info":[{"award-number":["CMRPG3N0902"]}],"id":[{"id":"10.13039\/501100004606","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100020595","name":"National Science and Technology Council","doi-asserted-by":"publisher","award":["113-2314-B-182A-060"],"award-info":[{"award-number":["113-2314-B-182A-060"]}],"id":[{"id":"10.13039\/100020595","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Microbiology, Immunology and Infection"],"published-print":{"date-parts":[[2026,8]]},"DOI":"10.1016\/j.jmii.2026.07.008","type":"journal-article","created":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T15:52:51Z","timestamp":1785858771000},"update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Emerging imipenem resistance in Nocardia infections in Taiwan: a retrospective cohort study at a tertiary teaching hospital"],"prefix":"10.1016","author":[{"given":"Da-Wei","family":"Jhou","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chian-Ya","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2015-355X","authenticated-orcid":false,"given":"Chong Kei","family":"Lao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8922-397X","authenticated-orcid":false,"given":"Nan-Yu","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Po-Yen","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shian-Sen","family":"Shie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chih-Hung","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shih-Hong","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kuo-Rue","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"An-Jing","family":"Kuo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen-Hung","family":"Chung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chih-Jung","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6710-3432","authenticated-orcid":false,"given":"Ting-Shu","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jmii.2026.07.008_bib1","doi-asserted-by":"crossref","DOI":"10.1128\/JCM.01419-17","article-title":"The complexities of Nocardia taxonomy and identification","volume":"56","author":"Conville","year":"2018","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.jmii.2026.07.008_bib2","doi-asserted-by":"crossref","DOI":"10.1128\/cmr.00027-21","article-title":"Updated review on nocardia species: 2006-2021","volume":"35","author":"Traxler","year":"2022","journal-title":"Clin Microbiol Rev"},{"key":"10.1016\/j.jmii.2026.07.008_bib3","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000012436","article-title":"Manifestations and outcomes of Nocardia infections: comparison of immunocompromised and nonimmunocompromised adult patients","volume":"97","author":"Steinbrink","year":"2018","journal-title":"Medicine (Baltim)"},{"key":"10.1016\/j.jmii.2026.07.008_bib4","doi-asserted-by":"crossref","DOI":"10.1016\/j.jtct.2022.12.004","article-title":"Risk factors and outcomes of nocardiosis in hematopoietic stem cell transplantation recipients","volume":"29","author":"Yetmar","year":"2023","journal-title":"Transplant Cell Ther"},{"key":"10.1016\/j.jmii.2026.07.008_bib5","doi-asserted-by":"crossref","DOI":"10.1111\/tid.13753","article-title":"Recurrent nocardiosis in solid organ transplant recipients: an evaluation of secondary prophylaxis","volume":"23","author":"Yetmar","year":"2021","journal-title":"Transpl Infect Dis"},{"key":"10.1016\/j.jmii.2026.07.008_bib6","doi-asserted-by":"crossref","first-page":"542","DOI":"10.3389\/fmicb.2016.00542","article-title":"Shortcomings of the commercial MALDI-TOF MS database and use of MLSA as an arbiter in the identification of Nocardia species","volume":"7","author":"Carrasco","year":"2016","journal-title":"Front Microbiol"},{"key":"10.1016\/j.jmii.2026.07.008_bib7","series-title":"CLSI standard M24","article-title":"Susceptibility testing of mycobacteria, Nocardia spp., and other aerobic actinomycetes","year":"2018"},{"key":"10.1016\/j.jmii.2026.07.008_bib8","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1007\/s10482-012-9780-5","article-title":"A genome sequence-based approach to taxonomy of the genus Nocardia","volume":"102","author":"Tamura","year":"2012","journal-title":"Antonie Leeuwenhoek"},{"key":"10.1016\/j.jmii.2026.07.008_bib9","doi-asserted-by":"crossref","first-page":"1755","DOI":"10.1007\/s10482-019-01296-2","article-title":"Molecular identification and phylogenetic relationships of clinical Nocardia isolates","volume":"112","author":"Wei","year":"2019","journal-title":"Antonie Leeuwenhoek"},{"key":"10.1016\/j.jmii.2026.07.008_bib10","doi-asserted-by":"crossref","first-page":"4525","DOI":"10.1128\/JCM.00883-10","article-title":"Phylogeny and identification of Nocardia species on the basis of multilocus sequence analysis","volume":"48","author":"McTaggart","year":"2010","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.jmii.2026.07.008_bib11","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1093\/cid\/ciw241","article-title":"Nocardia infection in solid organ transplant recipients: a multicenter European case-control study","volume":"63","author":"Coussement","year":"2016","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.jmii.2026.07.008_bib12","doi-asserted-by":"crossref","first-page":"1367","DOI":"10.1093\/cid\/ciz1008","article-title":"Revision and update of the consensus definitions of invasive fungal disease from the European organization for research and treatment of cancer and the mycoses study group education and research consortium","volume":"71","author":"Donnelly","year":"2020","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.jmii.2026.07.008_bib13","doi-asserted-by":"crossref","first-page":"2109","DOI":"10.1016\/j.jfma.2022.06.011","article-title":"Clinical manifestations and antimicrobial susceptibility of Nocardia species at a tertiary hospital in Taiwan, 2011-2020","volume":"121","author":"Lao","year":"2022","journal-title":"J Formos Med Assoc"},{"key":"10.1016\/j.jmii.2026.07.008_bib14","doi-asserted-by":"crossref","DOI":"10.1016\/j.cmi.2018.06.014","article-title":"Identification of Nocardia species from clinical isolates using MALDI-TOF mass spectrometry","volume":"24","author":"Marin","year":"2018","journal-title":"Clin Microbiol Infect"},{"key":"10.1016\/j.jmii.2026.07.008_bib15","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1128\/JCM.44.2.536-546.2006","article-title":"Use of PCR-restriction enzyme pattern analysis and sequencing database for hsp65 gene-based identification of Nocardia species","volume":"44","author":"Rodr\u00edguez-Nava","year":"2006","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.jmii.2026.07.008_bib16","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1128\/AAC.01531-13","article-title":"Susceptibility profiles of Nocardia isolates based on current taxonomy","volume":"58","author":"Schlaberg","year":"2014","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.jmii.2026.07.008_bib17","doi-asserted-by":"crossref","first-page":"2760","DOI":"10.1128\/JCM.00155-06","article-title":"Analysis of secA1 gene sequences for identification of Nocardia species","volume":"44","author":"Conville","year":"2006","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.jmii.2026.07.008_bib18","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0002573","article-title":"Molecular identification of Nocardia isolates from clinical samples and an overview of human nocardiosis in Brazil","volume":"7","author":"Baio","year":"2013","journal-title":"PLoS Neglected Trop Dis"},{"key":"10.1016\/j.jmii.2026.07.008_bib19","doi-asserted-by":"crossref","first-page":"W293","DOI":"10.1093\/nar\/gkab301","article-title":"Interactive tree of life (iTOL) v5: an online tool for phylogenetic tree display and annotation","volume":"49","author":"Letunic","year":"2021","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.jmii.2026.07.008_bib20","doi-asserted-by":"crossref","DOI":"10.1093\/molbev\/msae263","article-title":"MEGA12: molecular evolutionary genetic analysis version 12 for adaptive and green computing","volume":"41","author":"Kumar","year":"2024","journal-title":"Mol Biol Evol"},{"key":"10.1016\/j.jmii.2026.07.008_bib21","doi-asserted-by":"crossref","DOI":"10.1093\/ofid\/ofw208","article-title":"Nocardiosis in the tropical Northern Territory of Australia, 1997-2014","volume":"3","author":"McGuinness","year":"2016","journal-title":"Open Forum Infect Dis"},{"key":"10.1016\/j.jmii.2026.07.008_bib22","first-page":"754","article-title":"Epidemiology and susceptibility to antimicrobial agents of the main Nocardia species in Spain","volume":"72","author":"Valdezate","year":"2017","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.jmii.2026.07.008_bib23","doi-asserted-by":"crossref","DOI":"10.1128\/AAC.01868-19","article-title":"Retrospective analysis of antimicrobial susceptibility profiles of Nocardia species from a tertiary hospital and reference laboratory, 2011 to 2017","volume":"64","author":"Hamdi","year":"2020","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.jmii.2026.07.008_bib24","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/j.cmi.2018.06.013","article-title":"Antibiotic susceptibility testing and species identification of Nocardia isolates: a retrospective analysis of data from a French expert laboratory, 2010-2015","volume":"25","author":"Lebeaux","year":"2019","journal-title":"Clin Microbiol Infect"},{"key":"10.1016\/j.jmii.2026.07.008_bib25","doi-asserted-by":"crossref","first-page":"2417","DOI":"10.3201\/eid2912.230673","article-title":"Invasive Nocardia infections across distinct geographic regions, United States","volume":"29","author":"Gupta","year":"2023","journal-title":"Emerg Infect Dis"},{"key":"10.1016\/j.jmii.2026.07.008_bib26","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1111\/j.1469-0691.2009.02950.x","article-title":"Clinical and microbiological characteristics of nocardiosis including those caused by emerging Nocardia species in Taiwan, 1998\u20132008","volume":"16","author":"Tan","year":"2010","journal-title":"Clin Microbiol Infect"},{"key":"10.1016\/j.jmii.2026.07.008_bib27","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1016\/j.jmii.2022.11.002","article-title":"Clinical manifestations and outcome of nocardiosis and antimicrobial susceptibility of Nocardia species in southern Taiwan, 2011-2021","volume":"56","author":"Yang","year":"2023","journal-title":"J Microbiol Immunol Infect"},{"key":"10.1016\/j.jmii.2026.07.008_bib28","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.1007\/s10096-011-1227-9","article-title":"Clinical and microbiological characteristics of infections caused by various Nocardia species in Taiwan: a multicenter study from 1998 to 2010","volume":"30","author":"Liu","year":"2011","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"10.1016\/j.jmii.2026.07.008_bib29","doi-asserted-by":"crossref","first-page":"2257","DOI":"10.1128\/JCM.00133-07","article-title":"Organisms designated as Nocardia asteroides drug pattern type VI are members of the species Nocardia cyriacigeorgica","volume":"45","author":"Conville","year":"2007","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.jmii.2026.07.008_bib30","doi-asserted-by":"crossref","first-page":"e53","DOI":"10.1093\/cid\/ciae643","article-title":"State-of-the-art review: modern approach to nocardiosis\u2014diagnosis, management, and uncertainties","volume":"80","author":"Yetmar","year":"2025","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.jmii.2026.07.008_bib31","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1128\/AAC.02770-14","article-title":"Antimicrobial susceptibility among clinical Nocardia species identified by multilocus sequence analysis","volume":"59","author":"McTaggart","year":"2015","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.jmii.2026.07.008_bib32","article-title":"Nocardia spp. the Sanford guide to antimicrobial therapy","author":"Gilbert","year":"2026","journal-title":"Sperryville, VA: Antimicrobial Therapy, Inc"},{"key":"10.1016\/j.jmii.2026.07.008_bib33","doi-asserted-by":"crossref","DOI":"10.1128\/aac.01890-21","article-title":"Nocardiosis in Japan: a multicentric retrospective cohort Study","volume":"66","author":"Takamatsu","year":"2022","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.jmii.2026.07.008_bib34","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1128\/CMR.19.2.259-282.2006","article-title":"Clinical and laboratory features of the Nocardia spp. based on current molecular taxonomy","volume":"19","author":"Brown-Elliott","year":"2006","journal-title":"Clin Microbiol Rev"}],"container-title":["Journal of Microbiology, Immunology and Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1684118226000940?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1684118226000940?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T20:09:33Z","timestamp":1786651773000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1684118226000940"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":34,"alternative-id":["S1684118226000940"],"URL":"https:\/\/doi.org\/10.1016\/j.jmii.2026.07.008","relation":{},"ISSN":["1684-1182"],"issn-type":[{"value":"1684-1182","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Emerging imipenem resistance in Nocardia infections in Taiwan: a retrospective cohort study at a tertiary teaching hospital","name":"articletitle","label":"Article Title"},{"value":"Journal of Microbiology, Immunology and Infection","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jmii.2026.07.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Taiwan Society of Microbiology. Published by Elsevier Taiwan LLC.","name":"copyright","label":"Copyright"}]}}