{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T08:47:19Z","timestamp":1789721239637,"version":"4.0.1"},"reference-count":69,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"vor","delay-in-days":366,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100005492","name":"Stanford University","doi-asserted-by":"publisher","award":["2020"],"award-info":[{"award-number":["2020"]}],"id":[{"id":"10.13039\/100005492","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jmdjournal.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Molecular Diagnostics"],"published-print":{"date-parts":[[2023,4]]},"DOI":"10.1016\/j.jmoldx.2023.01.002","type":"journal-article","created":{"date-parts":[[2023,1,23]],"date-time":"2023-01-23T11:59:26Z","timestamp":1674475166000},"page":"197-210","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"title":["Point-of-Care Testing of Enzyme Polymorphisms for Predicting Hypnotizability and Postoperative Pain"],"prefix":"10.1016","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9267-4015","authenticated-orcid":false,"given":"Dana L.","family":"Cortade","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7499-2837","authenticated-orcid":false,"given":"Jessie","family":"Markovits","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Spiegel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8420-9554","authenticated-orcid":false,"given":"Shan X.","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jmoldx.2023.01.002_bib1","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1080\/00207144.2021.1920330","article-title":"Hypnosis and the alleviation of clinical pain: a comprehensive meta-analysis","volume":"69","author":"Milling","year":"2021","journal-title":"Int J Clin Exp Hypn"},{"key":"10.1016\/j.jmoldx.2023.01.002_bib2","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1080\/00207147408413004","article-title":"The stability of hypnotic susceptibility: a longitudinal study","volume":"22","author":"Morgan","year":"1974","journal-title":"Int J Clin Exp Hypn"},{"key":"10.1016\/j.jmoldx.2023.01.002_bib3","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1037\/0022-3514.56.2.289","article-title":"On the degree of stability of measured hypnotizability over a 25-year period","volume":"56","author":"Piccione","year":"1989","journal-title":"J Pers Soc Psychol"},{"key":"10.1016\/j.jmoldx.2023.01.002_bib4","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1080\/00029157.2002.10403480","article-title":"A historical overview of hypnotizability assessment","volume":"44","author":"Council","year":"2002","journal-title":"Am J Clin Hypn"},{"key":"10.1016\/j.jmoldx.2023.01.002_bib5","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1037\/h0034854","article-title":"The heritability of hypnotic susceptibility in twins","volume":"82","author":"Morgan","year":"1973","journal-title":"J Abnorm Psychol"},{"key":"10.1016\/j.jmoldx.2023.01.002_bib6","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1080\/00207141003760827","article-title":"Association between hypnotizability and the catechol-O-methyltransferase (COMT) polymorphism","volume":"58","author":"Szekely","year":"2010","journal-title":"Int J Clin Exp Hypn"},{"key":"10.1016\/j.jmoldx.2023.01.002_bib7","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1080\/00207144.2014.931177","article-title":"Carriers of the COMT Met\/Met\u00a0allele have higher degrees of hypnotizability, provided that they have good attentional control: a case of gene-trait interaction","volume":"62","author":"Rominger","year":"2014","journal-title":"Int J Clin Exp Hypn"},{"key":"10.1016\/j.jmoldx.2023.01.002_bib8","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1080\/00207144.2018.1396120","article-title":"COMT genotype and sensory and sensorimotor gating in high and low hypnotizable subjects","volume":"66","author":"Storozheva","year":"2018","journal-title":"Int J Clin Exp Hypn"},{"key":"10.1016\/j.jmoldx.2023.01.002_bib9","doi-asserted-by":"crossref","first-page":"1943","DOI":"10.1038\/sj.npp.1300542","article-title":"The catechol-O-methyltransferase polymorphism: relations to the tonic\u2013phasic dopamine hypothesis and neuropsychiatric phenotypes","volume":"29","author":"Bilder","year":"2004","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.jmoldx.2023.01.002_bib10","first-page":"4083","article-title":"Brain activity and functional connectivity associated with hypnosis","volume":"27","author":"Jiang","year":"2017","journal-title":"Cereb Cortex"},{"key":"10.1016\/j.jmoldx.2023.01.002_bib11","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1080\/00207140590961295","article-title":"Attention and hypnosis: neural substrates and genetic associations of two converging processes","volume":"53","author":"Raz","year":"2005","journal-title":"Int J Clin Exp Hypn"},{"key":"10.1016\/j.jmoldx.2023.01.002_bib12","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1162\/089892902760191117","article-title":"Hypnosis modulates activity in brain structures involved in the regulation of consciousness","volume":"14","author":"Rainville","year":"2002","journal-title":"J Cogn Neurosci"},{"key":"10.1016\/j.jmoldx.2023.01.002_bib13","doi-asserted-by":"crossref","first-page":"669","DOI":"10.2217\/pgs.09.13","article-title":"Variation in the COMT gene: implications for pain perception and pain treatment","volume":"10","author":"Andersen","year":"2009","journal-title":"Pharmacogenomics"},{"key":"10.1016\/j.jmoldx.2023.01.002_bib14","doi-asserted-by":"crossref","first-page":"277","DOI":"10.2217\/pgs.13.248","article-title":"Genetics of pain perception, COMT and postoperative pain management in children","volume":"15","author":"Sadhasivam","year":"2014","journal-title":"Pharmacogenomics"},{"key":"10.1016\/j.jmoldx.2023.01.002_bib15","doi-asserted-by":"crossref","first-page":"181","DOI":"10.2217\/pgs-2019-0141","article-title":"OPRM1 and COMT polymorphisms: implications on postoperative acute, chronic and experimental pain after cardiac surgery","volume":"21","author":"Matic","year":"2020","journal-title":"Pharmacogenomics"},{"key":"10.1016\/j.jmoldx.2023.01.002_bib16","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1086\/425589","article-title":"Functional analysis of genetic variation in catechol-O-methyltransferase (COMT): effects on mRNA, protein, and enzyme activity in postmortem human brain","volume":"75","author":"Chen","year":"2004","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.jmoldx.2023.01.002_bib17","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1093\/hmg\/ddi013","article-title":"Genetic basis for individual variations in pain perception and the development of a chronic pain condition","volume":"14","author":"Diatchenko","year":"2005","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.jmoldx.2023.01.002_bib18","doi-asserted-by":"crossref","first-page":"1930","DOI":"10.1126\/science.1131262","article-title":"Human catechol-O-methyltransferase haplotypes modulate protein expression by altering mRNA secondary structure","volume":"314","author":"Nackley","year":"2006","journal-title":"Science"},{"key":"10.1016\/j.jmoldx.2023.01.002_bib19","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1007\/978-1-60327-323-7_28","article-title":"Assessing potential functionality of catechol-O-methyltransferase (COMT) polymorphisms associated with pain sensitivity and temporomandibular joint disorders","volume":"617","author":"Nackley","year":"2010","journal-title":"Methods Mol Biol"},{"key":"10.1016\/j.jmoldx.2023.01.002_bib20","doi-asserted-by":"crossref","first-page":"6201","DOI":"10.1093\/nar\/gkr165","article-title":"Disruptive mRNA folding increases translational efficiency of catechol-O-methyltransferase variant","volume":"39","author":"Tsao","year":"2011","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.jmoldx.2023.01.002_bib21","doi-asserted-by":"crossref","first-page":"2619","DOI":"10.1007\/s00429-019-01924-7","article-title":"Impact of COMT haplotypes on functional connectivity density and its association with the gene expression of dopamine receptors","volume":"224","author":"Tang","year":"2019","journal-title":"Brain Struct Funct"},{"key":"10.1016\/j.jmoldx.2023.01.002_bib22","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/B978-0-12-381326-8.00010-7","article-title":"Catechol-O-methyltransferase and pain","volume":"95","author":"Kambur","year":"2010","journal-title":"Int Rev Neurobiol"},{"key":"10.1016\/j.jmoldx.2023.01.002_bib23","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1002\/j.1532-2149.2012.00153.x","article-title":"Pain sensitivity in fibromyalgia is associated with catechol-O-methyltransferase (COMT) gene","volume":"17","author":"Mart\u00ednez-Jauand","year":"2013","journal-title":"Eur J Pain"},{"key":"10.1016\/j.jmoldx.2023.01.002_bib24","doi-asserted-by":"crossref","first-page":"e3374","DOI":"10.1002\/jgm.3374","article-title":"Genetic variation in catechol-O-methyltransferase is associated with individual differences in conditioned pain modulation in healthy subjects","volume":"23","author":"Korczeniewska","year":"2021","journal-title":"J Gene Med"},{"key":"10.1016\/j.jmoldx.2023.01.002_bib25","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1080\/00365513.2019.1576920","article-title":"Association of COMT gene variability with pain intensity in patients after total hip replacement","volume":"79","author":"Machoy-Mokrzy\u0144ska","year":"2019","journal-title":"Scand J Clin Lab Invest"},{"key":"10.1016\/j.jmoldx.2023.01.002_bib26","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1038\/s41397-019-0131-z","article-title":"OPRM1, OPRK1, and COMT genetic polymorphisms associated with opioid effects on experimental pain: a randomized, double-blind, placebo-controlled study","volume":"20","author":"Ho","year":"2020","journal-title":"Pharmacogenomics J"},{"key":"10.1016\/j.jmoldx.2023.01.002_bib27","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1213\/ANE.0000000000000563","article-title":"COMT gene haplotypes are closely associated with postoperative fentanyl dose in patients","volume":"120","author":"Zhang","year":"2015","journal-title":"Anesth Analg"},{"key":"10.1016\/j.jmoldx.2023.01.002_bib28","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1177\/1099800416680474","article-title":"OPRM1 and COMT gene\u2013gene interaction is associated with postoperative pain and opioid consumption after orthopedic trauma","volume":"19","author":"Khalil","year":"2017","journal-title":"Biol Res Nurs"},{"key":"10.1016\/j.jmoldx.2023.01.002_bib29","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/j.jad.2017.12.044","article-title":"Catechol O-methyltransferase (COMT) functional haplotype is associated with recurrence of affective symptoms: a prospective birth cohort study","volume":"229","author":"Koike","year":"2018","journal-title":"J Affect Disord"},{"key":"10.1016\/j.jmoldx.2023.01.002_bib30","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1097\/YIC.0b013e328338b884","article-title":"The impact of catechol-O-methyltransferase SNPs and haplotypes on treatment response phenotypes in major depressive disorder: a case\u2013control association study","volume":"25","author":"Kocabas","year":"2010","journal-title":"Int Clin Psychopharmacol"},{"key":"10.1016\/j.jmoldx.2023.01.002_bib31","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/j.euroneuro.2011.08.007","article-title":"The impact of COMT gene polymorphisms on suicidality in treatment resistant major depressive disorder\u2014a European Multicenter Study","volume":"22","author":"Schosser","year":"2012","journal-title":"Eur Neuropsychopharmacol"},{"key":"10.1016\/j.jmoldx.2023.01.002_bib32","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1515\/REVNEURO.2006.17.3.359","article-title":"The effects of catechol O-methyltransferase genotype on brain activation elicited by affective stimuli and cognitive tasks","volume":"17","author":"Heinz","year":"2006","journal-title":"Rev Neurosci"},{"key":"10.1016\/j.jmoldx.2023.01.002_bib33","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1080\/00048670802607238","article-title":"Dopamine vs noradrenaline: inverted-U effects and ADHD theories","volume":"43","author":"Levy","year":"2009","journal-title":"Aust N Z J Psychiatry"},{"key":"10.1016\/j.jmoldx.2023.01.002_bib34","doi-asserted-by":"crossref","first-page":"e113","DOI":"10.1016\/j.biopsych.2011.03.028","article-title":"Inverted-U-shaped dopamine actions on human working memory and cognitive control","volume":"69","author":"Cools","year":"2011","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.jmoldx.2023.01.002_bib35","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1038\/nn1846","article-title":"Inverted-U dopamine D1 receptor actions on prefrontal neurons engaged in working memory","volume":"10","author":"Vijayraghavan","year":"2007","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.jmoldx.2023.01.002_bib36","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1016\/j.biopsych.2008.05.015","article-title":"The dual-state theory of prefrontal cortex dopamine function with relevance to catechol-O-methyltransferase genotypes and schizophrenia","volume":"64","author":"Durstewitz","year":"2008","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.jmoldx.2023.01.002_bib37","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1007\/s10038-007-0200-z","article-title":"SNPs in disease gene mapping, medicinal drug development and evolution","volume":"52","author":"Shastry","year":"2007","journal-title":"J Hum Genet"},{"key":"10.1016\/j.jmoldx.2023.01.002_bib38","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1097\/00041444-200206000-00004","article-title":"A nanobiotechnology roadmap for high-throughput single nucleotide polymorphism analysis","volume":"12","author":"Galvin","year":"2002","journal-title":"Psychiatr Genet"},{"key":"10.1016\/j.jmoldx.2023.01.002_bib39","series-title":"A Point-of-Care Testing System with Giant Magnetoresistive Biosensors","author":"Yao","year":"2020"},{"key":"10.1016\/j.jmoldx.2023.01.002_bib40","doi-asserted-by":"crossref","first-page":"113982","DOI":"10.1016\/j.bios.2022.113982","article-title":"An automated and mobile magnetoresistive biosensor system for early hepatocellular carcinoma diagnosis","volume":"202","author":"Yao","year":"2022","journal-title":"Biosens Bioelectron"},{"key":"10.1016\/j.jmoldx.2023.01.002_bib41","doi-asserted-by":"crossref","first-page":"1327","DOI":"10.1038\/nm.2032","article-title":"Matrix-insensitive protein assays push the limits of biosensors in medicine","volume":"15","author":"Gaster","year":"2009","journal-title":"Nat Med"},{"key":"10.1016\/j.jmoldx.2023.01.002_bib42","doi-asserted-by":"crossref","first-page":"20637","DOI":"10.1073\/pnas.0810822105","article-title":"Multiplex protein assays based on real-time magnetic nanotag sensing","volume":"105","author":"Osterfeld","year":"2008","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.jmoldx.2023.01.002_bib43","doi-asserted-by":"crossref","first-page":"2764","DOI":"10.1002\/anie.200806266","article-title":"A detection system based on giant magnetoresistive sensors and high-moment magnetic nanoparticles demonstrates zeptomole sensitivity: potential for personalized medicine","volume":"48","author":"Srinivasan","year":"2009","journal-title":"Angew Chem Int Ed Engl"},{"key":"10.1016\/j.jmoldx.2023.01.002_bib44","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.bios.2016.04.046","article-title":"Portable, one-step, and rapid GMR biosensor platform with smartphone interface","volume":"85","author":"Choi","year":"2016","journal-title":"Biosens Bioelectron"},{"key":"10.1016\/j.jmoldx.2023.01.002_bib45","doi-asserted-by":"crossref","first-page":"15615","DOI":"10.1038\/s41598-019-52147-z","article-title":"An automated, quantitative, and multiplexed assay suitable for point-of-care hepatitis B virus diagnostics","volume":"9","author":"Gani","year":"2019","journal-title":"Sci Rep"},{"key":"10.1016\/j.jmoldx.2023.01.002_bib46","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.nano.2018.11.007","article-title":"Magneto-nanosensor smartphone platform for the detection of HIV and leukocytosis at point-of-care","volume":"16","author":"Ng","year":"2019","journal-title":"Nanomed Nanotechnol Biol Med"},{"key":"10.1016\/j.jmoldx.2023.01.002_bib47","doi-asserted-by":"crossref","first-page":"3705","DOI":"10.1016\/j.bios.2011.02.013","article-title":"GMR sensors: magnetoresistive behaviour optimization for biological detection by means of superparamagnetic nanoparticles","volume":"26","author":"Manteca","year":"2011","journal-title":"Biosens Bioelectron"},{"key":"10.1016\/j.jmoldx.2023.01.002_bib48","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1016\/j.bios.2018.09.050","article-title":"Quantification of cDNA on GMR biosensor array towards point-of-care gene expression analysis","volume":"130","author":"Ravi","year":"2019","journal-title":"Biosens Bioelectron"},{"key":"10.1016\/j.jmoldx.2023.01.002_bib49","doi-asserted-by":"crossref","first-page":"114086","DOI":"10.1016\/j.bios.2022.114086","article-title":"A GMR-based assay for quantification of the human response to influenza","volume":"205","author":"Ravi","year":"2022","journal-title":"Biosens Bioelectron"},{"key":"10.1016\/j.jmoldx.2023.01.002_bib50","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1016\/j.bios.2013.09.026","article-title":"Magnetoresistive sensor for real-time single nucleotide polymorphism genotyping","volume":"52","author":"Rizzi","year":"2014","journal-title":"Biosens Bioelectron"},{"key":"10.1016\/j.jmoldx.2023.01.002_bib51","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1093\/clinchem\/hvaa307","article-title":"Giant magnetoresistive nanosensor analysis of circulating tumor DNA epidermal growth factor receptor mutations for diagnosis and therapy response monitoring","volume":"67","author":"Nesvet","year":"2021","journal-title":"Clin Chem"},{"key":"10.1016\/j.jmoldx.2023.01.002_bib52","doi-asserted-by":"crossref","first-page":"2131","DOI":"10.1039\/D2LC00233G","article-title":"From saliva to SNP: non-invasive, point-of-care genotyping for precision medicine applications using recombinase polymerase amplification and giant magnetoresistive nanosensors","volume":"22","author":"de Olazarra","year":"2022","journal-title":"Lab Chip"},{"key":"10.1016\/j.jmoldx.2023.01.002_bib53","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.bios.2018.10.018","article-title":"Highly sensitive detection of DNA hypermethylation in melanoma cancer cells","volume":"124\u2013125","author":"Nesvet","year":"2019","journal-title":"Biosens Bioelectron"},{"key":"10.1016\/j.jmoldx.2023.01.002_bib54","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1080\/00207144.2021.1836646","article-title":"The hypnotic induction profile (HIP) in clinical practice and research","volume":"69","author":"Alexander","year":"2021","journal-title":"Int J Clin Exp Hypn"},{"key":"10.1016\/j.jmoldx.2023.01.002_bib55","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1080\/00207147608416210","article-title":"Psychometric analysis of the hypnotic induction profile","volume":"24","author":"Spiegel","year":"1976","journal-title":"Int J Clin Exp Hypn"},{"key":"10.1016\/j.jmoldx.2023.01.002_bib56","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1080\/00207144.2021.1827937","article-title":"Testing hypnotizability by phone: development and validation of the remote hypnotic induction profile (rHIP)","volume":"69","author":"Kittle","year":"2021","journal-title":"Int J Clin Exp Hypn"},{"key":"10.1016\/j.jmoldx.2023.01.002_bib57","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1136\/rapm-2022-103493","article-title":"Effects of hypnosis versus enhanced standard of care on postoperative opioid use after total knee arthroplasty: the HYPNO-TKA randomized clinical trial","volume":"47","author":"Markovits","year":"2022","journal-title":"Reg Anesth Pain Med"},{"key":"10.1016\/j.jmoldx.2023.01.002_bib58","doi-asserted-by":"crossref","first-page":"1064","DOI":"10.1001\/archgenpsychiatry.2011.2190","article-title":"Functional brain basis of hypnotizability","volume":"69","author":"Hoeft","year":"2012","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.jmoldx.2023.01.002_bib59","doi-asserted-by":"crossref","first-page":"2905","DOI":"10.1038\/s41467-021-23185-x","article-title":"A rapid, accurate, scalable, and portable testing system for COVID-19 diagnosis","volume":"12","author":"Xun","year":"2021","journal-title":"Nat Commun"},{"key":"10.1016\/j.jmoldx.2023.01.002_bib60","doi-asserted-by":"crossref","first-page":"1368","DOI":"10.1016\/j.pain.2013.04.028","article-title":"Pain modality- and sex-specific effects of COMT genetic functional variants","volume":"154","author":"Belfer","year":"2013","journal-title":"Pain"},{"key":"10.1016\/j.jmoldx.2023.01.002_bib61","doi-asserted-by":"crossref","first-page":"e61839","DOI":"10.1371\/journal.pone.0061839","article-title":"Sexually dimorphic effects of catechol-O-methyltransferase (COMT) inhibition on dopamine metabolism in multiple brain regions","volume":"8","author":"Laatikainen","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.jmoldx.2023.01.002_bib62","doi-asserted-by":"crossref","first-page":"578","DOI":"10.3389\/fnhum.2017.00578","article-title":"COMT Val158Met polymorphism exerts sex-dependent effects on fMRI measures of brain function","volume":"11","author":"Elton","year":"2017","journal-title":"Front Hum Neurosci"},{"key":"10.1016\/j.jmoldx.2023.01.002_bib63","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1080\/00207144.2018.1396128","article-title":"Polymorphism of opioid receptors \u03bc1 in highly hypnotizable subjects","volume":"66","author":"Presciuttini","year":"2018","journal-title":"Int J Clin Exp Hypn"},{"key":"10.1016\/j.jmoldx.2023.01.002_bib64","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1080\/13546805.2010.503048","article-title":"Dissociative tendencies and individual differences in high hypnotic suggestibility","volume":"16","author":"Terhune","year":"2011","journal-title":"Cogn Neuropsychiatry"},{"key":"10.1016\/j.jmoldx.2023.01.002_bib65","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.concog.2015.11.001","article-title":"Patterns of hypnotic response, revisited","volume":"38","author":"Kihlstrom","year":"2015","journal-title":"Conscious Cogn"},{"key":"10.1016\/j.jmoldx.2023.01.002_bib66","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1016\/j.concog.2015.01.018","article-title":"Discrete response patterns in the upper range of hypnotic suggestibility: a latent profile analysis","volume":"33","author":"Terhune","year":"2015","journal-title":"Conscious Cogn"},{"key":"10.1016\/j.jmoldx.2023.01.002_bib67","doi-asserted-by":"crossref","first-page":"1240","DOI":"10.1126\/science.1078546","article-title":"COMT val158met genotype affects \u03bc-opioid neurotransmitter responses to a pain stressor","volume":"299","author":"Zubieta","year":"2003","journal-title":"Science"},{"key":"10.1016\/j.jmoldx.2023.01.002_bib68","doi-asserted-by":"crossref","first-page":"e6016","DOI":"10.1371\/journal.pone.0006016","article-title":"Increased sensitivity to thermal pain following a single opiate dose is influenced by the COMT val(158)met polymorphism","volume":"4","author":"Jensen","year":"2009","journal-title":"PLoS One"},{"key":"10.1016\/j.jmoldx.2023.01.002_bib69","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1097\/00006842-197911000-00003","article-title":"Demographic and affective covariates of pain","volume":"41","author":"Garron","year":"1979","journal-title":"Psychosom Med"}],"container-title":["The Journal of Molecular Diagnostics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S152515782300003X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S152515782300003X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T18:17:30Z","timestamp":1761502650000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S152515782300003X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4]]},"references-count":69,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2023,4]]}},"alternative-id":["S152515782300003X"],"URL":"https:\/\/doi.org\/10.1016\/j.jmoldx.2023.01.002","relation":{},"ISSN":["1525-1578"],"issn-type":[{"value":"1525-1578","type":"print"}],"subject":[],"published":{"date-parts":[[2023,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Point-of-Care Testing of Enzyme Polymorphisms for Predicting Hypnotizability and Postoperative Pain","name":"articletitle","label":"Article Title"},{"value":"The Journal of Molecular Diagnostics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jmoldx.2023.01.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Association for Molecular Pathology and American Society for Investigative Pathology. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}