{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T18:28:18Z","timestamp":1773944898959,"version":"3.50.1"},"reference-count":21,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2009,4,1]],"date-time":"2009-04-01T00:00:00Z","timestamp":1238544000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Magnetic Resonance"],"published-print":{"date-parts":[[2009,4]]},"DOI":"10.1016\/j.jmr.2008.12.018","type":"journal-article","created":{"date-parts":[[2008,12,25]],"date-time":"2008-12-25T10:32:05Z","timestamp":1230201125000},"page":"181-185","source":"Crossref","is-referenced-by-count":47,"title":["Pulsed EPR imaging of nitroxides in mice"],"prefix":"10.1016","volume":"197","author":[{"given":"Fuminori","family":"Hyodo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shingo","family":"Matsumoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nallathamby","family":"Devasahayam","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher","family":"Dharmaraj","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sankaran","family":"Subramanian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James B.","family":"Mitchell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Murali C.","family":"Krishna","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jmr.2008.12.018_bib1","doi-asserted-by":"crossref","first-page":"2802","DOI":"10.1021\/bi00463a024","article-title":"Biologically active metal-independent superoxide dismutase mimics","volume":"29","author":"Mitchell","year":"1990","journal-title":"Biochemistry"},{"key":"10.1016\/j.jmr.2008.12.018_bib2","doi-asserted-by":"crossref","first-page":"1632","DOI":"10.1016\/j.freeradbiomed.2007.02.030","article-title":"The chemistry and biology of nitroxide compounds","volume":"42","author":"Soule","year":"2007","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.jmr.2008.12.018_bib3","doi-asserted-by":"crossref","first-page":"6411","DOI":"10.1158\/1078-0432.CCR-04-0658","article-title":"A phase I study of topical Tempol for the prevention of alopecia induced by whole brain radiotherapy","volume":"10","author":"Metz","year":"2004","journal-title":"Clin. Cancer Res."},{"key":"10.1016\/j.jmr.2008.12.018_bib4","first-page":"307","article-title":"Noninvasive imaging of tumor redox status and its modification by tissue glutathione levels","volume":"62","author":"Kuppusamy","year":"2002","journal-title":"Cancer Res."},{"key":"10.1016\/j.jmr.2008.12.018_bib5","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.jmr.2008.04.035","article-title":"Development and testing of a CW-EPR apparatus for imaging of short-lifetime nitroxyl radicals in mouse head","volume":"193","author":"Sato-Akaba","year":"2008","journal-title":"J. Magn. Reson."},{"key":"10.1016\/j.jmr.2008.12.018_bib6","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/cmr.b.20028","article-title":"A composite resonator assembly suitable for EPR\/NMR coregistration imaging","volume":"25B","author":"Matsumoto","year":"2005","journal-title":"Conc. Magn. Reson. B Magn. Reson. Eng."},{"key":"10.1016\/j.jmr.2008.12.018_bib7","doi-asserted-by":"crossref","first-page":"9921","DOI":"10.1158\/0008-5472.CAN-06-0879","article-title":"Probing the intracellular redox status of tumors with magnetic resonance imaging and redox-sensitive contrast agents","volume":"66","author":"Hyodo","year":"2006","journal-title":"Cancer Res."},{"key":"10.1016\/j.jmr.2008.12.018_bib8","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.jmr.2007.10.013","article-title":"Monitoring redox-sensitive paramagnetic contrast agent by EPRI, OMRI and MRI","volume":"190","author":"Hyodo","year":"2008","journal-title":"J. Magn. Reson."},{"key":"10.1016\/j.jmr.2008.12.018_bib9","doi-asserted-by":"crossref","first-page":"2455","DOI":"10.1158\/1078-0432.CCR-05-2747","article-title":"High-resolution mapping of tumor redox status by magnetic resonance imaging using nitroxides as redox-sensitive contrast agents","volume":"12","author":"Matsumoto","year":"2006","journal-title":"Clin. Cancer Res."},{"key":"10.1016\/j.jmr.2008.12.018_bib10","first-page":"431","article-title":"Field-cycled proton\u2013electron double-resonance imaging of free radicals in large aqueous samples","volume":"84","author":"Lurie","year":"1989","journal-title":"J. Magn. Reson."},{"key":"10.1016\/j.jmr.2008.12.018_bib11","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1002\/mrm.21198","article-title":"Advantageous application of a surface coil to EPR irradiation in Overhauser-enhanced MRI","volume":"57","author":"Matsumoto","year":"2007","journal-title":"Magn. Reson. Med."},{"key":"10.1016\/j.jmr.2008.12.018_bib12","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1002\/mrm.1910030126","article-title":"Hypoxia-sensitive NMR contrast agents","volume":"3","author":"Swartz","year":"1986","journal-title":"Magn. Reson. Med."},{"key":"10.1016\/j.jmr.2008.12.018_bib13","doi-asserted-by":"crossref","first-page":"1463","DOI":"10.1073\/pnas.0510670103","article-title":"Simultaneous molecular imaging of redox reactions monitored by Overhauser-enhanced MRI with 14N- and 15N-labeled nitroxyl radicals","volume":"103","author":"Utsumi","year":"2006","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.jmr.2008.12.018_bib14","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1038\/jcbfm.2008.5","article-title":"Brain redox imaging using blood\u2013brain barrier-permeable nitroxide MRI contrast agent","volume":"28","author":"Hyodo","year":"2008","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"10.1016\/j.jmr.2008.12.018_bib15","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1002\/nbm.897","article-title":"Radio frequency continuous-wave and time-domain EPR imaging and Overhauser-enhanced magnetic resonance imaging of small animals: instrumental developments and comparison of relative merits for functional imaging","volume":"17","author":"Subramanian","year":"2004","journal-title":"NMR Biomed."},{"key":"10.1016\/j.jmr.2008.12.018_bib16","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1002\/mrm.21500","article-title":"Dynamic monitoring of localized tumor oxygenation changes using RF pulsed electron paramagnetic resonance in conscious mice","volume":"59","author":"Matsumoto","year":"2008","journal-title":"Magn. Reson. Med."},{"key":"10.1016\/j.jmr.2008.12.018_bib17","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1002\/mrm.10199","article-title":"Single-point (constant-time) imaging in radiofrequency Fourier transform electron paramagnetic resonance","volume":"48","author":"Subramanian","year":"2002","journal-title":"Magn. Reson. Med."},{"key":"10.1016\/j.jmr.2008.12.018_bib18","first-page":"1965","article-title":"Low-field paramagnetic resonance imaging of tumor oxygenation and glycolytic activity in mice","volume":"118","author":"Matsumoto","year":"2008","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.jmr.2008.12.018_bib19","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1002\/mrm.21194","article-title":"Strategies for improved temporal and spectral resolution in in vivo oximetric imaging using time-domain EPR","volume":"57","author":"Devasahayam","year":"2007","journal-title":"Magn. Reson. Med."},{"key":"10.1016\/j.jmr.2008.12.018_bib20","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1080\/1071576031000107344","article-title":"Confirmation of superoxide generation via xanthine oxidase in streptozotocin-induced diabetic mice","volume":"37","author":"Matsumoto","year":"2003","journal-title":"Free Radic. Res."},{"key":"10.1016\/j.jmr.2008.12.018_bib21","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1007\/BF03166224","article-title":"Electron spin T2 of a nitroxyl radical at 250MHz measured by rapid-scan EPR","volume":"30","author":"Tseitlin","year":"2006","journal-title":"Appl. Magn. Reson."}],"container-title":["Journal of Magnetic Resonance"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1090780708004242?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1090780708004242?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,12,23]],"date-time":"2018-12-23T10:51:43Z","timestamp":1545562303000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1090780708004242"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,4]]},"references-count":21,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2009,4]]}},"alternative-id":["S1090780708004242"],"URL":"https:\/\/doi.org\/10.1016\/j.jmr.2008.12.018","relation":{},"ISSN":["1090-7807"],"issn-type":[{"value":"1090-7807","type":"print"}],"subject":[],"published":{"date-parts":[[2009,4]]}}}