{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T19:24:27Z","timestamp":1788809067616,"version":"build-2803163510"},"reference-count":37,"publisher":"National University of Health Sciences","issue":"1","license":[{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100009850","name":"UQTR","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009850","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jmptonline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Manipulative and Physiological Therapeutics"],"published-print":{"date-parts":[[2022,1]]},"DOI":"10.1016\/j.jmpt.2022.03.016","type":"journal-article","created":{"date-parts":[[2022,6,24]],"date-time":"2022-06-24T01:06:50Z","timestamp":1656032810000},"page":"1-8","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"title":["Neuromechanical Responses to Spinal Manipulation and Mobilization: A Crossover Randomized Clinical Trial"],"prefix":"10.67400","volume":"45","author":[{"given":"Arnaud","family":"Lardon","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabelle","family":"Pag\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fran\u00e7ois","family":"Nougarou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Descarreaux","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"57152","reference":[{"key":"10.1016\/j.jmpt.2022.03.016_bib0001","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1186\/1471-2474-10-39","article-title":"Pain in the lumbar, thoracic or cervical regions: do age and gender matter? A population-based study of 34,902 Danish twins 20-71 years of age","volume":"10","author":"Leboeuf-Yde","year":"2009","journal-title":"BMC Musculoskelet Disord"},{"key":"10.1016\/j.jmpt.2022.03.016_bib0002","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1186\/1471-2474-12-39","article-title":"Consequences of spinal pain: do age and gender matter? A Danish cross-sectional population-based study of 34,902 individuals 20-71 years of age","volume":"12","author":"Leboeuf-Yde","year":"2011","journal-title":"BMC Musculoskelet Disord"},{"key":"10.1016\/j.jmpt.2022.03.016_bib0003","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1186\/1471-2474-12-98","article-title":"Prevalence and tracking of back pain from childhood to adolescence","volume":"12","author":"Kjaer","year":"2011","journal-title":"BMC Musculoskelet Disord"},{"issue":"1","key":"10.1016\/j.jmpt.2022.03.016_bib0004","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1002\/ejp.884","article-title":"Incidence and prognosis of mid-back pain in the general population: a systematic review","volume":"21","author":"Johansson","year":"2017","journal-title":"Eur J Pain"},{"issue":"7","key":"10.1016\/j.jmpt.2022.03.016_bib0005","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1016\/j.jmpt.2015.06.001","article-title":"The effectiveness of noninvasive interventions for musculoskeletal thoracic spine and chest wall pain: a systematic review by the Ontario Protocol for Traffic Injury Management (OPTIMa) collaboration","volume":"38","author":"Southerst","year":"2015","journal-title":"J Manipulative Physiol Ther"},{"issue":"2","key":"10.1016\/j.jmpt.2022.03.016_bib0006","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1002\/ejp.931","article-title":"Clinical practice guidelines for the noninvasive management of low back pain: a systematic review by the Ontario Protocol for Traffic Injury Management (OPTIMa) Collaboration","volume":"21","author":"Wong","year":"2017","journal-title":"Eur J Pain"},{"issue":"12","key":"10.1016\/j.jmpt.2022.03.016_bib0007","doi-asserted-by":"crossref","first-page":"1541","DOI":"10.1016\/j.spinee.2014.06.019","article-title":"Is multimodal care effective for the management of patients with whiplash-associated disorders or neck pain and associated disorders? A systematic review by the Ontario Protocol for Traffic Injury Management (OPTIMa) Collaboration","volume":"16","author":"Sutton","year":"2016","journal-title":"Spine J"},{"issue":"3","key":"10.1016\/j.jmpt.2022.03.016_bib0008","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/j.spinee.2003.06.002","article-title":"Efficacy of spinal manipulation and mobilization for low back pain and neck pain: a systematic review and best evidence synthesis","volume":"4","author":"Bronfort","year":"2004","journal-title":"Spine J"},{"issue":"11","key":"10.1016\/j.jmpt.2022.03.016_bib0009","doi-asserted-by":"crossref","first-page":"871","DOI":"10.7326\/0003-4819-138-11-200306030-00008","article-title":"Spinal manipulative therapy for low back pain. A meta-analysis of effectiveness relative to other therapies","volume":"138","author":"Assendelft","year":"2003","journal-title":"Ann Intern Med"},{"issue":"4","key":"10.1016\/j.jmpt.2022.03.016_bib0010","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1016\/j.jmpt.2006.03.006","article-title":"Manual forces applied during posterior-to-anterior spinal mobilization: a review of the evidence","volume":"29","author":"Snodgrass","year":"2006","journal-title":"J Manipulative Physiol Ther"},{"issue":"1","key":"10.1016\/j.jmpt.2022.03.016_bib0011","first-page":"53","article-title":"The use and misuse of the terms manipulation and mobilization in the literature establishing their efficacy in the treatment of lumbar spine disorders","volume":"54","author":"Kotoulas","year":"2002","journal-title":"Physiother Can"},{"issue":"25","key":"10.1016\/j.jmpt.2022.03.016_bib0012","doi-asserted-by":"crossref","first-page":"2720","DOI":"10.1097\/BRS.0b013e3181b48809","article-title":"Comparison of the effectiveness of three manual physical therapy techniques in a subgroup of patients with low back pain who satisfy a clinical prediction rule: a randomized clinical trial","volume":"34","author":"Cleland","year":"2009","journal-title":"Spine (Phila Pa 1976)"},{"issue":"9","key":"10.1016\/j.jmpt.2022.03.016_bib0013","doi-asserted-by":"crossref","first-page":"1206","DOI":"10.1097\/00007632-199307000-00014","volume":"18","author":"Herzog","year":"1993","journal-title":"Forces exerted during spinal manipulative therapy. Spine (Phila Pa 1976)"},{"key":"10.1016\/j.jmpt.2022.03.016_bib0014","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1186\/s12906-016-1153-6","article-title":"Neuromechanical response to spinal manipulation therapy: effects of a constant rate of force application","volume":"16","author":"Nougarou","year":"2016","journal-title":"BMC Complement Altern Med"},{"issue":"9","key":"10.1016\/j.jmpt.2022.03.016_bib0015","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1016\/j.jmpt.2013.08.006","article-title":"Physiological responses to spinal manipulation therapy: investigation of the relationship between electromyographic responses and peak force","volume":"36","author":"Nougarou","year":"2013","journal-title":"J Manipulative Physiol Ther"},{"issue":"2","key":"10.1016\/j.jmpt.2022.03.016_bib0016","first-page":"141","article-title":"The effect of spinal manipulation impulse duration on spine neuromechanical responses","volume":"58","author":"Page","year":"2014","journal-title":"J Can Chiropr Assoc"},{"issue":"12","key":"10.1016\/j.jmpt.2022.03.016_bib0017","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0208790","article-title":"Changes in spinal stiffness with chronic thoracic pain: correlation with pain and muscle activity","volume":"13","author":"Page","year":"2018","journal-title":"PLoS One"},{"issue":"2","key":"10.1016\/j.jmpt.2022.03.016_bib0018","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/0895-4356(96)00526-4","article-title":"The Quebec Back Pain Disability Scale: conceptualization and development","volume":"49","author":"Kopec","year":"1996","journal-title":"J Clin Epidemiol"},{"key":"10.1016\/j.jmpt.2022.03.016_bib0019","doi-asserted-by":"crossref","DOI":"10.1155\/2011\/494196","article-title":"Pain-related fear: a critical review of the related measures","author":"Lundberg","year":"2011","journal-title":"Pain Res Treat. 2011"},{"issue":"2","key":"10.1016\/j.jmpt.2022.03.016_bib0020","doi-asserted-by":"crossref","first-page":"E123","DOI":"10.1097\/BRS.0000000000000062","article-title":"Validity and reliability of the French version of the STarT Back screening tool for patients with low back pain","volume":"39","author":"Bruyere","year":"2014","journal-title":"Spine (Phila Pa 1976)"},{"issue":"5","key":"10.1016\/j.jmpt.2022.03.016_bib0021","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1016\/j.jelekin.2012.04.015","article-title":"A structured review of spinal stiffness as a kinesiological outcome of manipulation: its measurement and utility in diagnosis, prognosis and treatment decision-making","volume":"22","author":"Snodgrass","year":"2012","journal-title":"J Electromyogr Kinesiol"},{"issue":"2","key":"10.1016\/j.jmpt.2022.03.016_bib0022","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.jmpt.2012.12.007","article-title":"Standardization of spinal manipulation therapy in humans: development of a novel device designed to measure dose-response","volume":"36","author":"Descarreaux","year":"2013","journal-title":"J Manipulative Physiol Ther"},{"key":"10.1016\/j.jmpt.2022.03.016_bib0023","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/j.math.2016.09.005","article-title":"Development of a new palpation method using alternative landmarks for the determination of thoracic transverse processes: An in vitro study","volume":"27","author":"Page","year":"2017","journal-title":"Musculoskelet Sci Pract"},{"key":"10.1016\/j.jmpt.2022.03.016_bib0024","first-page":"165","article-title":"Variation in vertebral levels of the vertebra prominens and sacral dimples in subjects with scoliosis","volume":"159","author":"Stonelake","year":"1988","journal-title":"J Anat"},{"issue":"2","key":"10.1016\/j.jmpt.2022.03.016_bib0025","first-page":"121","article-title":"The location of the inferior angle of the scapula in relation to the spinal level of prone patients","volume":"53","author":"Cooperstein","year":"2009","journal-title":"J Can Chiropr Assoc"},{"key":"10.1016\/j.jmpt.2022.03.016_bib0026","unstructured":"Randomization.com. Available at: http:\/\/www.randomization.com\/. Accessed February 2016."},{"issue":"8","key":"10.1016\/j.jmpt.2022.03.016_bib0027","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1067\/mmt.2001.118208","article-title":"Responsiveness of visual analogue and McGill Pain Scale measures","volume":"24","author":"Scrimshaw","year":"2001","journal-title":"J Manipulative Physiol Ther"},{"issue":"21","key":"10.1016\/j.jmpt.2022.03.016_bib0028","doi-asserted-by":"crossref","first-page":"1772","DOI":"10.1097\/BRS.0b013e318216337d","article-title":"Preliminary investigation of the mechanisms underlying the effects of manipulation: exploration of a multivariate model including spinal stiffness, multifidus recruitment, and clinical findings","volume":"36","author":"Fritz","year":"2011","journal-title":"Spine (Phila Pa 1976)"},{"issue":"17","key":"10.1016\/j.jmpt.2022.03.016_bib0029","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1097\/BRS.0000000000000981","article-title":"Do participants with low back pain who respond to spinal manipulative therapy differ biomechanically from nonresponders, untreated controls or asymptomatic controls?","volume":"40","author":"Wong","year":"2015","journal-title":"Spine (Phila Pa 1976)"},{"issue":"6","key":"10.1016\/j.jmpt.2022.03.016_bib0030","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/0268-0033(93)90004-2","article-title":"Manipulation: investigation of a proposed mechanism","volume":"8","author":"Lee","year":"1993","journal-title":"Clin Biomech (Bristol, Avon)"},{"issue":"11","key":"10.1016\/j.jmpt.2022.03.016_bib0031","doi-asserted-by":"crossref","first-page":"685","DOI":"10.2519\/jospt.2010.3271","article-title":"The effects of thoracic manipulation on posteroanterior spinal stiffness","volume":"40","author":"Campbell","year":"2010","journal-title":"J Orthop Sports Phys Ther"},{"issue":"2","key":"10.1016\/j.jmpt.2022.03.016_bib0032","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1097\/BRS.0000000000001151","article-title":"Mechanism of action of spinal mobilizations: a systematic review","volume":"41","author":"Lascurain-Aguirrebena","year":"2016","journal-title":"Spine (Phila Pa 1976)"},{"issue":"1","key":"10.1016\/j.jmpt.2022.03.016_bib0033","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1186\/2045-709X-20-26","article-title":"The effect of spinal manipulative therapy on experimentally induced pain: a systematic literature review","volume":"20","author":"Millan","year":"2012","journal-title":"Chiropr Man Therap"},{"issue":"5","key":"10.1016\/j.jmpt.2022.03.016_bib0034","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1016\/j.jmpt.2009.04.002","article-title":"Is it reasonable to use an individual patient's progress after treatment as a guide to ongoing clinical reasoning?","volume":"32","author":"Tuttle","year":"2009","journal-title":"J Manipulative Physiol Ther"},{"issue":"8","key":"10.1016\/j.jmpt.2022.03.016_bib0035","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1016\/j.pmrj.2016.12.001","article-title":"The clinical value of assessing lumbar posteroanterior segmental stiffness: a narrative review of manual and instrumented methods","volume":"9","author":"Wong","year":"2017","journal-title":"PM R"},{"issue":"5","key":"10.1016\/j.jmpt.2022.03.016_bib0036","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1016\/j.math.2008.09.001","article-title":"The mechanisms of manual therapy in the treatment of musculoskeletal pain: a comprehensive model","volume":"14","author":"Bialosky","year":"2009","journal-title":"Man Ther"},{"issue":"6","key":"10.1016\/j.jmpt.2022.03.016_bib0037","doi-asserted-by":"crossref","first-page":"389","DOI":"10.2519\/jospt.2011.3632","article-title":"Association between changes in abdominal and lumbar multifidus muscle thickness and clinical improvement after spinal manipulation","volume":"41","author":"Koppenhaver","year":"2011","journal-title":"J Orthop Sports Phys Ther"}],"container-title":["Journal of Manipulative and Physiological Therapeutics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S016147542200032X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S016147542200032X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T08:58:08Z","timestamp":1784797088000},"score":1,"resource":{"primary":{"URL":"https:\/\/jmpt.kglmeridian.com\/doi\/10.1016\/j.jmpt.2022.03.016"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1]]},"references-count":37,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,1]]}},"alternative-id":["S016147542200032X"],"URL":"https:\/\/doi.org\/10.1016\/j.jmpt.2022.03.016","relation":{},"ISSN":["0161-4754"],"issn-type":[{"value":"0161-4754","type":"print"}],"subject":[],"published":{"date-parts":[[2022,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Neuromechanical Responses to Spinal Manipulation and Mobilization: A Crossover Randomized Clinical Trial","name":"articletitle","label":"Article Title"},{"value":"Journal of Manipulative and Physiological Therapeutics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jmpt.2022.03.016","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 by National University of Health Sciences.","name":"copyright","label":"Copyright"}]}}