{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T07:57:02Z","timestamp":1790841422582,"version":"4.1.0"},"reference-count":40,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,8,8]],"date-time":"2026-08-08T00:00:00Z","timestamp":1786147200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100012389","name":"National Institute of Information and Communications Technology","doi-asserted-by":"publisher","award":["RS-2025-25464788"],"award-info":[{"award-number":["RS-2025-25464788"]}],"id":[{"id":"10.13039\/501100012389","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003626","name":"Defense Acquisition Program Administration","doi-asserted-by":"publisher","award":["KRIT-CT-23-031"],"award-info":[{"award-number":["KRIT-CT-23-031"]}],"id":[{"id":"10.13039\/501100003626","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100031839","name":"Korea Research Institute for Defense Technology Planning and Advancement","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100031839","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Magnetic Resonance"],"published-print":{"date-parts":[[2026,10]]},"DOI":"10.1016\/j.jmr.2026.108153","type":"journal-article","created":{"date-parts":[[2026,8,8]],"date-time":"2026-08-08T15:13:15Z","timestamp":1786201995000},"page":"108153","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Efficient iridium N-heterocyclic carbene catalysts for signal amplification by reversible exchange in dimethyl sulfoxide"],"prefix":"10.1016","volume":"391","author":[{"given":"Juhee","family":"Baek","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sein","family":"Min","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jisu","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min-Kun","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keunhong","family":"Jeong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.jmr.2026.108153_bb0005","doi-asserted-by":"crossref","first-page":"1417","DOI":"10.1021\/acs.chemrev.2c00534","article-title":"Spin hyperpolarization in modern magnetic resonance","volume":"123","author":"Eills","year":"2023","journal-title":"Chem. Rev."},{"issue":"8","key":"10.1016\/j.jmr.2026.108153_bb0010","first-page":"3156","article-title":"NMR hyperpolarization techniques for biomedicine","volume":"21","author":"Nikolaou","year":"2015","journal-title":"Chemistry (Weinheim an der Bergstrasse, Germany)"},{"key":"10.1016\/j.jmr.2026.108153_bb0015","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.pnmrs.2012.03.001","article-title":"The theory and practice of hyperpolarization in magnetic resonance using parahydrogen","volume":"67","author":"Green","year":"2012","journal-title":"Prog. Nucl. Magn. Reson. Spectrosc."},{"issue":"18","key":"10.1016\/j.jmr.2026.108153_bb0020","doi-asserted-by":"crossref","first-page":"5541","DOI":"10.1021\/ja00252a049","article-title":"Parahydrogen and synthesis allow dramatically enhanced nuclear alignment","volume":"109","author":"Bowers","year":"1987","journal-title":"J. Am. Chem. Soc."},{"issue":"5922","key":"10.1016\/j.jmr.2026.108153_bb0025","doi-asserted-by":"crossref","first-page":"1708","DOI":"10.1126\/science.1168877","article-title":"Reversible interactions with Para-hydrogen enhance NMR sensitivity by polarization transfer","volume":"323","author":"Adams","year":"2009","journal-title":"Science"},{"issue":"37","key":"10.1016\/j.jmr.2026.108153_bb0030","doi-asserted-by":"crossref","first-page":"13362","DOI":"10.1021\/ja903601p","article-title":"Spontaneous transfer of Para hydrogen derived spin order to pyridine at low magnetic field","volume":"131","author":"Atkinson","year":"2009","journal-title":"J. Am. Chem. Soc."},{"issue":"16","key":"10.1016\/j.jmr.2026.108153_bb0035","doi-asserted-by":"crossref","first-page":"6134","DOI":"10.1021\/ja200299u","article-title":"Iridium N-heterocyclic carbene complexes as efficient catalysts for magnetization transfer from Para-hydrogen","volume":"133","author":"Cowley","year":"2011","journal-title":"J. Am. Chem. Soc."},{"issue":"1","key":"10.1016\/j.jmr.2026.108153_bb0040","doi-asserted-by":"crossref","first-page":"4251","DOI":"10.1038\/s41467-018-06766-1","article-title":"Fine-tuning the efficiency of para-hydrogen-induced hyperpolarization by rational N-heterocyclic carbene design","volume":"9","author":"Rayner","year":"2018","journal-title":"Nat. Commun."},{"issue":"67","key":"10.1016\/j.jmr.2026.108153_bb0045","doi-asserted-by":"crossref","first-page":"7388","DOI":"10.1039\/c3cc43423k","article-title":"Ligand effects of NHC\u2013iridium catalysts for signal amplification by reversible exchange (SABRE)","volume":"49","author":"van Weerdenburg","year":"2013","journal-title":"Chem. Commun."},{"issue":"48","key":"10.1016\/j.jmr.2026.108153_bb0050","doi-asserted-by":"crossref","first-page":"13882","DOI":"10.1021\/jp510825b","article-title":"Irreversible catalyst activation enables hyperpolarization and water solubility for NMR signal amplification by reversible exchange","volume":"118","author":"Truong","year":"2014","journal-title":"J. Phys. Chem. B."},{"issue":"27","key":"10.1016\/j.jmr.2026.108153_bb0055","doi-asserted-by":"crossref","first-page":"9277","DOI":"10.1002\/chem.201601211","article-title":"A new Ir-NHC catalyst for signal amplification by reversible exchange in D2O","volume":"22","author":"Spannring","year":"2016","journal-title":"Chem. Eur. J."},{"key":"10.1016\/j.jmr.2026.108153_bb0060","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.jmr.2013.09.012","article-title":"Optimization of SABRE for polarization of the tuberculosis drugs pyrazinamide and isoniazid","volume":"237","author":"Zeng","year":"2013","journal-title":"J. Magn. Reson."},{"issue":"1","key":"10.1016\/j.jmr.2026.108153_bb0065","doi-asserted-by":"crossref","first-page":"eaao6250","DOI":"10.1126\/sciadv.aao6250","article-title":"Using Para hydrogen to hyperpolarize amines, amides, carboxylic acids, alcohols, phosphates, and carbonates","volume":"4","author":"Iali","year":"2018","journal-title":"Sci. Adv."},{"issue":"10","key":"10.1016\/j.jmr.2026.108153_bb0070","doi-asserted-by":"crossref","first-page":"1961","DOI":"10.1021\/acs.jpclett.5b00782","article-title":"Hyperpolarization of \u201cneat\u201d liquids by NMR signal amplification by reversible exchange","volume":"6","author":"Shchepin","year":"2015","journal-title":"J. Phys. Chem. Lett."},{"issue":"30","key":"10.1016\/j.jmr.2026.108153_bb0075","doi-asserted-by":"crossref","first-page":"13759","DOI":"10.1039\/c1cp20992b","article-title":"Para-hydrogen induced polarization of amino acids, peptides and deuterium\u2013hydrogen gas","volume":"13","author":"Gl\u00f6ggler","year":"2011","journal-title":"Phys. Chem. Chem. Phys."},{"issue":"15","key":"10.1016\/j.jmr.2026.108153_bb0080","doi-asserted-by":"crossref","DOI":"10.3390\/molecules25153347","article-title":"Hyperpolarization of nitrile compounds using signal amplification by reversible exchange","volume":"25","author":"Kim","year":"2020","journal-title":"Molecules"},{"issue":"20","key":"10.1016\/j.jmr.2026.108153_bb0085","doi-asserted-by":"crossref","first-page":"6478","DOI":"10.1039\/D0AN00967A","article-title":"Analysis of 1-aminoisoquinoline using the signal amplification by reversible exchange hyperpolarization technique","volume":"145","author":"Jeong","year":"2020","journal-title":"Analyst"},{"issue":"5","key":"10.1016\/j.jmr.2026.108153_bb0090","doi-asserted-by":"crossref","first-page":"1112","DOI":"10.1021\/acs.jpclett.7b03026","article-title":"SABRE-relay: a versatile route to hyperpolarization","volume":"9","author":"Roy","year":"2018","journal-title":"J. Phys. Chem. Lett."},{"issue":"7","key":"10.1016\/j.jmr.2026.108153_bb0095","doi-asserted-by":"crossref","first-page":"2695","DOI":"10.1021\/ja412994k","article-title":"Toward nanomolar detection by NMR through SABRE hyperpolarization","volume":"136","author":"Eshuis","year":"2014","journal-title":"J. Am. Chem. Soc."},{"issue":"4","key":"10.1016\/j.jmr.2026.108153_bb0100","doi-asserted-by":"crossref","first-page":"1404","DOI":"10.1021\/ja512242d","article-title":"Microtesla SABRE enables 10% Nitrogen-15 nuclear spin polarization","volume":"137","author":"Theis","year":"2015","journal-title":"J. Am. Chem. Soc."},{"issue":"16","key":"10.1016\/j.jmr.2026.108153_bb0105","doi-asserted-by":"crossref","first-page":"8786","DOI":"10.1021\/acs.jpcc.5b01799","article-title":"15N hyperpolarization by reversible exchange using SABRE-SHEATH","volume":"119","author":"Truong","year":"2015","journal-title":"J. Phys. Chem. C"},{"issue":"26","key":"10.1016\/j.jmr.2026.108153_bb0110","doi-asserted-by":"crossref","first-page":"8080","DOI":"10.1021\/jacs.6b04784","article-title":"Over 20% 15N hyperpolarization in under one minute for metronidazole, an antibiotic and hypoxia probe","volume":"138","author":"Barskiy","year":"2016","journal-title":"J. Am. Chem. Soc."},{"issue":"30","key":"10.1016\/j.jmr.2026.108153_bb0115","doi-asserted-by":"crossref","first-page":"10377","DOI":"10.1002\/ange.201905483","article-title":"Hyperpolarising pyruvate through signal amplification by reversible exchange (SABRE)","volume":"131","author":"Iali","year":"2019","journal-title":"Angew. Chem."},{"issue":"36","key":"10.1016\/j.jmr.2026.108153_bb0120","doi-asserted-by":"crossref","DOI":"10.1002\/anie.202306654","article-title":"In vivo metabolic imaging of [1-13C] pyruvate-d3 hyperpolarized by reversible exchange with parahydrogen","volume":"62","author":"de Maissin","year":"2023","journal-title":"Angew. Chem. Int. Ed."},{"issue":"7","key":"10.1016\/j.jmr.2026.108153_bb0125","doi-asserted-by":"crossref","first-page":"4377","DOI":"10.1039\/D2RA00062H","article-title":"Hyperpolarization study on remdesivir with its biological reaction monitoring via signal amplification by reversible exchange","volume":"12","author":"Jeong","year":"2022","journal-title":"RSC Adv."},{"issue":"1","key":"10.1016\/j.jmr.2026.108153_bb0130","doi-asserted-by":"crossref","first-page":"14290","DOI":"10.1038\/s41598-020-71282-6","article-title":"Signal amplification by reversible exchange for COVID-19 antiviral drug candidates","volume":"10","author":"Jeong","year":"2020","journal-title":"Sci. Rep."},{"issue":"2","key":"10.1016\/j.jmr.2026.108153_bb0135","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1021\/acsmeasuresciau.2c00065","article-title":"Real-time reaction monitoring of azide\u2013alkyne cycloadditions using benchtop NMR-based signal amplification by reversible exchange (SABRE)","volume":"3","author":"Jeong","year":"2023","journal-title":"ACS Meas. Sci. Au"},{"issue":"31","key":"10.1016\/j.jmr.2026.108153_bb0140","doi-asserted-by":"crossref","first-page":"11613","DOI":"10.1021\/acs.analchem.3c01049","article-title":"SABRE hyperpolarization of exchangeable protons in methanol\u2011d 4 through dynamic covalent bonds","volume":"95","author":"Zhan","year":"2023","journal-title":"Anal. Chem."},{"issue":"10","key":"10.1016\/j.jmr.2026.108153_bb0145","doi-asserted-by":"crossref","first-page":"2912","DOI":"10.1021\/jacsau.3c00487","article-title":"Water-compatible and recyclable heterogeneous SABRE catalyst for NMR signal amplification","volume":"3","author":"Min","year":"2023","journal-title":"JACS Au"},{"issue":"7","key":"10.1016\/j.jmr.2026.108153_bb0150","doi-asserted-by":"crossref","first-page":"2368","DOI":"10.1039\/D0AN02372H","article-title":"Optimization of signal amplification by reversible exchange for polarization of tridentate chelating bis [(2-pyridyl) alkyl] amine","volume":"146","author":"Min","year":"2021","journal-title":"Analyst"},{"issue":"59","key":"10.1016\/j.jmr.2026.108153_bb0155","doi-asserted-by":"crossref","first-page":"11061","DOI":"10.1039\/D5CC00544B","article-title":"Parahydrogen-induced hyperpolarization of a Zn (ii) complex using NMR signal amplification by reversible exchange (SABRE)","volume":"61","author":"Kim","year":"2025","journal-title":"Chem. Commun."},{"issue":"35","key":"10.1016\/j.jmr.2026.108153_bb0160","doi-asserted-by":"crossref","first-page":"11140","DOI":"10.1002\/anie.201711842","article-title":"Parahydrogen-based hyperpolarization for biomedicine","volume":"57","author":"H\u00f6vener","year":"2018","journal-title":"Angew. Chem. Int. Ed."},{"issue":"23","key":"10.1016\/j.jmr.2026.108153_bb0165","doi-asserted-by":"crossref","first-page":"6742","DOI":"10.1002\/anie.201710406","article-title":"Signal amplification by reversible exchange (SABRE): from discovery to diagnosis","volume":"57","author":"Rayner","year":"2018","journal-title":"Angew. Chem. Int. Ed."},{"issue":"10","key":"10.1016\/j.jmr.2026.108153_bb0170","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1002\/mrc.4280","article-title":"Developments and advances concerning the hyperpolarisation technique SABRE","volume":"53","author":"Mewis","year":"2015","journal-title":"Magn. Reson. Chem."},{"issue":"14","key":"10.1016\/j.jmr.2026.108153_bb0175","doi-asserted-by":"crossref","first-page":"3327","DOI":"10.1002\/cphc.201300595","article-title":"Level anti-crossings are a key factor for understanding Para-hydrogen-induced hyperpolarization in SABRE experiments","volume":"14","author":"Pravdivtsev","year":"2013","journal-title":"ChemPhysChem"},{"issue":"29","key":"10.1016\/j.jmr.2026.108153_bb0180","doi-asserted-by":"crossref","first-page":"10482","DOI":"10.1002\/chem.201500714","article-title":"Computational (DFT) and experimental (EXAFS) study of the interaction of [Ir (IMes)(H) 2 (L) 3] with substrates and co-substrates relevant for SABRE in dilute systems","volume":"21","author":"Van Weerdenburg","year":"2015","journal-title":"Chem. Eur. J."},{"issue":"19","key":"10.1016\/j.jmr.2026.108153_bb0185","doi-asserted-by":"crossref","first-page":"1947","DOI":"10.1002\/cphc.202100204","article-title":"Density functional theory study of reaction equilibria in signal amplification by reversible exchange","volume":"22","author":"Lin","year":"2021","journal-title":"ChemPhysChem"},{"key":"10.1016\/j.jmr.2026.108153_bb0190","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.pnmrs.2019.05.005","article-title":"SABRE: chemical kinetics and spin dynamics of the formation of hyperpolarization","volume":"114","author":"Barskiy","year":"2019","journal-title":"Prog. Nucl. Magn. Reson. Spectrosc."},{"issue":"4","key":"10.1016\/j.jmr.2026.108153_bb0195","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1002\/open.201900076","article-title":"Steric and electronic effects in gold N-heterocyclic carbene complexes revealed by computational analysis","volume":"8","author":"de Kock","year":"2019","journal-title":"ChemistryOpen"},{"issue":"40","key":"10.1016\/j.jmr.2026.108153_bb0200","doi-asserted-by":"crossref","first-page":"15198","DOI":"10.1039\/C9DT02951F","article-title":"Mechanistic insight into novel sulfoxide containing SABRE polarisation transfer catalysts","volume":"48","author":"Tickner","year":"2019","journal-title":"Dalton Trans."}],"container-title":["Journal of Magnetic Resonance"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1090780726001424?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1090780726001424?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T07:08:56Z","timestamp":1790838536000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1090780726001424"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":40,"alternative-id":["S1090780726001424"],"URL":"https:\/\/doi.org\/10.1016\/j.jmr.2026.108153","relation":{},"ISSN":["1090-7807"],"issn-type":[{"value":"1090-7807","type":"print"}],"subject":[],"published":{"date-parts":[[2026,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Efficient iridium N-heterocyclic carbene catalysts for signal amplification by reversible exchange in dimethyl sulfoxide","name":"articletitle","label":"Article Title"},{"value":"Journal of Magnetic Resonance","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jmr.2026.108153","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"108153"}}