{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T15:50:24Z","timestamp":1787932224731,"version":"build-2784847793"},"reference-count":61,"publisher":"National University of Health Sciences","issue":"2","license":[{"start":{"date-parts":[[2012,2,1]],"date-time":"2012-02-01T00:00:00Z","timestamp":1328054400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Manipulative and Physiological Therapeutics"],"published-print":{"date-parts":[[2012,2]]},"DOI":"10.1016\/j.jmpt.2011.12.002","type":"journal-article","created":{"date-parts":[[2012,1,16]],"date-time":"2012-01-16T20:11:59Z","timestamp":1326744719000},"page":"110-120","source":"Crossref","is-referenced-by-count":47,"title":["Effect of Thumb Joint Mobilization on Pressure Pain Threshold in Elderly Patients with Thumb Carpometacarpal Osteoarthritis"],"prefix":"10.67400","volume":"35","author":[{"given":"Jorge H.","family":"Villafa\u00f1e","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guillermo B.","family":"Silva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josue","family":"Fernandez-Carnero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"57152","reference":[{"key":"10.1016\/j.jmpt.2011.12.002_bb0005","doi-asserted-by":"crossref","first-page":"8823","DOI":"10.4076\/1757-1626-2-8823","article-title":"A patient with osteoarthritis and cardiovascular disease presenting with bilateral hip pain: a case report","volume":"2","author":"Yanow","year":"2009","journal-title":"Cases J"},{"key":"10.1016\/j.jmpt.2011.12.002_bb0010","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.jht.2008.09.002","article-title":"Exercise and hand osteoarthritis symptomatology: a controlled crossover trial","volume":"22","author":"Rogers","year":"2009","journal-title":"J Hand Ther"},{"key":"10.1016\/j.jmpt.2011.12.002_bb0015","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1016\/j.joca.2005.02.009","article-title":"Systematic review of therapies for osteoarthritis of the hand","volume":"13","author":"Towheed","year":"2005","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.jmpt.2011.12.002_bb0020","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/S0004-9514(05)70005-2","article-title":"No difference between two splint and exercise regimens for people with osteoarthritis of the thumb: a randomised controlled trial","volume":"51","author":"Wajon","year":"2005","journal-title":"Aust J Physiother"},{"key":"10.1016\/j.jmpt.2011.12.002_bb0025","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1136\/pgmj.2006.046300","article-title":"Basal thumb arthritis","volume":"83","author":"Dias","year":"2007","journal-title":"Postgrad Med J"},{"key":"10.1016\/j.jmpt.2011.12.002_bb0030","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.cuor.2007.02.006","article-title":"Osteoarthritis of the thumb trapeziometacarpal joint","volume":"21","author":"Batra","year":"2007","journal-title":"Current Orthopaedics"},{"key":"10.1016\/j.jmpt.2011.12.002_bb0035","doi-asserted-by":"crossref","first-page":"386","DOI":"10.2519\/jospt.2003.33.7.386","article-title":"The carpometacarpal joint of the thumb: stability, deformity, and therapeutic intervention","volume":"33","author":"Neumann","year":"2003","journal-title":"J Orthop Sports Phys Ther"},{"key":"10.1016\/j.jmpt.2011.12.002_bb0040","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1007\/s10067-003-0792-4","article-title":"The effect of hand osteoarthritis on grip and pinch strength and hand function in postmenopausal women","volume":"22","author":"Bagis","year":"2003","journal-title":"Clin Rheumatol"},{"key":"10.1016\/j.jmpt.2011.12.002_bb0045","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/S0266-7681(96)80094-5","article-title":"First carpometacarpal joint arthritis. A comparison of two arthroplasty techniques","volume":"21","author":"Livesey","year":"1996","journal-title":"J Hand Surg Br"},{"key":"10.1016\/j.jmpt.2011.12.002_bb0050","doi-asserted-by":"crossref","first-page":"70","DOI":"10.5014\/ajot.61.1.70","article-title":"Splinting for osteoarthritis of the carpometacarpal joint: a review of the evidence","volume":"61","author":"Egan","year":"2007","journal-title":"Am J Occup Ther"},{"key":"10.1016\/j.jmpt.2011.12.002_bb0055","doi-asserted-by":"crossref","first-page":"661","DOI":"10.7326\/0003-4819-150-10-200905190-00003","article-title":"Splint for base-of-thumb osteoarthritis: a randomized trial","volume":"150","author":"Rannou","year":"2009","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.jmpt.2011.12.002_bb0060","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1016\/j.math.2009.01.005","article-title":"The convex-concave rule and the lever law","volume":"14","author":"Schomacher","year":"2009","journal-title":"Man Ther"},{"key":"10.1016\/j.jmpt.2011.12.002_bb0065","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1016\/j.math.2008.06.003","article-title":"Biomechanical analysis of axial distraction mobilization of the glenohumeral joint\u2014a cadaver study","volume":"14","author":"Hsu","year":"2009","journal-title":"Man Ther"},{"key":"10.1016\/j.jmpt.2011.12.002_bb0070","first-page":"26","article-title":"Manual mobilization of the extremity joints. Basic examination and treatment techniques (i)","author":"Kaltenborn","year":"1989"},{"key":"10.1016\/j.jmpt.2011.12.002_bb0075","series-title":"Vertebral manipulation","first-page":"3","author":"Maitland","year":"1998"},{"key":"10.1016\/j.jmpt.2011.12.002_bb0080","series-title":"Manual Therapy: \u201cNAGS\u201d, \u201cSNAGS\u201d, \u201cMWMS\u201d, etc","author":"Mulligan","year":"1999"},{"key":"10.1016\/j.jmpt.2011.12.002_bb0085","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1016\/j.jmpt.2011.05.016","article-title":"Short-term effects of the neurodynamic mobilization in patients with secondary thumb carpometacarpal osteoarthritis","volume":"34","author":"Villafa\u00f1e","year":"2011","journal-title":"J Manipulative Physiol Ther"},{"key":"10.1016\/j.jmpt.2011.12.002_bb0090","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1016\/j.jmpt.2011.08.005","article-title":"Hypoalgesic and motor effects of Kaltenborn mobilization on elderly patients with secondary thumb carpometacarpal osteoarthritis. A randomized, controlled trial","volume":"34","author":"Villafa\u00f1e","year":"2011","journal-title":"J Manipulative Physiol Ther"},{"key":"10.1016\/j.jmpt.2011.12.002_bb0095","doi-asserted-by":"crossref","DOI":"10.1016\/j.apmr.2011.08.045","article-title":"Radial nerve mobilization decreases pain sensitivity and improves motor performance in patients with thumb carpometacarpal osteoarthritis: a randomized, controlled trial","author":"Villafa\u00f1e","year":"2012","journal-title":"Arch Phys Med Rehabil"},{"key":"10.1016\/j.jmpt.2011.12.002_bb0100","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.math.2010.10.011","article-title":"Manual therapy for osteoarthritis of the hip or knee\u2014a systematic review","volume":"16","author":"French","year":"2011","journal-title":"Man Ther"},{"key":"10.1016\/j.jmpt.2011.12.002_bb0105","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1053\/eujp.2000.0223","article-title":"Knee joint mobilization reduces secondary mechanical hyperalgesia induced by capsaicin injection into the ankle joint","volume":"5","author":"Sluka","year":"2001","journal-title":"Eur J Pain"},{"key":"10.1016\/j.jmpt.2011.12.002_bb0110","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1054\/math.2000.0378","article-title":"Cervical mobilisation: concurrent effects on pain, sympathetic nervous system activity and motor activity","volume":"6","author":"Sterling","year":"2001","journal-title":"Man Ther"},{"key":"10.1016\/j.jmpt.2011.12.002_bb0115","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/S0304-3959(96)03221-6","article-title":"The initial effects of a cervical spine manipulative physiotherapy treatment on the pain and dysfunction of lateral epicondylalgia","volume":"68","author":"Vicenzino","year":"1996","journal-title":"Pain"},{"key":"10.1016\/j.jmpt.2011.12.002_bb0120","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1016\/j.jmpt.2008.10.005","article-title":"Immediate hypoalgesic and motor effects after a single cervical spine manipulation in subjects with lateral epicondylalgia","volume":"31","author":"Fernandez-Carnero","year":"2008","journal-title":"J Manipulative Physiol Ther"},{"key":"10.1016\/j.jmpt.2011.12.002_bb0125","first-page":"1309","article-title":"Practice tips. Rule of thumb: update on first carpometacarpal joint osteoarthritis","volume":"53","author":"Jaggi","year":"2007","journal-title":"Can Fam Physician"},{"key":"10.1016\/j.jmpt.2011.12.002_bb0130","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1093\/ptj\/78.2.160","article-title":"Reliability of clinical pressure-pain algometric measurements obtained on consecutive days","volume":"78","author":"Nussbaum","year":"1998","journal-title":"Phys Ther"},{"key":"10.1016\/j.jmpt.2011.12.002_bb0135","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/S0004-9514(07)70032-6","article-title":"Pressure algometry","volume":"53","author":"Ylinen","year":"2007","journal-title":"Aust J Physiother"},{"issue":"Pt 6","key":"10.1016\/j.jmpt.2011.12.002_bb0140","doi-asserted-by":"crossref","first-page":"1472","DOI":"10.1093\/brain\/awp050","article-title":"Bilateral widespread mechanical pain sensitivity in carpal tunnel syndrome: evidence of central processing in unilateral neuropathy","volume":"132","author":"Fernandez-de-las-Penas","year":"2009","journal-title":"Brain"},{"key":"10.1016\/j.jmpt.2011.12.002_bb0145","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1016\/j.jmpt.2008.04.006","article-title":"Changes in pressure pain thresholds over C5-C6 zygapophyseal joint after a cervicothoracic junction manipulation in healthy subjects","volume":"31","author":"Fernandez-de-Las-Penas","year":"2008","journal-title":"J Manipulative Physiol Ther"},{"key":"10.1016\/j.jmpt.2011.12.002_bb0150","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1097\/AJP.0b013e318154b6ae","article-title":"Interrater reliability of algometry in measuring pressure pain thresholds in healthy humans, using multiple raters","volume":"23","author":"Chesterton","year":"2007","journal-title":"Clin J Pain"},{"key":"10.1016\/j.jmpt.2011.12.002_bb0155","first-page":"145","article-title":"Application of pressure algometry in manual medicine","volume":"5","author":"Fischer","year":"1990","journal-title":"J Man Med"},{"key":"10.1016\/j.jmpt.2011.12.002_bb0160","doi-asserted-by":"crossref","first-page":"325","DOI":"10.2519\/jospt.2007.2542","article-title":"Immediate effects on pressure pain threshold following a single cervical spine manipulation in healthy subjects","volume":"37","author":"Fernandez-de-las-Penas","year":"2007","journal-title":"J Orthop Sports Phys Ther"},{"key":"10.1016\/j.jmpt.2011.12.002_bb0165","first-page":"69","article-title":"Grip and pinch strength: normative data for adults","volume":"66","author":"Mathiowetz","year":"1985","journal-title":"Arch Phys Med Rehabil"},{"key":"10.1016\/j.jmpt.2011.12.002_bb0170","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1093\/rheumatology\/38.6.521","article-title":"Predicting \u201cnormal\u201d grip strength for rheumatoid arthritis patients","volume":"38","author":"Fraser","year":"1999","journal-title":"Rheumatology (Oxford)"},{"key":"10.1016\/j.jmpt.2011.12.002_bb0175","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1177\/230949900601400113","article-title":"Basal thumb metacarpal osteotomy for trapeziometacarpal osteoarthritis","volume":"14","author":"Gwynne-Jones","year":"2006","journal-title":"J Orthop Surg (Hong Kong)"},{"key":"10.1016\/j.jmpt.2011.12.002_bb0180","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1093\/ptj\/83.9.806","article-title":"Measurement error in grip and pinch force measurements in patients with hand injuries","volume":"83","author":"Schreuders","year":"2003","journal-title":"Phys Ther"},{"key":"10.1016\/j.jmpt.2011.12.002_bb0185","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.math.2009.09.004","article-title":"Cervical lateral glide increases nociceptive flexion reflex threshold but not pressure or thermal pain thresholds in chronic whiplash associated disorders: a pilot randomised controlled trial","volume":"15","author":"Sterling","year":"2010","journal-title":"Man Ther."},{"key":"10.1016\/j.jmpt.2011.12.002_bb0190","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1093\/ageing\/afl024","article-title":"Is grip strength associated with health-related quality of life? Findings from the Hertfordshire Cohort Study","volume":"35","author":"Sayer","year":"2006","journal-title":"Age Ageing"},{"key":"10.1016\/j.jmpt.2011.12.002_bb0195","first-page":"84","article-title":"Effect of early mobilisation on grip strength, pinch strength and work of hand muscles in cases of closed diaphyseal fracture radius-ulna treated with dynamic compression plating","volume":"46","author":"Solanki","year":"2000","journal-title":"J Postgrad Med"},{"key":"10.1016\/j.jmpt.2011.12.002_bb0200","doi-asserted-by":"crossref","first-page":"2978","DOI":"10.1210\/jc.2007-2600","article-title":"Muscle function improves during growth hormone therapy in short children born small for gestational age: results of a peripheral quantitative computed tomography study on body composition","volume":"93","author":"Schweizer","year":"2008","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.jmpt.2011.12.002_bb0205","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1002\/art.22623","article-title":"The Australian\/Canadian osteoarthritis hand index in a community-dwelling population of older adults: reliability and validity","volume":"57","author":"Dziedzic","year":"2007","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.jmpt.2011.12.002_bb0210","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1002\/art.21615","article-title":"Validity, factor structure, and clinical relevance of the AUSCAN Osteoarthritis Hand Index","volume":"54","author":"Allen","year":"2006","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.jmpt.2011.12.002_bb0215","doi-asserted-by":"crossref","first-page":"984","DOI":"10.1093\/ptj\/81.4.984","article-title":"A randomized controlled trial of a passive accessory joint mobilization on acute ankle inversion sprains","volume":"81","author":"Green","year":"2001","journal-title":"Phys Ther"},{"key":"10.1016\/j.jmpt.2011.12.002_bb0220","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1054\/math.1996.0259","article-title":"Peripheral mobilisations with movement","volume":"1","author":"Exelby","year":"1996","journal-title":"Man Ther"},{"key":"10.1016\/j.jmpt.2011.12.002_bb0225","doi-asserted-by":"crossref","first-page":"243","DOI":"10.3944\/AOTT.2009.243","article-title":"The value of intermittent ultrasound treatment in subacromial impingement syndrome","volume":"43","author":"Celik","year":"2009","journal-title":"Acta Orthop Traumatol Turc"},{"key":"10.1016\/j.jmpt.2011.12.002_bb0230","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1007\/s00586-008-0679-9","article-title":"Independent evaluation of a clinical prediction rule for spinal manipulative therapy: a randomised controlled trial","volume":"17","author":"Hancock","year":"2008","journal-title":"Eur Spine J"},{"key":"10.1016\/j.jmpt.2011.12.002_bb0235","doi-asserted-by":"crossref","first-page":"c2756","DOI":"10.1136\/bmj.c2756","article-title":"Efficacy of standardised manual therapy and home exercise programme for chronic rotator cuff disease: randomised placebo controlled trial","volume":"340","author":"Bennell","year":"2010","journal-title":"BMJ"},{"key":"10.1016\/j.jmpt.2011.12.002_bb0240","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jmpt.2008.12.002","article-title":"Submitting manuscripts to biomedical journals: common errors and helpful solutions","volume":"32","author":"Johnson","year":"2009","journal-title":"J Manipulative Physiol Ther"},{"key":"10.1016\/j.jmpt.2011.12.002_bb0245","first-page":"448","article-title":"An investigation of the interrelationship between manipulative therapy-induced hypoalgesia and sympathoexcitation","volume":"21","author":"Vicenzino","year":"1998","journal-title":"J Manipulative Physiol Ther"},{"key":"10.1016\/j.jmpt.2011.12.002_bb0250","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1093\/ptj\/83.4.374","article-title":"Hypoalgesic and sympathoexcitatory effects of mobilization with movement for lateral epicondylalgia","volume":"83","author":"Paungmali","year":"2003","journal-title":"Phys Ther"},{"key":"10.1016\/j.jmpt.2011.12.002_bb0255","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1067\/mem.2001.118012","article-title":"Clinically significant changes in pain along the visual analog scale","volume":"38","author":"Bird","year":"2001","journal-title":"Ann Emerg Med"},{"key":"10.1016\/j.jmpt.2011.12.002_bb0260","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.math.2006.02.009","article-title":"The initial effects of knee joint mobilization on osteoarthritic hyperalgesia","volume":"12","author":"Moss","year":"2007","journal-title":"Man Ther"},{"key":"10.1016\/j.jmpt.2011.12.002_bb0265","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1067\/mem.2001.118863","article-title":"Prospective validation of clinically important changes in pain severity measured on a visual analog scale","volume":"38","author":"Gallagher","year":"2001","journal-title":"Ann Emerg Med"},{"key":"10.1016\/j.jmpt.2011.12.002_bb0270","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/j.math.2011.01.001","article-title":"Hypoalgesic effect of a passive accessory mobilisation technique in patients with lateral ankle pain","volume":"16","author":"Yeo","year":"2011","journal-title":"Man Ther"},{"key":"10.1016\/j.jmpt.2011.12.002_bb0275","doi-asserted-by":"crossref","first-page":"709","DOI":"10.2519\/jospt.2009.3117","article-title":"A randomized sham-controlled trial of a neurodynamic technique in the treatment of carpal tunnel syndrome","volume":"39","author":"Bialosky","year":"2009","journal-title":"J Orthop Sports Phys Ther"},{"key":"10.1016\/j.jmpt.2011.12.002_bb0280","doi-asserted-by":"crossref","first-page":"428","DOI":"10.2519\/jospt.2009.2954","article-title":"Effects of upper extremity neural mobilization on thermal pain sensitivity: a sham-controlled study in asymptomatic participants","volume":"39","author":"Beneciuk","year":"2009","journal-title":"J Orthop Sports Phys Ther"},{"key":"10.1016\/j.jmpt.2011.12.002_bb0285","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1016\/j.psyneuen.2005.04.007","article-title":"Long-term potentiation in spinal nociceptive systems\u2014how acute pain may become chronic","volume":"30","author":"Rygh","year":"2005","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.jmpt.2011.12.002_bb0290","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/j.jmpt.2009.12.001","article-title":"Neurodynamic mobilization in the conservative treatment of cubital tunnel syndrome: long-term follow-up of 7 cases","volume":"33","author":"Oskay","year":"2010","journal-title":"J Manipulative Physiol Ther"},{"key":"10.1016\/j.jmpt.2011.12.002_bb0295","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/j.jbmt.2006.11.004","article-title":"Indirect influence of specific Kaltenborn glide mobilizations of the carpal joint on a subject with neurological impairments","volume":"11","author":"Herrero-Gallego","year":"2007","journal-title":"J Bodyw Mov Ther"},{"key":"10.1016\/j.jmpt.2011.12.002_bb0300","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.pain.2010.03.025","article-title":"Heterogeneous sensory processing in persistent postherniotomy pain","volume":"150","author":"Aasvang","year":"2010","journal-title":"Pain"},{"key":"10.1016\/j.jmpt.2011.12.002_bb0305","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1097\/AJP.0b013e3181643403","article-title":"Validity of cross-friction algometry procedure in referred muscle pain syndromes: preliminary results of a new referred pain provocation technique with the aid of a Fischer pressure algometer in patients with nonspecific low back pain","volume":"24","author":"Farasyn","year":"2008","journal-title":"Clin J Pain"}],"container-title":["Journal of Manipulative and Physiological Therapeutics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0161475411002600?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0161475411002600?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T08:54:45Z","timestamp":1784796885000},"score":1,"resource":{"primary":{"URL":"https:\/\/jmpt.kglmeridian.com\/doi\/10.1016\/j.jmpt.2011.12.002"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,2]]},"references-count":61,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2012,2]]}},"alternative-id":["S0161475411002600"],"URL":"https:\/\/doi.org\/10.1016\/j.jmpt.2011.12.002","relation":{},"ISSN":["0161-4754"],"issn-type":[{"value":"0161-4754","type":"print"}],"subject":[],"published":{"date-parts":[[2012,2]]}}}